Versus

Mary Kay TimeWise Repair Volu-Firm® Advanced Lifting Serum Versus Peter Thomas Roth Peptide 21 Wrinkle Resist Serum

Serum
Serum
American Brand United States
American Brand United States

Updated on February 06, 2025

Overview

What they are

These products are both serums. They have a total of 11 ingredients in common

Cool Features

They both contain exfoliants, peptides and Vitamin E

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, reducing pores and scar healing

Free From

They both do not contain any oils or parabens

What's Inside

They both contain silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
TimeWise Repair Volu-Firm® Advanced Lifting Serum

Cyclopentasiloxane

Emollient
Silicon Icon

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Silica

Abrasive
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon

PEG-10 Dimethicone

Skin Conditioning
Silicon Icon

Polymethylsilsesquioxane

Silicon Icon

Dimethicone

Emollient
1 / 0 Silicon Icon

Polysilicone-11

Pentylene Glycol

Skin Conditioning

Hdi/Trimethylol Hexyllactone Crosspolymer

Caprylic/Capric Triglyceride

Masking

Secale Cereale Seed Extract

Abrasive
Exfoliant Icon

Alpinia Galanga Leaf Extract

Skin Conditioning

Schisandra Chinensis Fruit Extract

Skin Conditioning

Centella Asiatica Meristem Cell Culture

Antioxidant
Antioxidant Icon

Pisum Sativum Extract

Skin Conditioning

Lavandula Angustifolia Flower/Leaf/Stem Extract

Masking
Fragrance Icon

Alteromonas Ferment Filtrate

Humectant

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Prunus Persica Fruit Extract

Abrasive
Exfoliant Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Tripeptide-1

Skin Conditioning
Peptide IconHelps with Anti-Aging Icon

Sorbitol

Humectant
0 / 0 Helps hydrate Dry Skin Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Polysorbate 40

Emulsifying
Not safe for Fungal Acne Icon

Menthyl Lactate

Masking

Rose Extract

Skin Conditioning

Cucumis Sativus Fruit Extract

Emollient

Vanilla Planifolia Fruit Extract

Skin Conditioning

Jasminum Officinale Flower/Leaf Extract

Masking
Fragrance Icon

Fucus Vesiculosus Extract

Emollient
Helps hydrate Dry Skin Icon

Passiflora Edulis Fruit Extract

Skin Conditioning

Prunus Armeniaca Fruit Extract

Skin Conditioning

Mentha Piperita Extract

Cleansing

Rosmarinus Officinalis Leaf Extract

Antimicrobial

Pyrus Malus Fruit Extract

Skin Conditioning

Santalum Album Wood Extract

Perfuming
Fragrance Icon

Citrus Aurantium Bergamia Fruit Extract

Skin Conditioning

Cananga Odorata Flower Extract

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Rubus Idaeus Fruit Extract

Astringent

Coriandrum Sativum Fruit/Leaf Extract

Antiseborrhoeic

Cupressus Sempervirens Leaf/Stem Extract

Skin Conditioning

Cucumis Melo Cantalupensis Fruit Extract

Astringent

Sodium Chloride

Masking
Can worsen Dry Skin IconBad for Acne Prone Skin IconMay worsen Rosacea Icon

Cyclohexasiloxane

Emollient
Silicon Icon

Disodium EDTA

Triethanolamine

Buffering
2 / 0

Dihydroxy Methylchromone

Antioxidant
Antioxidant Icon

Sodium Citrate

Buffering

Xanthan Gum

Emulsifying

Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate

Skin Conditioning

Hydroxypropyl Cyclodextrin

Masking

Alcohol

Antimicrobial
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon

Phenoxyethanol

Preservative
Preservative Icon

Caprylyl Glycol

Emollient

Iodopropynyl Butylcarbamate

Preservative
Preservative Icon

Chlorphenesin

Antimicrobial
Preservative Icon

Tin Oxide

Abrasive
Exfoliant Icon

Mica

Cosmetic Colorant
May worsen Eczema Icon

Titanium Dioxide

Cosmetic Colorant
0 / 0 Mineral UV Filter IconNon-Reef-Safe Icon

Cyclodextrin

Absorbent

Maltodextrin

Absorbent

Magnesium Chloride

Cyclopentasiloxane, Water, Glycerin, Silica, PEG-10 Dimethicone, Polymethylsilsesquioxane, Dimethicone, Polysilicone-11, Pentylene Glycol, Hdi/Trimethylol Hexyllactone Crosspolymer, Caprylic/Capric Triglyceride, Secale Cereale Seed Extract, Alpinia Galanga Leaf Extract, Schisandra Chinensis Fruit Extract, Centella Asiatica Meristem Cell Culture, Pisum Sativum Extract, Lavandula Angustifolia Flower/Leaf/Stem Extract, Alteromonas Ferment Filtrate, Camellia Sinensis Leaf Extract, Prunus Persica Fruit Extract, Tocopherol, Tripeptide-1, Sorbitol, Butylene Glycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Polysorbate 40, Menthyl Lactate, Rose Extract, Cucumis Sativus Fruit Extract, Vanilla Planifolia Fruit Extract, Jasminum Officinale Flower/Leaf Extract, Fucus Vesiculosus Extract, Passiflora Edulis Fruit Extract, Prunus Armeniaca Fruit Extract, Mentha Piperita Extract, Rosmarinus Officinalis Leaf Extract, Pyrus Malus Fruit Extract, Santalum Album Wood Extract, Citrus Aurantium Bergamia Fruit Extract, Cananga Odorata Flower Extract, Rubus Idaeus Fruit Extract, Coriandrum Sativum Fruit/Leaf Extract, Cupressus Sempervirens Leaf/Stem Extract, Cucumis Melo Cantalupensis Fruit Extract, Sodium Chloride, Cyclohexasiloxane, Disodium EDTA, Triethanolamine, Dihydroxy Methylchromone, Sodium Citrate, Xanthan Gum, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Hydroxypropyl Cyclodextrin, Alcohol, Phenoxyethanol, Caprylyl Glycol, Iodopropynyl Butylcarbamate, Chlorphenesin, Tin Oxide, Mica, Titanium Dioxide, Cyclodextrin, Maltodextrin, Magnesium Chloride

Peptide 21 Wrinkle Resist Serum

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Rosa Centifolia Flower Water

Skin Conditioning

Isopropyl Myristate

Emollient
3-5 / 3 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Mannitol

Humectant

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Natto Gum

Tripeptide-10 Citrulline

Skin Conditioning
Peptide Icon

Acetyl Octapeptide-3

Humectant
Peptide Icon

Palmitoyl Hexapeptide-12

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Acetyl Tetrapeptide-11

Skin Conditioning
Peptide Icon

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps with Anti-Aging Icon

Acetyl Hexapeptide-1

Skin Conditioning
Peptide Icon

Palmitoyl Oligopeptide

Cleansing
Peptide IconNot safe for Fungal Acne Icon

Acetyl Tetrapeptide-9

Skin Conditioning
Peptide Icon

Acetyl Tetrapeptide-2

Skin Conditioning
Peptide Icon

Tripeptide-1

Skin Conditioning
Peptide IconHelps with Anti-Aging Icon

Palmitoyl Tetrapeptide-7

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Hexapeptide-11

Skin Conditioning
Peptide Icon

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Skin Conditioning
Peptide Icon

Palmitoyl Tripeptide-5

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Trifluoroacetyl Tripeptide-2

Skin Conditioning
Peptide Icon

Palmitoyl Tripeptide-1

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Sodium Polyglutamate

Humectant

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Retinyl Palmitate

Skin Conditioning
1-3 / 1-3 Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconNot safe for Fungal Acne IconMay worsen Rosacea Icon

Ascorbic Acid

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon

Hydrolyzed Soy Protein

Humectant

Hydrolyzed Wheat Protein

Skin Conditioning

Lecithin

Emollient

Pseudoalteromonas Ferment Extract

Humectant
Not safe for Fungal Acne Icon

Acrylates Copolymer

Magnesium Chloride

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Dimethyl Isosorbide

Solvent

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Leuconostoc/Radish Root Ferment Filtrate

Antimicrobial
Not safe for Fungal Acne Icon

PEG-8 Dimethicone

Emulsifying
Silicon Icon

Disodium Phosphate

Buffering

Carbomer

Emulsion Stabilising
1 / 0

Dextran

Sodium Lactate

Buffering

Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate

Skin Conditioning

Xanthan Gum

Emulsifying

Triethanolamine

Buffering
2 / 0

Sodium Phosphate

Buffering

Octyldodecanol

Emollient

Silica

Abrasive
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon

Sodium Propoxyhydroxypropyl Thiosulfate Silica

Sulfate Icon

Sodium Hydroxide

Buffering

Caprylyl Glycol

Emollient

Potassium Sorbate

Preservative
Preservative Icon

Sodium Benzoate

Masking
Preservative Icon

Phenoxyethanol

Preservative
Preservative Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Abrasive, Absorbent

Silica is a mineral naturally found in our skin. It helps to thicken and smooth the texture of a product. It also acts as an agent for other ingredients by increasing the absorption of other ingredients into the skin.

Silica is often used for absorption and can help reduce shine when products are applied. Silica occurs in naturally in materials like clay and sandstone, and it can also be produced synthetically.

Silica is present naturally within the skin during collagen production and when reducing inflammation.

Learn more about Silica
Skin Conditioning, Skin Protecting

Tripeptide-1 is a peptide. It can help to reduce the effects of aging.

Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

  • It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
  • It is a humectant, which means that it helps attract moisture into the skin.
  • It helps improve product application.
  • It has mild preservative properties.

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Buffering, Emulsifying, Masking

Triethanolamine is an emulsifier and pH adjuster. It is created using ethylene oxide and ammonia. This gives Triethanolamine a nitrogen core and a similar scent to ammonia.

As an emulsifier, it prevents ingredients from separating and enhances texture by adding volume to a product.

PH adjusters are common in cosmetic products. The pH of a product can affect the effectiveness of other ingredients. A product with a high pH may also irritate the skin.

Learn more about Triethanolamine
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum

We don't have a description for Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate yet.

Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol

We don't have a description for Magnesium Chloride yet.

When to use

10 Routines
60% use in am
40% use in pm
90% use every day
18 Routines
56% use in am
44% use in pm
89% use every day