Missha Time Revolution Night Repair Probio Ampoule Versus Lancôme Advanced Génifique Youth Activating Concentrate
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningBifida Ferment Lysate
Skin Conditioning
Glycereth-26
Humectant
Sorbus Commixta Extract
Skin ConditioningJuniperus Chinensis Xylem Extract
Skin ConditioningBis-PEG-18 Methyl Ether Dimethyl Silane
EmollientButylene Glycol
Humectant
Glycerin
Humectant
Niacinamide
Smoothing
Leuconostoc Ferment Filtrate
AntimicrobialBetaine
Humectant
Grifola Frondosa/Ophioglossum Vulgatum Extract Ferment Filtrate
Skin ConditioningLactobacillus/Rice Ferment Filtrate
Skin ConditioningPortulaca Oleracea Extract
Skin Conditioning
Sodium Hyaluronate
Humectant
Anthemis Nobilis Flower Extract
Masking
Hydrolyzed Rice Extract
Skin Conditioning
Sea Water
HumectantCarthamus Tinctorius Oleosomes
Emollient
Hydrolyzed Extensin
Skin ConditioningAdenosine
Skin Conditioning
Daucus Carota Sativa Root Extract
Skin Conditioning
Vaccinium Angustifolium Fruit Extract
Skin Protecting
Beta Vulgaris Root Extract
Skin ConditioningAronia Arbutifolia Extract
Skin ConditioningBrassica Oleracea Capitata Leaf Extract
Skin ConditioningEchium Plantagineum Seed Oil
Skin Conditioning
Ascorbyl Tetraisopalmitate
Antioxidant
Lactobacillus Ferment
Skin Conditioning
Lactococcus Ferment Lysate
Skin Conditioning
Manilkara Multinervis Leaf Extract
Skin ConditioningTheobroma Cacao Seed Extract
Antioxidant
Cassia Alata Leaf Extract
AstringentLaminaria Digitata Extract
Skin Protecting
Saccharomyces Ferment Filtrate
Humectant
Lactobacillus/Soybean Ferment Extract
Skin ConditioningSaccharomyces/Viscum Album Ferment Extract
Skin Conditioning
Yeast Ferment Extract
Skin ConditioningPogostemon Cablin Leaf Oil
Masking
Pseudoalteromonas Ferment Extract
Humectant
Cardiospermum Halicacabum Flower/Leaf/Vine Extract
Skin ConditioningHelianthus Annuus Seed Oil Unsaponifiables
Emollient
Alpha-Glucan Oligosaccharide
Cleansing
Limnanthes Alba Seed Oil
Skin Conditioning
Hydrolyzed Wheat Protein
Skin ConditioningBeta-Sitosterol
Emulsion Stabilising
Panthenol
Skin Conditioning
Hydrolyzed Soy Protein
Humectant
Ubiquinone
Antioxidant
Macadamia Ternifolia Seed Oil
Emollient
Retinol
Skin Conditioning
Cucumis Melo Fruit Extract
Skin ConditioningBiotin
AntiseborrhoeicBrassica Campestris Sterols
EmollientSodium Ascorbyl Phosphate
Antioxidant
Amaranthus Caudatus Seed Extract
Skin Conditioning
Tripeptide-10 Citrulline
Skin Conditioning
Acetyl Hexapeptide-8
Humectant
Copper Tripeptide-1
Skin Conditioning
Tripeptide-1
Skin Conditioning
Acacia Arabica Stem Bark Extract
Skin ConditioningCholesterol
Emollient
Glyceryl Linolenate
Emollient
Glyceryl Linoleate
Emollient
Glyceryl Arachidonate
Emollient
Cyclopentasiloxane
Emollient
Ethyl Hexanediol
SolventDimethicone
Emollient
PEG-11 Methyl Ether Dimethicone
Emulsifying
PEG-40 Hydrogenated Castor Oil
Emulsifying
PPG-26-Buteth-26
Skin ConditioningPolysorbate 20
Emulsifying
Carbomer
Emulsion StabilisingGlyceryl Caprylate
EmollientTriethanolamine
BufferingDimethicone/Vinyl Dimethicone Crosspolymer
Skin Conditioning
Octyldodecanol
Emollient
Xanthan Gum
EmulsifyingDipropylene Glycol
HumectantCyclomethicone
Emollient
Hydrogenated Lecithin
Emulsifying
Disodium EDTA
Dextrin
AbsorbentLauryl Methacrylate/Glycol Dimethacrylate Crosspolymer
Glyceryl Polyacrylate
Dimethiconol
Emollient
Propylene Glycol
Humectant
Ceteth-24
CleansingCholeth-24
EmulsifyingHydroxypropyltrimonium Maltodextrin Crosspolymer
SurfactantCetyl Phosphate
EmulsifyingCaprylic/Capric Triglyceride
Masking
Lecithin
Emollient
PEG-5 Rapeseed Sterol
Cleansing
BHT
Antioxidant
Ceteth-3
EmulsifyingCeteth-5
EmulsifyingSilica
Abrasive
Tocopheryl Acetate
Antioxidant
Phenoxyethanol
Preservative
Water, Bifida Ferment Lysate, Glycereth-26, Sorbus Commixta Extract, Juniperus Chinensis Xylem Extract, Bis-PEG-18 Methyl Ether Dimethyl Silane, Butylene Glycol, Glycerin, Niacinamide, Leuconostoc Ferment Filtrate, Betaine, Grifola Frondosa/Ophioglossum Vulgatum Extract Ferment Filtrate, Lactobacillus/Rice Ferment Filtrate, Portulaca Oleracea Extract, Sodium Hyaluronate, Anthemis Nobilis Flower Extract, Hydrolyzed Rice Extract, Sea Water, Carthamus Tinctorius Oleosomes, Hydrolyzed Extensin, Adenosine, Daucus Carota Sativa Root Extract, Vaccinium Angustifolium Fruit Extract, Beta Vulgaris Root Extract, Aronia Arbutifolia Extract, Brassica Oleracea Capitata Leaf Extract, Echium Plantagineum Seed Oil, Ascorbyl Tetraisopalmitate, Lactobacillus Ferment, Lactococcus Ferment Lysate, Manilkara Multinervis Leaf Extract, Theobroma Cacao Seed Extract, Cassia Alata Leaf Extract, Laminaria Digitata Extract, Saccharomyces Ferment Filtrate, Lactobacillus/Soybean Ferment Extract, Saccharomyces/Viscum Album Ferment Extract, Yeast Ferment Extract, Pogostemon Cablin Leaf Oil, Pseudoalteromonas Ferment Extract, Cardiospermum Halicacabum Flower/Leaf/Vine Extract, Helianthus Annuus Seed Oil Unsaponifiables, Alpha-Glucan Oligosaccharide, Limnanthes Alba Seed Oil, Hydrolyzed Wheat Protein, Beta-Sitosterol, Panthenol, Hydrolyzed Soy Protein, Ubiquinone, Macadamia Ternifolia Seed Oil, Retinol, Cucumis Melo Fruit Extract, Biotin, Brassica Campestris Sterols, Sodium Ascorbyl Phosphate, Amaranthus Caudatus Seed Extract, Tripeptide-10 Citrulline, Acetyl Hexapeptide-8, Copper Tripeptide-1, Tripeptide-1, Acacia Arabica Stem Bark Extract, Cholesterol, Glyceryl Linolenate, Glyceryl Linoleate, Glyceryl Arachidonate, Cyclopentasiloxane, Ethyl Hexanediol, Dimethicone, PEG-11 Methyl Ether Dimethicone, PEG-40 Hydrogenated Castor Oil, PPG-26-Buteth-26, Polysorbate 20, Carbomer, Glyceryl Caprylate, Triethanolamine, Dimethicone/Vinyl Dimethicone Crosspolymer, Octyldodecanol, Xanthan Gum, Dipropylene Glycol, Cyclomethicone, Hydrogenated Lecithin, Disodium EDTA, Dextrin, Lauryl Methacrylate/Glycol Dimethacrylate Crosspolymer, Glyceryl Polyacrylate, Dimethiconol, Propylene Glycol, Ceteth-24, Choleth-24, Hydroxypropyltrimonium Maltodextrin Crosspolymer, Cetyl Phosphate, Caprylic/Capric Triglyceride, Lecithin, PEG-5 Rapeseed Sterol, BHT, Ceteth-3, Ceteth-5, Silica, Tocopheryl Acetate, Phenoxyethanol
Water
Skin ConditioningBifida Ferment Lysate
Skin Conditioning
Glycerin
Humectant
Alcohol Denat.
Antimicrobial
Dimethicone
Emollient
Hydroxyethylpiperazine Ethane Sulfonic Acid
BufferingAscorbyl Glucoside
Antioxidant
Sodium Hyaluronate
Humectant
Sodium Hydroxide
BufferingSodium Benzoate
Masking
Phenoxyethanol
Preservative
Adenosine
Skin Conditioning
Yeast Extract
Skin ConditioningPEG-20 Methyl Glucose Sesquistearate
Emulsifying
PEG-60 Hydrogenated Castor Oil
Emulsifying
Salicyloyl Phytosphingosine
Skin ConditioningAmmonium Polyacryloyldimethyl Taurate
Emulsion StabilisingLimonene
Perfuming
Xanthan Gum
EmulsifyingCaprylyl Glycol
Emollient
Disodium EDTA
Octyldodecanol
Emollient
Citronellol
Perfuming
Parfum
Masking
Water, Bifida Ferment Lysate, Glycerin, Alcohol Denat., Dimethicone, Hydroxyethylpiperazine Ethane Sulfonic Acid, Ascorbyl Glucoside, Sodium Hyaluronate, Sodium Hydroxide, Sodium Benzoate, Phenoxyethanol, Adenosine, Yeast Extract, PEG-20 Methyl Glucose Sesquistearate, PEG-60 Hydrogenated Castor Oil, Salicyloyl Phytosphingosine, Ammonium Polyacryloyldimethyl Taurate, Limonene, Xanthan Gum, Caprylyl Glycol, Disodium EDTA, Octyldodecanol, Citronellol, Parfum
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineBifida Ferment Lysate is a postbiotic ingredient made by fermenting Bifidobacterium to extract a nutrient-rich mix of peptides, amino acids, vitamins, organic acids, and polysaccharides.
These components are basically the building blocks that your skin already uses to stay hydrated, repair itself, and maintain its barrier. That's why this ingredient helps your skin hold onto moisture and stay resilient against irritation.
One in-vitro study found that this ingredient tells your skin cells to produce more of the proteins (filaggrin, loricrin, and involucrin) for building a strong and healthy barrier. This study also found this ingredient to be a solid antioxidant that helped neutralize damage against UV and pollution.
A study with people from 2010 found that sensitive, reactive skin using a cream with 10% of this ingredient for a month became noticeably less dry, less reactive, and harder to irritate compared to the group using a plain cream.
In short, this ingredient is a well-tolerated ingredient that can help with barrier repair, antioxidant protection, and calming reactive skin.
This ingredient is generally considered fungal acne (Malassezia) safe; Bifidobacterium is a bacterium, not a yeast or fungus.
The fungal acne concern with fermented ingredients mainly applies to yeast-derived ferments like Saccharomyces and Galactomyces, because those are in the same kingdom as Malassezia and could theoretically contain residual compounds that feed it.
Bifida is a completely different organism, so on its own it doesn't provide a food source for the Malassezia yeast that causes fungal acne.
Learn more about Bifida Ferment LysateDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinOctyldodecanol is a fatty alcohol sourced from plant oils like coconut or palm (or made synthetically).
It is:
You'll likely see this in many BHA products because this is the go-to solvent for salicylic acid.
This ingredient is typically used at levels between 2-20%.
Regarding fungal acne:
In 2019, this ingredient was tested against multiple Malassezia species (the yeast that causes fungal acne) and showed no growth.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan Gum
