MediCube PDRN Pink Collagen Exosome Shot 2000 Versus Numbuzin 9+ NAD Bio Lifting-Sil Essence
Updated on February 06, 2025
Overview
What they are
These products are both cruelty-free and reef safe . They have a total of 17 ingredients in common
Cool Features
They both contain hyaluronic acid, niacinamide, peptides and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any common allergens, fragrances, parabens or sulfates
What's Inside
They both contain oils and silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
MediCube PDRN Pink Collagen Exosome Shot 2000 50 ingredients
Numbuzin 9+ NAD Bio Lifting-Sil Essence 120 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
MediCube PDRN Pink Collagen Exosome Shot 2000 50 ingredients
Numbuzin 9+ NAD Bio Lifting-Sil Essence 120 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningButylene Glycol
Humectant
Dipropylene Glycol
MaskingGlycerin
Humectant
Niacinamide
Smoothing
Sodium Polyacrylate
Absorbent1,2-Hexanediol
Skin ConditioningCaprylyl Glycol
EmollientCetearyl Olivate
Phenyl Trimethicone
Skin Conditioning
Sorbitan Olivate
Emulsifying
Hydrolyzed Sponge
Skin ConditioningGlyceryl Acrylate/Acrylic Acid Copolymer
HumectantEthylhexylglycerin
Skin ConditioningCalcium Aluminum Borosilicate
Adenosine
Skin Conditioning
Disodium EDTA
Pvm/Ma Copolymer
Emulsion StabilisingPanthenol
Skin Conditioning
Rosa Damascena Callus Extracellular Vesicles
Skin ConditioningCyanocobalamin
Skin ConditioningSodium Dna
Skin ConditioningMilk Exosomes
EmollientCollagen Extract
Skin Conditioning
Macadamia Ternifolia Seed Oil
Emollient
Caprylic/Capric Triglyceride
MaskingAlcohol Denat.
Antimicrobial
Hydrogenated Lecithin
EmulsifyingPolysorbate 20
Emulsifying
Retinol
Skin Conditioning
Chondrus Crispus Extract
Skin Conditioning
Cholesterol
Emollient
Sodium Hyaluronate
Humectant
PEG-5 Rapeseed Sterol
Cleansing
Polyglyceryl-10 Laurate
Skin Conditioning
Ceteth-3
EmulsifyingCeteth-5
EmulsifyingTocopheryl Acetate
Antioxidant
Hydrolyzed Elastin
EmollientPotassium Cetyl Phosphate
EmulsifyingHydroxypropyltrimonium Hyaluronate
Acetyl Tetrapeptide-5
Humectant
Palmitoyl Pentapeptide-4
Skin Conditioning
Sodium Acetylated Hyaluronate
Humectant
Hydrolyzed Hyaluronic Acid
Humectant
Palmitoyl Tripeptide-5
Skin Conditioning
Hyaluronic Acid
Humectant
Sodium Hyaluronate Crosspolymer
Humectant
Hydrolyzed Sodium Hyaluronate
Skin ConditioningPotassium Hyaluronate
Skin ConditioningWater, Butylene Glycol, Dipropylene Glycol, Glycerin, Niacinamide, Sodium Polyacrylate, 1,2-Hexanediol, Caprylyl Glycol, Cetearyl Olivate, Phenyl Trimethicone, Sorbitan Olivate, Hydrolyzed Sponge, Glyceryl Acrylate/Acrylic Acid Copolymer, Ethylhexylglycerin, Calcium Aluminum Borosilicate, Adenosine, Disodium EDTA, Pvm/Ma Copolymer, Panthenol, Rosa Damascena Callus Extracellular Vesicles, Cyanocobalamin, Sodium Dna, Milk Exosomes, Collagen Extract, Macadamia Ternifolia Seed Oil, Caprylic/Capric Triglyceride, Alcohol Denat., Hydrogenated Lecithin, Polysorbate 20, Retinol, Chondrus Crispus Extract, Cholesterol, Sodium Hyaluronate, PEG-5 Rapeseed Sterol, Polyglyceryl-10 Laurate, Ceteth-3, Ceteth-5, Tocopheryl Acetate, Hydrolyzed Elastin, Potassium Cetyl Phosphate, Hydroxypropyltrimonium Hyaluronate, Acetyl Tetrapeptide-5, Palmitoyl Pentapeptide-4, Sodium Acetylated Hyaluronate, Hydrolyzed Hyaluronic Acid, Palmitoyl Tripeptide-5, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate
Water
Skin ConditioningGlycerin
Humectant
Hydrogenated Poly(C6-14 Olefin)
EmollientPolyglycerin-3
HumectantButylene Glycol
Humectant
Pentaerythrityl Tetraethylhexanoate
EmollientPropanediol
SolventDimethicone
Emollient
1,2-Hexanediol
Skin ConditioningNiacinamide
Smoothing
Methylpropanediol
SolventCetearyl Alcohol
Emollient
Glyceryl Stearate
Emollient
Hydrogenated Vegetable Oil
Emollient
Polyglyceryl-3 Methylglucose Distearate
Emulsifying
Butyrospermum Parkii Butter
Skin Conditioning
Dimethicone Crosspolymer
Emulsion StabilisingAmmonium Acryloyldimethyltaurate/Vp Copolymer
Sodium Polyacrylate
AbsorbentHydrogenated Lecithin
EmulsifyingCarbomer
Emulsion StabilisingXanthan Gum
EmulsifyingPentylene Glycol
Skin ConditioningTromethamine
BufferingEthylhexylglycerin
Skin ConditioningAdenosine
Skin Conditioning
Palmitic Acid
Emollient
Stearic Acid
Cleansing
Sodium Phytate
Cholesterol
Emollient
Sodium Hyaluronate
Humectant
Adenosine Triphosphate
Skin ConditioningHydroxypropyl Cyclodextrin
MaskingNicotinamide Adenine Dinucleotide
Skin ConditioningBeta-Glucan
Skin Conditioning
Tocopherol
Antioxidant
Palmitoyl Tripeptide-5
Skin Conditioning
Copper Gluconate
Skin ConditioningSaccharomyces/Copper Ferment
Skin ConditioningSaccharomyces/Iron Ferment
Skin ConditioningSaccharomyces/Magnesium Ferment
Saccharomyces/Silicon Ferment
Skin ConditioningSaccharomyces/Zinc Ferment
Skin ConditioningCapryloyl Dipeptide-17
Emollient
Thioctic Acid
Antioxidant
Leuconostoc/Radish Root Ferment Filtrate
Antimicrobial
Glutathione
Tremella Fuciformis Extract
HumectantHaematococcus Pluvialis Oil
Antioxidant
Potassium Hydroxide
BufferingResveratrol
Antioxidant
Hesperidin Methyl Chalcone
Antioxidant
Sorbitan Laurate
Emulsifying
Steareth-20
CleansingAstaxanthin
Skin ConditioningSodium Lactate
BufferingHydroxyethylcellulose
Emulsion StabilisingAcetyl Dipeptide-1 Cetyl Ester
Skin Conditioning
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning
Heptasodium Hexacarboxymethyl Dipeptide-12
Skin Conditioning
Panthenol
Skin Conditioning
Polysorbate 20
Emulsifying
Sodium Citrate
BufferingChlorhexidine Digluconate
Antimicrobial
Dextran
Hexapeptide-2
Bleaching
Magnesium Chloride
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate
Skin ConditioningAcetyl Tetrapeptide-5
Humectant
Dipeptide-2
Skin Conditioning
Potassium Sorbate
Preservative
Acetyl Hexapeptide-8
Humectant
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine
Skin Conditioning
Citric Acid
Buffering
Biotin
AntiseborrhoeicPalmitoyl Tetrapeptide-7
Skin Conditioning
Biotinoyl Tripeptide-1
Acetyl Tetrapeptide-3
Skin Protecting
Trifolium Pratense Flower Extract
Astringent
Tocopheryl Acetate
Antioxidant
Palmitoyl Tripeptide-8
Skin Conditioning
Dipeptide-4
Skin Conditioning
Hexapeptide-11
Skin Conditioning
Pentapeptide-18
Skin Conditioning
Tripeptide-3
Skin Conditioning
Sh-Decapeptide-7
Antioxidant
Sh-Octapeptide-4
Antioxidant
Palmitoyl Tripeptide-1
Skin Conditioning
Ascorbic Acid Polypeptide
Antioxidant
Hexapeptide-9
Skin Conditioning
Oligopeptide-3
Skin Conditioning
Palmitoyl Hexapeptide-12
Skin Conditioning
Tripeptide-1
Skin Conditioning
Palmitoyl Pentapeptide-4
Skin Conditioning
Ubiquinone
Antioxidant
Copper Tripeptide-1
Skin Conditioning
Caffeoyl Tripeptide-1
Antioxidant
Caffeoyl Sh-Octapeptide-4
Antioxidant
Galloyl Pentapeptide-33
Antioxidant
Kojyl Carboxy Dipeptide-23
Antioxidant
Nicotinoyl Tripeptide-1
Antioxidant
Octapeptide-7
Skin Protecting
Oligopeptide-1
Skin Conditioning
Sh-Decapeptide-9
Skin Conditioning
Sh-Oligopeptide-9
Humectant
Sh-Pentapeptide-19
Skin Conditioning
Asparagine
MaskingGlutamine
Skin ConditioningTryptophan
MaskingOligopeptide-2
Skin Conditioning
Sh-Oligopeptide-1
Skin Conditioning
Sh-Oligopeptide-2
Skin Conditioning
Sh-Polypeptide-1
Skin Conditioning
Sh-Polypeptide-22
Skin Conditioning
Sh-Polypeptide-3
Skin Conditioning
Acetyl Octapeptide-3
Humectant
Acetyl Tetrapeptide-2
Skin Conditioning
Acetyl Tetrapeptide-9
Skin Conditioning
Carnosine
Skin ConditioningNonapeptide-1
Skin Conditioning
Water, Glycerin, Hydrogenated Poly(C6-14 Olefin), Polyglycerin-3, Butylene Glycol, Pentaerythrityl Tetraethylhexanoate, Propanediol, Dimethicone, 1,2-Hexanediol, Niacinamide, Methylpropanediol, Cetearyl Alcohol, Glyceryl Stearate, Hydrogenated Vegetable Oil, Polyglyceryl-3 Methylglucose Distearate, Butyrospermum Parkii Butter, Dimethicone Crosspolymer, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Sodium Polyacrylate, Hydrogenated Lecithin, Carbomer, Xanthan Gum, Pentylene Glycol, Tromethamine, Ethylhexylglycerin, Adenosine, Palmitic Acid, Stearic Acid, Sodium Phytate, Cholesterol, Sodium Hyaluronate, Adenosine Triphosphate, Hydroxypropyl Cyclodextrin, Nicotinamide Adenine Dinucleotide, Beta-Glucan, Tocopherol, Palmitoyl Tripeptide-5, Copper Gluconate, Saccharomyces/Copper Ferment, Saccharomyces/Iron Ferment, Saccharomyces/Magnesium Ferment, Saccharomyces/Silicon Ferment, Saccharomyces/Zinc Ferment, Capryloyl Dipeptide-17, Thioctic Acid, Leuconostoc/Radish Root Ferment Filtrate, Glutathione, Tremella Fuciformis Extract, Haematococcus Pluvialis Oil, Potassium Hydroxide, Resveratrol, Hesperidin Methyl Chalcone, Sorbitan Laurate, Steareth-20, Astaxanthin, Sodium Lactate, Hydroxyethylcellulose, Acetyl Dipeptide-1 Cetyl Ester, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Heptasodium Hexacarboxymethyl Dipeptide-12, Panthenol, Polysorbate 20, Sodium Citrate, Chlorhexidine Digluconate, Dextran, Hexapeptide-2, Magnesium Chloride, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Acetyl Tetrapeptide-5, Dipeptide-2, Potassium Sorbate, Acetyl Hexapeptide-8, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Citric Acid, Biotin, Palmitoyl Tetrapeptide-7, Biotinoyl Tripeptide-1, Acetyl Tetrapeptide-3, Trifolium Pratense Flower Extract, Tocopheryl Acetate, Palmitoyl Tripeptide-8, Dipeptide-4, Hexapeptide-11, Pentapeptide-18, Tripeptide-3, Sh-Decapeptide-7, Sh-Octapeptide-4, Palmitoyl Tripeptide-1, Ascorbic Acid Polypeptide, Hexapeptide-9, Oligopeptide-3, Palmitoyl Hexapeptide-12, Tripeptide-1, Palmitoyl Pentapeptide-4, Ubiquinone, Copper Tripeptide-1, Caffeoyl Tripeptide-1, Caffeoyl Sh-Octapeptide-4, Galloyl Pentapeptide-33, Kojyl Carboxy Dipeptide-23, Nicotinoyl Tripeptide-1, Octapeptide-7, Oligopeptide-1, Sh-Decapeptide-9, Sh-Oligopeptide-9, Sh-Pentapeptide-19, Asparagine, Glutamine, Tryptophan, Oligopeptide-2, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-22, Sh-Polypeptide-3, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Acetyl Tetrapeptide-9, Carnosine, Nonapeptide-1
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
- It has mild preservative properties.
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinNiacinamide has emerged as an all-star ingredient due to its many benefits.
It is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging. And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all. If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body needs to convert it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideSodium Polyacrylate is the sodium salt of polyacrylic acid. It is used as an absorber, emollient, and stabilizer.
This ingredient is a super-absorbent polymer - meaning it can absorb 100 to 1000 times its mass in water. As an emollient, Sodium Polyacrylate helps soften and soothe skin. Emollients work by creating a barrier to trap moisture in. This helps keep your skin hydrated.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Â
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesÂ
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.
Studies have found adenosine may also help with wound healing.
In skincare products, Adenosine is usually derived from yeast.
Learn more about AdenosinePanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolHydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.
This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20Cholesterol is a class of organic molecules called lipids. It helps hydrate your skin and is essential to having a healthy skin barrier.
Our skin naturally contains cholesterol in the outermost layer. Besides cholesterol, it also contains ceramides and fatty acids. Cholesterol makes up about 1/4 of your skin's outer layer and barrier. Your skin barrier is responsible for keeping allergens and microbes out. Having a healthy skin barrier is also responsible for keeping your skin firm and plump.
Our bodies use cholestrol to create vitamin D, steroid hormones, and more.
Learn more about CholesterolSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronateTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateAcetyl Tetrapeptide-5 is a peptide that goes by another name, eyeseryl, due to claims that it can help reduce eye puffiness.
The manufacturer claims this ingredient reduces eye puffiness by:
An in-vivo study from the manufacturer found 95% of volunteers saw eye bag improvement by the end of the study.
Eye puffiness is caused by two major factors: fluid retention and fat.
Those with fluid retention may see improvement from using this ingredient. However, those with eye fat will need surgical intervention in order to get rid of puffiness.
Learn more about Acetyl Tetrapeptide-5You might know this ingredients as Matrixyl, a famous peptide.
Peptides are building blocks for protein. Palmitoyl Pentapeptide-4 consists of five amino acids. These amino acids include: 2 lysines, 2 threonines, and serine
This ingredients tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Thus, Matrixyl may help improve the look of wrinkles.
Read more about other common types of peptides here:
Learn more about Palmitoyl Pentapeptide-4This synthetic peptide is created from lysine, valine, and palmitic acid.
According to the manufacturer, in-vitro studies show tissue growth and collagen synthesis. Another in-vivo study found 60 volunteers saw a significant reduction in wrinkles after 84 days.
Due to its palmitic acid base, this peptide may not be fungal-acne safe.
Learn more about Palmitoyl Tripeptide-5Ingredient Ratings
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When to use
MediCube PDRN Pink Collagen Exosome Shot 2000 50 ingredients
Numbuzin 9+ NAD Bio Lifting-Sil Essence 120 ingredients
