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What's inside

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Show highlights for:

Water

Skin Conditioning

Homosalate

Skin Conditioning
UV Protection IconChemical UV Filter IconNon-Reef-Safe Icon

Ethylhexyl Methoxycinnamate

UV Absorber
0 / 0 UV Protection IconChemical UV Filter IconMay cause irritation IconNon-Reef-Safe Icon

Dipropylene Glycol

Humectant

Alcohol

Antimicrobial
Alcohol IconCan worsen Dry Skin IconMay worsen Eczema IconMay cause irritation IconMay worsen Rosacea Icon

Ethylhexyl Salicylate

UV Absorber
0 / 0 UV Protection IconChemical UV Filter IconNon-Reef-Safe Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin IconGood for Barrier Repair Icon

Butyl Methoxydibenzoylmethane

UV Absorber
UV Protection IconChemical UV Filter Icon

Niacinamide

Smoothing
Niacinamide IconHelps fight Acne IconHelps with Anti-Aging IconHelps brighten skin IconHelps reduce irritation IconGood for Oily Skin IconGood for Minimizing Pores IconHelps reduce Skin Redness IconGood for Scar Healing IconGood for Dark Spots IconGood for Skin Texture IconGood for Barrier Repair Icon

Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine

Skin Conditioning
UV Protection IconChemical UV Filter Icon

Dibutyl Adipate

Emollient

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconGood for Barrier Repair Icon

Octocrylene

UV Absorber
UV Protection IconChemical UV Filter IconMay worsen Eczema IconMay cause irritation IconNon-Reef-Safe Icon

Pentylene Glycol

Skin Conditioning
Good for Barrier Repair Icon

Curcuma Longa Root Extract

Masking
Fragrance Icon

Eclipta Prostrata Extract

Skin Conditioning
Helps reduce irritation Icon

Melia Azadirachta Flower Extract

Skin Conditioning

Moringa Oleifera Seed Oil

Emollient
Oil IconHelps hydrate Dry Skin IconHelps reduce irritation IconNot safe for Fungal Acne Icon

Corallina Officinalis Extract

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness Icon

Melia Azadirachta Extract

Skin Conditioning

Ocimum Basilicum Leaf Extract

Skin Conditioning

Hydrolyzed Collagen

Emollient
Helps with Anti-Aging IconHelps hydrate Dry Skin Icon

Canola Oil

Emollient
Oil IconBad for Acne Prone Skin IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon

Caesalpinia Spinosa Fruit Extract

Skin Protecting

Lactobacillus/Rye Flour Ferment

Skin Conditioning

Lactobacillus/Soymilk Ferment Filtrate

Skin Conditioning

Bacillus/Soybean Ferment Extract

Skin Conditioning

Chlorella Vulgaris Extract

Skin Conditioning

Kappaphycus Alvarezii Extract

Skin Conditioning

Daucus Carota Sativa Seed Oil

Emollient
Oil IconHelps hydrate Dry Skin IconHelps reduce irritation IconMay worsen Oily Skin Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps with Anti-Aging IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconGood for Barrier Repair Icon

Althaea Rosea Flower Extract

Skin Conditioning

Daucus Carota Sativa Root Extract

Skin Conditioning
Helps reduce irritation Icon

Helianthus Annuus Seed Oil

Emollient
0 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconHelps hydrate Dry Skin IconGood for Scar Healing IconGood for Barrier Repair Icon

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconHelps hydrate Dry Skin IconGood for Scar Healing Icon

Polymethylsilsesquioxane

Silicon Icon

Silica

Abrasive
Exfoliant IconGood for Oily Skin IconGood for Minimizing Pores Icon

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Emulsion Stabilising

Isohexadecane

Emollient

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

PEG-100 Stearate

Surfactant
0 / 0 Not safe for Fungal Acne Icon

Caprylyl Glycol

Emollient
Fatty Alcohol Icon

Acrylates Copolymer

Polysorbate 80

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Ethylhexylglycerin

Skin Conditioning

Adenosine

Skin Conditioning
Helps with Anti-Aging IconHelps reduce irritation IconGood for Scar Healing Icon

Sorbitan Oleate

Emulsifying
3 / 0 Bad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps with Anti-Aging IconHelps hydrate Dry Skin IconHelps brighten skin IconHelps reduce Skin Redness IconGood for Dark Spots IconGood for Barrier Repair Icon

Ceramide AP

Skin Conditioning
Ceramide IconHelps with Anti-Aging IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps reduce Skin Redness IconGood for Barrier Repair Icon

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Soluble Proteoglycan

Skin Conditioning

Sodium Dna

Skin Conditioning
Helps with Anti-Aging Icon

Beta-Carotene

Skin Conditioning

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant IconHelps brighten skin Icon

Hydrolyzed Sodium Hyaluronate

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Scar Healing Icon

Hydroxypropyltrimonium Hyaluronate

PEG-9 Diglycidyl Ether/Sodium Hyaluronate Crosspolymer

Skin Conditioning

Potassium Hyaluronate

Skin Conditioning

Sodium Acetylated Hyaluronate

Humectant
Hyaluronic Acid IconHelps with Anti-Aging Icon

Folic Acid

Skin Conditioning

Pantothenic Acid

Skin Conditioning

Propanediol

Solvent
Helps hydrate Dry Skin IconGood for Barrier Repair Icon

Pyridoxine

Skin Conditioning

Thiamine Hcl

Masking

Cyanocobalamin

Skin Conditioning

Hydroxydecyl Ubiquinone

Antioxidant
Antioxidant Icon

Riboflavin

Cosmetic Colorant

Dimethylsilanol Hyaluronate

Humectant
Hyaluronic Acid Icon

Disodium EDTA

Sodium Benzoate

Masking
Preservative Icon

Parfum

Masking
Synthetic Fragrance IconFragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Benzyl Salicylate

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Benzyl Benzoate

Antimicrobial
Fragrance IconMay cause irritation IconEU Allergen Icon

Butylphenyl Methylpropional

Perfuming
Synthetic Fragrance IconFragrance IconMay cause irritation IconEU Allergen Icon

Hexyl Cinnamal

Perfuming
Synthetic Fragrance IconFragrance IconMay cause irritation IconEU Allergen Icon

Hydroxycitronellal

Perfuming
Synthetic Fragrance IconFragrance IconMay worsen Eczema IconMay cause irritation IconMay worsen Rosacea IconEU Allergen Icon

Citronellol

Perfuming
Fragrance IconMay worsen Eczema IconMay cause irritation IconMay worsen Rosacea IconEU Allergen Icon

Melia Azadirachta Leaf Extract

Skin Conditioning

Water, Homosalate, Ethylhexyl Methoxycinnamate, Dipropylene Glycol, Alcohol, Ethylhexyl Salicylate, Butylene Glycol, Butyl Methoxydibenzoylmethane, Niacinamide, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Dibutyl Adipate, Glycerin, Octocrylene, Pentylene Glycol, Curcuma Longa Root Extract, Eclipta Prostrata Extract, Melia Azadirachta Flower Extract, Moringa Oleifera Seed Oil, Corallina Officinalis Extract, Melia Azadirachta Extract, Ocimum Basilicum Leaf Extract, Hydrolyzed Collagen, Canola Oil, Caesalpinia Spinosa Fruit Extract, Lactobacillus/Rye Flour Ferment, Lactobacillus/Soymilk Ferment Filtrate, Bacillus/Soybean Ferment Extract, Chlorella Vulgaris Extract, Kappaphycus Alvarezii Extract, Daucus Carota Sativa Seed Oil, Sodium Hyaluronate, Althaea Rosea Flower Extract, Daucus Carota Sativa Root Extract, Helianthus Annuus Seed Oil, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Polymethylsilsesquioxane, Silica, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isohexadecane, Glyceryl Stearate, PEG-100 Stearate, Caprylyl Glycol, Acrylates Copolymer, Polysorbate 80, Ethylhexylglycerin, Adenosine, Sorbitan Oleate, Tocopherol, Ceramide AP, 1,2-Hexanediol, Soluble Proteoglycan, Sodium Dna, Beta-Carotene, Tocopheryl Acetate, Hydrolyzed Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, PEG-9 Diglycidyl Ether/Sodium Hyaluronate Crosspolymer, Potassium Hyaluronate, Sodium Acetylated Hyaluronate, Folic Acid, Pantothenic Acid, Propanediol, Pyridoxine, Thiamine Hcl, Cyanocobalamin, Hydroxydecyl Ubiquinone, Riboflavin, Dimethylsilanol Hyaluronate, Disodium EDTA, Sodium Benzoate, Parfum, Benzyl Salicylate, Benzyl Benzoate, Butylphenyl Methylpropional, Hexyl Cinnamal, Hydroxycitronellal, Citronellol, Melia Azadirachta Leaf Extract

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Ā 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservativesĀ 
Skin Conditioning

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine
Skin Conditioning

This ingredient comes from the hollyhock flower. It has skin conditioning properties.

Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Learn more about Caprylyl Glycol
Skin Conditioning

Chlorella Vulgaris Extract comes from a green microalga. It is hydrating and contains antioxidants.

Studies also show Chlorella Vulgaris may help in rebuilding collagen and elastin. This ingredient is made up of lipids, carbohydrates, and chlorophyll.

Fun fact: This ingredient is commonly used as food additive in Japan.

Learn more about Chlorella Vulgaris Extract
Humectant, Moisturising, Skin Conditioning

Dimethylsilanol Hyaluronate is a type of hyaluronic acid.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Learn more about Disodium EDTA
Skin Conditioning

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Learn more about Ethylhexylglycerin
Humectant, Skin Conditioning, Skin Protecting

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Humectant, Moisturising, Skin Conditioning

Hyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.

Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.

The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

This is why the best HA serums blend the two sizes together so you get the best of both worlds.

The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.

A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.

These are some other common types of Hyaluronic Acid:

Learn more about Hyaluronic Acid
Emollient, Humectant, Skin Conditioning

Hydrolyzed Collagen is Collagen (usually sourced from fish, bovine, or porcine byproducts) that's been broken down into smaller peptides. This makes it water-soluble and easy to blend into formulations.

In a formula, it works mainly as a skin-conditioning and moisturizing agent.

The small peptides and amino acids (including Natural Moisturizing Factor components like Hydroxyproline, Serine, and Aspartic Acid) help the surface of the skin hold onto water, feel softer, and look temporarily plumper.

This ingredient also has mild film-forming and antioxidant properties with research showing the antioxidant effect is stronger the lower the molecular weight of the peptides.

It's worth being realistic here:

Topically applied Hydrolyzed Collagen conditions the upper layers of skin rather than rebuilding the structural collagen deep in your dermis (the wrinkle-and-firmness benefits people associate with Collagen mostly come from oral supplements in studies, not topicals).

However, recent lab and skin-model work on Hydrolyzed Fish Collagen has shown promising effects on cell viability and wound healing when used as an active.

Typical concentrations range from 0.2-2%, but the percentage can go much higher in rinse-off or hair products (sometimes even above 50%).

Clinical studies on this ingredient showed no irritation, sensitization, or phototoxicity.

If you are looking for vegan collagen, it usually goes by a different INCI name like hydrolyzed soy protein. Vegan collagen is derived from yeast, bacteria, or plant sources.

The results are varied.

A study from 2021 found hydrolyzed collagen increased elasticity and improved wrinkles in 1,125 participants between age 20 and 70. Another study found increased skin thickness in participants between the ages of 45 to 59.

However, It is difficult to prove that oral collagen will end up working on your skin. Many of the studies using hydrolyzed collagen also add several vitamins and nutrients into the test mixture as well.

Further studies are needed at this time.

Learn more about Hydrolyzed Collagen
Humectant, Skin Conditioning

Hydrolyzed Hyaluronic Acid is hyaluronic acid (HA) that is broken down into lower molecular weight fragments.

It's a humectant that pulls and holds water in the skin to help with hydration, plumpness, and reduce transepidermal water loss.

Because hydrolyzed hyaluronic acid is smaller in size, it can slip past your outermost layer of skin more easily than full-sized HA.

Most formulations will combine all sizes to get the best of both worlds.

Typical usage levels range from 0.01-1%. Any percentage higher than 2% might become goopy and tacky.

Learn more about Hydrolyzed Hyaluronic Acid
Skin Conditioning

This ingredient is created by putting sodium hyaluronate through hydrolysis.

You might know this as 'mini' or 'ultra low-molecular weight' hyaluronic acid. The small molecule size means it is able to travel deeper in the skin.

According to studies, low molecular-weight hyaluronic acid can:

One study from 2011 found ultra-low weight HA to show pro-inflammatory properties. Another study from 2022 found it to downregulate UV-B induced inflammation.

Hydrolysis is a process of changing a molecule using water or enzymes.

This ingredient is water-soluble.

Learn more about Hydrolyzed Sodium Hyaluronate

This form of hyaluronic acid is produced through fermentation.

According to a manufacturer, it has a positive charge by ionic binding to help moisturize and give hair a smooth feel. This is why you'll find this ingredient in shampoos and body washes.

Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide
Masking, Perfuming

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of ā€œFRAGRANCEā€ or ā€œPARFUMā€ according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Learn more about Parfum

We don't have a description for PEG-9 Diglycidyl Ether/Sodium Hyaluronate Crosspolymer yet.

Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.

This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.

Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.

Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.

Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.

Learn more about Pentylene Glycol
Skin Conditioning

Potassium hyaluronate (PH) is a salt form of hyaluronic acid and has similar skin hydrating benefits.

Similar to hyaluronic acid, PH is able to draw and hold moisture to your skin. This helps keep skin soft and hydrated.

Fun fact: PH is used in eye drops and injectable treatments for joint disorders. It has lubricating and tissue-repair properties.

Learn more about Potassium Hyaluronate
Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.Ā 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol

Sodium Acetylated Hyaluronate is a type of Hyaluronic Acid.

Hyaluronic Acids help moisturize, soothe, and protect the skin.

Read about common types of Hyaluronic Acid here:

Learn more about Sodium Acetylated Hyaluronate
Masking, Preservative

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Learn more about Sodium Benzoate
Skin Conditioning

Sodium DNA is an emerging anti-aging ingredient.

It is created by taking deoxyribonucleic acid (DNA) and purifying it with sodium hydroxide.

The DNA is extracted from several different animal sources, including: calf thymus, the gonadic tissue of a male sturgeon, or herring / salmon sperm.

You have probably seen this ingredient in anti-aging skincare. But what is it?

DNA is composed of nucleotides, or chemical building blocks. Nucleotides include adenine (A), thymine (T), guanine (G), and cytosine (C). Talk about a flashback to biology! Nucleosides are formed from these nucleotides.

The science behind Sodium DNA is based on an ingredient called Polydeoxyribonucleotide or PDRN.

PDRN are DNA fragments mainly extracted from the sperm cells of trout or salmon. Meaning, PDRN can be derived from Sodium DNA.

PDRN consists of chains of nucleotides and nucleosides mentioned above. They can range anywhere from 80 - 2000 pairs.

Studies show PDRN has the following properties:

Most of the research on PDRN has been done using injectable forms. That’s important, because PDRN is a large molecule and doesn’t absorb well through the skin. So if you’re applying it topically, the effects are likely to be much milder.

Still, topical Sodium DNA is emerging as a trendy anti-aging ingredient. It’s generally well-tolerated and offers good biocompatibility with human skin, making it a low-risk addition to most routines.

Further studies are needed to truly confirm this ingredients anti-aging ability (Remember, retinol has decades of research!).

Sodium DNA may be sourced from fish, animal tissue, or plants. Since this isn’t always disclosed, we recommend asking the brand directly if the ingredient’s origin is important to you.

Learn more about Sodium Dna
Humectant, Skin Conditioning

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Learn more about Sodium Hyaluronate
Skin Conditioning

Soluble Proteoglycan is the name used for water-soluble proteoglycans, or large ā€œgel-likeā€ skin matrix molecules. These molecules help skin hold onto water and support the structure around cells.

In a small 4-week clinical study, people with mild atopic dermatitis, dry, and eczema-prone skin found using a daily emollient (soluble proteoglycan + hyaluronic acid + hydrolyzed collagen) significantly improved skin hydration, transepidermal water loss (TEWL), and itch.

Research also suggests that proteoglycans from sources like salmon nasal cartilage can "talk" to skin cells and encourage them to stay healthy by supporting the cells that maintain the skin's structure.

Other studies show proteoglycans may help skin recover from damage from things like UV exposure.

Learn more about Soluble Proteoglycan
Antioxidant, Masking, Skin Conditioning

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Learn more about Tocopherol
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Learn more about Water

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