Versus

Isntree TW-Real Bifida Ampoule Versus AXIS - Y Biome Radiating Intensified Essence

Ampoule
Essence
Korean Brand South Korea
Korean Brand South Korea

Updated on September 05, 2024

Overview

What they are

These products are both cruelty-free and reef safe . They have a total of 12 ingredients in common

Cool Features

They both contain ceramides and niacinamide

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, parabens or sulfates

What's Inside

They both contain fragrances, oils and silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
TW-Real Bifida Ampoule

Water

Skin Conditioning

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Dipropylene Glycol

Masking

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Cyclopentasiloxane

Emollient
Silicon Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Hydrogenated Polydecene

Emollient

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Dimethicone

Emollient
1 / 0 Silicon Icon

Pentaerythrityl Tetraethylhexanoate

Emollient
Helps hydrate Dry Skin Icon

Bifida Ferment Lysate

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Arachidyl Alcohol

Emollient

Butyrospermum Parkii Butter

Skin Conditioning
Helps hydrate Dry Skin IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

C12-16 Alcohols

Emollient

Polyglyceryl-2 Stearate

Emulsifying
Not safe for Fungal Acne Icon

Dimethicone/Vinyl Dimethicone Crosspolymer

Skin Conditioning

Behenyl Alcohol

Emollient
Fatty Alcohol Icon

Erythritol

Humectant
Helps hydrate Dry Skin Icon

Polysorbate 60

Emulsifying
Not safe for Fungal Acne Icon

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Hydrogenated Lecithin

Emulsifying
Helps hydrate Dry Skin Icon

Stearyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Arachidyl Glucoside

Emulsifying

Palmitic Acid

Emollient
2 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Carbomer

Emulsion Stabilising
1 / 0

Tromethamine

Buffering

Illicium Verum Fruit Extract

Perfuming
Fragrance Icon

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Emulsion Stabilising

Mangifera Indica Seed Butter

Skin Conditioning
Not safe for Fungal Acne Icon

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Emulsion Stabilising

Isohexadecane

Emollient

Persea Gratissima Oil

Skin Conditioning
0-3 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Hydroxyethylcellulose

Emulsion Stabilising

Scutellaria Baicalensis Root Extract

Astringent

Adenosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing Icon

Polysorbate 80

Emulsifying
0 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Disodium EDTA

Hydrogenated Vegetable Oil

Emollient
3 / 0 Oil IconHelps hydrate Dry Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

3-O-Ethyl Ascorbic Acid

Skin Conditioning
Vitamin C IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores Icon

Sorbitan Oleate

Emulsifying
3 / 0 Bad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Glucose

Humectant
Helps hydrate Dry Skin Icon

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Daucus Carota Sativa Root Extract

Skin Conditioning
Helps reduce irritation Icon

Caprylyl Glycol

Emollient

Sodium Phosphate

Buffering

Pentylene Glycol

Skin Conditioning

Deoxyphytantriyl Palmitamide Mea

Skin Conditioning

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Ethylhexylglycerin

Skin Conditioning

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

Lecithin

Emollient
Helps hydrate Dry Skin Icon

Phosphatidylcholine

Emulsifying

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging Icon

Sh-Oligopeptide-2

Skin Conditioning
Peptide Icon

Sh-Polypeptide-1

Skin Conditioning
Peptide Icon

Astaxanthin

Skin Conditioning
Helps reduce irritation IconHelps with Anti-Aging Icon

Sh-Oligopeptide-1

Skin Conditioning
Peptide IconHelps with Anti-Aging IconGood for Scar Healing Icon
Biome Radiating Intensified Essence

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Masking, Solvent

Dipropylene Glycol is a synthetically created stabilizer and solvent. It is a part of the glycol class in the alcohol family.

Dipropylene Glycol helps dissolve and evenly distribute ingredients. It also helps decrease viscosity and thin out texture.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Learn more about Dipropylene Glycol
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide
Skin Conditioning

Bifida Ferment Lysate is derived from the fermentation of Bifida bacteria (often with dairy). It is a probiotic and helps to strengthen our skin's microbiome.

Having a healthy microbiome helps protect our skin against infection. It also helps our skin stay hydrated and healthy.

Studies also show this ingredient to be a promising soothing ingredient for sensitive skin.

Learn more about Bifida Ferment Lysate
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Emulsifying, Skin Conditioning

Hydrogenated Lecithin is created from the hydrogenation of lecithin (a group of phospholipids). Hydrogenation is a chemical reaction between hydrogen and another element.

This ingredient is an emollient and emulsifier. As an emollient, it helps soften skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Buffering, Masking

Tromethamine helps balance the pH and improve the texture of a product. It is synthetically created.

As an emulsifier, Tromethamine prevents oil and water ingredients from separating. This helps stabilize the product and elongate a product's shelf life. Tromethamine also makes a product thicker.

Tromethamine helps balance the pH level of a product. Normal pH level of skin is slightly acidic (~4.75-5.5). The acidity of our skin is maintained by our glands and skin biome. Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.

Oral Tromethanmine is an anti-inflammatory drug but plays the role of masking, adding fragrance, and/or balancing pH in skincare.

1,3-Propanediol, 2-amino-2-(hydroxymethyl)-

Learn more about Tromethamine
Skin Conditioning

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine
Skin Conditioning

Ceramide NP is a type of ceramide.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here: Ceramide AP Ceramide EOP

Learn more about Ceramide NP
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

When to use

20 Routines
35% use in am
65% use in pm
85% use every day
9 Routines
33% use in am
67% use in pm
89% use every day

Reviews

Here's what our community thinks

Isntree TW-Real Bifida Ampoule 62 ingredients

2.7 /5
from 3 ratings
Absorbs Well (2) Broke Me Out (1) Doesn't Work (1)
nikisadaghiani's avatar

Niki Sdni

6 months ago
Review

I haven’t used a full bottle only tried for few days, still didn’t like it that much, what does it suppose to do? Not a bad product, but many many better alternatives are available

#expensive
#hydrating
#absorbs well
#no scent
Suzamazen's avatar

Suzanne S.

1 month ago
Review

I absolutely loved the original version of this serum. It helped my oily, cystic-acne prone skin retain moisture and let my skin handle harsher products like acid exfoliants and benzoyl peroxide without completely stripping my skin. This new formulation is a list of the worst ingredients for oily and acne prone skin. Using the SkinSort match score, the original formulation was a 88% match for Show more

#broke me out

AXIS - Y Biome Radiating Intensified Essence 37 ingredients

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