Centellian24 Madeca Micro Startoc Serum

Centellian24 Madeca Micro Startoc Serum

This calming serum is formulated around Niacinamide and Centella Asiatica Leaf Extract to calm redness and strengthen the skin barrier.

Worth noting

Contains EU-listed fragrance allergens, including Rosa Damascena Flower Oil and Lavandula Angustifolia Oil.

We independently verify ingredients, backed by peer-reviewed research. Suggest an update.

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What's inside

Ingredients List

26
39
12

Niacinamide

Smoothing
Niacinamide IconHelps fight Acne IconHelps with Anti-Aging IconHelps brighten skin IconHelps reduce irritation IconGood for Oily Skin IconGood for Minimizing Pores IconHelps reduce Skin Redness IconGood for Scar Healing IconGood for Dark Spots IconGood for Skin Texture IconGood for Barrier Repair Icon

Rosa Damascena Flower Oil

Masking
Oil IconEssential Oil IconFragrance IconMay cause irritation IconMay worsen Perioral Dermatitis IconMay worsen Psoriasis IconEU Allergen Icon

Dimethicone

Emollient
1 / 0 Silicon IconGood for Scar Healing Icon

Disodium EDTA

Lavandula Angustifolia Oil

Masking
Oil IconEssential Oil IconFragrance IconMay cause irritation IconMay worsen Perioral Dermatitis IconMay worsen Psoriasis IconEU Allergen Icon

Lavandula Angustifolia Extract

Skin Conditioning
May cause irritation IconEU Allergen Icon

Rosmarinus Officinalis Extract

Antimicrobial

Magnesium Chloride

Maltodextrin

Absorbent
Helps hydrate Dry Skin Icon

Methyl Gluceth-10

Emulsifying

Anhydroxylitol

Humectant
Helps hydrate Dry Skin Icon

Ficus Carica Fruit Extract

Humectant
Helps hydrate Dry Skin Icon

Citrus Aurantium Bergamia Fruit Oil

Masking
Oil IconEssential Oil IconFragrance IconMay worsen Perioral Dermatitis IconMay worsen Psoriasis Icon

Behenyl Alcohol

Emollient
Fatty Alcohol Icon

Centella Asiatica Leaf Extract

Skin Conditioning
Helps with Anti-Aging IconHelps reduce irritation IconHelps reduce Skin Redness IconGood for Barrier Repair Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin IconGood for Barrier Repair Icon

Bisabolol

Antioxidant
Antioxidant IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps reduce Skin Redness IconGood for Scar Healing IconGood for Barrier Repair Icon

Saccharum Officinarum Extract

Moisturising

Punica Granatum Fruit Extract

Antioxidant
Antioxidant IconHelps reduce irritation IconGood for Dark Spots Icon

Thymus Vulgaris Extract

Perfuming
Fragrance Icon

Ceteareth-20

Cleansing
2 / 3

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconCoconut Derived IconBad for Acne Prone Skin IconMay worsen Seborrheic Dermatitis IconMay worsen Keratosis Pilaris IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon

Pelargonium Graveolens Flower Oil

Masking
Oil IconEssential Oil IconFragrance IconMay cause irritation IconMay worsen Perioral Dermatitis IconMay worsen Psoriasis IconEU Allergen Icon

Sodium Polyacrylate

Absorbent
Helps hydrate Dry Skin Icon

Prunus Amygdalus Dulcis Seed Extract

Skin Conditioning

Stearic Acid

Cleansing
2-3 / 0 Helps hydrate Dry Skin IconMay worsen Seborrheic Dermatitis IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon

Silica

Abrasive
Exfoliant IconGood for Oily Skin IconGood for Minimizing Pores Icon

Artemisia Absinthium Extract

Skin Conditioning

Adenosine

Skin Conditioning
Helps with Anti-Aging IconHelps hydrate Dry Skin IconHelps reduce irritation Icon

Asiaticoside

Antioxidant
Synthetic Fragrance IconFragrance IconAntioxidant IconHelps with Anti-Aging IconHelps reduce irritation IconHelps reduce Skin Redness IconGood for Scar Healing IconGood for Skin Texture IconGood for Barrier Repair Icon

Asiatic Acid

Skin Conditioning
Helps with Anti-Aging IconHelps reduce Skin Redness IconGood for Scar Healing IconGood for Barrier Repair Icon

Cedrus Atlantica Bark Oil

Masking
Oil IconEssential Oil IconFragrance IconMay cause irritation IconMay worsen Perioral Dermatitis IconMay worsen Psoriasis IconEU Allergen Icon

Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer

Emulsion Stabilising

Morus Alba Fruit Extract

Antioxidant
Antioxidant Icon

Citrus Aurantium Dulcis Oil

Masking
Oil Icon

Octanediol

Olea Europaea Fruit Oil

Masking
0-2 / 0 Oil IconFragrance IconHelps hydrate Dry Skin IconMay worsen Seborrheic Dermatitis IconNot safe for Fungal Acne Icon

Citrus Grandis Peel Oil

Masking
Oil IconEssential Oil IconFragrance IconCan worsen Dry Skin IconMay worsen Perioral Dermatitis IconMay worsen Psoriasis IconMay worsen Keratosis Pilaris Icon

Ginkgo Biloba Nut Extract

Skin Conditioning

Inulin Lauryl Carbamate

Emulsion Stabilising

Isocetyl Stearate

Emollient
0-1 / 0 Bad for Acne Prone Skin IconMay worsen Seborrheic Dermatitis IconMay worsen Keratosis Pilaris IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon

Cananga Odorata Flower Oil

Masking
Oil IconEssential Oil IconFragrance IconMay worsen Eczema IconMay cause irritation IconMay worsen Perioral Dermatitis IconMay worsen Psoriasis IconEU Allergen Icon

Xylitol

Humectant
Helps hydrate Dry Skin IconGood for Barrier Repair Icon

Xylitylglucoside

Humectant
Helps hydrate Dry Skin Icon

Xanthan Gum

Emulsifying

Rose Flower Oil

Masking
Oil IconMay cause irritation IconEU Allergen Icon

Jasminum Officinale Oil

Masking
Oil IconEssential Oil IconFragrance IconMay cause irritation IconMay worsen Perioral Dermatitis IconMay worsen Psoriasis IconEU Allergen Icon

Chondrus Crispus Extract

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness Icon

Caprylic/Capric Triglyceride

Masking
Coconut Derived IconFragrance IconHelps hydrate Dry Skin IconGood for Barrier Repair Icon

Copaifera Officinalis Resin

Masking

Tromethamine

Buffering

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce irritation IconHelps reduce Skin Redness IconGood for Scar Healing IconGood for Barrier Repair Icon

Palmitoyl Tripeptide-5

Skin Conditioning
Peptide IconHelps with Anti-Aging IconGood for Skin Texture Icon

Palmitic Acid

Emollient
2 / 0 Helps hydrate Dry Skin IconMay worsen Seborrheic Dermatitis IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon

Phenoxyethanol

Preservative
Preservative Icon

Pentylene Glycol

Skin Conditioning
Good for Barrier Repair Icon

Polyglyceryl-10 Stearate

Skin Conditioning
May worsen Seborrheic Dermatitis IconNot safe for Fungal Acne Icon

Propanediol

Solvent
Helps hydrate Dry Skin IconGood for Barrier Repair Icon

PEG-14m

Emulsion Stabilising

Phytosteryl Macadamiate

Skin Conditioning
May worsen Seborrheic Dermatitis IconNot safe for Fungal Acne Icon

Hydrogenated Lecithin

Emulsifying
Helps hydrate Dry Skin IconGood for Barrier Repair Icon

Hydrolyzed Vegetable Protein

Skin Conditioning

Helianthus Annuus Seed Oil

Emollient
0 / 0 Oil IconHelps hydrate Dry Skin IconMay worsen Seborrheic Dermatitis IconNot safe for Fungal Acne Icon

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Yeast Extract

Skin Conditioning

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps with Anti-Aging IconHelps hydrate Dry Skin IconGood for Scar Healing Icon

Ferula Galbaniflua Resin Oil

Antimicrobial
Oil IconEssential Oil IconFragrance IconMay worsen Perioral Dermatitis IconMay worsen Psoriasis Icon

Limonia Acidissima Extract

Skin Conditioning

Origanum Vulgare Flower/Leaf/Stem Extract

Skin Conditioning

Ceramide NP

Skin Conditioning
Ceramide IconHelps with Anti-Aging IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps reduce Skin Redness IconGood for Barrier Repair Icon

Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate

Skin Conditioning

Thuja Occidentalis Leaf Oil

Masking
Oil IconEssential Oil IconFragrance IconMay worsen Perioral Dermatitis IconMay worsen Psoriasis Icon

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Skin Conditioning
Peptide IconHelps with Anti-Aging Icon

Madecassic Acid

Skin Conditioning
Helps with Anti-Aging IconHelps reduce irritation IconHelps reduce Skin Redness IconGood for Scar Healing IconGood for Barrier Repair Icon

Centella Asiatica Extract

Cleansing
Helps with Anti-Aging IconHelps reduce irritation IconHelps reduce Skin Redness IconGood for Scar Healing IconGood for Skin Texture IconGood for Barrier Repair Icon

PEG-60 Hydrogenated Castor Oil

Emulsifying
Oil IconMay worsen Seborrheic Dermatitis IconNot safe for Fungal Acne Icon

Niacinamide, Rosa Damascena Flower Oil, Dimethicone, Disodium EDTA, Lavandula Angustifolia Oil, Lavandula Angustifolia Extract, Rosmarinus Officinalis Extract, Magnesium Chloride, Maltodextrin, Methyl Gluceth-10, Anhydroxylitol, Ficus Carica Fruit Extract, Citrus Aurantium Bergamia Fruit Oil, Behenyl Alcohol, Centella Asiatica Leaf Extract, Butylene Glycol, Bisabolol, Saccharum Officinarum Extract, Punica Granatum Fruit Extract, Thymus Vulgaris Extract, Ceteareth-20, Cetearyl Alcohol, Pelargonium Graveolens Flower Oil, Sodium Polyacrylate, Prunus Amygdalus Dulcis Seed Extract, Stearic Acid, Silica, Artemisia Absinthium Extract, Adenosine, Asiaticoside, Asiatic Acid, Cedrus Atlantica Bark Oil, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, Morus Alba Fruit Extract, Citrus Aurantium Dulcis Oil, Octanediol, Olea Europaea Fruit Oil, Citrus Grandis Peel Oil, Ginkgo Biloba Nut Extract, Inulin Lauryl Carbamate, Isocetyl Stearate, Cananga Odorata Flower Oil, Xylitol, Xylitylglucoside, Xanthan Gum, Rose Flower Oil, Jasminum Officinale Oil, Chondrus Crispus Extract, Caprylic/Capric Triglyceride, Copaifera Officinalis Resin, Tromethamine, Panthenol, Palmitoyl Tripeptide-5, Palmitic Acid, Phenoxyethanol, Pentylene Glycol, Polyglyceryl-10 Stearate, Propanediol, PEG-14m, Phytosteryl Macadamiate, Hydrogenated Lecithin, Hydrolyzed Vegetable Protein, Helianthus Annuus Seed Oil, 1,2-Hexanediol, Yeast Extract, Hydrolyzed Hyaluronic Acid, Ferula Galbaniflua Resin Oil, Limonia Acidissima Extract, Origanum Vulgare Flower/Leaf/Stem Extract, Ceramide NP, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Thuja Occidentalis Leaf Oil, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Madecassic Acid, Centella Asiatica Extract, PEG-60 Hydrogenated Castor Oil

Key Ingredients

Benefits

Concerns

Ingredients Explained

Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide
Masking, Perfuming, Skin Conditioning

Rosa Damascena Flower Oil is an essential oil made from the Damask Rose. It is often used as a fragrance in cosmetics.

Rose Oil has antibacterial and antioxidant properties due to its terpene, glycoside, flavonoid, anthocyanin, and Vitamin C content.

Other major parts of Rose Oil include citronellol and geraniol. Both of these are known EU allergens and cause contact-allergies.

The downsides of this ingredient outweight the positives.

Learn more about Rosa Damascena Flower Oil
Emollient, Skin Conditioning, Skin Protecting

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Learn more about Dimethicone

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Learn more about Disodium EDTA
Masking, Perfuming, Tonic

Lavandula Angustifolia Oil is more commonly known as lavender essential oil. It is considered a fragrancing ingredient.

Lavender imparts a famous scent. While the smell is lovely, this ingredient and may sensitize skin in topical products. This is because about 85% of the oil is made up of linalool and linalyl acetate.

When exposed to air, these two compounds become strong allergens. This ingredient exhibits cytotoxicity at low concentrations; amounts of 0.25% have been shown to damage skin cells.

A study from Japan found this ingredient caused lavender sensitivity after widespread exposure.

Lavender essential oil has some antimicrobial, antibacterial, and anti-inflammatory properties. However, the cons of this ingredient may outweight the pros.

More research is needed to confirm lavender essential oil's effects when used in aromatherapy.

Lavandula Angustifolia is known as the English Lavender and famous for creating purple fields in Provence, France.

Learn more about Lavandula Angustifolia Oil
Skin Conditioning

Lavandula Angustifolia Extract comes from the flowers and leaves of the lavender plant. It's mostly used in skincare for its scent plus a bit of skin conditioning properties.

Lab research credits it with soothing, antioxidant, and wound-supporting effects. This is largely thanks to a compound called rosmarinic acid.

Rosmarinic acid has been shown to calm inflammation signaling in skin cells (the same pathways that flare up in conditions like eczema and psoriasis). It also has real antimicrobial and antifungal activity in test-tube studies.

This ingredient is typically used in low concentrations (generally well under 1%) where it acts as a light fragrance + mild skin soother extract.

The main thing to know is that lavender contains two naturally fragrant molecules: Linalool and Linalyl Acetate. Some people's skin does perfectly fine with fragrance while others don't.

Just be sure to patch test if you have reactive skin or known plant allergies.

Linalool and Linalyl Acetate are gentle when fresh but oxidize into compounds that can cause allergic contact dermatitis when exposed to air. Patch-test studies of patients already being investigated for skin allergies found about 5-7% of patients had reactions to oxidized linalool, and 2.8% of patients reacted to oxidized lavender oil.

Learn more about Lavandula Angustifolia Extract
Antimicrobial, Refreshing, Tonic

Rosemary extract has antioxidant, anti-inflammatory, anti-bacterial, and astringent properties.

This ingredient has a natural fragrance due its small component of rosemary oil. The antioxidant properties from its rosmarinic acid, flavone, and phenolic acids.

Magnesium chloride is a mineral salt made from magnesium and chloride. It is mainly used to control product stability and texture in cosmetics.

This ingredient can also play a role in soothing the skin and supporting normal skin function.

Magnesium chloride is water-soluble, generally well tolerated, and does not act as a strong “active” ingredient on its own.

Learn more about Magnesium Chloride
Absorbent, Emulsion Stabilising, Skin Conditioning

Maltodextrin is a plant-derived carbohydrate made by breaking down starch (usually from corn, potato, or rice). In cosmetic formulas, it's a multitasking absorbent, emulsion stabilizer, and skin conditioner.

This ingredient is mostly used to stabilize emulsions and improve the powdery, non-greasy feel of products (like dry shampoos).

Safety-wise, this ingredient is pretty solid; it's even recognized as a food additive. Both animal and clinical studies found no adverse effects at the levels used in cosmetics.

Industry data shows this ingredient is used up to 45.7% in spray products and up to 33% in powder products.

Learn more about Maltodextrin
Emulsifying, Humectant, Moisturising

We don't have a description for Methyl Gluceth-10 yet.

Humectant, Skin Conditioning

This ingredient is created from dehydrating xylitol in acidic conditions. Xylitol is a famous sugar and humectant.

Much like its predecessor, anhydroxylitol is a humectant. Humectants attract and hold water to moisturize the skin.

This ingredient is most commonly found in a popular trio called Aquaxyl. Aquaxyl is made up of anhydroxylitol (24 - 34%), xylitylglucoside (35 - 50%), and xylitol (5 - 15%).

According to a manufacturer, Aquaxyl is known for a 3-D hydration concept and an anti-dehydration shield to reinforce the outer layer of skin.

This ingredient is often derived from plants such as wood and sugarcane.

Learn more about Anhydroxylitol

Ficus Carica Fruit Extract comes from the fruit known as the fig. Figs are rich in antioxidants and helps hydrate the skin.

Figs also contain fatty acids and Vitamins A, B1, and B2.

As a humectant, figs are able to draw moisture from the air to your skin. This helps keep your skin hydrated.

Learn more about Ficus Carica Fruit Extract

Citrus Aurantium Bergamia Fruit Oil is the oil from the bergamot orange and is primarily used as a fragrance. It has a "fresh" and "bright orange" scent.

The main aroma compounds found in this ingredient are limonene (~27-52%), linalool (~2-22%), and linalyl acetate (~27-40%). These are known EU fragrance allergens.

The term 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term. For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance.

When used topically, Citrus Aurantium Bergamia Fruit Oil is a photosensitizer due to the furanocoumarin content. Furanocoumarins absorb UV-A and cause phytophotodermatitis; this can look like redness, blistering, and lasting brown pigmentation on sun-exposed skin.

Due to this, this ingredient is capped at 0.4% in leave-on products applied to sun exposed skin.

Many modern formulas used a "furanocoumarin-free" version that sidesteps the phototoxicity issue, but still contains the fragrance allergens.

Learn more about Citrus Aurantium Bergamia Fruit Oil
Emollient, Emulsion Stabilising

Behenyl Alcohol is a type of fatty alcohol (these are different from the drying, solvent alcohols).

Fatty Alcohols have hydrating properties and are most often used as an emollient or to thicken a product. They are usually derived from natural fats and oils; behenyl alcohol is derived from the fats of vegetable oils.

Emollients help keep your skin soft and hydrated by creating a film that traps moisture in.

In 2000, Behenyl Alcohol was approved by the US as medicine to reduce the duration of cold sores.

Learn more about Behenyl Alcohol
Skin Conditioning

Centella Asiatica Leaf Extract comes from the leaves of an herb plant native to Southeast Asia. Centella Asiatica is rich in antioxidants and amino acids. It can help reduce irritation and soothe the skin.

Many active components found in centella asiatica, such as Madecassic Acid and Asiaticoside, encourage the skin to naturally produce hyaluronic acid. This helps keep our skin hydrated. Many of these components also show antioxidant activity and may help reduce the signs of aging.

Research shows centella asiatica can help increase Type I collagen production by increasing fibroblast production. Fibroblast helps form connective tissue.

The combination of all these properties makes centella asiatica leaf extract effective at soothing the skin.

Other components of centella asiatica leaf extract include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.

Recent studies found madecassoside may help prevent damage from UV rays by preventing UV-induced inflammation. Further research is needed.

This plant has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Learn more about Centella Asiatica Leaf Extract
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Antioxidant, Masking, Skin Conditioning

Bisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient.

It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation.

A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin.

In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum.

You'll likely see use concentrations quite low, usually 0.1-0.2%.

Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin.

Learn more about Bisabolol
Moisturising, Skin Conditioning

This ingredient is also called sugarcane extract. It is a moisturizing humectant and has skin soothing properties.

Similar to hyaluronic acid, sugarcane can attract moisture to your skin.

Glycolic acid is a derivative of sugarcane. While glycolic acid is an AHA with exfoliating properties, sugarcane is not an AHA.

A study from 2021 found the compounds in sugarcane extract to have antioxidant, antimicrobial, and anti-inflammatory activity. The study also suggests these compounds can inhibit skin ageing enzymes and promote collagen synthesis.

Learn more about Saccharum Officinarum Extract
Antioxidant, Skin Conditioning

You might know this ingredient as pomegranate fruit. It has been shown to have antioxidant, skin soothing and anti-aging benefits.

Pomegranates are rich in antioxidant compounds such as polyphenolic compounds such as ellagic acid, phenolic acids, anthocyanins, and flavonoids.

Both in-vivo and in-vitro studies show pomegranate fruit helps with:

These benefits offer skin anti-aging and skin soothing benefits.

Fun fact: The name pomegranate comes from two latin words: "pome" or apple, and "granate" or "many seeded".

Pomegranate flower extract is often confused for pomegranate fruit extract, but comes from the flowers of the tree.

Learn more about Punica Granatum Fruit Extract
Perfuming, Skin Conditioning

This ingredient comes form the common thyme plant. It has skin conditioning and perfuming ingredients.

In-vitro studies show strong antioxidant activity due to the high phenolic content of thyme.

Studies also demonstrate it has antimicrobial activity against acne-related bacteria. A 2017 study found this extract exhibited anti-inflammatory effects.

However, this ingredient does have sensitization potential due to its terpene content. Terpenes are among the most common causes of contact dermatitis.

This is kind of a double-edged sword situation where the same compounds that give it antimicrobial power can also irritate reactive skin.

Learn more about Thymus Vulgaris Extract
Cleansing, Emulsifying, Surfactant

Ceteareth-20 is an emulsifier and surfactant made by reacting cetearyl alcohol with 20 moles of ethylene oxide.

This gives it both oil and water-loving properties that makes it an effect emulsifier; it's really great at pulling oil droplets into water to create a stable, creamy, and easy-to-spread base.

Typical use ranges from 0.5-30%. Most leave-on products are in the 1-10% zone.

The 20 ethylene oxide units is well above the PEG-10 threshold and therefore not a food source for Malassezia (it's fungal acne safe).

This ingredient has a comedogenic rating of 2 and an irritancy rating of 3. These numbers come from testing the raw ingredient on rabbit ears and doesn't reflect how it will behave in a finished product.

In practice, this ingredient is a well-tolerated ingredient. The ratings reflect cautious lab conditions and not real-world use. Just be sure to patch test any formulas you feel unsure about.

Learn more about Ceteareth-20
Emollient, Emulsifying, Emulsion Stabilising

Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.

Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.

It plays several roles in a formula:

Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.

Multiple assessments have found it to be non-irritating and non-sensitizing to most people.

However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.

Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.

Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.

Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.

This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.

A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.

Learn more about Cetearyl Alcohol

Pelargonium Graveolens Flower Oil is the pressed oil of the Rose Geranium plant. It is volatile, meaning it evaporates off the skin.

Fragrant components of Rose Geranium include citronellol and geraniol. These may cause allergies and skin-sensitivity. We recommend speaking with a professional if you have any concerns.

The scent of Rose Geranium closely resembles traditional roses.

Learn more about Pelargonium Graveolens Flower Oil
Absorbent, Emollient, Emulsion Stabilising

Sodium Polyacrylate is the sodium salt of polyacrylic acid. It is used as an absorber, emollient, and stabilizer.

This ingredient is a super-absorbent polymer - meaning it can absorb 100 to 1000 times its mass in water. As an emollient, Sodium Polyacrylate helps soften and soothe skin. Emollients work by creating a barrier to trap moisture in. This helps keep your skin hydrated.

Prunus Amygdalus Dulcis Seed Extract is the extract from dried sweet almond seeds.

Almonds contain healthy fats, vitamins, and minerals. It is a rich source of Vitamin E, a great antioxidant and skin conditioning ingredient. Sweet almond oil contains fatty acids such as linolenic acid and triglycerides.

Prunus amygdalus dulcis is native to Iran.

Learn more about Prunus Amygdalus Dulcis Seed Extract
Cleansing, Emulsifying, Emulsion Stabilising

Stearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.

In cosmetics, it is a multitasker:

Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.

Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.

Learn more about Stearic Acid
Abrasive, Absorbent

Silica, also known as silicon dioxide, is a naturally occurring mineral. It is used as a fine, spherical, and porous powder in cosmetics.

Though it has exfoliant properties, the function of silica varies depending on the product.

The unique structure of silica enhances the spreadability and adds smoothness, making it a great texture enhancer.

It is also used as an active carrier, emulsifier, and mattifier due to its ability to absorb excess oil.

In some products, tiny microneedles called spicules are made from silica or hydrolyzed sponge. When you rub them in, they lightly polish away dead skin layers and enhance the penetration of active ingredients.

Learn more about Silica
Skin Conditioning

We don't have a description for Artemisia Absinthium Extract yet.

Skin Conditioning

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Learn more about Adenosine
Antioxidant, Skin Conditioning

Asiaticoside comes from the super popular skin-soothing ingredient, Centella asiatica. It's the reason centella-based products have a strong reputation for repairing and calming skin, along with its sibling compound Madecassoside.

Research from 2016-2025 supports its role in:

You'll usually find this in concentrations between 0.2-5%.

Learn more about Asiaticoside
Skin Conditioning, Stabilising

Asiatic Acid is one of the four main actives found in Centella Asiatica. Its headline job is stimulating collagen.

Lab tests on human skin cells show Asiatic Acid tells your skin to make more collagen, the protein that keeps skin firm and bouncy.

It also calms inflammation and acts as an antioxidant so it can help skin heal faster, rebuild itself, and repair a damaged barrier.

And on naming, even though "acid" is in the name, it's nothing like an AHA or BHA exfoliant. It's a gentle firming and soothing ingredient that supports your skin barrier.

Concentration-wise, Asiatic Acid is potent at very low doses and usually shows up as a small fraction of a broader centella extract.

Analyses of centella material put Asiatic Acid reported in the range of 0.2-3% of the extract.

This ingredient is non-sensitizing and guinea pig sensitization testing also found it to be a weak sensitizer. That means the risk of acquiring contact sensitivty is quite low.

Allergic contact dermatitis does exist but is also very rare; documented cases tend to involve prolonged use on broken skin plus co-sensitization to fragrance ingredients.

Learn more about Asiatic Acid
Masking, Perfuming, Skin Conditioning

This ingredient comes from the bark of the Cedarwood tree.

Though this oil exhibits antibacterial and antioxidant activity, it is also contains skin-irritating fragrances such as limonene.

In 2023, it was listed as an EU known-allergen.

Learn more about Cedrus Atlantica Bark Oil

We don't have a description for Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer yet.

Morus Alba Fruit Extract is an antioxidant.

Citrus Aurantium Dulcis Oil comes from the bitter orange, an orange native to Southeast Asia.

This orange is commonly used in cosmetics and food. It is a common ingredient for marmalade.

Citrus peels are often made up of mainly limonene, a fragrance with a citrus scent. They also contain flavonoids, which have anti-inflammatory properties.

Learn more about Citrus Aurantium Dulcis Oil

We don't have a description for Octanediol yet.

Masking, Perfuming, Skin Conditioning

This ingredient is also known as olive oil. It has been used in skincare for centuries and science largely backs up its reputation as a nourishing emollient.

The main components of olive oil are oleic acid (55-83%), linoleic acid (3.5-20%), and palmitic acid (7-20%). Oleic acid promotes skin regeneration and helps regulate inflammatory responses.

Squalene is also naturally present in olive oil and exhibits moisturizing and antioxidant properties.

The polyphenols in olive oil also show anti-aging promise; one clinical study found a measurable improvement in skin appearance after 30 days of topical serum use.

Just be aware that applying olive oil directly to skin can weaken the barrier and cause redness. One study with volunteers found even people without sensitive skin experienced a significant reduction in stratum corneum integrity and induced mild erythema.

It's best to use this ingredient as part of a carefully crafted formula (instead of putting it on skin directly from the bottle).

Because it has a 2-3 on the comedogenic scale, it is a moderate risk for acne-prone skin. However, the overall formulation of a product matters more than a few ingredients with comedogenic ratings.

This ingredient may not be fungal acne safe because of the oleic and palmitic acid content. These fall within the C11-24 fatty acid range that the Malassezia yeast can metabolize to grow.

Overall, olive oil is a well-studied and nourishing skincare ingredient.

Learn more about Olea Europaea Fruit Oil
Masking, Perfuming, Skin Conditioning

Citrus Grandis Peel Oil is an essential oil that is derived from the peel of a Grapefruit. It is composed largely of limonene, which is a fragrance that can cause irritation for sensitive skin.

Skin Conditioning

Ginkgo Biloba Nut Extract comes from the fruit (nuts) of the Ginkgo Biloba tree. This tree is native to China.

These nuts contain potassium, Vitamin C, calcium, phosphorous, and other minerals.

Emulsion Stabilising, Surfactant

Inulin Lauryl Carbamate is a plant-derived emulsifier and emulsion stabilizer.

It has an interesting party trick: one end of the molecule grabs onto oil while the long (sugar) chains of the molecule wrap around each little oil droplet to hold water against it.

This keeps everything from separating in a formula and also breaks down the oily into tiny droplets so your skin can't feel them (also why these formulas feel light and non-greasy).

Typical usage dose ranges anywhere from 0.2-4.8% depending on how much oil is in the formula, and this ingredient works across a wide pH (4-11) + temperature range.

Safety-wise, it's pretty solid. It is reported as a non-irritant and is even recommended for sensitive-skin and sun care.

Learn more about Inulin Lauryl Carbamate
Emollient, Skin Conditioning

Isocetyl Stearate is an ester of isocetyl alcohol and stearic acid.

Stearate esters are low in viscosity and are oily by nature. Once applied, these stearate esters create a film on your skin. As an emollient, Isocetyl Stearate helps soften and smooth your skin.

One study found Isocetyl Stearate is non-irritating to human skin. However, another study found Isocetyl Stearate to be pore-clogging or comedogenic.

Learn more about Isocetyl Stearate
Masking, Perfuming

This ingredient is also known as Ylang Ylang essential oil.

There are several grades of this oil according to when the flowers are obtained so the exact makeup varies by origin, grade, and extraction.

In cosmetics, its job is mostly sensory: it has a sweet, floral scent often used in perfume.

Chemically, it's complex mix of fragrant molecules: geraniol, limonene, linalool and benzyl benzoate.

Several of these components are on the EU's list of recognized fragrance allergens; this means they have to be labeled when present above 0.001% in leave-on products and 0.01% in rinse-off products.

This ingredient is a known contact sensitizer for a small amount of people so it's definitely worth patch-testing if your skin is reactive.

Lab studies have found the oils does have real antioxidant and antibacterial activity, but keep in mind these are in-vitro findings rather than proven skincare benefits.

Learn more about Cananga Odorata Flower Oil
Humectant, Skin Conditioning

Xylitol is a humectant and prebiotic. It can help with dry skin.

In studies, xylitol has been shown to improve dry skin. It decreased transepidermal water loss, or when water passes through the skin and evaporates. Xylitol also showed to help improve the biomechanical properties of the skin barrier.

The prebiotic property of xylitol may also help reinforce our skin's natural microbiome. Having a healthy microbiome prevents infection by bad bacteria and helps with hydration.

As a humectant, Xylitol helps draw moisture from both the air and from deeper skin layers. This helps keep skin hydrated.

Xylitol is a sugar alcohol and commonly used as a sugar substitute. It is naturally occurring in plants such as strawberries and pumpkin.

Learn more about Xylitol
Humectant, Skin Conditioning

Xylitylglucoside is created from xylitol and glucose, two humectants.

Not surprisingly, this ingredient is also a humectant. It attracts and holds water in your skin, helping to maintain hydration.

This ingredient is most commonly found in a popular trio called Aquaxyl. Aquaxyl is made up of anhydroxylitol(24 - 34%), xylitylglucoside (35 - 50%), and xylitol (5 - 15%).

According to a manufacturer, Aquaxyl is known for a 3-D hydration concept and an anti-dehydration shield to reinforce the outer layer of skin.

Learn more about Xylitylglucoside
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum
Masking

Rose flower oil has citronellol and geraniol. Both of these are known EU allergens and cause contact-allergies.

Masking, Moisturising, Perfuming

Jasminum Officinale Oil is obtained from the jasmine flower. The flower has antioxidant and antimicrobial properties.

The antioxidant properties of Jasmine flower come from flavonoids.

YSK - Jasmine flowers also contain coumarin, a known EU allergen.

Learn more about Jasminum Officinale Oil
Skin Conditioning

Chondrus Crispus Extract comes from a red algae native to the northern Atlantic coasts of Europe and North America. It helps hydrate the skin and is rich in antioxidants.

The antioxidants in chondrus crispus include lutein and zeaxanthin. Lutein has the ability to filter blue light from screens.

Other contents of chondrus crispus include polysaccharides, peptides, and amino acids. These help hydrate the skin.

What's the difference between algae and seaweed?
Algae is a broad term that includes seaweed. Not all algae is seaweed.

Learn more about Chondrus Crispus Extract
Masking, Skin Conditioning

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Learn more about Caprylic/Capric Triglyceride

We don't have a description for Copaifera Officinalis Resin yet.

Buffering, Masking

Tromethamine (aka THAM) is a synthetic amino acid that shows up in skincare as a helper ingredient.

It functions as a pH adjuster to help neutralize acidic ingredients and set a formula's pH to the right spot.

This matters a lot because a lot of actives (like vitamin C) needs a specific pH to work well and feel comfortable on skin.

Concentration use ranges from 0.1-1.0% depending on the formula.

Learn more about Tromethamine
Skin Conditioning

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Learn more about Panthenol
Skin Conditioning

Palmitoyl Tripeptide-5 is a synthetic signal lipopeptide. This just means it is a three amino acid chain bolted onto a palmitic acid tail so it can slip through the skin's lipid barrier.

This peptide has a "build more, lose less" approach.

It's designed to mimic the collagen-stimulating activity in your skin by copying a snippet of one of your skin's own matrix proteins. This nudges fibroblasts into making more collagen while inhibiting the enzyme that breaks down skin protein.

The manufacturer's in vivo study of 45 volunteers found 1% and 2.5% reduced the appearance of wrinkles by 7% and 12% respectively, after using it twice daily for 84 days.

This is in the expected range for peptides; they're slow and cumulative actives and not overnight fixers.

Typical use levels range from 1-3% and this ingredient gets along with pretty much everything.

On the fungal acne front:
Although palmitic acid sits in the chain length that Malassezia can feed on, this ingredient has it locked in an amine bond. This makes it hard for Malassezia to access as a source of food, and therefore fungal acne safe.

Learn more about Palmitoyl Tripeptide-5
Emollient, Emulsifying

Palmitic Acid is a fatty acid naturally found in our skin and in many plant and animal sources.

In cosmetics, it is usually derived from palm oil. It serves many purposes in skincare, acting as a cleanser, emollient, and emulsifier.

Interestingly, topically applied Palmitic Acid can be elongated into longer chain fatty acids and ceramides. A 2019 study found low levels of Palmitic Acid lead to slower development of cells, suggesting it plays a role in keeping your skin's renewal process on track.

The CIR (Cosmetic Ingredient Review) panel determined it safe as used in cosmetics at concentrations up to 13%. It is non-irritating and non-sensitizing in clinical studies.

The culprit behind fungal acne, the Malassezia yeast, feeds on fatty acids with carbon chain lengths between C11-C24. Palmitic Acid, at C16, falls right into that sweet spot.

In vitro studies have shown that Palmitic Acid is one of the fatty acids that induce rapid Malassezia growth in lab settings.

It's worth noting that what feeds yeast in a lab doesn't necessarily feed it on your face since formulation and your skin's chemistry play a bigger role.

Learn more about Palmitic Acid
Preservative

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Learn more about Phenoxyethanol
Skin Conditioning, Solvent

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Learn more about Pentylene Glycol
Skin Conditioning

Polyglyceryl-10 Stearate is a skin conditioner that is basically a fatty acid (stearic acid) hooked up to a chain of glycerin units.

It is a skin conditioning agent that helps skin feel soft, smooth, and hydrated.

Beyond that, it also helps emulsify and cleanse: it helps oil and water phases stay blended in moisturizers, serums, and cleansers.

This ingredient has been found to be safe in cosmetics at present concentrations and practices of use.

Research on Malassezia shows the yeast can metabolize stearic acid as a growth substrate; this ingredient is not fungal acne safe.

Learn more about Polyglyceryl-10 Stearate
Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Emulsion Stabilising

We don't have a description for PEG-14m yet.

Skin Conditioning

Phytosteryl Macadamiate is an ester made by combining phytosterols (the plant version of cholesterol) with fatty acids from macadamia seed oil.

It's a botanical copycat of the cholesteryl esters found in your skin's surface lipids and mimics how your skin's own barrier lipids organize.

Research on phytosterols show they can help with skin barrier recovery and protect skin against UV-induced damage when combined with ceramides.

The fatty acid portion of this ingredient is mainly oleic acid and palmitoleic acid, two potential Malassezia triggers. Be sure to patch test if you're unsure.

Learn more about Phytosteryl Macadamiate
Emulsifying, Skin Conditioning

Hydrogenated Lecithin is a more stable version of lecithin.

It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.

This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.

Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.

A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).

Learn more about Hydrogenated Lecithin
Skin Conditioning

We don't have a description for Hydrolyzed Vegetable Protein yet.

Emollient, Masking, Skin Conditioning

Helianthus Annuus Seed Oil is a plant oil derived from the seeds of a sunflower.

It is rich in fatty acids, primarily linoleic acid and oleic acid. This gives it emollient and skin conditioning properties.

The reason this ingredient is so effective is because it forms a thin film on the skin that reduces transepidermal water loss (TEWL) while supplying linoleic acid to the stratum corneum to improve barrier strength.

The high linoleic acid content is particularly noteworthy for acne-prone skin.

Research suggests that acne-prone skin tends to be deficient in linoleic acid in sebum. Topical application may help replenish this to support a healthier follicular environment and less comedone-promoting sebum.

One randomized study found sunflower seed oil preserved skin barrier integrity in adult volunteers with and without atopic dermatitis (outperforming olive oil).

This ingredient is well-studied, gentle, and an effective emollient suitable for most skin types.

On fungal acne: This ingredient may not be Fungal acne (Malassezia folliculitis) safe. This is because it contains fatty acids with carbon chain lengths in the C11-C24 range.

Learn more about Helianthus Annuus Seed Oil
Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Skin Conditioning, Skin Protecting

Yeast extract is a silky, clear liquid derived from yeast (usually Saccharomyces cerevisiae or Torula yeast).

This ingredient has plenty of skin benefits:

Bioferments of yeast and soy have been found to reduce hyperpigmentation at low levels.

Yeast extract is fungal acne safe because it's made up of amino acids, peptides, B vitamins, and nucleotides (not the C11-C24 fatty acids that Malassezia needs to thrive).

The "yeast" in the name can be misleading, but FA safety is about chemical composition and not ingredient origin.

Learn more about Yeast Extract
Humectant, Skin Conditioning

Hydrolyzed Hyaluronic Acid is hyaluronic acid (HA) that is broken down into lower molecular weight fragments.

It's a humectant that pulls and holds water in the skin to help with hydration, plumpness, and reduce transepidermal water loss.

Because hydrolyzed hyaluronic acid is smaller in size, it can slip past your outermost layer of skin more easily than full-sized HA.

Most formulations will combine all sizes to get the best of both worlds.

Typical usage levels range from 0.01-1%. Any percentage higher than 2% might become goopy and tacky.

Learn more about Hydrolyzed Hyaluronic Acid
Antimicrobial, Perfuming, Tonic

Ferula Galbaniflua Resin Oil is a fragrance and is an oil.

Skin Conditioning

We don't have a description for Limonia Acidissima Extract yet.

We don't have a description for Origanum Vulgare Flower/Leaf/Stem Extract yet.

Skin Conditioning

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Learn more about Ceramide NP

We don't have a description for Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate yet.

Masking, Perfuming, Tonic

Thuja Occidentalis Leaf Oil is a fragrance and is an oil.

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.

As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.

It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.

A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.

Learn more about Acrylates/C10-30 Alkyl Acrylate Crosspolymer

This small molecule peptide has similar benefits to Argireline, the "botox" peptide.

According to the manufacturer, this peptide mimics snake venom to freeze muscles. This prevents muscle movement and contractions to prohibit the formation of fine lines and wrinkles.

While this seems promising, research is lacking in proving this ingredient to be as effective as botox.

Learn more about Dipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning

Madecassic Acid is one of the four star actives in Centella Asiatica. In skincare, it earns its keep as a calming and repairing ingredient.

It works through the same core pathways as the rest of the centella family.

First, it turns down inflammation so it helps with things like redness and general upset skin.

Second, it acts as an antioxidant which means it helps protect skin from daily stress and damage.

And third, it nudges the skin to make more collagen and rebuild its support structure.

That combination is why the whole Centella family is known for calming skin, strengthening the barrier, fading redness, and giving anti-aging benefits.

It's worth being honest about the evidence here; a lot of the strongest data is on the full extract or a Madecassoside/Asiaticoside rather than Madecassic Acid alone. Reviewers also note more long-term clinical trials are needed to confirm the full potential.

Concentration-wise, this ingredient is rarely used pure and usually shows up as part of a standardized centella extract where reported content ranges from 0.02-3.06%.

Finished products typically run somewhere in the 0.1-10% range depending on the format.

In real-world tolerance tests, a repeat-insult patch test on an eye lotion with 0.2% Centella extract showed no irritation or allergic contact dermatitis in 54 subjects. And a mascara with 0.5% Madecassoside caused neither irritation nor sensitization in 109 subjects.

Allergy risk is very low, but not zero. Centella and its constituents are classified as weak contact sensitizers and some rare cases of allergic contact dermatitis exist.

Learn more about Madecassic Acid
Cleansing, Skin Conditioning, Smoothing

Centella Asiatica Extract (Centella) is one of the most researched botanical extracts in skincare with decades of studies backing its effects on inflammation, collagen, and the skin barrier.

That research keeps pointing back to the same four triterpenoid saponins: Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid.

These compounds allow centella to dial back inflammation, encourage the skin to build and hold onto collagen, support the barrier and hydration, and bring solid antioxidant activity to protect against signs of aging.

Centella also carries a nice supporting cast of Vitamin A, vitamin C, several B vitamins, and amino acids. Put it all together and you get an ingredient that soothes, hydrates, and protects, all at once.

Most of centella's magic comes from the four big compounds (Asiaticoside, Madecassoside, Asiatic Acid, and Madecassic Acid). These are the actives doing the heavy lifting in almost every centella study.

Here is the short version of what they do in the skin:

So it is not just soothing for the sake of soothing. Centella calms the skin AND helps it rebuild.

Just FYI, not all centella on an ingredient list is the same. What you are getting actually depends on the extract:

Fun fact on the ratios: the leaves tend to be richest in Madecassoside and Asiaticoside, and lower in the two acids. The exact amounts shift with where the plant is grown and how it is processed. This means purity really does vary brand to brand.

Centella is one of the most easygoing actives out there.

It layers well with basically everything: niacinamide, hyaluronic acid, peptides, and vitamin C, and also pairs nicely with stronger actives like retinoids and exfoliating acids where it can help take the edge off irritation.

On the safety side, centella and its triterpenes are classified as weak sensitizers, meaning allergic reactions are possible but uncommon.

Patch tests at 1% and 5% came back negative in test panels, and creams at typical use levels did not cause allergic reactions across large groups of people.

But as with any new active, a patch test is still a smart move for very reactive skin.

Centella is widely used because it is effective at low percentages. For context, human safety testing found no meaningful irritation from creams containing centella extract at everyday use levels (the tested amounts were well under 1%).

The irritancy threshold in animal testing was also above 30% (so real-world formulas sit far below anything concerning).

In collagen lab studies, higher concentrations drove more collagen synthesis, so serums built around centella tend to feature it more prominently.

Bottom line: you will find centella working nicely anywhere from a fraction of a percent up to hero-ingredient levels depending on whether it is a supporting soother or the main event.

Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Learn more about Centella Asiatica Extract
Emulsifying, Surfactant

Peg-60 Hydrogenated Castor Oil comes from hydrogenated castor oil. It is a solubilizer and emulsifier.

As a solubilizer, it helps dissolve ingredients into a water-based version. It is also an emulsifer. Emulsifier help prevent oils and water from separating. Both these properties help create evenly-spread and uniform products.

Basically, Peg-60 Hydrogenated Castor Oil helps hold ingredients together.

Learn more about PEG-60 Hydrogenated Castor Oil

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Centellian24 is a Korean brand

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· Updated December 10, 2024 Added by imackulate