Versus

MediCube Azelaic Acid Niacinamide Clear Toner Versus MediCube Azelaic Acid 16 BB Calming Serum

Toner
Serum
Korean Brand South Korea
Korean Brand South Korea

Updated on September 18, 2025

Overview

What they are

These products are both cruelty-free and reef safe . They have a total of 18 ingredients in common

Cool Features

They both contain ceramides and niacinamide

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any parabens, silicones or sulfates

What's Inside

They both contain common allergens and fragrances

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside

What's inside

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Azelaic Acid Niacinamide Clear Toner

Water

Skin Conditioning

Propylene Glycol

Humectant
0 / 0 Helps hydrate Dry Skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Azelaic Acid

Buffering
Good for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Sodium Hydroxide

Buffering

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Diethoxyethyl Succinate

Solvent

Trehalose

Humectant
Helps hydrate Dry Skin Icon

C12-14 Alketh-12

Emulsifying

Ethylhexylglycerin

Skin Conditioning

Melia Azadirachta Leaf Extract

Skin Conditioning

Melia Azadirachta Flower Extract

Skin Conditioning

Coccinia Indica Fruit Extract

Skin Conditioning

Solanum Melongena Fruit Extract

Skin Conditioning

Aloe Barbadensis Flower Extract

Emollient

Curcuma Longa Root Extract

Masking
Fragrance Icon

Ocimum Sanctum Leaf Extract

Skin Conditioning
Good for Dark Spots Icon

Coriandrum Sativum Leaf Extract

Antimicrobial

Citrullus Lanatus Fruit Extract

Skin Conditioning
Helps reduce irritation Icon

Cucumis Sativus Fruit Extract

Emollient
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Lavandula Angustifolia Extract

Skin Conditioning
May cause irritation IconEU Allergen Icon

Rosmarinus Officinalis Leaf Extract

Antimicrobial

Chamomilla Recutita Flower Extract

Masking
Helps reduce Skin Redness IconHelps reduce irritation Icon

Chrysanthemum Morifolium Flower Extract

Skin Conditioning

Dipotassium Glycyrrhizate

Humectant
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Glyceryl Caprylate

Emollient

Caprylyl Glycol

Emollient
Fatty Alcohol Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Hydrogenated Lecithin

Emulsifying
Helps hydrate Dry Skin Icon

Glycine

Buffering
Helps hydrate Dry Skin Icon

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Hydrogenated Phosphatidylcholine

Emulsifying

Serine

Masking
Helps hydrate Dry Skin Icon

Glutamic Acid

Humectant
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Centella Asiatica Extract

Cleansing
Helps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Sucrose Stearate

Emollient
0 / 0

Aloe Barbadensis Leaf Extract

Emollient
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Aspartic Acid

Masking
Helps hydrate Dry Skin Icon

Leucine

Skin Conditioning

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Polyglyceryl-10 Stearate

Skin Conditioning
Not safe for Fungal Acne Icon

Alanine

Masking

Lysine

Skin Conditioning

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Arginine

Masking
Good for Scar Healing IconNot safe for Fungal Acne Icon

Tyrosine

Masking

Phenylalanine

Masking
Helps hydrate Dry Skin IconGood for Scar Healing Icon

Valine

Masking

Threonine

Helps hydrate Dry Skin Icon

Proline

Skin Conditioning

Isoleucine

Skin Conditioning

Histidine

Humectant
Helps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Methionine

Skin Conditioning

Pyrus Malus Seed Extract

Skin Conditioning

Ziziphus Jujuba Fruit Extract

Skin Conditioning

Prunus Armeniaca Fruit Extract

Skin Conditioning

Citrus Limon Fruit Extract

Masking
May cause irritation Icon

Hamamelis Virginiana Bark/Leaf Extract

Astringent

Hippophae Rhamnoides Extract

Masking

Ceramide AP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Citrus Aurantium Dulcis Fruit Extract

Masking

Citrus Paradisi Seed Extract

Masking
Fragrance Icon

Madecassoside

Antioxidant
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon

Madecassic Acid

Skin Conditioning
Helps reduce irritation IconHelps with Anti-Aging Icon

Asiaticoside

Antioxidant
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Asiatic Acid

Skin Conditioning
Azelaic Acid 16 BB Calming Serum

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Emollient, Skin Conditioning

Aloe Barbadensis Flower Extract is an extract of the flowers of the aloe, Aloe barbadensis, Liliaceae

Aloe contains the antioxidants Vitamins A, C, and E.

It also contains sugars in the form of monosaccharides and polysaccharides, folic acid, choline, many common minerals such as calcium, 12 anthraquinones, fatty acids, amino acids, and Vitamin B12.

Aloe is known to be anti-inflammatory, moisturizing, antiseptic, healing, and protect against UV rays.

Learn more about Aloe Barbadensis Flower Extract
Buffering, Masking

Azelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin.

What makes azelaic special?

The best thing about azelaic acid is it's gentleness. It's generally well-tolerated and safe to use alongside other actives like niacinamide or salicylic acid.

Unlike AHAs, azelaic acid will not make you photosensitive/sun sensitive.

You can find this ingredient naturally occurring in grains like wheat, rye, and barley. In cosmetics, azelaic acid is typically lab-made, which is more stable and effective.

Learn more about Azelaic Acid
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Cleansing, Skin Conditioning, Smoothing

Centella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.

Centella is rich in antioxidants and amino acids, such as Madecassic Acid and Asiaticoside.

Studies show the compounds in centella help with:

The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.

Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.

Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.

Learn more about Centella Asiatica Extract
Skin Conditioning

Ceramide NP is a type of ceramide.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here:
Ceramide AP
Ceramide EOP

Learn more about Ceramide NP
Skin Conditioning

Coccinia Indica Fruit Extract is also known as Ivy Gourd Fruit Extract. It has skin conditioning properties.

Masking, Perfuming

Curcuma Longa Root Extract is from the spice, turmeric. Besides being a healthy and delicious spice, turmeric also has plenty of skincare benefits. It has anti-inflammatory, antioxidant, and anti-microbial properties.

Turmeric contains curcumin, an antioxidant. Antioxidants help neutralize unstable free-radical molecules. Free-radical molecules may damage your skin's cells and DNA. Curcumin may help with anti-aging.

Curcumin also has anti-inflammatory properties and can help soothe skin and reduce irritation. On top of that, curcumin has been shown to help prevent hyperpigmentation from sun damage.

The anti-microbial property of turmeric can make it effective in treating acne. This property has also been shown to help regulate the production of sebum.

Learn more about Curcuma Longa Root Extract
Emollient, Emulsifying

Glyceryl Caprylate comes from glycerin and caprylic acid, a fatty acid from coconut. It has emollient and emulsifier properties.

As an emollient, it helps hydrate your skin. Emollients work by creating a barrier on your skin to trap moisture in, helping to keep your skin soft and smooth.

On the other hand, emulsifiers prevent ingredients (such as oil and water) from separating.

Learn more about Glyceryl Caprylate

Melia Azadirachta Flower Extract is from the Neem tree. Neem trees originate from India.

Melia Azadirachta Flower Extract contains antioxidants. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

The flowers of this tree are lilac colored.

Learn more about Melia Azadirachta Flower Extract
Skin Conditioning

Melia Azadirachta Leaf Extract is extract from the neem plant.

The leaves of this tree contain flavonoids and polyphenols. These two compounds are antioxidants, anti-inflammatory, and antibacterial. Further research is needed as to their effects when applied on skin.

Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide
Skin Conditioning

Ocimum Sanctum Leaf Extract comes from the Holy Basil plant. Holy Basil is native to India.

Holy Basil is rich in antioxidants due to its high romarinic acid, ferulic acid, and rutin content. This gives it skin brightening and soothing properties.

While Holy Basil has many claims to help fight acne, more research is needed.

One thing to note is the presence of tannins; tannins are naturally found in nature. However, this compound may be skin-sensitizing.

Learn more about Ocimum Sanctum Leaf Extract
Skin Conditioning

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Learn more about Panthenol
Humectant, Skin Conditioning, Solvent

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.

This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.

Those with sensitive skin or conditions may develop a rash when using this ingredient.

Learn more about Propylene Glycol
Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Learn more about Sodium Hydroxide

We don't have a description for Solanum Melongena Fruit Extract yet.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

6 Routines
33% use in am
50% use in pm
67% use every day
34 Routines
56% use in am
44% use in pm
88% use every day
When to use See routines that use it ->