Anua Azelaic Acid 15+ Intense Calming Serum Versus MediCube Azelaic Acid 16 BB Calming Serum
Updated on March 29, 2025
Overview
What they are
These products are both cruelty-free and reef safe serums. They have a total of 13 ingredients in common
Cool Features
They both contain ceramides
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any common allergens, parabens, silicones or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Anua Azelaic Acid 15+ Intense Calming Serum 44 ingredients
MediCube Azelaic Acid 16 BB Calming Serum 31 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
Anua Azelaic Acid 15+ Intense Calming Serum 44 ingredients
MediCube Azelaic Acid 16 BB Calming Serum 31 ingredients
Key Ingredients
Benefits
Ingredients Side-by-side
Water
Skin ConditioningPropylene Glycol
Humectant
Azelaic Acid
Buffering
Sodium Hydroxide
Buffering1,2-Hexanediol
Skin ConditioningCentella Asiatica Extract
Cleansing
Dipropylene Glycol
MaskingButylene Glycol
Humectant
Panthenol
Skin Conditioning
Hydroxyethylcellulose
Emulsion StabilisingGlycerin
Humectant
Ethylhexylglycerin
Skin ConditioningMelia Azadirachta Leaf Extract
Skin ConditioningSalicylic Acid
Masking
Biosaccharide Gum-1
Skin ConditioningAllantoin
Skin Conditioning
Dipotassium Glycyrrhizate
Humectant
Melia Azadirachta Flower Extract
Skin ConditioningSodium Hyaluronate
Humectant
Phormium Tenax Leaf Water
Antioxidant
Succinic Acid
BufferingTotarol
Antioxidant
Beta-Glucan
Skin Conditioning
Dextrin
AbsorbentTheobroma Cacao Extract
Skin ConditioningCentella Asiatica Leaf Extract
Skin Conditioning
Centella Asiatica Root Extract
Skin Conditioning
Madecassoside
Antioxidant
Asiaticoside
Antioxidant
Asiatic Acid
Skin ConditioningMadecassic Acid
Skin Conditioning
Tocopherol
Antioxidant
Squalane
Emollient
Zinc PCA
Humectant
Chlorella Sp. Hs2 Extract
Skin ConditioningCeramide NP
Skin Conditioning
Sodium Hyaluronate Dimethylsilanol
HumectantHydrolyzed Hyaluronic Acid
Humectant
Hydrolyzed Sodium Hyaluronate
Skin ConditioningHyaluronic Acid
Humectant
Potassium Hyaluronate
Skin ConditioningHydroxypropyltrimonium Hyaluronate
Sodium Hyaluronate Crosspolymer
Humectant
Sodium Acetylated Hyaluronate
Humectant
Water, Propylene Glycol, Azelaic Acid, Sodium Hydroxide, 1,2-Hexanediol, Centella Asiatica Extract, Dipropylene Glycol, Butylene Glycol, Panthenol, Hydroxyethylcellulose, Glycerin, Ethylhexylglycerin, Melia Azadirachta Leaf Extract, Salicylic Acid, Biosaccharide Gum-1, Allantoin, Dipotassium Glycyrrhizate, Melia Azadirachta Flower Extract, Sodium Hyaluronate, Phormium Tenax Leaf Water, Succinic Acid, Totarol, Beta-Glucan, Dextrin, Theobroma Cacao Extract, Centella Asiatica Leaf Extract, Centella Asiatica Root Extract, Madecassoside, Asiaticoside, Asiatic Acid, Madecassic Acid, Tocopherol, Squalane, Zinc PCA, Chlorella Sp. Hs2 Extract, Ceramide NP, Sodium Hyaluronate Dimethylsilanol, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hyaluronic Acid, Potassium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Acetylated Hyaluronate
Water
Skin ConditioningAzelaic Acid
Buffering
Butylene Glycol
Humectant
Propanediol
SolventSodium Hydroxide
BufferingPropylene Glycol
Humectant
Alcohol Denat.
Antimicrobial
1,2-Hexanediol
Skin ConditioningNiacinamide
Smoothing
Citric Acid
Buffering
Glyceryl Caprylate
EmollientMelia Azadirachta Leaf Extract
Skin ConditioningMelia Azadirachta Flower Extract
Skin ConditioningCoccinia Indica Fruit Extract
Skin ConditioningAloe Barbadensis Flower Extract
EmollientSolanum Melongena Fruit Extract
Skin ConditioningOcimum Sanctum Leaf Extract
Skin ConditioningAllantoin
Skin Conditioning
Centella Asiatica Extract
Cleansing
Panthenol
Skin Conditioning
Curcuma Longa Root Extract
Masking
Corallina Officinalis Extract
Skin ConditioningPantothenic Acid
Skin ConditioningNicotinamide Mononucleotide
Antioxidant
Hydrolyzed Pea Protein
EmollientPhytosterols
Skin ConditioningLecithin
EmollientOlea Europaea Fruit Oil
Masking
Squalane
Emollient
Butyrospermum Parkii Butter
Skin Conditioning
Ceramide NP
Skin Conditioning
Water, Azelaic Acid, Butylene Glycol, Propanediol, Sodium Hydroxide, Propylene Glycol, Alcohol Denat., 1,2-Hexanediol, Niacinamide, Citric Acid, Glyceryl Caprylate, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Aloe Barbadensis Flower Extract, Solanum Melongena Fruit Extract, Ocimum Sanctum Leaf Extract, Allantoin, Centella Asiatica Extract, Panthenol, Curcuma Longa Root Extract, Corallina Officinalis Extract, Pantothenic Acid, Nicotinamide Mononucleotide, Hydrolyzed Pea Protein, Phytosterols, Lecithin, Olea Europaea Fruit Oil, Squalane, Butyrospermum Parkii Butter, Ceramide NP
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterPropylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.
Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.
This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.
Those with sensitive skin or conditions may develop a rash when using this ingredient.
Learn more about Propylene GlycolAzelaic acid is a naturally occurring acid derived from grains. This ingredient is effective in treating acne, rosacea, and other skin conditions.
It has been shown to reduce the growth of acne-causing bacteria and helps reduce inflammation. On top of that, it helps reduce the production of sebum and unclog pores.
Azelaic Acid also has antioxidant properties. Antioxidants protect our skin cells from free-radical damage.
One of the main benefits of azelaic acid is that it is gentle and well-tolerated by most people.
Fun fact: The lab-created form of azelaic acid is typically used within cosmetic products for its shelf-stability.
Learn more about Azelaic AcidSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium Hydroxide1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Centella Asiatica Extract (Centella) is derived from an herb native to Southeast Asia. It is famous for its anti-inflammatory and soothing properties.
Centella is rich in antioxidants and amino acids, such as Madecassic Acid and Asiaticoside.
Studies show the compounds in centella help with:
The combination of all these properties makes centella effective at soothing, hydrating, and protecting the skin.
Other great components of centella include Vitamin A, vitamin C, several B vitamins, and Asiatic Acid.
Fun fact: Centella has been used as a medicine and in food for many centuries. As a medicine, it is used to treat burns, scratches, and wounds.
Learn more about Centella Asiatica ExtractButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
- It is a solvent, meaning that it helps to dissolve other ingredients. This also enhances the absorption of the product into one's skin.
- It is a humectant, which means that it helps attract moisture into the skin.
- It helps improve product application.
- It has mild preservative properties.
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolMelia Azadirachta Leaf Extract is extract from the neem plant.
The leaves of this tree contain flavonoids and polyphenols. These two compounds are antioxidants, anti-inflammatory, and antibacterial. Further research is needed as to their effects when applied on skin.
Allantoin plays a role in soothing and moisturizing the skin. Because of this, it is often added to products with strong active ingredients.
Some studies have shown this ingredient can promote wound healing with higher concentrations.
Allantoin is derived from the comfrey plant but produced synthetically for cosmetic products to ensure purity.
Learn more about AllantoinMelia Azadirachta Flower Extract is from the Neem tree. Neem trees originate from India.
Melia Azadirachta Flower Extract contains antioxidants. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
The flowers of this tree are lilac colored.
Learn more about Melia Azadirachta Flower ExtractSqualane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.
Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.
Research shows that squalane is non-irritating (even at 100% concentration).
In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.
The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.
Is squalane vegan?
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Learn more about SqualaneCeramide NP is a type of ceramide.
Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.
Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.
If you would like to eat ceramides, sweet potatoes contain a small amount.
Read more about other common types of ceramides here: Ceramide AP Ceramide EOP
Learn more about Ceramide NPIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Anua Azelaic Acid 15+ Intense Calming Serum 44 ingredients
MediCube Azelaic Acid 16 BB Calming Serum 31 ingredients
Reviews
Here's what our community thinks
Anua Azelaic Acid 15+ Intense Calming Serum 44 ingredients
For the short time that I've used this serum Ive grown to love it. A great serum for acne prone/irritated skin. This serum has helped the redness in my face as well as my post acne marks almost clear completely. Highly recommended.
This serum is VERY VERY POTENT the 5% difference from the AZ 10 is a real difference, I use it as a spot treatment for now, it literally kills any inflamed acne overnight and makes it go away in 3 days, worked for whiteheads, pimples and even under the skin bumps and cysts that I felt coming to a head went back down after applying for 3-6 days. I don't know I will try and see if I can work up to Show more
