Versus

MEDI-PEEL Melanon X Ampoule Versus Nature Republic Vitapair C Pure Vitamin C 20 Whitening Ampoule

Ampoule
Ampoule
Korean Brand
Korean Brand

Updated on October 31, 2024

Overview

What they are

These products are both reef safe ampoules. They have a total of 15 ingredients in common

Cool Features

They both contain niacinamide, retinoid, Vitamin C and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, parabens, silicones or sulfates

What's Inside

They both contain oils

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Melanon X Ampoule

Water

Skin Conditioning

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Butyrospermum Parkii Butter

Skin Conditioning
Helps hydrate Dry Skin IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

PPG-20 Methyl Glucose Ether

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Terminalia Ferdinandiana Fruit Extract

Antioxidant
Antioxidant Icon

Methyl Glucose Sesquistearate

Emollient
Not safe for Fungal Acne Icon

Pyrus Malus Fruit Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Carica Papaya Fruit Extract

Skin Conditioning

Eel Extract

Humectant

Propanediol

Solvent
Helps hydrate Dry Skin Icon

Cetearyl Olivate

Not safe for Fungal Acne Icon

Sorbitan Olivate

Emulsifying
Not safe for Fungal Acne Icon

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Carbomer

Emulsion Stabilising
1 / 0

Caprylyl Glycol

Emollient

Inulin Lauryl Carbamate

Emulsion Stabilising

Tromethamine

Buffering

Lavandula Angustifolia Flower Extract

Cleansing
May cause irritation IconEU Allergen Icon

Michelia Alba Flower Extract

Skin Conditioning

Salvia Officinalis Extract

Antimicrobial
Antioxidant Icon

Centaurea Cyanus Flower Extract

Astringent

Alpha-Arbutin

Antioxidant
Antioxidant IconGood for Dark Spots IconGood for Scar Healing Icon

Clay Extract

Skin Conditioning

Boletus Edulis Whole Plant Extract

Perfuming
Fragrance Icon

Vitex Trifolia Fruit Extract

Skin Conditioning

Adenosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing Icon

Lactobacillus Ferment

Skin Conditioning

Xanthan Gum

Emulsifying

Disodium EDTA

Elaeis Guineensis Kernel Oil

Emollient
Oil IconNot safe for Fungal Acne Icon

Hydrogenated Lecithin

Emulsifying
Helps hydrate Dry Skin Icon

Calcium Pantothenate

Maltodextrin

Absorbent
Helps hydrate Dry Skin Icon

Sodium Starch Octenylsuccinate

Absorbent

Garcinia Indica Fruit Extract

Humectant

Glutathione

Good for Dark Spots Icon

Camellia Sinensis Flower Extract

Perfuming
Fragrance Icon

Alteromonas Ferment Extract

Skin Conditioning
Helps reduce irritation Icon

Phenethyl Alcohol

Masking

Hydrolyzed Sponge

Skin Conditioning

Artemisia Annua Extract

Masking

Pentylene Glycol

Skin Conditioning

Citrus Tangerina Peel Extract

Astringent

Sodium Ascorbyl Phosphate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Hydrolyzed Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Hyaluronic Acid

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Pyridoxine Hcl

Skin Conditioning

Ethylhexylglycerin

Skin Conditioning

Sucrose Palmitate

Emollient

Ascorbic Acid

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Menadione

Masking

Polyglyceryl-4 Oleate

Emulsifying
Not safe for Fungal Acne Icon

Linoleic Acid

Cleansing
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Retinyl Palmitate

Skin Conditioning
1-3 / 1-3 Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconNot safe for Fungal Acne IconMay worsen Rosacea Icon

Arachis Hypogaea Oil

Skin Conditioning
2 / 0 Oil IconNot safe for Fungal Acne Icon

Sodium Phosphate

Buffering

Linolenic Acid

Cleansing
Fragrance IconHelps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconNot safe for Fungal Acne Icon

Lecithin

Emollient
Helps hydrate Dry Skin Icon

Retinol

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Silica

Abrasive
Exfoliant IconMay worsen Eczema IconMay worsen Rosacea Icon

Tranexamic Acid

Astringent
Helps reduce irritation IconGood for Dark Spots IconGood for Scar Healing Icon

Rosmarinus Officinalis Leaf Extract

Antimicrobial

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging Icon

Helianthus Annuus Seed Oil

Emollient
0 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Sh-Oligopeptide-1

Skin Conditioning
Peptide IconHelps with Anti-Aging IconGood for Scar Healing Icon

Sh-Oligopeptide-2

Skin Conditioning
Peptide Icon

Sh-Polypeptide-1

Skin Conditioning
Peptide Icon

Sh-Polypeptide-10

Skin Conditioning
Peptide Icon

Sh-Polypeptide-60

Skin Conditioning
Peptide Icon

Citrus Limon Peel Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen Icon

Limonene

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Citral

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Rosacea Icon

Hexyl Cinnamal

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Linalool

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Benzyl Salicylate

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Water, Panthenol, Butylene Glycol, Butyrospermum Parkii Butter, Niacinamide, 1,2-Hexanediol, PPG-20 Methyl Glucose Ether, Glycerin, Terminalia Ferdinandiana Fruit Extract, Methyl Glucose Sesquistearate, Pyrus Malus Fruit Extract, Carica Papaya Fruit Extract, Eel Extract, Propanediol, Cetearyl Olivate, Sorbitan Olivate, Caprylic/Capric Triglyceride, Carbomer, Caprylyl Glycol, Inulin Lauryl Carbamate, Tromethamine, Lavandula Angustifolia Flower Extract, Michelia Alba Flower Extract, Salvia Officinalis Extract, Centaurea Cyanus Flower Extract, Alpha-Arbutin, Clay Extract, Boletus Edulis Whole Plant Extract, Vitex Trifolia Fruit Extract, Adenosine, Lactobacillus Ferment, Xanthan Gum, Disodium EDTA, Elaeis Guineensis Kernel Oil, Hydrogenated Lecithin, Calcium Pantothenate, Maltodextrin, Sodium Starch Octenylsuccinate, Garcinia Indica Fruit Extract, Glutathione, Camellia Sinensis Flower Extract, Alteromonas Ferment Extract, Phenethyl Alcohol, Hydrolyzed Sponge, Artemisia Annua Extract, Pentylene Glycol, Citrus Tangerina Peel Extract, Sodium Ascorbyl Phosphate, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Tocopheryl Acetate, Pyridoxine Hcl, Ethylhexylglycerin, Sucrose Palmitate, Ascorbic Acid, Tocopherol, Menadione, Polyglyceryl-4 Oleate, Linoleic Acid, Retinyl Palmitate, Arachis Hypogaea Oil, Sodium Phosphate, Linolenic Acid, Lecithin, Retinol, Silica, Tranexamic Acid, Rosmarinus Officinalis Leaf Extract, Acetyl Hexapeptide-8, Helianthus Annuus Seed Oil, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-10, Sh-Polypeptide-60, Citrus Limon Peel Oil, Limonene, Citral, Hexyl Cinnamal, Linalool, Benzyl Salicylate

Vitapair C Pure Vitamin C 20 Whitening Ampoule

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. 

It is a:

  • Humectant, drawing moisture into the skin
  • Emollient, helping to soften skin
  • Solvent, dispersing and stabilizing formulas
  • Preservative booster, enhancing the antimicrobial activity of other preservatives 
Skin Conditioning

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.

Studies have found adenosine may also help with wound healing.

In skincare products, Adenosine is usually derived from yeast.

Learn more about Adenosine
Antioxidant, Buffering, Masking

Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.

Not only is vitamin C great for your overall health and immune system, it also has plenty of benefits on your skin.

Vitamin C is best used for brightening skin. It improves dark spots, acne scars, and hyperpigmentation. This is because it blocks the process of skin darkening when exposed to UV.

Remember: Vitamin C should not replace sunscreen!

Your skin uses vitamin C to build collagen. Collagen is one key component in having a strong skin barrier and plump skin. Vitamin C also plays a role in regulating collagen, thus making it effective in improving wrinkles and fine lines.

Ascorbic acid shows potent antioxidant activity. As an antioxidant, it helps fight free-radicals. Free-radicals are molecules that may damage your skin cells. These antioxidants also protect skin against UV damage.

The best formulations include Vitamin E and/or ferulic acid. These two ingredients help stabilize and provide a boost in the benefits of ascorbic acid. This is because ascorbic acid becomes unstable when exposed to UV and air. In fact, you can tell your ascorbic acid has oxidized when it turns an orange-yellow color.

Ascorbic acid is generally compatible with other ingredients. However, using ascorbic acid with other active ingredients might cause irritation. Two ingredients: copper ions and benzoyl peroxide, will inactivate ascorbic acid completely.

Read more about other types of Vitamin C:

Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.

Learn more about Ascorbic Acid
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol

Glutathione is an antioxidant naturally found in our bodies. It is made up of three amino acids: glycine, cysteine, and glutamic acid.

As an antioxidant, it prevents oxidative damage to parts of our cell.

While glutathione is said to help with fading dark spots, the results from research are inconclusive. Further studies are needed. With that said, gluthatione has been shown to protect our skin from UV-B induced damage.

This ingredient is naturally occurring in plants, animals, fungi, and some bacteria.

Learn more about Glutathione
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Masking

We don't have a description for Menadione yet.

Smoothing

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Learn more about Niacinamide
Skin Conditioning

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Learn more about Panthenol
Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.

This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.

Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.

Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.

Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.

Learn more about Pentylene Glycol
Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Skin Conditioning

Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.

Why is retinol famous?

It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.

Retinol is proven to:

This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.

Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).

Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

We recommend speaking with a medical professional about using this ingredient during pregnancy.

Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.

Read about Tretinoin

Learn more about Retinol

Sodium Ascorbyl Phosphate is a form of Vitamin C. It is the salt of ascorbic acid.

This ingredient is more gentle than ascorbic acid. It is also more stable when exposed to light and oxygen.

Vitamin C helps reduce redness, improve skin texture, reduce the effects of aging, reduce the visibility of dark spots, and brighten skin.

Your skin uses Vitamin C to produce collagen and collagen production plays a role in having a strong skin barrier and plump skin. As an antioxidant, this ingredient also helps reduce the signs of aging such as fine-lines and wrinkles.

VItamin C helps brighten skin by blocking the process of skin darkening.

In a 2011 study, Sodium Ascorbyl Phosphate was found to have antibacterial properties. This may help treat acne.

Read more about other types of Vitamin C:

Learn more about Sodium Ascorbyl Phosphate
Antioxidant, Masking, Skin Conditioning

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

4 Routines
50% use in am
50% use in pm
50% use every on_specific_days
4 Routines
100% use in am
0% use in pm
75% use every day