Versus

ISDIN Isdinceutics Retinal Intense Serum Versus Is Clinical Retinol+ Emulsion 0.3

Serum
Emulsion
Spanish Brand
American Brand

Updated on May 26, 2025

Overview

What they are

These products are both reef safe . They have a total of 12 ingredients in common

Cool Features

They both contain peptides, retinoid, Vitamin C and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any common allergens, parabens or sulfates

What's Inside

They both contain fragrances

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Isdinceutics Retinal Intense Serum
Retinol+ Emulsion 0.3

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Pentylene Glycol

Skin Conditioning

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Ectoin

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Glyceryl Citrate/Lactate/Linoleate/Oleate

Emulsifying
Not safe for Fungal Acne Icon

Polyglyceryl-4 Cocoate

Emollient
Can worsen Dry Skin IconNot safe for Fungal Acne Icon

Polyglyceryl-3 Cocoate

Emulsifying
Can worsen Dry Skin IconNot safe for Fungal Acne Icon

Glyceryl Caprylate

Emollient

Chlorella Vulgaris Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Bakuchiol

Antimicrobial
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging IconGood for Dark Spots IconHelps brighten skin Icon

Triethanolamine

Buffering
2 / 0

Carbomer

Emulsion Stabilising
1 / 0

Retinol

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Phragmites Communis Extract

Skin Conditioning

Poria Cocos Extract

Skin Conditioning

Oryza Sativa Bran Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Rosmarinus Officinalis Leaf Extract

Antimicrobial

Phosphatidylcholine

Emulsifying

Propanediol

Solvent
Helps hydrate Dry Skin Icon

Butyrospermum Parkii Butter

Skin Conditioning
Helps hydrate Dry Skin IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Lecithin

Emollient
Helps hydrate Dry Skin Icon

Lactic Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Polysorbate 40

Emulsifying
Not safe for Fungal Acne Icon

Helianthus Annuus Extract

Emollient
Helps hydrate Dry Skin Icon

Phenoxyethanol

Preservative
Preservative Icon

Polyacrylamide

C13-16 Isoparaffin

Solvent
May worsen Oily Skin IconNot safe for Fungal Acne Icon

Laureth-7

Emulsifying

Tripeptide-1

Skin Conditioning
Peptide IconHelps with Anti-Aging Icon

Dextran

Helps hydrate Dry Skin Icon

Ascorbic Acid

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon

Colloidal Gold

Antimicrobial

Glutathione

Good for Dark Spots Icon

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Heptyl Undecylenate

Emollient
Not safe for Fungal Acne Icon

C13-16 Isoalkane

Solvent

Dipotassium Glycyrrhizate

Humectant
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Bidens Pilosa Extract

Humectant

Elaeis Guineensis Oil

Emollient
Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Gossypium Herbaceum Seed Oil

Skin Conditioning
3 / 2 Oil IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Linum Usitatissimum Seed Oil

Perfuming
Fragrance IconOil IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon

Glycine Soja Extract

Skin Conditioning

Sodium Hydroxide

Buffering

Disodium EDTA

Phenylpropanol

Masking
Fragrance Icon

Ethylhexylglycerin

Skin Conditioning

Caprylyl/Capryl Glucoside

Cleansing

Diisopropyl Adipate

Emollient
0 / 0

Triethyl Citrate

Masking
Fragrance Icon

Xanthan Gum

Emulsifying

Sorbitol

Humectant
0 / 0 Helps hydrate Dry Skin Icon

Parfum

Masking
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Antioxidant, Buffering, Masking

Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.

Not only is vitamin C great for your overall health and immune system, it also has plenty of benefits on your skin.

Vitamin C is best used for brightening skin. It improves dark spots, acne scars, and hyperpigmentation. This is because it blocks the process of skin darkening when exposed to UV.

Remember: Vitamin C should not replace sunscreen!

Your skin uses vitamin C to build collagen. Collagen is one key component in having a strong skin barrier and plump skin. Vitamin C also plays a role in regulating collagen, thus making it effective in improving wrinkles and fine lines.

Ascorbic acid shows potent antioxidant activity. As an antioxidant, it helps fight free-radicals. Free-radicals are molecules that may damage your skin cells. These antioxidants also protect skin against UV damage.

The best formulations include Vitamin E and/or ferulic acid. These two ingredients help stabilize and provide a boost in the benefits of ascorbic acid. This is because ascorbic acid becomes unstable when exposed to UV and air. In fact, you can tell your ascorbic acid has oxidized when it turns an orange-yellow color.

Ascorbic acid is generally compatible with other ingredients. However, using ascorbic acid with other active ingredients might cause irritation. Two ingredients: copper ions and benzoyl peroxide, will inactivate ascorbic acid completely.

Read more about other types of Vitamin C:

Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.

Learn more about Ascorbic Acid
Antimicrobial, Antioxidant, Emollient

Bakuchiol is a plant-derived antioxidant (it's vegan!). It is often called the replacement for retinol although it is not part of the same family.

It has similar effects as retinol: skin smoothing, reducing discoloration, and preventing wrinkles. It does not cause as much irritation as traditional retinoids.

Bakuchiol works by breaking down free radicals and stimulating collagen production in skin.

Combining bakuchiol with retinol will not have adverse side effects. Studies show using them will just boost the benefits. Bakuchiol is also found to help stabilize retinol.

While bakuchiol does not make the skin more sun sensitive, we recommend wearing SPF on a daily basis.

Read more about traditional retinol

Learn more about Bakuchiol
Masking, Skin Conditioning

This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Masking, Perfuming

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Learn more about Parfum
Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.

This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.

Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.

Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.

Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.

Learn more about Pentylene Glycol
Solvent

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. 

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Learn more about Propanediol
Antimicrobial, Masking, Skin Conditioning

Rosmarinus Officinalis Leaf Extract comes from rosemary. Rosemary is native to the Mediterranean.

While Rosmarinus Officinalis Leaf Oil can be volatile due to its fragrant properties, the fragrance components are usually removed in the leaf extract.

Rosemary Leaf Extract contains many antioxidants such as rosmarinic acid and caffeic acid. Rosemarinic acid, a compound found in rosemary leaf, has been found to help soothe skin conditions such as eczema and acne.

Learn more about Rosmarinus Officinalis Leaf Extract
Antioxidant, Masking, Skin Conditioning

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum

When to use

20 Routines
0% use in am
100% use in pm
70% use every day
5 Routines
0% use in am
100% use in pm
60% use every day