Versus

Clinique Smart Clinical Repair Wrinkle Correcting Serum Versus Origins Plantscription Multi-Powered Youth Serum

Serum
Serum
American Brand United States
American Brand United States

Updated on March 06, 2025

Overview

What they are

These products are both reef safe serums. They have a total of 21 ingredients in common

Cool Features

They both contain hyaluronic acid, peptides and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, parabens or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside

What's inside

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Smart Clinical Repair Wrinkle Correcting Serum

Water

Skin Conditioning

Dimethicone

Emollient
1 / 0 Silicon Icon

Isododecane

Emollient

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Polysilicone-11

Ascorbyl Glucoside

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Hypnea Musciformis Extract

Skin Protecting

Gelidiella Acerosa Extract

Skin Protecting

Sigesbeckia Orientalis Extract

Skin Conditioning

Helianthus Annuus Seed Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Hordeum Vulgare Extract

Emollient

Triticum Vulgare Germ Extract

Skin Conditioning

Cucumis Sativus Fruit Extract

Emollient
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Caffeine

Skin Conditioning
Helps reduce irritation IconHelps with Anti-Aging Icon

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging Icon

Palmitoyl Tripeptide-1

Skin Conditioning
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Palmitoyl Tetrapeptide-7

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Palmitoyl Hexapeptide-12

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

PEG-10 Dimethicone

Skin Conditioning
Silicon Icon

Glycyrrhetinic Acid

Skin Conditioning

Lactis Proteinum

Skin Conditioning

Isohexadecane

Emollient

Propylene Glycol Dicaprate

Emollient

Caprylyl Glycol

Emollient

Hydroxypinacolone Retinoate

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Acetyl Glucosamine

Skin Conditioning

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

PEG-8

Humectant

Yeast Extract

Skin Conditioning
Not safe for Fungal Acne Icon

PEG-6

Humectant

Dimethyl Isosorbide

Solvent

Glyceryl Polymethacrylate

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Sodium Phosphate

Buffering

Synthetic Fluorphlogopite

Polysorbate 80

Emulsifying
0 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Carbomer

Emulsion Stabilising
1 / 0

Hexylene Glycol

Emulsifying
0-2 / 0-1

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer

Emulsion Stabilising

Potassium Hydroxide

Buffering

Tin Oxide

Abrasive
Exfoliant Icon

Disodium Phosphate

Buffering

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Disodium EDTA

Sodium Citrate

Buffering

Phenoxyethanol

Preservative
Preservative Icon

Potassium Sorbate

Preservative
Preservative Icon

CI 77891

Cosmetic Colorant
Plantscription Multi-Powered Youth Serum

Water

Skin Conditioning

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Heptyl Undecylenate

Emollient
Not safe for Fungal Acne Icon

Octyldodecanol

Emollient

Glycereth-26

Humectant
0 / 0 Helps hydrate Dry Skin Icon

Sodium Acrylates Copolymer

Algae Extract

Emollient
May worsen Oily Skin Icon

Illicium Verum Fruit/Seed Oil

Masking
Oil Icon

Citrus Aurantium Bergamia Fruit Oil

Masking
Fragrance IconOil Icon

Pelargonium Graveolens Flower Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen Icon

Lavandula Angustifolia Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen Icon

Citrus Limon Peel Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen Icon

Litsea Cubeba Fruit Oil

Masking
Fragrance IconOil Icon

Citrus Nobilis Peel Oil

Masking
Oil Icon

Myristica Fragrans Kernel Oil

Masking
Oil IconNot safe for Fungal Acne Icon

Citrus Aurantium Dulcis Oil

Masking
Oil Icon

Rosa Damascena Flower Oil

Masking
Oil Icon

Hibiscus Abelmoschus Extract

Masking

Carthamus Tinctorius Seed Oil

Masking
0-2 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Linalool

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Geraniol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Citronellol

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Limonene

Perfuming
Fragrance IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon

Anogeissus Leiocarpus Bark Extract

Skin Protecting

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging Icon

Palmitoyl Tripeptide-1

Skin Conditioning
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Acetyl Octapeptide-3

Humectant
Peptide IconHelps with Anti-Aging Icon

Palmitoyl Tetrapeptide-7

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Palmitoyl Hexapeptide-12

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Skin Conditioning
Peptide IconHelps with Anti-Aging Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Sigesbeckia Orientalis Extract

Skin Conditioning

Commiphora Mukul Resin Extract

Skin Conditioning

Laminaria Saccharina Extract

Skin Protecting

Glucosamine Hcl

Bambusa Vulgaris Extract

Skin Conditioning
Helps reduce irritation Icon

Caffeine

Skin Conditioning
Helps reduce irritation IconHelps with Anti-Aging Icon

Rosmarinus Officinalis Leaf Extract

Antimicrobial

Saccharum Officinarum Extract

Moisturising

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Scutellaria Baicalensis Root Extract

Astringent

Pyrus Malus Fruit Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Cucumis Sativus Fruit Extract

Emollient
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Pisum Sativum Extract

Skin Conditioning

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Lecithin

Emollient
Helps hydrate Dry Skin Icon

Xanthan Gum

Emulsifying

Caprylyl Glycol

Emollient

Hexylene Glycol

Emulsifying
0-2 / 0-1

PEG-8

Humectant

Glyceryl Polymethacrylate

Carbomer

Emulsion Stabilising
1 / 0

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Sodium Metabisulfite

Antioxidant
Antioxidant IconPreservative Icon

Sodium Sulfite

Preservative
Preservative Icon

Disodium EDTA

Sodium Phytate

BHT

Antioxidant
Antioxidant Icon

Potassium Sorbate

Preservative
Preservative Icon

Phenoxyethanol

Preservative
Preservative Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Humectant, Skin Conditioning

Acetyl Hexapeptide-8, commonly known as Argireline, is a popular peptide in skincare. It’s often referred to as a “Botox-like” ingredient because it helps reduce muscle movement.

By relaxing these micro-movements, Argireline may help minimize the appearance of fine lines and wrinkles. That said, it’s not as powerful as Botox, and research on its long-term effectiveness is still limited.

Beyond smoothing, Argireline may also support collagen production. Collagen is the protein that helps keep your skin firm, bouncy, and well-hydrated by strengthening the skin barrier.

So while Argireline isn’t a miracle fix, it can be a helpful addition to a routine focused on both prevention and skin health.

Read more about other common types of peptides here:

Learn more about Acetyl Hexapeptide-8
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Skin Conditioning

Caffeine is most associated with coffee, tea, and cacao. In skincare, it helps with calming inflammation and is rich in antioxidants.

While caffeine is used to treat cellulite and and dark circles, further studies are needed to prove this. It has been believed to help with these skin conditions due to its ability to dilate blood vessels and increase blood flow.

Some studies are looking into caffeine's ability to protect against UV rays.

Learn more about Caffeine
Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Emollient, Skin Conditioning

This extract comes from cucumber. Cucumbers are mostly made up of water (95%), and the other 5% is composed of: vitamin C, caffeic acid, fatty acids, amino acids, and other minerals.

Cucumbers have anti-inflammatory, barrier repair, and hydrating properties.

They contain shikimate dehydrigenase, an enzyme shown to help reduce inflammation and soothe the skin.

The amino acids found in cucumbers help nourish our skin's natural acid mantle (it's an important part of our skin barrier). This slightly acidic film acts as a barrier to protect us from bacteria, viruses, and other contaminants.

Unless you have an allergy to cucumbers, this is generally a non-irritating ingredient.

Fun fact: Cucumis Sativus is native to South Asia and can now be found on every continent.

Learn more about Cucumis Sativus Fruit Extract

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin

We don't have a description for Glyceryl Polymethacrylate yet.

Emulsifying, Skin Conditioning, Solvent

Hexylene Glycol is a surfactant. Glycols are a class of alcohols. Hexylene Glycol is a surfactant and emulsifier.

As a surfactant, Hexylene Glycol helps gather dirt and oil on your skin to be washed away.

As an emulsifier, Hexylene Glycol helps keep water and oil together. This prevents them from separating in a product. Hexylene Glycol also thins out the texture of a product by lessening viscosity.

Hexylene Glycol has a small molecular weight.

Learn more about Hexylene Glycol
Skin Conditioning

Palmitoyl Hexapeptide-12 is a synthetic peptide made with glycine, histidine, lysine, and palmitic acid.

The sequence of this peptide matches that of elastin, a key protein that plays a role in how firm our skin is.

Due to its palmitic acid base, this ingredient may not be fungal-acne safe.

Learn more about Palmitoyl Hexapeptide-12
Skin Conditioning

Palmitoyl Tetrapeptide-7 is a lab-made peptide with anti-inflammatory and skin-repairing benefits. It's made up of four amino acids (glycine, glutamine, proline, and arginine) and palmitic acid (which helps it penetrate skin more effectively).

This ingredient helps reduce inflammation by limiting the production of interleukin-6 (IL-6), a chemical that triggers inflammatory responses, particularly after UV exposure.

Less inflammation = slower collagen breakdown and a longer-lasting, youthful appearance.

Palmitoyl Tetrapeptide-7 also stimulates collagen production and supports a healthier skin barrier.

Over time, this can improve skin firmness, hydration, and reduce the appearance of fine lines. It’s commonly paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.

This ingredient has been shown to be effective and safe in cosmetic use and you'll typically find it in small amounts (less than 0.01%).

Due to its palmitic acid base, it may not be safe for Malassezia folliculitis.

Read more about other common types of peptides here:

Learn more about Palmitoyl Tetrapeptide-7
Skin Conditioning

Palmitoyl Tripeptide-1 is also known as pal-GHK. It is made up of 3 amino acids and palmitic acid, a fatty acid that helps it absorb into skin more easily.

This peptide is as a signal peptide, meaning it tells the skin to produce more collagen. Collagen is the key protein that helps form the skin's structure and keep it plump, firm, and hydrated.

By boosting collagen production, this ingredient supports a stronger skin barrier and helps reduce the appearance of wrinkles.

You'll most likely see this ingredient paired with Palmitoyl Tetrapeptide-7 in the well-known Matrixyl 3000 complex. While results from in-house testing should be viewed cautiously, this peptide duo is among the most studied and widely used in modern skincare.

Due to its palmitic acid base, this ingredient may not be safe for Malassezia folliculitis.

Read more about other common types of peptides here:

Learn more about Palmitoyl Tripeptide-1
Humectant, Solvent

PEG-8 is a synthetic polymer used as a humectant and solvent.

This ingredient is able to help dissolve active ingredients, including water. This gives it humectant properties.

It is soluble in water. The number '8' stands for the molecular weight of the ingredient.

Learn more about PEG-8
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Emulsifying

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.

Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.

The lauric acid used to create Polysorbate 20 is often derived from coconuts.

Polysorbate 20 may not be fungal acne safe.

Learn more about Polysorbate 20
Preservative

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Learn more about Potassium Sorbate
Skin Conditioning, Tonic

We don't have a description for Sigesbeckia Orientalis Extract yet.

Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Antioxidant, Skin Conditioning

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

When to use

55 Routines
35% use in am
65% use in pm
85% use every day
When to use See routines that use it ->
5 Routines
40% use in am
60% use in pm
100% use every day

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