Mille Collagen Vitamin+ UV Watery Sunscreen Serum SPF 50+

Mille Collagen Vitamin+ UV Watery Sunscreen Serum SPF 50+

This hybrid sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50.

Worth noting

Contains a retinoid, which is best introduced gradually.

We independently verify ingredients, backed by peer-reviewed research. Suggest an update.

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What's inside

Ingredients List

11
26
11

Water

Skin Conditioning

Ethylhexyl Methoxycinnamate

UV Absorber
0 / 0 UV Protection IconChemical UV Filter IconMay cause irritation IconNon-Reef-Safe Icon

Homosalate

Skin Conditioning
UV Protection IconChemical UV Filter IconNon-Reef-Safe Icon

Alcohol Denat.

Antimicrobial
Alcohol IconCan worsen Dry Skin IconMay worsen Eczema IconMay cause irritation IconMay worsen Rosacea Icon

Zinc Oxide

Cosmetic Colorant
1 / 0 UV Protection IconMineral UV Filter IconGood for Oily Skin IconNon-Reef-Safe Icon

Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine

Skin Conditioning
UV Protection IconChemical UV Filter Icon

Acrylates Copolymer

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin IconGood for Barrier Repair Icon

Dibutyl Adipate

Emollient

Butyloctyl Salicylate

Skin Conditioning
Non-Reef-Safe Icon

Phenethyl Benzoate

Emollient
Fragrance Icon

Caprylic/Capric Triglyceride

Masking
Coconut Derived IconHelps hydrate Dry Skin IconGood for Barrier Repair Icon

Hexyl Laurate

Emollient
Not safe for Fungal Acne Icon

Methyl Methacrylate Crosspolymer

Good for Oily Skin Icon

Silica

Abrasive
Exfoliant IconGood for Oily Skin IconGood for Minimizing Pores Icon

Pentylene Glycol

Skin Conditioning
Good for Barrier Repair Icon

Polymethylsilsesquioxane

Silicon Icon

Ceteareth-20

Cleansing
2 / 3

Sodium Acryloyldimethyltaurate Crosspolymer

Emulsion Stabilising

Caprylyl Glycol

Emollient
Fatty Alcohol Icon

Polyhydroxystearic Acid

Emulsifying
Not safe for Fungal Acne Icon

Isohexadecane

Emollient

Triethoxycaprylylsilane

Silicon Icon

Glyceryl Caprylate

Emollient

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Parfum

Masking
Synthetic Fragrance IconFragrance IconMay worsen Eczema IconMay worsen Rosacea Icon

Polysorbate 80

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Sorbitan Oleate

Emulsifying
3 / 0 Bad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Disodium EDTA

Methoxy PEG-114/Polyepsilon Caprolactone

Buffering

Hydrolyzed Collagen

Emollient
Helps with Anti-Aging IconHelps hydrate Dry Skin Icon

Snail Secretion Filtrate

Skin Conditioning
Snail Mucin IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps reduce Skin Redness IconGood for Scar Healing IconGood for Barrier Repair Icon

Rosa Damascena Flower Water

Masking
Helps reduce irritation IconHelps reduce Skin Redness Icon

Phospholipids

Skin Conditioning
Helps hydrate Dry Skin IconGood for Barrier Repair Icon

Leuconostoc/Radish Root Ferment Filtrate

Antimicrobial
Not safe for Fungal Acne Icon

Phenoxyethanol

Preservative
Preservative Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant IconHelps brighten skin Icon

Retinyl Palmitate

Skin Conditioning
1-3 / 1-3 Retinoid IconHelps brighten skin IconGood for Scar Healing IconGood for Dark Spots IconNot safe for Fungal Acne Icon

Ascorbyl Palmitate

Antioxidant
2 / 0 Vitamin C IconAntioxidant IconHelps brighten skin IconGood for Scar Healing IconNot safe for Fungal Acne Icon

Pantothenic Acid

Skin Conditioning

Cholecalciferol

Cholecalciferol PEG-12 Ether

Skin Conditioning

Angelica Keiskei Leaf/Stem Extract

Skin Conditioning

Hordeum Vulgare Seed Extract

Skin Conditioning

Oryza Sativa Extract

Absorbent
Helps with Anti-Aging IconHelps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots Icon

Aloe Barbadensis Leaf Extract

Emollient
Helps hydrate Dry Skin IconHelps reduce irritation IconHelps reduce Skin Redness Icon

Apium Graveolens Extract

Skin Conditioning

Ethylhexylglycerin

Skin Conditioning

Key Ingredients

Benefits

Concerns

Ingredients Explained

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Learn more about Water
UV Absorber, UV Filter

This ingredient is also known as Octinoxate and is one of the oldest and most widely used chemical UV filters in skincare.

It has a simple job: soap up UVB radiation (290-320 nm), the wavelengths responsible for sunburn and a big chunk of long-term sun damage.

In formulas, it's always paired with a separate UVA filter because octinoxate solely protects skin from UVB.

Because it's an oil-soluble liquid, it's easy to blend into the oil phase of lotions/creams and gives a cosmetically elegant feel.

The one quirk about formulating this ingredient is photostability; the molecule slowly changes shape into a less effective version when sunlight hits it. So the longer you're in the sun, the weaker its protection gets. The drop can be more than 30% in some formulas.

It also doesn't play nice with Avobenzone (the common UVA filter) since avobenzone destabilizes octinoxate and the two degrade each other. But don't worry: brands have solved this issue by adding photostabilizers like Tinosorb S to prevent degradation and keep SPF stable under heavy UV exposure.

The maximum allowed level is 10% in the EU and Australia, 7.5% in the US and Canada, and 20% in Japan.

The Cosmetic Ingredient Review Panel has concluded this ingredient to be safe in cosmetics up to 10%.

One last thing worth knowing for context:

Octinoxate has been the subject of ongoing review in Europe where the Scientific Committee on Consumer Safety's (SCCS) 2025 final opinion is that this ingredient is an endocrine-active substance.

Lab and animal studies suggest it can act a bit like a hormone in the body (mildly mimicking estrogen and slightly blocking male hormones). It's important to know this hasn't really been shown to happen in everyday human use.

This ingredient is also banned in Hawaii over coral reef concerns.

Learn more about Ethylhexyl Methoxycinnamate
Skin Conditioning, UV Absorber, UV Filter

Homosalate is an oil-soluble organic UVB filter that has been a sunscreen staple for decades. Its job is to absorb UVB rays (~295-315 nm) and protect your skin against sunburn,

This is one of the more photostable organic UV filters; it holds up pretty well under UV and a 2022 quantum-chemistry study found it stays stable in sunlight.

It's actually so reliable that formulators often pair it with shakier ingredients like oxybenzone and avobenzone. Formulators also use it to help dissolve the other UV filters into the oil phase.

One thing to keep in mind: "stable" isn't the same as "strong". On its own, homosalate is actually a pretty weak UV filter so it's better off as a helpful team player that helps boost overall SPF protection.

The safety picture is a bit nuanced but not scary.

This ingredient has a long track record of being gentle and regulators agree it isn't an irritant; EU's Scientific Committee on Consumer Safety found that homosalate is not considered a skin irritant and doesn't raise eye-irritation flags either.

There's talk about homosalate because your skin absorbs a little bit of it into your bloodstream. A 2020 FDA-backed study found homosalate showed up in people's blood levels at the level where the FDA decides to double check.

The EU's Scientific Committee on Consumer Safety (SCCS) also found small amounts in blood and breast milk. They estimated that about 5% of what you apply gets absorbed through the skin.

Due to the debate about whether it might mess with hormones, the SCCS recommended a maximum limit of 0.5% in most products of 7.3% in face creams/pump sprays.

One important thing to keep in mind: in the US, Homosalate is currently labeled "non-GRASE" by the FDA. This sounds alarming but really just means the FDA wants more data to confirm it's safe. It's not confidently saying this ingredient is harmful.

As of now, homosalate is still completely legal and widely used while that research gets done.

The current maximum limits are:

Learn more about Homosalate
Antimicrobial, Astringent, Masking

Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.

The "denat" part just means "denatured"; common denaturants include Denatonium Benzoate, t-butyl alcohol, and Diethyl Phthalate. This step makes the alcohol undrinkable (and lets brand skip taxes related to beverage alcohol).

This ingredient gets a bad rep because it is irritating and drying due to its astringent property. Astringents draw out natural oils in tissue to constrict pores and dry out your skin.

However, alcohol denat. is not all that bad.

Due to its low molecular weight, alcohol denat. tends to evaporate quickly. One study on pig skin found half of applied alcohol evaporated in 10 seconds and less than 3% stayed on skin.

This also helps other ingredients become better absorbed upon application.

Studies are conflicted about whether this ingredient causes skin dehydration. One study from 2005 found adding emollients to propanol-based sanitizer decreased skin dryness and irritation. Another study found irritation only occurs if your skin is already damaged.

Small amounts of alcohol are generally tolerated by oily skin or people who live in humid environments.

The rule of thumb is this ingredient will probably not affect your skin much if it is near the end of an ingredients list.

One thing to note:
People with ALDH2 (aldehyde dehydrogenase 2) deficiency may experience skin irritation from continued alcohol use. About 8% of the world's population have this deficiency.

The Cosmetic Ingredient Review Expert Panel has determined denatured alcohols to be safe for use in concentrations between 0.05% and 12% (depending on which denaturant is used).

Also...

This ingredient has antimicrobial and solvent properties.

The antimicrobial property helps preserve products and increase their shelf life. As a solvent, it helps dissolve other ingredients.

Look for formulas that contain glycerin, hyaluronic acid, or panthenol if you want to offset any drying effect.

This ingredient will trip away your skin's natural oils/lipids that help it lock in moisture. This can worsen dryness, trigger eczema flare-ups, and aggravate rosacea.

Be sure to patch test any product with this ingredient if you have dry or sensitive skin, eczema, or rosacea.

Learn more about Alcohol Denat.
Cosmetic Colorant, Skin Protecting, UV Absorber

Zinc Oxide (ZO) is a mineral broad-spectrum UV filter and the broadest-spectrum filter recognized by the FDA. It covers everything from UVB through to long-wave UVA.

On top of sun protection, it has skin protectant and skin-soothing properties too.

Here's a myth worth busting: mineral filters are usually described as working by "reflecting" or "bouncing" UV off your skin.

That's mostly not true: when researchers actually measured it, ZO and Titanium Dioxide reflect only about 4-5% of UV (less than SPF 2 worth of protection).

The vast majority of the work (~95%) is done by absorption, similar to chemical UV filters. ZO is a semiconductor that absorbs UV photos through its energy band gap.

So the old "physical blocker vs. chemical absorber" framing is really an oversimplification.

Zinc Oxide is one of the most effective broad-spectrum UV filters out there. It protects across UVB, UVA2, and UVA1 with a flat, even absorption curve across the whole UVA-UVB range.

That uniform UVA coverage is its standout feature; titanium dioxide skews more toward UVB as its particle size drops so ZO gives more consistent and extended UVA protection.

It's also very photostable. As an inorganic oxide, ZO doesn't break down in sunlight the way some organic filters can, so it holds up over a day of wear.

This ingredient is gentle and soothing, making it go-to for sunscreens aimed at sensitive skin, rosacea, or ecezma-prone skin, babies, and children.

It's also unlikely to cause the "eye sting" that some sunscreen ingredients are known for, and regulatory agencies broadly consider it non-toxic and safe for topical use.

Beyond sun protection, ZO is also a recognized OTC skin protectant. It forms a breathable barrier that shields skin from moisture and irritation while supporting healing. This is why you'll see it as a classic active in diaper rash creams.

The only downside to ZO is that it can leave a visible white cast, especially on deeper skin tones. This is the main reason mineral sunscreens have historically felt less cosmetically elegant than chemical or hybrid formulas.

Zinc Oxide comes in both non-nano and nano forms. The dividing line is 100nm and anything under is classified as a nanomaterial by the EU.

The nano version scatters less visible light which cuts down white case and gives a lighter, more wearable texture.

Another thing worth understanding about formulation:

Uncoated ZO has some inherent photocatalytic activity. This just means it can generate reactive oxygen species under UV. It's exactly why cosmetic-grade ZO is almost always surface-coated; this coating suppresses that reactivity and improves how the powder disperses and feels.

A well-formulated coated ZO largely sidesteps this issue.

Zinc Oxide is commonly used anywhere from 10% up to the regulatory maximum in sunscreens (25%).

Mineral-only broad-spectrum products often land in the 15-25% range to hit higher SPF and UVA values. Keep in mind SPF performance depends heavily on particle size, dispersion, and the rest of the formula, and not just the percentage.

As an OTC skin protectant like diaper creams, ZO typically runs higher at roughly 10-40%.

This ingredient is generally easy to work with and doesn't photodegrade.

The only thing to know is that uncoated ZO can be a bit reactive in a formula.

Under UV, it can break down sensitive ingredients like other actives or UV filters. This is another reason coated versions are standard. ZO can also react with very acidic ingredients or throw off stability of some creams. A good formula will get around this with the right coatings and dispersion.

The EU's Scientific Committee on Consumer Safety has concluded that ZO nanoparticles "can be considered to not pose any risk of adverse effects in humans after application on healthy, intact or sunburnt skin".

You might hear that ZO is "toxic"; this is because an in-vitro (test tube) study suggested micronized ZO had potential phototoxicity. In vivo (human) investigations have disputed this and the results have come back reassuring.

So does ZO penetrate skin? The short answer is no, not in any way that matters.

The most relevant evidence comes from real-world human studies: in one, volunteers applied ZO nanoparticle sunscreen hourly for six hours and daily for five days. The advanced imaging showed the particles stayed on the surface and never reached the living epidermis, and no cellular toxicity was found.

Other in-vivo and ex-vivo work agree; ZO nanoparticles don't cross the stratum corneum, even on flexed, massaged, or barrier-impaired skin.

A small amount of solubilized zinc ions can dissolve off the particles and enter the upper skin. But the quantities are tiny compared to the zinc already naturally present in your body, and studies haven't found this to cause local toxicity.

The sunscreen bans you've heard of (like Hawaii's) are aimed at two chemical filters, Oxybenzone and Octinoxate. ZO itself it not banned and is often recommended instead.

So far, there's no solid evidence that any form of ZO harms reefs. It is an ongoing and active area of study, and worth keeping an eye on.

If you're traveling somewhere with these rules, a non-nano mineral sunscreen is the safe bet.

Learn more about Zinc Oxide
Skin Conditioning, UV Absorber, UV Filter

This ingredient is better known as bemotrizinol or Tinosorb S and is one of the best broad-spectrum UV filters in modern sunscreen.

It works by absorbing UV light across a whole range (280-400 nm) with peaks around 310 nm (UVB) and 340-345 nm (UVA). This means it covers UVB plus the deeper UVA wavelengths that drive photoaging and pigmentation.

Another pro?

It's exceptionally photostable, barely degrades in sunlight, and acts as a "bodyguard" for less stable filters.

That's why you'll see it paired with avobenzone or octinoxate; this team up ensures they keep working through sun exposure.

Safety reviews have been reassuring across the board. This ingredient shows low absorption through the skin, rarely irritates, and lab studies found it doesn't act like a hormone in the body (a concern that's been raised about some older sunscreen filters).

On maximum concentrations:

In 2026, the US F.D.A finally added it as an OTC sunscreen ingredient at concentrations up to 6% for adults / children 6 months and older

Learn more about Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine

Acrylates Copolymer is used as a film-forming agent and texture enhancer.

After applied, Acrylates Copolymer forms a thin film cover that helps skin feel more soft. It can help sunscreens become more water-resistant.

It is also used to make a product more thick.

Learn more about Acrylates Copolymer
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Emollient, Skin Conditioning, Solvent

Dibutyl Adipate is a lightweight, oil-soluble ester that acts as an emollient and solvent. It helps products spread more easily and leaves a soft, silky, dry-touch finish without being greasy.

You'll likely see this ingredient in sunscreens because it does a nice job dissolving UV filters and keeping them evenly distributed.

This ingredient has been found to be safe as used in cosmetics, wasn't a skin or eye irritant in clinical patch testing, and wasn't phototoxic.

In a clinical comedogenicity test, this ingredient tested negative so it isn't likely to clog pores.

Typical use levels are about 5-8% for sunscreens + nail products, but can range from 0.005%-8% depending on the product.

Learn more about Dibutyl Adipate
Skin Conditioning, Solvent, UV Filter

Butyloctyl Salicylate is a chemical UV filter structurally similar to octisalate. It is a photostabilizer, SPF booster, emollient and solvent. This ingredient helps evenly spread out ingredients.

According to a manufacturer, it is suitable for pairing with micro Titanium Dioxide, Zinc Oxide, and pigments.

Photostabilizers help stabilize UV-filters and prevents them from degrading quickly.

Learn more about Butyloctyl Salicylate
Emollient, Perfuming

Phenethyl Benzoate is a fragrance.

Masking, Skin Conditioning

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Learn more about Caprylic/Capric Triglyceride
Emollient, Skin Conditioning

Hexyl Laurate isn't fungal acne safe.

This ingredient comes as a powder made up of small, porous, microbeads. It is used to add a silky feel to products and also helps absorb oil.

Abrasive, Absorbent

Silica, also known as silicon dioxide, is a naturally occurring mineral. It is used as a fine, spherical, and porous powder in cosmetics.

Though it has exfoliant properties, the function of silica varies depending on the product.

The unique structure of silica enhances the spreadability and adds smoothness, making it a great texture enhancer.

It is also used as an active carrier, emulsifier, and mattifier due to its ability to absorb excess oil.

In some products, tiny microneedles called spicules are made from silica or hydrolyzed sponge. When you rub them in, they lightly polish away dead skin layers and enhance the penetration of active ingredients.

Learn more about Silica
Skin Conditioning, Solvent

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Learn more about Pentylene Glycol

Polymethylsilsesquioxane is a silicone used as a film forming agent.

When applied to the skin, this ingredient creates an invisible film on the surface. This film still allows oxygen to pass through, but prevents moisture from escaping. This can help condition and hydrate the skin. It also leaves a silky feel when applied.

Polymethylsilsesquioxane has not been shown to clog pores. It has been deemed safe to use up to 55%, but most cosmetics use much less.

If you have concerns about using this ingredient, we recommend speaking with a professional.

Learn more about Polymethylsilsesquioxane
Cleansing, Emulsifying, Surfactant

Ceteareth-20 is an emulsifier and surfactant made by reacting cetearyl alcohol with 20 moles of ethylene oxide.

This gives it both oil and water-loving properties that makes it an effect emulsifier; it's really great at pulling oil droplets into water to create a stable, creamy, and easy-to-spread base.

Typical use ranges from 0.5-30%. Most leave-on products are in the 1-10% zone.

The 20 ethylene oxide units is well above the PEG-10 threshold and therefore not a food source for Malassezia (it's fungal acne safe).

This ingredient has a comedogenic rating of 2 and an irritancy rating of 3. These numbers come from testing the raw ingredient on rabbit ears and doesn't reflect how it will behave in a finished product.

In practice, this ingredient is a well-tolerated ingredient. The ratings reflect cautious lab conditions and not real-world use. Just be sure to patch test any formulas you feel unsure about.

Learn more about Ceteareth-20

We don't have a description for Sodium Acryloyldimethyltaurate Crosspolymer yet.

Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Learn more about Caprylyl Glycol

Polyhydroxystearic Acid is a vegetable-derived soft wax made from castor oil. It's an emulsion stabilizer, thickener, and film former.

You'll likely see it in sunscreens because it helps disperse pigments and UV-reflecting minerals like titanium dioxide and zinc oxide evenly.

Depending on the concentration, it can drastically change the texture of a product from pasty solid (like lipstick) to sprayable liquid.

The CIR Expert Panel for Cosmetic Ingredient Safety has concluded this ingredient to be safe in cosmetics. The highest reported use concentration is 14.2% in lipsticks.

Learn more about Polyhydroxystearic Acid
Emollient, Skin Conditioning, Solvent

Isohexadecane is added to enhance texture, emulsify, and to help cleanse. It is an isoparrafin. It is a component of petrolatum.

Due to its large size, Isohexadecane is not absorbed by the skin. Instead, it sits on top and acts as an emollient. Emollients help keep your skin soft and smooth by trapping moisture within.

Isohexadecane is often used in products designed to help oily skin. It is lightweight and non-greasy while helping to moisturize. When mixed with silicones, it gives a product a silky feel.

Learn more about Isohexadecane

Triethoxycaprylylsilane is a silicon-based surface modifier that makes sunscreens feel silky and makeup stay put.

Its main job is to coat mineral particles like titanium dioxide, zinc oxide, and color pigments in a thin, oily layer so they spread smoothly, don't clump, and stick to skin better.

This ingredient is typically used at low levels (up to 2.5% in eyeshadow and 1% in lipstick).

Learn more about Triethoxycaprylylsilane
Emollient, Emulsifying

Glyceryl Caprylate comes from glycerin and caprylic acid. It is an emollient, co-emulsifier, and preservative booster.

Its short C8 fatty acid chain makes it behave differently from its longer-chain emollient cousins like Glyceryl Stearate. It feels more lightweight, fast-absorbing, and silky instead of rich and waxy.

As a co-emulsifier, its "head" and "tail" sit at the oil-water interface. But overall, the short C8 tail and not being water soluble means it doesn't really have the muscle to emulsify a formula on its own. That's why you'll often see it paired with a primary emulsifier like Cetearyl Glucoside.

Interestingly, Glyceryl Caprylate acts as a preservative booster. This is because its fatty-acid backbone disrupts microbial lipid membranes. It shows excellent activity against bacteria and yeast but is weaker against mold.

Typical concentrations range from 0.5-1% and this ingredient is generally non-irritating.

Because this ingredient has a C8 fatty acid chain, it is outside the range that the Malassezia yeast metabolizes (making it fungal acne safe).

Learn more about Glyceryl Caprylate

Ammonium Acryloyldimethyltaurate/Vp Copolymer is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.

Think of it as a supportive ingredient that helps your gel-creams feel silky, "cloud cream-like", and spread evenly without being greasy.

The Cosmetic Ingredient Review (CIR) Expert Panel evaluated it (along with 22 other acryloyldimethyltaurate polymers) and concluded it's:

Due to its large molecular size, it sits on the surface of skin rather than penetrating it.

Learn more about Ammonium Acryloyldimethyltaurate/Vp Copolymer
Masking, Perfuming

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.

For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.

The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.

For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.

One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.

Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.

Parfum can also be used to mask or cover an unpleasant scent.

The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.

Learn more about Parfum
Emulsifying, Surfactant

Polysorbate 80 is a synthetic surfactant and emulsifier derived from sorbitol and oleic acid.

It reduces the surface tension between oil and water phases to help them stay mixed and stable in a formulation. In other words, it prevents your formulas from separating into an oily mess.

The CIR Expert Panel has evaluated the scientific data and found this ingredient to be safe, non-irritating, and non-sensitizing at concentrations up to 5% (it's even approved by the FDA as an OTC eye drop ingredient).

Learn more about Polysorbate 80
Emulsifying

Sorbitan Oleate is a PEG-free emulsifier made by esterifying sorbitol with oleic acid.

You'll likely see it paired with Polysorbate 80 to create the right emulsification balance.

Typical use levels in formulas range from 2-10%.

The CIR Expert Panel has concluded this ingredient to be safe as a cosmetic ingredient.

Since this ingredient is an ester of oleic acid, it may not be fungal acne safe. Oleic acid is a fatty acid that falls into the C11-24 range that Malassezia can metabolize.

Learn more about Sorbitan Oleate

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Learn more about Disodium EDTA

We don't have a description for Methoxy PEG-114/Polyepsilon Caprolactone yet.

Emollient, Humectant, Skin Conditioning

Hydrolyzed Collagen is Collagen (usually sourced from fish, bovine, or porcine byproducts) that's been broken down into smaller peptides. This makes it water-soluble and easy to blend into formulations.

In a formula, it works mainly as a skin-conditioning and moisturizing agent.

The small peptides and amino acids (including Natural Moisturizing Factor components like Hydroxyproline, Serine, and Aspartic Acid) help the surface of the skin hold onto water, feel softer, and look temporarily plumper.

This ingredient also has mild film-forming and antioxidant properties with research showing the antioxidant effect is stronger the lower the molecular weight of the peptides.

It's worth being realistic here:

Topically applied Hydrolyzed Collagen conditions the upper layers of skin rather than rebuilding the structural collagen deep in your dermis (the wrinkle-and-firmness benefits people associate with Collagen mostly come from oral supplements in studies, not topicals).

However, recent lab and skin-model work on Hydrolyzed Fish Collagen has shown promising effects on cell viability and wound healing when used as an active.

Typical concentrations range from 0.2-2%, but the percentage can go much higher in rinse-off or hair products (sometimes even above 50%).

Clinical studies on this ingredient showed no irritation, sensitization, or phototoxicity.

If you are looking for vegan collagen, it usually goes by a different INCI name like hydrolyzed soy protein. Vegan collagen is derived from yeast, bacteria, or plant sources.

The results are varied.

A study from 2021 found hydrolyzed collagen increased elasticity and improved wrinkles in 1,125 participants between age 20 and 70. Another study found increased skin thickness in participants between the ages of 45 to 59.

However, It is difficult to prove that oral collagen will end up working on your skin. Many of the studies using hydrolyzed collagen also add several vitamins and nutrients into the test mixture as well.

Further studies are needed at this time.

Learn more about Hydrolyzed Collagen
Skin Conditioning

Snail Secretion Filtrate (the slimy mucus that garden snails produce) is a multitasking ingredient that shows up in "skin repair" formulas.

This ingredient works because it's a grab bag of skin-friendly stuff like:

In a formula, it acts as a humectant and barrier-supporting soother and the research backs this up as well.

A 2025 systematic review of human clinical trials found that snail-derived ingredients improved signs of aging, increased skin hydration, decreased transepidermal water loss, and improved healing after radiation therapy/fractional laser treatment.

Lab studies have also shown the secretion promotes the proliferation, migration, and survival of the cells that rebuild skin (keratinocytes and dermal fibroblasts).

There's also a placebo-controlled study where a serum containing it helped with mask-related acne.

Overall, this is a gentle, water-based multitasker that works great for hydrating and supporting the skin barrier. However, please see the section below if you have dust mite or shellfish allergies.

You'll see snail filtrate listed at very different percentages depending on the product. Some Korean serums list it near the top of the ingredients at 90% or more while other products use just a few percent.

This doesn't mean the high-percentage ones are far stronger. Raw snail filtrate is mostly water to begin with so using a lot of it isn't the same thing as using a lot of the active ingredients.

Other products use a concentrated version so a small amount goes a long way. Either approach can work well. Just know the percentage on the label isn't a reliable way to judge how effective a snail product will be.

Being cruelty-free means a brand does not experiment on animals. If you're worried about the well-being of the snails, we recommend looking more into the company of the product. Many brands claim to have developed humane methods to collect snail mucin.

There is much debate on this subject. On one hand, this ingredient comes from an animal. On the other hand, many will argue the ingredient is naturally secreted (like a natural by-product) and therefore vegan. If you have reservations, you can look into Galactomyces Ferment Filtrate or Centella Asiatica Extract as alternatives.

This ingredient is fungal acne safe. Its core composition lacks the fatty acid/ester triggers that Malassezia depends on.

True allergy to Snail Secretion Filtrate is uncommon and most documented cases are linked to a dust mite allergy.

Snail proteins (including Tropomyosin) are similar enough to dust mite proteins that the immune system can confuse them.

In most documented cases, the dust mite was the original trigger and tropomyosin turned out to be only a minor player in some studies (so this has not been fully confirmed).

Another thing to know is that nearly all the evidence comes from eating snails or inhaling the protein and not from cosmetics.

However, the allergenic proteins can survive filtration into a finished product; a topical reaction is biologically plausible but there's little published evidence of it actually happening.

People who are allergic to dust mites (or sometimes shellfish) are the most likely to react.

Learn more about Snail Secretion Filtrate
Masking, Skin Conditioning, Skin Protecting

Rosa Damascena Flower Water is the water-based byproduct of steam-distilling damask rose petals. It has skin conditioning, masking, and skin protecting properties.

Research shows that Rosa damascena is rich in flavonoids and phenolic compounds like gallic acid that contribute to its antioxidant activity.

In vitro studies have shown that Rosa damascena can scavenge free radicals and reduce melanin overproduction. Research has also found this extract offers some degree of UV absorption but this should not replace your sunscreen.

Learn more about Rosa Damascena Flower Water
Skin Conditioning

Phospholipids are a family of skin-identical lipids that makeup the structural backbone of every cell membrane in your body.

In cosmetics, they function as skin conditioning agents with emulsifier and surfactant properties. They're typically sourced from soybean or sunflower lecithin (or sometimes egg yolk or marine sources).

Because they mirror the lipids naturally found in the deeper layers of your skin, topical phospholipids help reinforce the lipid matrix, reduce transepidermal water loss, and leave skin feeling conditioned.

They're also used to form liposomes, or tiny self-assembling vesible used to stabilize actives like vitamin c or retinol. This helps these ingredients integrate into the upper layers of skin more easily.

Phospholipids are compatible with everything and the CIR Expert Panel has concluded them to be safe at current use levels.

Some types of phospholipids include:

Learn more about Phospholipids

Leuconostoc/Radish Root Ferment Filtrate is a natural preservative. It comes from fermenting radish roots with a bacteria called leuconostoc. The trade name for this ingredient is Leucidal.

Leuconostoc comes from lactic acid.

This ingredient has antimicrobial properties and helps prevent the growth of bacteria in a product.

Leuconostoc is used to make the traditional Korean side-dish, kimchi. It is also used to make sourdough bread (both incredibly yummy foods).

Learn more about Leuconostoc/Radish Root Ferment Filtrate
Preservative

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Learn more about Phenoxyethanol
Antioxidant, Skin Conditioning

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Learn more about Tocopheryl Acetate
Skin Conditioning

Retinyl Palmitate is a form of retinoid. Retinoids are the superstar class of anti-aging ingredients that include Tretinoin and Retinol.

This particular ingredient has had a bumpy year with its rise and fall in popularity.

First, Retinyl Palmitate is created from Palmitic Acid and Retinol. It is a Retinol ester and considered one of the weaker forms of retinoid.

This is because all retinoids have to be converted to Tretinoin, AKA Retinoic Acid.

Retinyl Palmitate is pretty far down the line and has to go through multiple conversions before its effects are seen. Once it's on your skin, enzymes called esterases convert it into Retinol, then into Retinal, and finally into Retinoic Acid; that's three steps with a little lost at each one.

The benefits of Retinyl Palmitate are debated due to this long and ineffective conversion line.

So why use it at all?

The answer is stability. Retinol and Retinoic Acid break down fast when they hit light, heat, and air, and Retinoic Acid can be pretty irritating on top of that.

Retinyl Palmitate is much more stable and gentler, making it easier to formulate with and easier on sensitive skin (even if it's weaker gram for gram).

Studies show Retinyl Palmitate to help:

Newer research from 2023-2025 also found that Retinyl Palmitate works especially well when paired with Retinol. The two seem to cover each other's weak spots; retinol brings the potency while Retinyl Palmitate brings the stability and gentleness. Together, they repair UV damage better than either one does alone.

This ingredient used to be found in sunscreens to boost the efficacy of sunscreen filters.

The downfall of Retinyl Palmitate was due to released reports about the ingredient being correlated to sun damage and skin tumors.

Most of this traces back to a 2012 US National Toxicology Program (NTP) study where hairless mice coated in Retinyl Palmitate cream and exposed to UV light developed skin tumors faster.

Here's the nuance, though.

When the Cosmetic Ingredient Review (CIR) Expert Panel went back through that study, they found methodological flaws and decided the results couldn't be interpreted as proof of extra risk.

The EU's Scientific Committee on Consumer Safety (SCCS) said the mouse findings might point to a concern but they're hard to apply to humans since hairless mouse skin and human skin behave differently.

While there is a study showing this ingredient to cause DNA damage when exposed to UVA, there is no concrete proof of it being linked to skin cancer. It is completely safe to use when used correctly.

Both the CIR and the SCCS consider it safe at the concentrations used in cosmetics; the SCCS specifically cleared retinoids up to 0.05% in body lotions and 0.3% in face creams, hand creams, and rinse-off products.

As of 2025, the EU has written those limits into law, plus a label warning about your total Vitamin A intake from all sources.

All retinoids increase your skin's sensitivity to the sun in the first few months of usage. Be especially careful with reapplying sunscreen when using any form of retinoid.

One more note: if you're pregnant, high doses of Vitamin A can be a concern, so a lot of people skip topical retinoids (including Retinyl Palmitate) during pregnancy just to be safe. Check with your doctor if you're unsure.

Fun fact: This ingredient is often added to low-fat milk to increase the levels of Vitamin A.

Learn more about Retinyl Palmitate
Antioxidant, Masking

Ascorbyl Palmitate is a fat-soluble form of vitamin C (Ascorbic Acid) made by combining it with palmitic acid.

It is able to blend easily into creams and oil-based formulas because it dissolves in oils rather than water.

As you may know, regular vitamin C is notorious for breaking down when exposed to sunlight and air. Ascorbyl Palmitate is more stable and degrades at a slower rate.

Research on whether it converts efficiently into active vitamin C once it's applied on your skin is still limited.

Some in-vitro studies suggest it may support collagen production, but it is not considered one of the stronger vitamin C derivatives, like:

Due to the palmitic acid base, this ingredient may not be fungal acne safe. Comedogenic studies have also shown this ingredient to have a rating of 2.

It's also worth keeping in mind that comedogenic and irritancy ratings are tested on individual ingredients, not finished formulas. The final product's formulation, concentration, and other ingredients all play a role in how something actually behaves on your skin.

Learn more about Ascorbyl Palmitate
Skin Conditioning

Pantothenic Acid is also known as Vitamin B5. It is a water-soluble vitamin with skin hydrating and soothing properties.

Research shows pantothenic acid help support the skin's natural barrier by improving moisture retention. This is why you'll likely find this ingredient in soothing products or formulations for sensitive skin.

Some studies have explored oral supplementation of pantothenic acid in the acne context and found it to help reduce blemishes over time.

Though oral and topical use are different, this research helps explain why vitamin B5 is often included in skincare routines aimed at keeping skin balanced and hydrated.

Learn more about Pantothenic Acid

Cholecalciferol is also known as vitamin D3. It has skin conditioning properties.

Skin Conditioning

Cholecalciferol is a form of vitamin D.

The PEG stands for polyethylene glycol and ether refers to a condensation of alcohols.

We don't have a description for Angelica Keiskei Leaf/Stem Extract yet.

Skin Conditioning

We don't have a description for Hordeum Vulgare Seed Extract yet.

Absorbent, Skin Conditioning

Oryza Sativa Extract comes from the rice grain, Oryza sativa. Rice extract has wound healing, antioxidant, anti-inflammatory, and hydrating properties.

Rice grains contain numerous antioxidants which may help with anti-aging, such as vitamin E. Antioxidants help stabilize free-radical molecules. Unstable free-radical molecules may damage your skin cells and accelerate signs of aging.

A study from 2002 found rice to help increase the rate of wound healing. The same study found an improvement of skin barrier function in the patients after taking rice baths.

Numerous in-vitro studies have found rice water to help decrease sun damage by increasing collagen production and inhibiting the process of tyrosinase.

Long story short- tyrosinase is an enzyme that controls melanin production. Our bodies start producing melanin (AKA tanning) when exposed to UV radiation to protect against damage. Rice water is found to partially block this process.

Though more research is needed on rice's ability to help with UV protection, recent studies seem promising.

Wondering why rice is hydrating? The protein in rice have emollient properties. Emollients create a barrier on the skin to trap moisture in, keeping your skin moisturized.

Some rice extract may have mildly-exfoliating properties. These are mainly limited to Oryza Sativa (Rice) Bran and Oryza Sativa (Rice) Germ Powder.

This rice was first cultivated in China over 10,000 years ago. Many cultures throughout Asia have used rice water on skin and hair for centuries.

Learn more about Oryza Sativa Extract
Emollient, Humectant, Skin Conditioning

Aloe Barbadensis Leaf Extract is a botanical extract pulled from the leaves of aloe vera and one of the most studied plant ingredients in cosmetics.

The inner leaf gel it comes from is mostly water (~99-99.5%) and the remaining fraction is made up of pretty good stuff: polysaccharides, vitamins, phenolics, and enzymes.

Its headline job is hydration.

The star polysaccharide in aloe, acemannan, is a humectant that retains moisture and helps reduce trans-epidermal water loss.

Aloe also has real soothing credentials; it contains anti-inflammatory compounds like bradykinase and C-glucosyl chromone that help calm irritation and redness.

On the repair side, lab work shows that acemannan wakes up your skin's repair cells (fibroblasts), prompting them to multiply and speed up healing.

There's some human data for cosmetic benefit too: a cream containing 10% Aloe Barbadensis leaf extract improved skin hydration and elasticity in a real-use study.

Safety-wise, this ingredient is well-regarded with just one rare downside; there have been some case reports of acute eczema, contact urticaria, and dermatitis in people who applied aloe-derived ingredients topically. Those with a known aloe or Liliaceae sensitivity should patch test.

Typical use levels range widely, from under 1% up to 90%+ depending on the format and the effect you are after.

Learn more about Aloe Barbadensis Leaf Extract
Skin Conditioning

Apium Graveolens Extract is derived from celery. It contains antioxidants such as Ferulic Acid and Caffeic Acid.

Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells

Skin Conditioning

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Learn more about Ethylhexylglycerin

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Where it's from

Mille is a Thai brand

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50 SPF Rating

With an SPF rating of 50, this product protects against 98.0% of UVB rays

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· Updated September 7, 2025 Added by marisollarkin