Theramid Derma-Peptides 35% Versus Numbuzin No.9 NAD+ PDRN Glow Boosting Toner
Updated on July 16, 2025
Overview
What they are
These products are both cruelty-free and reef safe . They have a total of 21 ingredients in common
Cool Features
They both contain AHA, peptides and Vitamin E
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any common allergens, parabens, silicones or sulfates
What's Inside
They both contain fragrances
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Theramid Derma-Peptides 35% 46 ingredients
Numbuzin No.9 NAD+ PDRN Glow Boosting Toner 125 ingredients
What's inside
What's inside
At a glance
Click on any of the items below to learn more
Theramid Derma-Peptides 35% 46 ingredients
Numbuzin No.9 NAD+ PDRN Glow Boosting Toner 125 ingredients
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
Humectant
Propanediol
Solvent
Caprylic/Capric Triglyceride
Masking
Butylene Glycol
Humectant
Dodecane
Perfuming
C15-19 Alkane
SolventHordeum Vulgare Seed Flour
Abrasive
Ethyl Macadamiate
Skin Conditioning
Glycine Soja Seed Extract
Skin Conditioning
Sodium Hyaluronate
Humectant
Acetyl Hexapeptide-1
Skin Conditioning
N-Prolyl Palmitoyl Tripeptide-56 Acetate
Skin Conditioning
Acetyl Tetrapeptide-2
Skin Conditioning
Palmitoyl Tripeptide-38
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Sh-Oligopeptide-1
Skin Conditioning
Sh-Oligopeptide-2
Skin Conditioning
Sh-Polypeptide-1
Skin Conditioning
Sh-Polypeptide-11
Sh-Polypeptide-9
Skin Conditioning
Palmitoyl Dipeptide-10
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Nonapeptide-1
Skin Conditioning
Acetyl Glutamine
Skin ConditioningBacillus/Folic Acid Ferment Filtrate Extract
Antioxidant
Tocopherol
Antioxidant
Polyacrylate-13
Pullulan
Polyisobutene
Silica
Abrasive
Pentylene Glycol
Skin ConditioningPolysorbate 20
Emulsifying
1,2-Hexanediol
Skin Conditioning
Lecithin
Emollient
Sorbitan Isostearate
Emulsifying
Carbomer
Emulsion StabilisingSclerotium Gum
Emulsion StabilisingXanthan Gum
EmulsifyingSodium Lactate
BufferingHydroxypropyl Cyclodextrin
MaskingMalic Acid
Buffering
Dextran
Caprylyl Glycol
Emollient
Ethylhexylglycerin
Skin ConditioningPhenoxyethanol
Preservative
Water, Glycerin, Propanediol, Caprylic/Capric Triglyceride, Butylene Glycol, Dodecane, C15-19 Alkane, Hordeum Vulgare Seed Flour, Ethyl Macadamiate, Glycine Soja Seed Extract, Sodium Hyaluronate, Acetyl Hexapeptide-1, N-Prolyl Palmitoyl Tripeptide-56 Acetate, Acetyl Tetrapeptide-2, Palmitoyl Tripeptide-38, Palmitoyl Tripeptide-1, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-11, Sh-Polypeptide-9, Palmitoyl Dipeptide-10, Palmitoyl Tetrapeptide-7, Nonapeptide-1, Acetyl Glutamine, Bacillus/Folic Acid Ferment Filtrate Extract, Tocopherol, Polyacrylate-13, Pullulan, Polyisobutene, Silica, Pentylene Glycol, Polysorbate 20, 1,2-Hexanediol, Lecithin, Sorbitan Isostearate, Carbomer, Sclerotium Gum, Xanthan Gum, Sodium Lactate, Hydroxypropyl Cyclodextrin, Malic Acid, Dextran, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol
Water
Skin ConditioningMethylpropanediol
SolventNiacinamide
Smoothing
PEG/PPG-17/6 Copolymer
SolventPropanediol
Solvent
1,2-Hexanediol
Skin Conditioning
Tripropylene Glycol
Antioxidant
Glyceryl Glucoside
Humectant
Xylitylglucoside
Humectant
PEG-40 Hydrogenated Castor Oil
Emulsifying
Anhydroxylitol
Humectant
Glycerin
Humectant
Polyglyceryl-10 Laurate
Skin Conditioning
Candida Bombicola/Glucose/Methyl Rapeseedate Ferment
AntimicrobialC20-40 Pareth-10
EmulsifyingTocopheryl Acetate
Antioxidant
Xylitol
Humectant
Cetearyl Alcohol
Emollient
Sodium Dna
Skin Conditioning
Hydrogenated Lecithin
Emulsifying
Glucose
Humectant
Polyacrylate Crosspolymer-6
Emulsion StabilisingEthylhexylglycerin
Skin ConditioningAdenosine
Skin Conditioning
Ceramide NP
Skin Conditioning
Sodium Phytate
Helianthus Annuus Seed Oil
Emollient
Melia Azadirachta Leaf Extract
Skin ConditioningMelia Azadirachta Flower Extract
Skin ConditioningCitric Acid
Buffering
Hydroxyethylcellulose
Emulsion StabilisingSodium Citrate
BufferingPhytosterols
Skin Conditioning
Coccinia Indica Fruit Extract
Skin ConditioningAloe Barbadensis Flower Extract
EmollientSolanum Melongena Fruit Extract
Skin ConditioningT-Butyl Alcohol
Perfuming
Ocimum Sanctum Leaf Extract
Skin Conditioning
Curcuma Longa Root Extract
Masking
Corallina Officinalis Extract
Skin Conditioning
Cyanocobalamin
Skin ConditioningCaprylic/Capric Triglyceride
Masking
Hydrolyzed Collagen
Emollient
Butylene Glycol
Humectant
Adenosine Triphosphate
Skin ConditioningNicotinamide Adenine Dinucleotide
Skin ConditioningResveratrol
Antioxidant
Pullulan
Sodium Palmitoyl Sarcosinate
CleansingPalmitic Acid
Emollient
C12-14 Alketh-12
EmulsifyingPisum Sativum Peptide
Skin Conditioning
Stearic Acid
Cleansing
Polyglyceryl-6 Laurate
Emulsifying
Caprylyl Glycol
Emollient
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning
Dextran
Hydrolyzed Elastin
EmollientSoluble Collagen
Humectant
Acetyl Tetrapeptide-3
Skin Protecting
Trifolium Pratense Flower Extract
Astringent
Disodium EDTA
Myristic Acid
Cleansing
Acetyl Hexapeptide-8
Humectant
Mannose
HumectantSh-Octapeptide-4
Antioxidant
Sh-Decapeptide-7
Antioxidant
Palmitoyl Pentapeptide-4
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Copper Tripeptide-1
Skin Conditioning
Hexapeptide-9
Skin Conditioning
Nonapeptide-1
Skin Conditioning
Tripeptide-1
Skin Conditioning
Arachidic Acid
Cleansing
Collagen
Moisturising
Elastin
Skin ConditioningGlutathione
Palmitoyl Tetrapeptide-7
Skin Conditioning
Arginine/Lysine Polypeptide
Skin Conditioning
Oligopeptide-29
Antioxidant
Oligopeptide-32
Antiseborrhoeic
Acetyl Tetrapeptide-5
Humectant
Acetyl Tetrapeptide-9
Skin Conditioning
Acetyl Tetrapeptide-2
Skin Conditioning
Acetyl Octapeptide-3
Humectant
Acetyl Hexapeptide-1
Skin Conditioning
Alanine/Histidine/Lysine Polypeptide Copper Hcl
Skin Conditioning
Acetyl Dipeptide-1 Cetyl Ester
Skin Conditioning
Acetyl Sh-Pentapeptide-1
Skin Conditioning
Biotinoyl Tripeptide-1
Dipeptide-4
Skin Conditioning
Hexapeptide-11
Skin Conditioning
Hexapeptide-12
Skin Conditioning
Lauric Acid
Cleansing
Myristoyl Pentapeptide-17
Skin Conditioning
Myristoyl Hexapeptide-16
Skin Conditioning
Myristoyl Pentapeptide-4
Skin Conditioning
Nicotinoyl Tripeptide-1
Antioxidant
Nonapeptide-7
Skin Conditioning
Nicotinoyl Tripeptide-35
Antioxidant
Nicotinoyl Dipeptide-26
Skin Conditioning
Nicotinoyl Dipeptide-23
Skin Conditioning
Octapeptide-2
Skin Conditioning
Palmitoyl Tripeptide-5
Skin Conditioning
Palmitoyl Hexapeptide-12
Skin Conditioning
Pentapeptide-13
Skin Conditioning
Palmitoyl Tetrapeptide-10
Skin Conditioning
Palmitoyl Tripeptide-38
Skin Conditioning
Palmitoyl Tripeptide-29
Skin Conditioning
Palmitoyl Tripeptide-8
Skin Conditioning
Sr-(Oligopeptide-91 Clostridium Botulinum Polypeptide-1)
Skin Conditioning
Tetrapeptide-44
Skin Conditioning
Tetrapeptide-30
Skin Conditioning
Tripeptide-10 Citrulline
Skin Conditioning
Tripeptide-32
Skin Conditioning
Tripeptide-29
Skin Conditioning
Sh-Polypeptide-22
Skin Conditioning
Sh-Oligopeptide-1
Skin Conditioning
Sh-Polypeptide-1
Skin Conditioning
Sh-Polypeptide-9
Skin Conditioning
Sh-Oligopeptide-2
Skin Conditioning
Sh-Polypeptide-11
Sh-Polypeptide-3
Skin Conditioning
Sh-Polypeptide-16
Skin Protecting
Sh-Polypeptide-62
Antioxidant
Water, Methylpropanediol, Niacinamide, PEG/PPG-17/6 Copolymer, Propanediol, 1,2-Hexanediol, Tripropylene Glycol, Glyceryl Glucoside, Xylitylglucoside, PEG-40 Hydrogenated Castor Oil, Anhydroxylitol, Glycerin, Polyglyceryl-10 Laurate, Candida Bombicola/Glucose/Methyl Rapeseedate Ferment, C20-40 Pareth-10, Tocopheryl Acetate, Xylitol, Cetearyl Alcohol, Sodium Dna, Hydrogenated Lecithin, Glucose, Polyacrylate Crosspolymer-6, Ethylhexylglycerin, Adenosine, Ceramide NP, Sodium Phytate, Helianthus Annuus Seed Oil, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Citric Acid, Hydroxyethylcellulose, Sodium Citrate, Phytosterols, Coccinia Indica Fruit Extract, Aloe Barbadensis Flower Extract, Solanum Melongena Fruit Extract, T-Butyl Alcohol, Ocimum Sanctum Leaf Extract, Curcuma Longa Root Extract, Corallina Officinalis Extract, Cyanocobalamin, Caprylic/Capric Triglyceride, Hydrolyzed Collagen, Butylene Glycol, Adenosine Triphosphate, Nicotinamide Adenine Dinucleotide, Resveratrol, Pullulan, Sodium Palmitoyl Sarcosinate, Palmitic Acid, C12-14 Alketh-12, Pisum Sativum Peptide, Stearic Acid, Polyglyceryl-6 Laurate, Caprylyl Glycol, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Dextran, Hydrolyzed Elastin, Soluble Collagen, Acetyl Tetrapeptide-3, Trifolium Pratense Flower Extract, Disodium EDTA, Myristic Acid, Acetyl Hexapeptide-8, Mannose, Sh-Octapeptide-4, Sh-Decapeptide-7, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Copper Tripeptide-1, Hexapeptide-9, Nonapeptide-1, Tripeptide-1, Arachidic Acid, Collagen, Elastin, Glutathione, Palmitoyl Tetrapeptide-7, Arginine/Lysine Polypeptide, Oligopeptide-29, Oligopeptide-32, Acetyl Tetrapeptide-5, Acetyl Tetrapeptide-9, Acetyl Tetrapeptide-2, Acetyl Octapeptide-3, Acetyl Hexapeptide-1, Alanine/Histidine/Lysine Polypeptide Copper Hcl, Acetyl Dipeptide-1 Cetyl Ester, Acetyl Sh-Pentapeptide-1, Biotinoyl Tripeptide-1, Dipeptide-4, Hexapeptide-11, Hexapeptide-12, Lauric Acid, Myristoyl Pentapeptide-17, Myristoyl Hexapeptide-16, Myristoyl Pentapeptide-4, Nicotinoyl Tripeptide-1, Nonapeptide-7, Nicotinoyl Tripeptide-35, Nicotinoyl Dipeptide-26, Nicotinoyl Dipeptide-23, Octapeptide-2, Palmitoyl Tripeptide-5, Palmitoyl Hexapeptide-12, Pentapeptide-13, Palmitoyl Tetrapeptide-10, Palmitoyl Tripeptide-38, Palmitoyl Tripeptide-29, Palmitoyl Tripeptide-8, Sr-(Oligopeptide-91 Clostridium Botulinum Polypeptide-1), Tetrapeptide-44, Tetrapeptide-30, Tripeptide-10 Citrulline, Tripeptide-32, Tripeptide-29, Sh-Polypeptide-22, Sh-Oligopeptide-1, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Oligopeptide-2, Sh-Polypeptide-11, Sh-Polypeptide-3, Sh-Polypeptide-16, Sh-Polypeptide-62
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Acetyl Hexapeptide-1 is a peptide.
This peptide is more commonly known as Thymulen 4 BG.
It is derived from a youth hormone called thymopoietin. Thymopoietin helps regulate the immune system and decreases naturally with age.
According to the manufacturer, this peptide boosts the skin's immune defenses and regenerates the outer layers of skin.
Learn more about Acetyl Tetrapeptide-2Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolThis ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.
Learn more about Caprylic/Capric TriglycerideCaprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolDextran is a sugar (polysaccharide) with skin hydrating properties.
Fun fact: Louis Pasteur first discovered this ingredient as a microbial product in wine.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinNonapeptide-1 is created from amino acids including arginine and lysine.
It has antioxidant and antimicrobial properties.
Emerging studies show Nonapeptide-1 to help with reducing pigmentation and brightening the skin. It has shown to prevent the activation of tyrosinase, an enzyme in the skin that begins the process of melanin creation. Melanin is responsible for giving skin a tan or dark spots.
Learn more about Nonapeptide-1Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a lab-made peptide with anti-inflammatory and skin-repairing benefits. It's made up of four amino acids (glycine, glutamine, proline, and arginine) and palmitic acid (which helps it penetrate skin more effectively).
This ingredient helps reduce inflammation by limiting the production of interleukin-6 (IL-6), a chemical that triggers inflammatory responses, particularly after UV exposure.
Less inflammation = slower collagen breakdown and a longer-lasting, youthful appearance.
Palmitoyl Tetrapeptide-7 also stimulates collagen production and supports a healthier skin barrier.
Over time, this can improve skin firmness, hydration, and reduce the appearance of fine lines. It’s commonly paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.
This ingredient has been shown to be effective and safe in cosmetic use and you'll typically find it in small amounts (less than 0.01%).
Due to its palmitic acid base, it may not be safe for Malassezia folliculitis.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tetrapeptide-7Palmitoyl Tripeptide-1 is also known as pal-GHK. It is made up of 3 amino acids and palmitic acid, a fatty acid that helps it absorb into skin more easily.
This peptide is as a signal peptide, meaning it tells the skin to produce more collagen. Collagen is the key protein that helps form the skin's structure and keep it plump, firm, and hydrated.
By boosting collagen production, this ingredient supports a stronger skin barrier and helps reduce the appearance of wrinkles.
You'll most likely see this ingredient paired with Palmitoyl Tetrapeptide-7 in the well-known Matrixyl 3000 complex. While results from in-house testing should be viewed cautiously, this peptide duo is among the most studied and widely used in modern skincare.
Due to its palmitic acid base, this ingredient may not be safe for Malassezia folliculitis.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tripeptide-1This synthetic, signal peptide has unique skin conditioning properties in that is a matrikine-mimetic compound.
First of all, Palmitoyl Tripeptide-38 is a signal peptide; signal peptides tell the body to create more collagen.
What is a matrikine-mimetic compound?
This peptide has the ability to mimic matrikines in skin. Our skin created matrikines by breaking down matrix proteins into peptides.
Matrikines play a role in:
Though further research is needed, this ingredient seems pretty promising. In one study, women over the age of 40 with visible photoaging used a vitamin C serum with this ingredient for 56 days (15% ascorbid acid, 5 ppm palmitoyl tripeptide‐38). The results found improvement in skin roughness and skin tone.
This peptide is also part of the famous Matrixyl synthe’6, a blend of ingredients that also includes glycerin, water, and hydroxypropyl cyclodextrin.
Learn more about Palmitoyl Tripeptide-38Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolPullulan is a low viscosity polysaccharide (a long chain carbohydrate) with binding and film forming properties when dissolved in water. It is used to create a "silicone-like" or silky feel in cosmetics without adding viscosity.
According to a manufacturer, this ingredient's ability to easily dissolves makes it a great carrier for active ingredients.
Due to it being edible and tasteless, you'll likely find this ingredient in breath freshener strips. This ingredient is produced from the starch of the fungus, Aureobasidium pullulans.
Pullulan is stable over a broad-range of pH.
Learn more about Pullulansh-Oligopeptide-1 is a peptide found naturally in our bodies. Peptides are the building blocks for collagen and elastin in our skin.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
Studies find EGF help with:
In South Korea and China, EGF is considered a controversial ingredient. The South Korean Ministry of Food and Drug Safety has cracked down on companies with products including EGF due to false advertisement claims.
According to Dr. Zoe Draelos, growth factors have some drawbacks:
There is also controversy surrounding growth factors. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Learn more about Sh-Oligopeptide-1This peptide has similar properties to Sh-Oligopeptide-1.
In cosmetics, this ingredient is bioengineered to be identical to a human gene that codes for epidermal growth factor (EGF). EGF are signal molecules that simulate cell growth and healing.
There is also controversy surrounding EGF. The controversy is due to their mitogenic activity, or their ability to increase the number of cells. It is best to avoid using growth factors if you have psoriasis or are at risk of skin cancer. However, it should be noted EGF are not mutagenic - meaning they will not cause cancer.
Learn more about Sh-Oligopeptide-2Sh-Polypeptide-1 is a signal peptide that tells our cells to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.
It is important to note this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
Sh-Polypeptide-11 is a signal protein that tells our skin to create more fibroblast cells. Fibroblasts maintain skin structure and plays a role in wound healing.
It is important to note this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
Sh-Polypeptide-9 is a signal peptide that tells our body to create more blood vessels.
It is important to note, this ingredient is mitogenic and not mutagenic. Meaning it will stimulate cell multiplication, and will not cause cancer.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterIngredient Ratings
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Theramid Derma-Peptides 35% 46 ingredients
Numbuzin No.9 NAD+ PDRN Glow Boosting Toner 125 ingredients
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