Estée Lauder Perfectionist Pro Rapid Firm + Lift Treatment with Acetyl Hexapeptide-8 Versus Shiseido Ultimune Power Infusing Serum Concentrate
This anti-aging serum is formulated around Acetyl Glucosamine and Acetyl Hexapeptide-8 to soften the look of wrinkles.
This barrier-repair serum is formulated around Trehalose to strengthen the skin barrier and soften the look of wrinkles.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningDimethicone
EmollientButylene Glycol
HumectantCaprylic/Capric Triglyceride
MaskingGlycerin
HumectantBis-PEG-18 Methyl Ether Dimethyl Silane
EmollientPolysorbate 20
EmulsifyingLauryl PEG-9 Polydimethylsiloxyethyl Dimethicone
Skin ConditioningPolysilicone-11
Mangifera Indica Seed Butter
Skin ConditioningPhoenix Dactylifera Fruit Extract
EmollientPisum Sativum Extract
Skin ConditioningCucumis Sativus Fruit Extract
EmollientCrithmum Maritimum Extract
Skin ConditioningLaminaria Ochroleuca Extract
Skin ConditioningCommiphora Mukul Resin Extract
Skin ConditioningTriticum Vulgare Germ Extract
Skin ConditioningBambusa Vulgaris Extract
Skin ConditioningChlorella Vulgaris Extract
Skin ConditioningLaminaria Saccharina Extract
Skin ProtectingBrassica Campestris Sterols
EmollientHelianthus Annuus Seed Extract
Skin ConditioningAlgae Extract
EmollientHypnea Musciformis Extract
Skin ProtectingSigesbeckia Orientalis Extract
Skin ConditioningNymphaea Alba Flower Extract
Skin ConditioningAcetyl Glucosamine
Skin ConditioningCaffeine
Skin ConditioningGelidiella Acerosa Extract
Skin ProtectingCoffea Arabica Seed Extract
MaskingSodium Hyaluronate
HumectantLactic Acid
BufferingPropylene Glycol Dicaprate
EmollientSaccharide Isomerate
HumectantMethyl Gluceth-20
HumectantEthylhexylglycerin
Skin ConditioningAcrylamide/Sodium Acryloyldimethyltaurate Copolymer
Emulsion StabilisingHelianthus Annuus Seedcake
AbrasiveCaprylyl Glycol
EmollientIsohexadecane
EmollientTocopheryl Acetate
AntioxidantAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingGlyceryl Polymethacrylate
Sodium Polyacrylate Starch
AbsorbentSqualane
EmollientSodium PCA
HumectantUrea
BufferingZea Mays Kernel Extract
Whey Protein
Skin ConditioningPalmaria Palmata Extract
Skin ProtectingPolysorbate 80
EmulsifyingAcetyl Hexapeptide-8
HumectantTriolein
Skin ConditioningHydrolyzed Rice Extract
Skin ConditioningLinoleic Acid
CleansingTrehalose
HumectantGlycine Soja Protein
EmulsifyingGlucosamine Hcl
Phospholipids
Skin ConditioningLaminaria Digitata Extract
Skin ProtectingHordeum Vulgare Extract
EmollientPolyquaternium-51
Skin ConditioningPalmitoyl Hexapeptide-12
Skin ConditioningErgothioneine
AntioxidantAminopropyl Ascorbyl Phosphate
AntioxidantPEG-8
HumectantPhytosteryl Canola Glycerides
Skin ConditioningPentylene Glycol
Skin ConditioningOleic Acid
EmollientPalmitic Acid
EmollientXanthan Gum
EmulsifyingParfum
MaskingSodium Hydroxide
BufferingCitric Acid
BufferingSilica
AbrasiveCalcium Chloride
AstringentStearic Acid
CleansingDipropylene Glycol
HumectantSodium Palmitoyl Proline
Skin ConditioningDisodium EDTA
ChelatingBHT
AntioxidantPotassium Sorbate
PreservativePhenoxyethanol
PreservativeMica
Cosmetic ColorantCI 77891
Cosmetic ColorantCI 77491
Cosmetic ColorantCI 77492
Cosmetic ColorantCI 77499
Cosmetic ColorantWater, Dimethicone, Butylene Glycol, Caprylic/Capric Triglyceride, Glycerin, Bis-PEG-18 Methyl Ether Dimethyl Silane, Polysorbate 20, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Polysilicone-11, Mangifera Indica Seed Butter, Phoenix Dactylifera Fruit Extract, Pisum Sativum Extract, Cucumis Sativus Fruit Extract, Crithmum Maritimum Extract, Laminaria Ochroleuca Extract, Commiphora Mukul Resin Extract, Triticum Vulgare Germ Extract, Bambusa Vulgaris Extract, Chlorella Vulgaris Extract, Laminaria Saccharina Extract, Brassica Campestris Sterols, Helianthus Annuus Seed Extract, Algae Extract, Hypnea Musciformis Extract, Sigesbeckia Orientalis Extract, Nymphaea Alba Flower Extract, Acetyl Glucosamine, Caffeine, Gelidiella Acerosa Extract, Coffea Arabica Seed Extract, Sodium Hyaluronate, Lactic Acid, Propylene Glycol Dicaprate, Saccharide Isomerate, Methyl Gluceth-20, Ethylhexylglycerin, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Helianthus Annuus Seedcake, Caprylyl Glycol, Isohexadecane, Tocopheryl Acetate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Glyceryl Polymethacrylate, Sodium Polyacrylate Starch, Squalane, Sodium PCA, Urea, Zea Mays Kernel Extract, Whey Protein, Palmaria Palmata Extract, Polysorbate 80, Acetyl Hexapeptide-8, Triolein, Hydrolyzed Rice Extract, Linoleic Acid, Trehalose, Glycine Soja Protein, Glucosamine Hcl, Phospholipids, Laminaria Digitata Extract, Hordeum Vulgare Extract, Polyquaternium-51, Palmitoyl Hexapeptide-12, Ergothioneine, Aminopropyl Ascorbyl Phosphate, PEG-8, Phytosteryl Canola Glycerides, Pentylene Glycol, Oleic Acid, Palmitic Acid, Xanthan Gum, Parfum, Sodium Hydroxide, Citric Acid, Silica, Calcium Chloride, Stearic Acid, Dipropylene Glycol, Sodium Palmitoyl Proline, Disodium EDTA, BHT, Potassium Sorbate, Phenoxyethanol, Mica, CI 77891, CI 77491, CI 77492, CI 77499
Water
Skin ConditioningAlcohol Denat.
AntimicrobialGlycerin
HumectantButylene Glycol
HumectantPEG/PPG-17/4 Dimethyl Ether
Skin ConditioningTriethylhexanoin
MaskingCyclohexasiloxane
EmollientDimethicone
EmollientPhenoxyethanol
PreservativeTrehalose
HumectantAmmonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer
Emulsion StabilisingPEG-14m
Emulsion StabilisingAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingTocopheryl Acetate
AntioxidantPEG/PPG-14/7 Dimethyl Ether
Skin ConditioningRosa Damascena Flower Water
MaskingParfum
MaskingDisodium EDTA
ChelatingPotassium Hydroxide
BufferingSilica
AbrasiveIsoceteth-10
EmulsifyingLinalool
PerfumingLauryl Betaine
CleansingGinkgo Biloba Leaf Extract
Skin ConditioningGeraniol
PerfumingCitronellol
PerfumingOriganum Majorana Leaf Extract
AntiseborrhoeicNelumbo Nucifera Germ Extract
Skin ConditioningAlcohol
AntimicrobialSodium Carboxymethyl Beta-Glucan
CleansingBHT
AntioxidantThymus Serpyllum Extract
Skin ConditioningPerilla Ocymoides Leaf Extract
TonicSodium Bicarbonate
AbrasiveIris Florentina Root Extract
MaskingSodium Benzoate
MaskingGanoderma Lucidum Stem Extract
Skin ConditioningWater, Alcohol Denat., Glycerin, Butylene Glycol, PEG/PPG-17/4 Dimethyl Ether, Triethylhexanoin, Cyclohexasiloxane, Dimethicone, Phenoxyethanol, Trehalose, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, PEG-14m, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tocopheryl Acetate, PEG/PPG-14/7 Dimethyl Ether, Rosa Damascena Flower Water, Parfum, Disodium EDTA, Potassium Hydroxide, Silica, Isoceteth-10, Linalool, Lauryl Betaine, Ginkgo Biloba Leaf Extract, Geraniol, Citronellol, Origanum Majorana Leaf Extract, Nelumbo Nucifera Germ Extract, Alcohol, Sodium Carboxymethyl Beta-Glucan, BHT, Thymus Serpyllum Extract, Perilla Ocymoides Leaf Extract, Sodium Bicarbonate, Iris Florentina Root Extract, Sodium Benzoate, Ganoderma Lucidum Stem Extract
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
Learn more about Acrylates/C10-30 Alkyl Acrylate CrosspolymerBHT is a synthetic antioxidant and preservative.
As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.
As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.
The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.
However, it was recently restricted for use in the UK as of April 2024.
Learn more about BHTButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumPhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolSilica, also known as silicon dioxide, is a naturally occurring mineral. It is used as a fine, spherical, and porous powder in cosmetics.
Though it has exfoliant properties, the function of silica varies depending on the product.
The unique structure of silica enhances the spreadability and adds smoothness, making it a great texture enhancer.
It is also used as an active carrier, emulsifier, and mattifier due to its ability to absorb excess oil.
In some products, tiny microneedles called spicules are made from silica or hydrolyzed sponge. When you rub them in, they lightly polish away dead skin layers and enhance the penetration of active ingredients.
Learn more about SilicaTocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Learn more about Tocopheryl AcetateTrehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.
As a humectant, trehalose helps draw moisture from the air to your skin. This helps keep your skin hydrated.
Due to its antioxidant properties, trehalose may help with signs of aging. Antioxidants help fight free-radical molecules, unstable molecules that may damage your skin.
In medicine, trehalose and hyaluronic acid are used to help treat dry eyes.
Some animals, plants, and bacteria create trehalose as a source of energy to survive freeze or lack of water.
Learn more about TrehaloseWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water