Versus

DRMTLGY Peptide Night Cream Versus MDSolarSciences Advanced Hydration Crème

Night Moisturizer
Night Moisturizer
American Brand United States
American Brand United States

Updated on December 23, 2024

Overview

What they are

These products are both cruelty-free and reef safe night moisturizers. They have a total of 14 ingredients in common

Cool Features

They both contain ceramides and peptides

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin and scar healing

Free From

They both do not contain any harsh alcohols, parabens or sulfates

What's Inside

They both contain fragrances and silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside

What's inside

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Peptide Night Cream
Advanced Hydration Crème

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Sorbitol

Humectant
0 / 0 Helps hydrate Dry Skin Icon

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Cetyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Vitis Vinifera Seed Oil

Emollient
2-3 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

C12-15 Alkyl Benzoate

Antimicrobial

Diisostearyl Dimer Dilinoleate

Emollient

Isopropyl Myristate

Emollient
3-5 / 3 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Dimethicone

Emollient
1 / 0 Silicon Icon

Sucrose Polystearate

Emollient

Glyceryl Dilaurate

Emollient
Not safe for Fungal Acne Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Ceramide EOP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Palmitoyl Tetrapeptide-7

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Palmitoyl Tripeptide-1

Skin Conditioning
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Ferric Hexapeptide-35

Skin Conditioning
Peptide Icon

Ganoderma Lucidum Extract

Skin Protecting

Tetrahexyldecyl Ascorbate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Tremella Fuciformis Extract

Humectant
Helps hydrate Dry Skin Icon

Chamomilla Recutita Flower Extract

Masking
Helps reduce Skin Redness IconHelps reduce irritation Icon

Laminaria Digitata Extract

Skin Protecting
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Carthamus Tinctorius Seed Oil

Masking
0-2 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Lavandula Angustifolia Extract

Skin Conditioning
May cause irritation IconEU Allergen Icon

Jasminum Officinale Flower Extract

Masking
Fragrance IconMay cause irritation IconEU Allergen Icon

Cananga Odorata Flower Oil

Masking
Fragrance IconOil IconMay cause irritation IconEU Allergen IconMay worsen Eczema Icon

Santalum Album Oil

Masking
Oil IconMay cause irritation IconEU Allergen Icon

Rosa Damascena Flower Oil

Masking
Oil Icon

Salvia Triloba Leaf Extract

Antimicrobial

Citrus Aurantium Dulcis Flower Oil

Astringent
Oil Icon

Lavandula Hybrida Oil

Emollient
Oil Icon

Rosmarinus Officinalis Leaf Extract

Antimicrobial

Salvia Officinalis Oil

Masking
Oil Icon

Vanilla Planifolia Fruit Extract

Skin Conditioning
Helps reduce irritation Icon

Sodium Stearoyl Glutamate

Cleansing

PPG-12/Smdi Copolymer

Emollient

Theobroma Grandiflorum Seed Butter

Skin Conditioning
Not safe for Fungal Acne Icon

Caprylyl Glycol

Emollient
Fatty Alcohol Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Sorbitan Laurate

Emulsifying
1-2 / 1-2 Not safe for Fungal Acne Icon

Cetyl Esters

Emollient
1 / 1 Fatty Alcohol IconNot safe for Fungal Acne Icon

Hydrogenated Polyisobutene

Emollient
1 / 2

Hydroxystearic Acid

Cleansing
Not safe for Fungal Acne Icon

C18-36 Acid Glycol Ester

Emollient

C18-36 Acid Triglyceride

Emollient

Carbomer

Emulsion Stabilising
1 / 0

Xanthan Gum

Emulsifying

Pvp

Emulsion Stabilising
0 / 0

Disodium EDTA

Sodium Benzoate

Masking
Preservative Icon

Sodium Hydroxide

Buffering

Potassium Sorbate

Preservative
Preservative Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Antimicrobial, Emollient, Skin Conditioning

C12-15 Alkyl Benzoate is made up of Benzoic Acid and long chain alcohols. It has a low molecular weight.

C12-15 Alkyl Benzoate is an emollient and texture enhancer. Due to its solubility, it is often used in sunscreens to help evenly distribute active ingredients.

As an emollient, C12-15 Alkyl Benzoate helps soften and hydrate your skin. Emollients create a film on your skin that traps moisture within.

This ingredient has been reported to cause eye irritation.

Learn more about C12-15 Alkyl Benzoate
Masking, Skin Conditioning

This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride
Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Skin Conditioning

Ceramide EOP is a type of Ceramide.

EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base.

Ceramides are intercellular lipids naturally found in our skin. They bind dead skin cells together to create a barrier. The ceramides in our skin have the ability to hold water to keep our skin hydrated.

Ceramides are an important building block for our skin barrier. A strong skin barrier helps with:

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here:

Learn more about Ceramide EOP
Emollient, Emulsifying, Emulsion Stabilising

Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.

Its main roles are:

Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.

The FDA allows products labeled "alcohol-free" to have fatty alcohols.

Learn more about Cetyl Alcohol
Emollient, Skin Conditioning, Skin Protecting

Dimethicone is a type of synthetic silicone created from natural materials such as quartz.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Learn more about Dimethicone

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emollient, Emulsifying

Glyceryl Stearate is a mix of glycerin and stearic acid.

It is used to stabilize the mixing of water and oil ingredients. By preventing these ingredients from separating, it can help elongate shelf life. It can also help thicken the product's texture.

As an emollient, it helps soften skin and supports barrier-replenishing ingredients.

In cosmetics, Glyceryl Stearate is often made from vegetable oils or synthetically produced.

This ingredient may not be fungal-acne safe

Fun fact: The human body also creates Glyceryl Stearate naturally.

Learn more about Glyceryl Stearate
Skin Conditioning

Palmitoyl Tetrapeptide-7 is a lab-made peptide with anti-inflammatory and skin-repairing benefits. It's made up of four amino acids (glycine, glutamine, proline, and arginine) and palmitic acid (which helps it penetrate skin more effectively).

This ingredient helps reduce inflammation by limiting the production of interleukin-6 (IL-6), a chemical that triggers inflammatory responses, particularly after UV exposure.

Less inflammation = slower collagen breakdown and a longer-lasting, youthful appearance.

Palmitoyl Tetrapeptide-7 also stimulates collagen production and supports a healthier skin barrier.

Over time, this can improve skin firmness, hydration, and reduce the appearance of fine lines. It’s commonly paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.

This ingredient has been shown to be effective and safe in cosmetic use and you'll typically find it in small amounts (less than 0.01%).

Due to its palmitic acid base, it may not be safe for Malassezia folliculitis.

Read more about other common types of peptides here:

Learn more about Palmitoyl Tetrapeptide-7
Skin Conditioning

Palmitoyl Tripeptide-1 is also known as pal-GHK. It is made up of 3 amino acids and palmitic acid, a fatty acid that helps it absorb into skin more easily.

This peptide is as a signal peptide, meaning it tells the skin to produce more collagen. Collagen is the key protein that helps form the skin's structure and keep it plump, firm, and hydrated.

By boosting collagen production, this ingredient supports a stronger skin barrier and helps reduce the appearance of wrinkles.

You'll most likely see this ingredient paired with Palmitoyl Tetrapeptide-7 in the well-known Matrixyl 3000 complex. While results from in-house testing should be viewed cautiously, this peptide duo is among the most studied and widely used in modern skincare.

Due to its palmitic acid base, this ingredient may not be safe for Malassezia folliculitis.

Read more about other common types of peptides here:

Learn more about Palmitoyl Tripeptide-1
Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Learn more about Sodium Hydroxide
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum

When to use

77 Routines
17% use in am
83% use in pm
96% use every day
When to use See routines that use it ->
1 Routine
0% use in am
100% use in pm
100% use every day