Biretix Soothing Gel Versus Medik8 Crystal Retinal
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
HumectantSodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingPolysorbate 80
EmulsifyingHydrogenated Lecithin
EmulsifyingDimethyl Isosorbide
SolventIsohexadecane
EmollientTocopherol
AntioxidantBisabolol
AntioxidantTrehalose
HumectantBetaine
HumectantSodium PCA
HumectantUrea
BufferingPalmitoyl Hydroxypropyltrimonium Amylopectin/Glycerin Crosspolymer
Skin ConditioningHydroxypinacolone Retinoate
Skin ConditioningAloe Barbadensis Extract
Skin ConditioningButylene Glycol
HumectantLecithin
EmollientPapain
Skin ConditioningRetinol
Skin ConditioningDehydroacetic Acid
PreservativeGlucose
HumectantGlycine Soja Oil
EmollientSorbitol
HumectantPolysorbate 20
EmulsifyingFructose
HumectantAscorbyl Palmitate
AntioxidantMaltodextrin
AbsorbentGlycine
BufferingCitric Acid
BufferingPhenoxyethanol
PreservativeLactic Acid
BufferingSodium Hydroxide
BufferingPotassium Hydroxide
BufferingHydrolyzed Wheat Protein
Skin ConditioningBenzyl Alcohol
PerfumingSodium Glutamate
MaskingBeta-Sitosterol
Emulsion StabilisingSqualane
EmollientMalic Acid
BufferingGlycolic Acid
BufferingTartaric Acid
BufferingLysine
Skin ConditioningMethylparaben
PreservativeEthylparaben
PreservativeButylparaben
MaskingWater, Glycerin, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polysorbate 80, Hydrogenated Lecithin, Dimethyl Isosorbide, Isohexadecane, Tocopherol, Bisabolol, Trehalose, Betaine, Sodium PCA, Urea, Palmitoyl Hydroxypropyltrimonium Amylopectin/Glycerin Crosspolymer, Hydroxypinacolone Retinoate, Aloe Barbadensis Extract, Butylene Glycol, Lecithin, Papain, Retinol, Dehydroacetic Acid, Glucose, Glycine Soja Oil, Sorbitol, Polysorbate 20, Fructose, Ascorbyl Palmitate, Maltodextrin, Glycine, Citric Acid, Phenoxyethanol, Lactic Acid, Sodium Hydroxide, Potassium Hydroxide, Hydrolyzed Wheat Protein, Benzyl Alcohol, Sodium Glutamate, Beta-Sitosterol, Squalane, Malic Acid, Glycolic Acid, Tartaric Acid, Lysine, Methylparaben, Ethylparaben, Butylparaben
Water
Skin ConditioningCaprylic/Capric Triglyceride
MaskingGlycerin
HumectantIsododecane
EmollientCetearyl Olivate
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingCetearyl Alcohol
EmollientPPG-12/Smdi Copolymer
EmollientSorbitan Olivate
EmulsifyingTocopheryl Acetate
AntioxidantSqualane
EmollientHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingHydroxyacetophenone
AntioxidantCyclodextrin
Absorbent3-O-Ethyl Ascorbic Acid
Skin ConditioningSodium Polyaspartate
HumectantHydroxypropyl Methylcellulose
Emulsion StabilisingSodium Hyaluronate
HumectantPhenoxyethanol
PreservativeTetrahexyldecyl Ascorbate
AntioxidantDaucus Carota Sativa Seed Oil
EmollientRetinal
Skin ConditioningAlumina
AbrasiveIsostearic Acid
CleansingLecithin
EmollientPolyglyceryl-3 Polyricinoleate
EmulsifyingPolyhydroxystearic Acid
EmulsifyingLonicera Japonica Flower Extract
Skin ConditioningLonicera Caprifolium Flower Extract
PerfumingStearic Acid
CleansingCitric Acid
BufferingBHT
AntioxidantRubus Chamaemorus Seed Oil
Skin ConditioningPolysorbate 60
EmulsifyingDisodium EDTA
Ethylhexylglycerin
Skin ConditioningSorbitan Isostearate
EmulsifyingPentylene Glycol
Skin ConditioningVanilla Planifolia Fruit Extract
Skin ConditioningDipteryx Odorata Bean Extract
MaskingCoumarin
PerfumingCI 14700
Cosmetic ColorantCI 77891
Cosmetic ColorantWater, Caprylic/Capric Triglyceride, Glycerin, Isododecane, Cetearyl Olivate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, PPG-12/Smdi Copolymer, Sorbitan Olivate, Tocopheryl Acetate, Squalane, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydroxyacetophenone, Cyclodextrin, 3-O-Ethyl Ascorbic Acid, Sodium Polyaspartate, Hydroxypropyl Methylcellulose, Sodium Hyaluronate, Phenoxyethanol, Tetrahexyldecyl Ascorbate, Daucus Carota Sativa Seed Oil, Retinal, Alumina, Isostearic Acid, Lecithin, Polyglyceryl-3 Polyricinoleate, Polyhydroxystearic Acid, Lonicera Japonica Flower Extract, Lonicera Caprifolium Flower Extract, Stearic Acid, Citric Acid, BHT, Rubus Chamaemorus Seed Oil, Polysorbate 60, Disodium EDTA, Ethylhexylglycerin, Sorbitan Isostearate, Pentylene Glycol, Vanilla Planifolia Fruit Extract, Dipteryx Odorata Bean Extract, Coumarin, CI 14700, CI 77891
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinLecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that causes fungal acne.
We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.
Learn more about LecithinPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
This long ingredient is a copolymer of sodium acrylate and sodium acryloyldimethyl taurate monomers.
It is used to help stabilize other ingredients and create a thicker gel-like texture.
Emulsifiers prevent oils and waters from separating.
Learn more about Sodium Acrylate/Sodium Acryloyldimethyl Taurate CopolymerSqualane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, itâs technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term âoil-freeâ isnât regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Learn more about SqualaneWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water