Versus

Theramid Clinical Vitamin A Versus Paula's Choice 1% Retinol Treatment - US

Serum
Facial Treatment
Spanish Brand Spain
American Brand United States

Updated on January 17, 2025

Overview

What they are

These products are both vegan, cruelty-free, and reef safe . They have a total of 9 ingredients in common

Cool Features

They both contain ceramides, exfoliants, retinoid and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, common allergens, parabens or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

About this product

About this product

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Clinical Vitamin A
1% Retinol Treatment

Water

Skin Conditioning

Dimethicone

Emollient
1 / 0 Silicon Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Isononyl Isononanoate

Emollient

Castor Isostearate Succinate

Skin Conditioning
Not safe for Fungal Acne Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

C12-15 Alkyl Benzoate

Antimicrobial

Dimethicone Crosspolymer

Emulsion Stabilising

PEG-33

Humectant

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Behenyl Alcohol

Emollient
Fatty Alcohol Icon

PEG-100 Stearate

0 / 0 Not safe for Fungal Acne Icon

Pentaerythrityl Tetraisostearate

Emollient
2 / 0 Not safe for Fungal Acne Icon

Polymethylsilsesquioxane

Silicon Icon

Tetrahexyldecyl Ascorbate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Retinol

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Ceramide Ng

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Palmitoyl Tetrapeptide-7

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Palmitoyl Hexapeptide-12

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid Icon

Dipotassium Glycyrrhizate

Humectant
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Glycyrrhiza Glabra Root Extract

Bleaching
Good for Dark Spots Icon

Avena Sativa Kernel Extract

Abrasive
Exfoliant IconAntioxidant IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Arctium Lappa Seed Oil

Emollient
Oil Icon

Salix Alba Extract

Skin Conditioning

Glycine Soja Sterols

Emollient
0 / 0 Not safe for Fungal Acne Icon

Lecithin

Emollient

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Hydrolyzed Soy Protein

Humectant

Sorbitan Laurate

Emulsifying
1-2 / 1-2 Not safe for Fungal Acne Icon

Acetyl Dipeptide-1 Cetyl Ester

Skin Conditioning
Peptide Icon

Disodium EDTA

Hydroxyethylcellulose

Emulsion Stabilising

Palmitoyl Tripeptide-1

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Sodium Hydroxide

Buffering

Tribehenin

Emollient
0 / 0 Not safe for Fungal Acne Icon

Caprylyl Glycol

Emollient

Ethylhexylglycerin

Skin Conditioning

Pentylene Glycol

Skin Conditioning

PEG-75 Shea Butter Glycerides

Emulsifying
Not safe for Fungal Acne Icon

PPG-12/Smdi Copolymer

Emollient

PEG-10 Phytosterol

Emulsifying

PEG-8 Dimethicone

Emulsifying
Silicon Icon

PEG-14

Humectant

Magnesium Aluminum Silicate

Absorbent
0 / 0

Arachidyl Glucoside

Emulsifying

Arachidyl Alcohol

Emollient

Sclerotium Gum

Emulsion Stabilising

Carbomer

Emulsion Stabilising
1 / 0

Phenoxyethanol

Preservative
Preservative Icon

Benzoic Acid

Masking
Preservative IconMay worsen Eczema Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Skin Conditioning

Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.

Why is retinol famous?

It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.

Retinol is proven to:

This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.

Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).

Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

We recommend speaking with a medical professional about using this ingredient during pregnancy.

Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.

Read about Tretinoin

Learn more about Retinol
Skin Conditioning

Ceramide NG is a type of Ceramide. The NG stands for a sphinganine base.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.

If you would like to eat ceramides, sweet potatoes contain a small amount.

Read more about other common types of ceramides here: Ceramide AP Ceramide EOP Ceramide NP

Learn more about Ceramide Ng
Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids.

These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients such as sunflower.

As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.

As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can help ingredients be better absorbed by the skin. The phospholipids in Lecithin can produce liposomes. Liposomes help other ingredients get through the skin barrier.

Due to its fatty acid content, this ingredient may not be fungal-acne safe.

Learn more about Lecithin
Emulsion Stabilising, Skin Conditioning

Sclerotium Gum is a polysaccharide gum made by the fungus, Sclerotium rolfssii. It is similar to xanthan gum.

In cosmetics, Sclerotium Gum is used to thicken the texture and to help stabilize other ingredients.

As an emulsifier, Sclerotium Gum helps prevent ingredients from separating, such as water and oil.

Learn more about Sclerotium Gum
Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

When to use

19 Routines
5% use in am
95% use in pm
37% use every day
397 Routines
8% use in am
92% use in pm
65% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Theramid Clinical Vitamin A 32 ingredients

Clinical Vitamin A hasn't been rated yet.
Rate it now

Paula's Choice 1% Retinol Treatment 53 ingredients

4.5 /5
from 4 ratings
Ninamujer's avatar

Nina

1 year ago
Review

Love it
My favorite retinol. Been using it for a year and never had any bad reactions (be sure to follow instructions like starting slow). It's a bit pricey but worth it