Versus

Shani Darden Retinol Reform Versus Medik8 Crystal Retinal 6

Serum
Serum
American Brand United States
British Brand United Kingdom

Updated on January 29, 2025

Overview

What they are

These products are both cruelty-free serums. They have a total of 11 ingredients in common

Cool Features

They both contain retinoid and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, parabens, silicones or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

Shani Darden Retinol Reform 44 ingredients

Medik8 Crystal Retinal 6 47 ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Shani Darden Retinol Reform 44 ingredients

Medik8 Crystal Retinal 6 47 ingredients

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Retinol Reform
Crystal Retinal 6

Water

Skin Conditioning

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Isododecane

Emollient

Cetearyl Olivate

Not safe for Fungal Acne Icon

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Emulsion Stabilising

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

PPG-12/Smdi Copolymer

Emollient

Sorbitan Olivate

Emulsifying
Not safe for Fungal Acne Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Titanium Dioxide

Cosmetic Colorant
0 / 0 Mineral UV Filter IconNon-Reef-Safe Icon

Eclipta Prostrata Extract

Skin Conditioning

Cyclodextrin

Absorbent

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Emulsion Stabilising

Phenoxyethanol

Preservative
Preservative Icon

Melia Azadirachta Leaf Extract

Skin Conditioning

Hydroxypropyl Methylcellulose

Emulsion Stabilising

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Tetrahexyldecyl Ascorbate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Rubus Chamaemorus Seed Oil

Skin Conditioning
Oil IconNot safe for Fungal Acne Icon

Alumina

Abrasive
Exfoliant Icon

Isostearic Acid

Cleansing
Bad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Lecithin

Emollient
Helps hydrate Dry Skin Icon

Polyglyceryl-3 Polyricinoleate

Emulsifying
Not safe for Fungal Acne Icon

Polyhydroxystearic Acid

Emulsifying
Not safe for Fungal Acne Icon

Stearic Acid

Cleansing
2-3 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Pentylene Glycol

Skin Conditioning

Retinal

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Moringa Oleifera Seed Oil

Emollient
Oil IconHelps hydrate Dry Skin IconHelps reduce irritation IconNot safe for Fungal Acne Icon

Sodium Polyaspartate

Humectant

Climbazole

Antimicrobial
Preservative Icon

Disodium EDTA

Lonicera Japonica Flower Extract

Skin Conditioning

Lonicera Caprifolium Flower Extract

Perfuming
Fragrance Icon

Daucus Carota Sativa Seed Oil

Emollient
Oil IconHelps hydrate Dry Skin IconHelps reduce irritation Icon

Ethylhexylglycerin

Skin Conditioning

3-O-Ethyl Ascorbic Acid

Skin Conditioning
Vitamin C IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores Icon

Dipteryx Odorata Bean Extract

Masking
Fragrance Icon

Hydroxyacetophenone

Antioxidant
Antioxidant IconHelps reduce irritation Icon

Polysorbate 60

Emulsifying
Not safe for Fungal Acne Icon

Sorbitan Isostearate

Emulsifying
1-2 / 0 Not safe for Fungal Acne Icon

Vanilla Planifolia Fruit Extract

Skin Conditioning
Helps reduce irritation Icon

Decylene Glycol

Skin Conditioning

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

BHT

Antioxidant
Antioxidant Icon

Coumarin

Perfuming
Fragrance IconMay cause irritation IconEU Allergen Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Masking, Skin Conditioning

This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin

This is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.

It is also an emulsifer, meaning it prevents ingredients such as oil and water from separating. It also helps evenly disperse other ingredients.

Antioxidant, Skin Conditioning

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Emulsifying

Sorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.

As an emulsifier, Sorbitan Isostearate prevents oils and water from separating.

Due to its isostearic acid base, it may not be safe for Malassezia or fungal acne.

Learn more about Sorbitan Isostearate
Emulsifying

Polysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.

Polysorbate 60 is sorbitol-based and created from the ethoxylation of sorbitan. Ethoxylation is a chemical reaction used to add ethylene oxide. Sorbitan is a the dehydrated version of sorbitol, a sugar found in fruits.

In this case, the 60 comes from reacting 60 units of ethylene oxide with sorbitan.

Polysorbates are commonly used in medicine and foods.

Learn more about Polysorbate 60
Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.

This ingredient has emollient and emulsifying properties.

As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.

As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.

This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.

Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.

We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.

Learn more about Lecithin
BHT
Antioxidant, Masking

BHT is a synthetic antioxidant and preservative.

As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.

As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.

The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.

However, it was recently restricted for use in the UK as of April 2024.

Learn more about BHT
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.

When to use

Shani Darden Retinol Reform 44 ingredients

Medik8 Crystal Retinal 6 47 ingredients

59 Routines
0% use in am
100% use in pm
53% use every day
When to use See routines that use it ->
105 Routines
1% use in am
99% use in pm
65% use every day
When to use See routines that use it ->

Reviews

Here's what our community thinks

Shani Darden Retinol Reform 44 ingredients

4.0 /5
from 1 rating
Absorbs Well (1) Expensive (1) Light (1)
anemone's avatar

anemone

1 year ago
Review

the ingredients are fantastic. if you’re willing to splurge on a quality retinol serum, this one would be a great choice.
however, the smell is horrible. if you can get past the smell, though, this would probably be a great option for sensitive skin as it doesn’t have any added fragrance.

#expensive
#light
#absorbs well
#strong scent

Medik8 Crystal Retinal 6 47 ingredients

3.5 /5
from 2 ratings
Expensive (2) Absorbs Well (1) Broke Me Out (1)
verenski's avatar

verenski

8 months ago
Review

Great retinal serum but not for dry skin. Could be a little bit irritating too! The price is also mindblowing! Too expensive! It has a nice vanilla like scent

#expensive
#absorbs well
#light scent
rehaylew's avatar

Rebecca

9 months ago
Review

Just about safe enough for me to use on my forehead and the tops of my cheeks, but any further down my face/neck it causes massive breakouts and fungal acne which takes months to get rid of. For the price, it's just not worth it.

#expensive
#broke me out