Medik8 Crystal Retinal 6 Versus Avène RetrinAL 0.05% Cream
Updated on January 29, 2025
Overview
Cool Features
They both contain retinoid
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, parabens, silicones or sulfates
What's Inside
They both contain oils
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Medik8 Crystal Retinal 6 47 ingredients
Avène RetrinAL 0.05% Cream 19 ingredients
About this product
About this product
At a glance
Click on any of the items below to learn more
Medik8 Crystal Retinal 6 47 ingredients
Avène RetrinAL 0.05% Cream 19 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningCaprylic/Capric Triglyceride
MaskingGlycerin
Humectant
Isododecane
EmollientCetearyl Olivate
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingCetearyl Alcohol
Emollient
PPG-12/Smdi Copolymer
EmollientSorbitan Olivate
Emulsifying
Tocopheryl Acetate
Antioxidant
Titanium Dioxide
Cosmetic Colorant
Eclipta Prostrata Extract
Skin ConditioningCyclodextrin
AbsorbentSqualane
Emollient
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingPhenoxyethanol
Preservative
Melia Azadirachta Leaf Extract
Skin ConditioningHydroxypropyl Methylcellulose
Emulsion StabilisingSodium Hyaluronate
Humectant
Tetrahexyldecyl Ascorbate
Antioxidant
Rubus Chamaemorus Seed Oil
Skin Conditioning
Alumina
Abrasive
Isostearic Acid
Cleansing
Lecithin
EmollientPolyglyceryl-3 Polyricinoleate
Emulsifying
Polyhydroxystearic Acid
Emulsifying
Stearic Acid
Cleansing
Pentylene Glycol
Skin ConditioningRetinal
Skin Conditioning
Moringa Oleifera Seed Oil
Emollient
Sodium Polyaspartate
HumectantClimbazole
Antimicrobial
Disodium EDTA
Lonicera Japonica Flower Extract
Skin ConditioningLonicera Caprifolium Flower Extract
Perfuming
Daucus Carota Sativa Seed Oil
Emollient
Ethylhexylglycerin
Skin Conditioning3-O-Ethyl Ascorbic Acid
Skin Conditioning
Dipteryx Odorata Bean Extract
Masking
Hydroxyacetophenone
Antioxidant
Polysorbate 60
Emulsifying
Sorbitan Isostearate
Emulsifying
Vanilla Planifolia Fruit Extract
Skin ConditioningDecylene Glycol
Skin Conditioning1,2-Hexanediol
Skin ConditioningBHT
Antioxidant
Coumarin
Perfuming
Water, Caprylic/Capric Triglyceride, Glycerin, Isododecane, Cetearyl Olivate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, PPG-12/Smdi Copolymer, Sorbitan Olivate, Tocopheryl Acetate, Titanium Dioxide, Eclipta Prostrata Extract, Cyclodextrin, Squalane, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Phenoxyethanol, Melia Azadirachta Leaf Extract, Hydroxypropyl Methylcellulose, Sodium Hyaluronate, Tetrahexyldecyl Ascorbate, Rubus Chamaemorus Seed Oil, Alumina, Isostearic Acid, Lecithin, Polyglyceryl-3 Polyricinoleate, Polyhydroxystearic Acid, Stearic Acid, Pentylene Glycol, Retinal, Moringa Oleifera Seed Oil, Sodium Polyaspartate, Climbazole, Disodium EDTA, Lonicera Japonica Flower Extract, Lonicera Caprifolium Flower Extract, Daucus Carota Sativa Seed Oil, Ethylhexylglycerin, 3-O-Ethyl Ascorbic Acid, Dipteryx Odorata Bean Extract, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Vanilla Planifolia Fruit Extract, Decylene Glycol, 1,2-Hexanediol, BHT, Coumarin
Water
Skin ConditioningCaprylic/Capric Triglyceride
MaskingParaffinum Liquidum
Emollient
Glyceryl Stearate
Emollient
PEG-100 Stearate
Squalane
Emollient
Propylene Glycol
Humectant
Microcrystalline Wax
Emulsion Stabilising
PEG-40 Hydrogenated Castor Oil
Emulsifying
BHT
Antioxidant
Caprylyl Glycol
EmollientCarbomer
Emulsion StabilisingDisodium EDTA
Oleoyl Dipeptide-15
Skin Conditioning
Oleoyl Tetrapeptide-31
Antioxidant
CI 17200
Cosmetic ColorantRetinal
Skin Conditioning
Tocopheryl Glucoside
EmollientTriethanolamine
BufferingWater, Caprylic/Capric Triglyceride, Paraffinum Liquidum, Glyceryl Stearate, PEG-100 Stearate, Squalane, Propylene Glycol, Microcrystalline Wax, PEG-40 Hydrogenated Castor Oil, BHT, Caprylyl Glycol, Carbomer, Disodium EDTA, Oleoyl Dipeptide-15, Oleoyl Tetrapeptide-31, CI 17200, Retinal, Tocopheryl Glucoside, Triethanolamine
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterThis ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.
Learn more about Caprylic/Capric TriglycerideSqualane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.
Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.
Research shows that squalane is non-irritating (even at 100% concentration).
In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.
The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.
Is squalane vegan?
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Learn more about SqualaneRetinal is a form of retinoid. Retinoids are the gold-standard class of anti-aging ingredients.
Retinal has many benefits as other retinoids: improve skin texture, reduce large pores, reduce the effects of aging, reduce the visibility of dark spots, heal scars, and fight acne.
Studies show retinal may work at a faster rate than retinol due to its structure.
All retinoids have to be converted into retinoic acid before starting to work. Some retinoids take several steps of conversion before binding. Retinal is only one step away, making it more potent.
Like other retinoids, retinal may be irritating. It is best to ease into using this ingredient frequently.
Using the 'ramp up' method, start by using retinol once a week. This gives your skin time to adjust and decrease irritation. Once you feel ready, you can slowly increase the frequency of retinol use.
Using retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
Learn more about RetinalDisodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTABHT is a synthetic antioxidant and preservative.
As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.
As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.
The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.
However, it was recently restricted for use in the UK as of April 2024.
Learn more about BHTIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Medik8 Crystal Retinal 6 47 ingredients
Avène RetrinAL 0.05% Cream 19 ingredients
Reviews
Here's what our community thinks
Medik8 Crystal Retinal 6 47 ingredients
Just about safe enough for me to use on my forehead and the tops of my cheeks, but any further down my face/neck it causes massive breakouts and fungal acne which takes months to get rid of. For the price, it's just not worth it.
Great retinal serum but not for dry skin. Could be a little bit irritating too! The price is also mindblowing! Too expensive! It has a nice vanilla like scent
