Versus

ISDIN Melaclear Advanced Versus Clinique Even Better Clinical Brightening Moisturizer

Serum
General Moisturizer
Spanish Brand Spain
American Brand United States

Updated on June 28, 2024

Overview

What they are

These products are both reef safe . They have a total of 11 ingredients in common

Cool Features

They both contain BHA and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any common allergens, oils, parabens or sulfates

What's Inside

They both contain silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Even Better Clinical Brightening Moisturizer

Water

Skin Conditioning

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Octyldodecyl Myristate

Emollient

Dimethicone

Emollient
1 / 0 Silicon Icon

Di-C12-15 Alkyl Fumarate

Emollient

Isopropyl Isostearate

Emollient
4-5 / 0 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Diisostearyl Malate

Emollient

PEG-100 Stearate

0 / 0 Not safe for Fungal Acne Icon

PEG-8

Humectant

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Ascorbyl Glucoside

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Butyrospermum Parkii Butter

Skin Conditioning
Helps hydrate Dry Skin IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Tribehenin

Emollient
0 / 0 Not safe for Fungal Acne Icon

Cetyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Acetyl Glucosamine

Skin Conditioning

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Dipotassium Glycyrrhizate

Humectant
Helps reduce Skin Redness IconHelps reduce irritation IconGood for Dark Spots Icon

Sucrose

Humectant
Helps hydrate Dry Skin Icon

Caffeine

Skin Conditioning
Helps reduce irritation IconHelps with Anti-Aging Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Cucumis Sativus Fruit Extract

Emollient
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation Icon

Camellia Sinensis Leaf Extract

Antimicrobial
Antioxidant IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging Icon

Saccharomyces Lysate Extract

Humectant
Helps hydrate Dry Skin Icon

Algae Extract

Emollient
May worsen Oily Skin Icon

Helianthus Annuus Seed Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

Hordeum Vulgare Extract

Emollient

Yeast Extract

Skin Conditioning
Not safe for Fungal Acne Icon

Saccharum Officinarum Extract

Moisturising

Salicylic Acid

Masking
BHA IconPreservative IconGood for Oily Skin IconGood for Minimizing Pores IconHelps fight Acne IconHelps brighten skin IconCan worsen Dry Skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

Propylene Glycol Dicaprate

Emollient

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Behenyl Alcohol

Emollient
Fatty Alcohol Icon

Cetearyl Glucoside

Emulsifying

Xanthan Gum

Emulsifying

Potassium Hydroxide

Buffering

Sodium Hydroxide

Buffering

Disodium Phosphate

Buffering

Sodium Phosphate

Buffering

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Dimethoxytolyl Propylresorcinol

Antioxidant
Antioxidant Icon

Sorbitan Oleate

Emulsifying
3 / 0 Bad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Polysilicone-11

Di-C12-18 Alkyl Dimonium Chloride

Skin Conditioning

Hexylene Glycol

Emulsifying
0-2 / 0-1

Polysorbate 80

Emulsifying
0 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Caprylyl Glycol

Emollient

Acrylamide/Sodium Acryloyldimethyltaurate Copolymer

Emulsion Stabilising

Isohexadecane

Emollient

Disodium EDTA

BHT

Antioxidant
Antioxidant Icon

Chlorphenesin

Antimicrobial
Preservative Icon

Phenoxyethanol

Preservative
Preservative Icon

Sodium Benzoate

Masking
Preservative Icon

Potassium Sorbate

Preservative
Preservative Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Emollient, Skin Conditioning, Skin Protecting

Dimethicone is a type of synthetic silicone created from natural materials such as quartz.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Learn more about Dimethicone
Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Learn more about Sodium Hydroxide
Humectant, Skin Conditioning

Dipotassium Glycyrrhizate comes from licorice root.

Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.

One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.

Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.

Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.

Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.

Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.

Learn more about Dipotassium Glycyrrhizate
Masking, Preservative, Skin Conditioning

Salicylic Acid (also known as beta hydroxy acid or BHA) is one of the most well-known ingredients for treating skin that struggles with blackheads and acne. It helps to exfoliate both the skin's surface and pores, and also acts as an anti-inflammatory agent.

This multitasking property makes it a great ingredient for cleaning out pores, controlling oil production, and reducing inflammation.

Unlike AHAs which are water soluble, Salicylic Acid is oil soluble. This means that it's able to exfoliate the inside of pores and reduce blackheads.

Concentrations of 0.5-2% are recognized by the U.S. FDA as an over-the-counter topical acne product.

It can cause irritation and/or dryness if one's skin already has a compromised moisture barrier, so it's best to focus on repairing that before introducing a Salicylic Acid into your routine.

In general, Salicylic Acid is a great ingredient for oily acne-prone skin.

While salicylic acid does not increase sun-sensitivity, we still recommend wearing SPF.

If you are looking for the ingredient called BHA or Butylated Hydroxyanisole, click here.

Learn more about Salicylic Acid

We don't have a description for Polysilicone-11 yet.

Antioxidant, Skin Conditioning

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum
Masking, Preservative

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Learn more about Sodium Benzoate

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Learn more about Disodium EDTA
Buffering, Masking

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.

If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.

Read more about some other popular AHA's here:

Learn more about Citric Acid

When to use

4 Routines
50% use in am
50% use in pm
75% use every other_day
7 Routines
71% use in am
29% use in pm
86% use every day

Reviews

Here's what our community thinks

ISDIN Melaclear Advanced 33 ingredients

Melaclear Advanced hasn't been rated yet.
Rate it now

Clinique Even Better Clinical Brightening Moisturizer 57 ingredients

1.0 /5
from 1 rating
PeeyJeey's avatar

PeeyJeey

2 years ago
Review

Piling
I've tried it multiple times with different combinations of my skin care products, i've even tried it with nothing else on and there's always piling i'm not sure why. It also doesnt feel very moisturizing.