Versus

Clinique Smart Night Clinical MD Multi-Dimensional Repair Treatment Retinol Versus Clinique Smart Clinical MD Multi-Dimensional Age Transformer Resculpt

Facial Treatment
General Moisturizer
American Brand United States
American Brand United States

Updated on June 28, 2024

Overview

What they are

These products are both reef safe . They have a total of 16 ingredients in common

Cool Features

They both contain hyaluronic acid, peptides, Vitamin C and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any common allergens, fragrances or parabens

What's Inside

They both contain oils and silicones

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Smart Night Clinical MD Multi-Dimensional Repair Treatment Retinol

Water

Skin Conditioning

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

PPG-15 Stearyl Ether

Emollient

C12-20 Acid PEG-8 Ester

Emulsifying
Not safe for Fungal Acne Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon
Smart Clinical MD Multi-Dimensional Age Transformer Resculpt

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Caprylyl Methicone

Skin Conditioning
Silicon Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Alcohol Denat.

Antimicrobial
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon

Dimethicone

Emollient
1 / 0 Silicon Icon

Isododecane

Emollient

PEG-10 Dimethicone

Skin Conditioning
Silicon Icon

Dipropylene Glycol

Masking

Prunus Amygdalus Dulcis Seed Extract

Skin Conditioning

Cucumis Melo Fruit Extract

Skin Conditioning

Persea Gratissima Oil

Skin Conditioning
0-3 / 0 Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Saccharomyces Lysate Extract

Humectant
Helps hydrate Dry Skin Icon

Acetyl Glucosamine

Skin Conditioning

Porphyridium Cruentum Extract

Skin Conditioning

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Skin Conditioning
Peptide IconHelps with Anti-Aging Icon

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging Icon

Palmitoyl Tetrapeptide-7

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Acetyl Octapeptide-3

Humectant
Peptide IconHelps with Anti-Aging Icon

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

Decarboxy Carnosine Hcl

Skin Conditioning

Acetyl Carnitine Hcl

Skin Conditioning

Caffeine

Skin Conditioning
Helps reduce irritation IconHelps with Anti-Aging Icon

Creatine

Skin Conditioning

Sigesbeckia Orientalis Extract

Skin Conditioning

Palmitoyl Tripeptide-1

Skin Conditioning
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Polygonum Cuspidatum Root Extract

Antioxidant
Antioxidant Icon

Centella Asiatica Extract

Cleansing
Helps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon

Glycine Soja Protein

Emulsifying

Ergothioneine

Antioxidant
Antioxidant IconHelps reduce irritation IconGood for Dark Spots Icon

Propylene Glycol Dicaprylate

Emollient

PEG-150

Humectant

Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone

Skin Conditioning
Silicon Icon

Jojoba Esters

Emollient
Not safe for Fungal Acne Icon

Lactis Proteinum

Skin Conditioning

Adenosine Phosphate

Skin Conditioning

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Lactic Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin IconMay worsen Eczema IconMay worsen Rosacea Icon

Yeast Extract

Skin Conditioning
Not safe for Fungal Acne Icon

Linoleic Acid

Cleansing
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Sodium Hyaluronate

Humectant
0 / 0 Hyaluronic Acid IconHelps hydrate Dry Skin Icon

Phytantriol

Humectant
2 / 2

Glycine Soja Seed Extract

Skin Conditioning
Helps reduce irritation IconGood for Dark Spots Icon

Disteardimonium Hectorite

Stabilising

Propylene Carbonate

Solvent

Menthanediol

Skin Conditioning

Hydroxypropyl Methylcellulose

Emulsion Stabilising

Pullulan

Polyquaternium-51

Skin Conditioning
Helps hydrate Dry Skin Icon

Sodium Hydroxide

Buffering

Calcium Chloride

Astringent

Carbomer

Emulsion Stabilising
1 / 0

Sea Whip Extract

Skin Conditioning

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Caprylyl Glycol

Emollient

Tetrahexyldecyl Ascorbate

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps brighten skin Icon

Citric Acid

Buffering
AHA IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay worsen Rosacea Icon

Potassium Sulfate

Sulfate Icon

Sodium Hexametaphosphate

Masking

Sodium Citrate

Buffering

Potassium Sorbate

Preservative
Preservative Icon

Sodium Benzoate

Masking
Preservative Icon

Phenoxyethanol

Preservative
Preservative Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emollient, Skin Conditioning, Skin Protecting

Dimethicone is a type of synthetic silicone created from natural materials such as quartz.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Learn more about Dimethicone
Skin Conditioning, Tonic

We don't have a description for Sigesbeckia Orientalis Extract yet.

Humectant, Skin Conditioning

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Learn more about Sodium Hyaluronate
Skin Conditioning

Caffeine is most associated with coffee, tea, and cacao. In skincare, it helps with calming inflammation and is rich in antioxidants.

While caffeine is used to treat cellulite and and dark circles, further studies are needed to prove this. It has been believed to help with these skin conditions due to its ability to dilate blood vessels and increase blood flow.

Some studies are looking into caffeine's ability to protect against UV rays.

Learn more about Caffeine
Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Antioxidant, Skin Conditioning

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate
Cleansing, Emollient, Skin Conditioning

Linoleic Acid is also known as Vitamin F. It is a fatty acid with emollient and skin conditioning properties. Our top layer of skin, or epidermis, contains high amounts of linoleic acid naturally.

Your body uses linoleic acid to build ceramides and prostaglandins. Ceramides keep your skin's barrier hydrated and strong while prosaglandins help control inflammation and healing. Needless to say, linoleic acid is crucial for having a strong skin barrier.

One study found applying linoleic acid rich sunflower oil to be more effective at repairing the skin barrier than oleic rich olive oil.

Linoleic acid is an essential fatty acid, meaning our bodies cannot create it on its own. We need to get linoleic acid through foods such as nuts and vegetable oils.

Acne-prone skin tends to have linoleic acid and high levels of oleic acid.

Linoleic acid can also help treat acne by softening sebum to prevent clogged pores. Another study found using 2.5% linoleic acid gel for 4 weeks showed a 25% reduction in small comedones.

This ingredient can also help lighten hyperpigmentation or sun spots by disrupting the melanin production process. It also helps your skin shed melanin pigment from your skin caused by UV exposure.

Due to its role in the production of the fatty acid prostaglandin, linoleic acid can also help reduce inflammation and support wound healing.

Linoleic acid is not always fungal-acne safe; it may trigger flare-ups in sensitive individuals.

Learn more about Linoleic Acid
Humectant, Skin Conditioning

Acetyl Hexapeptide-8 is a peptide. A common name for this peptide is Argireline.

Argireline has a similar function to botox; it prevents muscle movement and contractions slightly. By preventing muscles from moving, argireline also prohibits the formation of fine lines and wrinkles. However, research is lacking in proving this ingredient to be as effective as botox.

On the other hand, argireline tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.

Read more about other common types of peptides here:

Learn more about Acetyl Hexapeptide-8
Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Learn more about Sodium Hydroxide
Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.

It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.

Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.

This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.

Learn more about Caprylyl Glycol
Emulsion Stabilising, Gel Forming

Carbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.

A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.

Skin Conditioning

Polyquaternium-51 is a polymer salt. It helps hydrate the skin by creating a film on top. This film traps moisture in, keeping your skin soft and hydrated.

Preservative

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Learn more about Potassium Sorbate
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

When to use

4 Routines
0% use in am
100% use in pm
50% use every day
1 Routine
100% use in am
0% use in pm
100% use every day