Origins Plantscription Multi-Powered Youth Serum Versus Origins Dr. Andrew Weil For Origins™ Mega-Bright Dark Spot Correcting Serum
This anti-aging serum is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles and refine skin texture.
This brightening serum is formulated around Ascorbyl Glucoside and Salicylic Acid to fade the look of dark spots and brighten dull-looking skin.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningButylene Glycol
HumectantNiacinamide
SmoothingGlycerin
HumectantHeptyl Undecylenate
EmollientOctyldodecanol
EmollientGlycereth-26
HumectantSodium Acrylates Copolymer
Algae Extract
EmollientIllicium Verum Fruit/Seed Oil
MaskingCitrus Aurantium Bergamia Fruit Oil
MaskingPelargonium Graveolens Flower Oil
MaskingLavandula Angustifolia Oil
MaskingCitrus Limon Peel Oil
MaskingLitsea Cubeba Fruit Oil
MaskingCitrus Nobilis Peel Oil
MaskingMyristica Fragrans Kernel Oil
MaskingCitrus Aurantium Dulcis Oil
MaskingRosa Damascena Flower Oil
MaskingHibiscus Abelmoschus Extract
MaskingCarthamus Tinctorius Seed Oil
MaskingLinalool
PerfumingGeraniol
PerfumingCitronellol
PerfumingLimonene
PerfumingAnogeissus Leiocarpus Bark Extract
Skin ProtectingAcetyl Hexapeptide-8
HumectantPalmitoyl Tripeptide-1
Skin ConditioningAcetyl Octapeptide-3
HumectantPalmitoyl Tetrapeptide-7
Skin ConditioningPalmitoyl Hexapeptide-12
Skin ConditioningDipeptide Diaminobutyroyl Benzylamide Diacetate
Skin ConditioningSodium Hyaluronate
HumectantSigesbeckia Orientalis Extract
Skin ConditioningCommiphora Mukul Resin Extract
Skin ConditioningLaminaria Saccharina Extract
Skin ProtectingGlucosamine Hcl
Bambusa Vulgaris Extract
Skin ConditioningCaffeine
Skin ConditioningRosmarinus Officinalis Leaf Extract
AntimicrobialMolasses Extract
Skin ConditioningTocopheryl Acetate
AntioxidantScutellaria Baicalensis Root Extract
AstringentPyrus Malus Fruit Extract
Skin ConditioningCucumis Sativus Fruit Extract
EmollientPisum Sativum Extract
Skin ConditioningCaprylic/Capric Triglyceride
MaskingLecithin
EmollientXanthan Gum
EmulsifyingCaprylyl Glycol
EmollientHexylene Glycol
EmulsifyingPEG-8
HumectantGlyceryl Polymethacrylate
Carbomer
Emulsion StabilisingPolysorbate 20
EmulsifyingSodium Metabisulfite
AntioxidantSodium Sulfite
PreservativeDisodium EDTA
ChelatingSodium Phytate
ChelatingBHT
AntioxidantPotassium Sorbate
PreservativePhenoxyethanol
PreservativeWater, Butylene Glycol, Niacinamide, Glycerin, Heptyl Undecylenate, Octyldodecanol, Glycereth-26, Sodium Acrylates Copolymer, Algae Extract, Illicium Verum Fruit/Seed Oil, Citrus Aurantium Bergamia Fruit Oil, Pelargonium Graveolens Flower Oil, Lavandula Angustifolia Oil, Citrus Limon Peel Oil, Litsea Cubeba Fruit Oil, Citrus Nobilis Peel Oil, Myristica Fragrans Kernel Oil, Citrus Aurantium Dulcis Oil, Rosa Damascena Flower Oil, Hibiscus Abelmoschus Extract, Carthamus Tinctorius Seed Oil, Linalool, Geraniol, Citronellol, Limonene, Anogeissus Leiocarpus Bark Extract, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Acetyl Octapeptide-3, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Sodium Hyaluronate, Sigesbeckia Orientalis Extract, Commiphora Mukul Resin Extract, Laminaria Saccharina Extract, Glucosamine Hcl, Bambusa Vulgaris Extract, Caffeine, Rosmarinus Officinalis Leaf Extract, Molasses Extract, Tocopheryl Acetate, Scutellaria Baicalensis Root Extract, Pyrus Malus Fruit Extract, Cucumis Sativus Fruit Extract, Pisum Sativum Extract, Caprylic/Capric Triglyceride, Lecithin, Xanthan Gum, Caprylyl Glycol, Hexylene Glycol, PEG-8, Glyceryl Polymethacrylate, Carbomer, Polysorbate 20, Sodium Metabisulfite, Sodium Sulfite, Disodium EDTA, Sodium Phytate, BHT, Potassium Sorbate, Phenoxyethanol
Water
Skin ConditioningDimethicone
EmollientIsododecane
EmollientCyclopentasiloxane
EmollientPolysilicone-11
Butylene Glycol
HumectantAscorbyl Glucoside
AntioxidantPEG-10 Dimethicone
Skin ConditioningCitrus Aurantium Dulcis Peel Oil
MaskingPelargonium Graveolens Oil
MaskingCananga Odorata Flower Oil
MaskingEugenia Caryophyllus Bud Oil
MaskingRosa Damascena Flower Oil
MaskingJasminum Officinale Oil
MaskingViola Odorata Flower/Leaf Extract
MaskingPolianthes Tuberosa Extract
MaskingCitronellol
PerfumingGeraniol
PerfumingBenzyl Benzoate
AntimicrobialEugenol
PerfumingPEG-6
HumectantRosa Roxburghii Fruit Extract
TonicPaeonia Albiflora Root Extract
Skin ConditioningGentiana Lutea Root Extract
Skin ConditioningHordeum Vulgare Extract
EmollientTriticum Vulgare Germ Extract
Skin ConditioningHydrolyzed Rice Bran Extract
Skin ConditioningAlgae Extract
EmollientSalicylic Acid
MaskingCholesterol
EmollientGlycerin
HumectantSolanum Lycopersicum Fruit/Leaf/Stem Extract
AstringentMolasses Extract
Skin ConditioningSqualane
EmollientHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingPolysorbate 20
EmulsifyingHordeum Distichon Extract
Skin ProtectingPolygonum Cuspidatum Root Extract
AntioxidantLaminaria Digitata Extract
Skin ProtectingTocopheryl Acetate
AntioxidantCaprylyl Glycol
EmollientSodium Hyaluronate
HumectantTetrahexyldecyl Ascorbate
AntioxidantDipotassium Glycyrrhizate
HumectantDi-C12-18 Alkyl Dimonium Chloride
Skin ConditioningTromethamine
BufferingPolysorbate 60
EmulsifyingAmmonium Acryloyldimethyltaurate/Vp Copolymer
Glycyrrhetinic Acid
Skin ConditioningSodium Hydroxide
BufferingHexylene Glycol
EmulsifyingSilica
AbrasivePhenoxyethanol
PreservativeCI 77891
Cosmetic ColorantEssential Oils
Water, Dimethicone, Isododecane, Cyclopentasiloxane, Polysilicone-11, Butylene Glycol, Ascorbyl Glucoside, PEG-10 Dimethicone, Citrus Aurantium Dulcis Peel Oil, Pelargonium Graveolens Oil, Cananga Odorata Flower Oil, Eugenia Caryophyllus Bud Oil, Rosa Damascena Flower Oil, Jasminum Officinale Oil, Viola Odorata Flower/Leaf Extract, Polianthes Tuberosa Extract, Citronellol, Geraniol, Benzyl Benzoate, Eugenol, PEG-6, Rosa Roxburghii Fruit Extract, Paeonia Albiflora Root Extract, Gentiana Lutea Root Extract, Hordeum Vulgare Extract, Triticum Vulgare Germ Extract, Hydrolyzed Rice Bran Extract, Algae Extract, Salicylic Acid, Cholesterol, Glycerin, Solanum Lycopersicum Fruit/Leaf/Stem Extract, Molasses Extract, Squalane, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polysorbate 20, Hordeum Distichon Extract, Polygonum Cuspidatum Root Extract, Laminaria Digitata Extract, Tocopheryl Acetate, Caprylyl Glycol, Sodium Hyaluronate, Tetrahexyldecyl Ascorbate, Dipotassium Glycyrrhizate, Di-C12-18 Alkyl Dimonium Chloride, Tromethamine, Polysorbate 60, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Glycyrrhetinic Acid, Sodium Hydroxide, Hexylene Glycol, Silica, Phenoxyethanol, CI 77891, Essential Oils
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Algae Extract is one of the vaguest names on any label because it just means "extract of some alga" (and there are thousands of species and dozens of ways to extract them). This just means two products listing it can contain completely different things.
This ingredient name was actually officially retired in the INCI dictionary in 2015 and brands were pushed toward species-specific names instead (like Laminaria Digitata Extract or Chondrus Crispus Extract).
Generally, it is used to hold water and soften skin in a formula. Algae are rich in polysaccharides, pigments, and amino-acids that act as humectants, emollients, and skin-conditioning agents.
It isn't on standard cosmetic-patch test panels and "seaweed dermatitis" is actually an acute irritant reaction to algal toxins in seawater and not the cosmetic ingredient.
You'll see algae listed as a 5/5 on a lot of pore-clogging charts and that number doesn't come from anywhere; it's not in the original rabbit-ear studies that most comedogenic ratings trace back to.
The reasoning behind the reputation is that seaweed is high in iodine and iodine can trigger acne-like breakouts when eaten. This traces back to a 1976 letter in Archives of Dermatology describing two women whose breakouts cleared after they stopped taking high-dose kelp supplements orally.
And the reaction of these two women wasn't clogged pores at all: it was an iodine-triggered pustular rash. Later research found normal dietary iodine doesn't meaningfully affect acne either and nobody has shown topical algae delivers enough iodine to matter.
What we do have is dozens of brown and red algae ingredients found to be non-irritating and non-sensitizing, and a handful of studies that found algae compounds may actually help acne.
However, plenty of people do report breaking out from algae-containing products. Skin is individual and it's worth avoiding if yours has reacted to algae before.
Learn more about Algae ExtractButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolCitronellol is used to add fragrance/parfum to a product. It is often derived from plants such as roses. In fact, it can be found in many essential oils including geranium, lavender, neroli, and more. The scent of Citronellol is often described as "fresh, grassy, and citrus-like".
Since the Citronellol molecule is already unstable, Citronellol becomes irritating on the skin when exposed to air.
Citronellol is a modified terpene. Terpenes are unsaturated hydrocarbons found in plants. They make up the primary part of essential oils.
Citronellol is not able to be absorbed into deeper layers of the skin. It has low permeability,
Citronellol is also a natural insect repellent.
Learn more about CitronellolGeraniol is used to add fragrance/parfum to a product. It is the main component of citronellol. It is a monoterpenoid and an alcohol.
Monoterpenes are naturally found in many parts of different plants.
Geraniol can be found in many essential oils including Rose Oil and Citronella Oil. The scent of Geraniol is often described as "rose-like". Many foods also contain Geraniol for fruit flavoring.
Geraniol can irritate the skin when exposed to air. However, irritation depends on the ability of geraniol to penetrate into the skin. In general, geraniol is not able to penetrate skin easily.
Geraniol is colorless and has low water-solubility. However, it is soluble in common organic solvents.
Like citronellol, it is a natural insect repellent.
2,6-Octadien-1-ol, 3,7-dimethyl-, (2E)-
Learn more about GeraniolGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinHexylene Glycol is a multitasker ingredient that works as a solvent, humectant, emulsifier, viscosity reducer, and preservative booster.
It is able to dissolve both water and oil-soluble ingredients to stabilize tricky actives and make products spread more easily.
As a humectant, it pulls water into the skin. But it's a pretty minor moisturizing ingredient compared to other humectants, like glycerin.
Interestingly, it can act as a mild penetration enhancer. One in vitro study on human skin found a 12% concentration upped the absorption of mometasone furoate (a medicinal ingredient used to treat inflammatory skin conditions) up to 7%.
This ingredient is typically used at levels of 0.1-10% depending on the role it's playing.
A patch test study on eczema patients didn't find a significant increase in irritation versus the control group, but the potential for irritation rises at higher concentrations.
Learn more about Hexylene GlycolWe don't have a description for Molasses Extract yet.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolPolysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.
It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.
The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.
Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).
True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.
Because it is derived from lauric acid, it may not be fungal acne safe.
Learn more about Polysorbate 20Rosa Damascena Flower Oil is an essential oil made from the Damask Rose. It is often used as a fragrance in cosmetics.
Rose Oil has antibacterial and antioxidant properties due to its terpene, glycoside, flavonoid, anthocyanin, and Vitamin C content.
Other major parts of Rose Oil include citronellol and geraniol. Both of these are known EU allergens and cause contact-allergies.
The downsides of this ingredient outweight the positives.
Learn more about Rosa Damascena Flower OilSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateTocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Learn more about Tocopheryl AcetateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water