Clinique Smart Clinical Repair Wrinkle Correcting Serum Versus Shiseido Vital Perfection LiftDefine Radiance Serum
Updated on June 28, 2024
Overview
What they are
These products are both reef safe serums. They have a total of 12 ingredients in common
Cool Features
They both contain Vitamin C and Vitamin E
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, reducing pores, scar healing and better texture
Free From
They both do not contain any parabens or sulfates
What's Inside
They both contain silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Clinique Smart Clinical Repair Wrinkle Correcting Serum 53 ingredients
Shiseido Vital Perfection LiftDefine Radiance Serum 55 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
Clinique Smart Clinical Repair Wrinkle Correcting Serum 53 ingredients
Shiseido Vital Perfection LiftDefine Radiance Serum 55 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningDimethicone
Emollient
Isododecane
EmollientButylene Glycol
Humectant
Glycerin
Humectant
Polysilicone-11
Ascorbyl Glucoside
Antioxidant
Sodium Hyaluronate
Humectant
Tocopheryl Acetate
Antioxidant
Squalane
Emollient
Hypnea Musciformis Extract
Skin ProtectingGelidiella Acerosa Extract
Skin ProtectingSigesbeckia Orientalis Extract
Skin ConditioningHelianthus Annuus Seed Extract
Skin Conditioning
Hordeum Vulgare Extract
EmollientTriticum Vulgare Germ Extract
Skin ConditioningCucumis Sativus Fruit Extract
Emollient
Caffeine
Skin Conditioning
Acetyl Hexapeptide-8
Humectant
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Palmitoyl Hexapeptide-12
Skin Conditioning
PEG-10 Dimethicone
Skin Conditioning
Glycyrrhetinic Acid
Skin ConditioningLactis Proteinum
Skin ConditioningIsohexadecane
EmollientPropylene Glycol Dicaprate
EmollientCaprylyl Glycol
EmollientHydroxypinacolone Retinoate
Skin Conditioning
Acetyl Glucosamine
Skin ConditioningCholesterol
Emollient
PEG-8
HumectantYeast Extract
Skin Conditioning
PEG-6
HumectantDimethyl Isosorbide
SolventGlyceryl Polymethacrylate
Polysorbate 20
Emulsifying
Sodium Phosphate
BufferingSynthetic Fluorphlogopite
Polysorbate 80
Emulsifying
Carbomer
Emulsion StabilisingHexylene Glycol
EmulsifyingAmmonium Acryloyldimethyltaurate/Vp Copolymer
Acrylamide/Sodium Acryloyldimethyltaurate Copolymer
Emulsion StabilisingPotassium Hydroxide
BufferingTin Oxide
Abrasive
Disodium Phosphate
BufferingCitric Acid
Buffering
Disodium EDTA
Sodium Citrate
BufferingPhenoxyethanol
Preservative
Potassium Sorbate
Preservative
CI 77891
Cosmetic ColorantWater, Dimethicone, Isododecane, Butylene Glycol, Glycerin, Polysilicone-11, Ascorbyl Glucoside, Sodium Hyaluronate, Tocopheryl Acetate, Squalane, Hypnea Musciformis Extract, Gelidiella Acerosa Extract, Sigesbeckia Orientalis Extract, Helianthus Annuus Seed Extract, Hordeum Vulgare Extract, Triticum Vulgare Germ Extract, Cucumis Sativus Fruit Extract, Caffeine, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, PEG-10 Dimethicone, Glycyrrhetinic Acid, Lactis Proteinum, Isohexadecane, Propylene Glycol Dicaprate, Caprylyl Glycol, Hydroxypinacolone Retinoate, Acetyl Glucosamine, Cholesterol, PEG-8, Yeast Extract, PEG-6, Dimethyl Isosorbide, Glyceryl Polymethacrylate, Polysorbate 20, Sodium Phosphate, Synthetic Fluorphlogopite, Polysorbate 80, Carbomer, Hexylene Glycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Potassium Hydroxide, Tin Oxide, Disodium Phosphate, Citric Acid, Disodium EDTA, Sodium Citrate, Phenoxyethanol, Potassium Sorbate, CI 77891
Water
Skin ConditioningDipropylene Glycol
MaskingDimethicone
Emollient
Glycerin
Humectant
Butylene Glycol
Humectant
Behenyl Alcohol
Emollient
Maltitol
HumectantTriethylhexanoin
MaskingPotassium Methoxysalicylate
BleachingPolyvinyl Alcohol
PEG/PPG-14/7 Dimethyl Ether
Skin ConditioningPhenoxyethanol
Preservative
Trimethylsiloxysilicate
Emollient
Batyl Alcohol
EmollientBehenic Acid
Cleansing
PEG-60 Glyceryl Isostearate
PEG-10 Dimethicone
Skin Conditioning
Parfum
Masking
Phytosteryl/Octyldodecyl Lauroyl Glutamate
Skin ConditioningDisodium EDTA
Myristyl Myristate
Emollient
Tocopheryl Acetate
Antioxidant
Rosa Damascena Flower Water
Masking
Potassium Hydroxide
BufferingSodium Citrate
Buffering2-O-Ethyl Ascorbic Acid
Skin Conditioning
Alcohol
Antimicrobial
Caffeine
Skin Conditioning
Citric Acid
Buffering
Lavandula Angustifolia Oil
Masking
Sodium Metaphosphate
BufferingPPG-3 Dipivalate
Skin ConditioningLimonene
Perfuming
Hexyl Cinnamal
Perfuming
Linalool
Perfuming
Tocopherol
Antioxidant
Glucosamine Hcl
Citronellol
Perfuming
Lilium Candidum Bulb Extract
Skin ConditioningSodium Metabisulfite
Antioxidant
Angelica Acutiloba Root Extract
Skin ConditioningAngelica Keiskei Leaf/Stem Extract
Skin ConditioningOlea Europaea Leaf Extract
Perfuming
Lamium Album Flower/Leaf/Stem Extract
Skin ConditioningCamellia Sinensis Leaf Extract
Antimicrobial
Inositol
Humectant
Carthamus Tinctorius Flower Extract
Skin ConditioningCI 77492
Cosmetic ColorantZiziphus Jujuba Fruit Extract
Skin ConditioningCI 77491
Cosmetic ColorantRosmarinus Officinalis Leaf Extract
AntimicrobialCellulose
AbsorbentNasturtium Officinale Leaf/Stem Extract
Skin ConditioningCinnamomum Cassia Bark Extract
Masking
Bupleurum Falcatum Root Extract
Skin ConditioningWater, Dipropylene Glycol, Dimethicone, Glycerin, Butylene Glycol, Behenyl Alcohol, Maltitol, Triethylhexanoin, Potassium Methoxysalicylate, Polyvinyl Alcohol, PEG/PPG-14/7 Dimethyl Ether, Phenoxyethanol, Trimethylsiloxysilicate, Batyl Alcohol, Behenic Acid, PEG-60 Glyceryl Isostearate, PEG-10 Dimethicone, Parfum, Phytosteryl/Octyldodecyl Lauroyl Glutamate, Disodium EDTA, Myristyl Myristate, Tocopheryl Acetate, Rosa Damascena Flower Water, Potassium Hydroxide, Sodium Citrate, 2-O-Ethyl Ascorbic Acid, Alcohol, Caffeine, Citric Acid, Lavandula Angustifolia Oil, Sodium Metaphosphate, PPG-3 Dipivalate, Limonene, Hexyl Cinnamal, Linalool, Tocopherol, Glucosamine Hcl, Citronellol, Lilium Candidum Bulb Extract, Sodium Metabisulfite, Angelica Acutiloba Root Extract, Angelica Keiskei Leaf/Stem Extract, Olea Europaea Leaf Extract, Lamium Album Flower/Leaf/Stem Extract, Camellia Sinensis Leaf Extract, Inositol, Carthamus Tinctorius Flower Extract, CI 77492, Ziziphus Jujuba Fruit Extract, CI 77491, Rosmarinus Officinalis Leaf Extract, Cellulose, Nasturtium Officinale Leaf/Stem Extract, Cinnamomum Cassia Bark Extract, Bupleurum Falcatum Root Extract
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterDimethicone is a type of synthetic silicone created from natural materials such as quartz.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateCaffeine is most associated with coffee, tea, and cacao. In skincare, it helps with calming inflammation and is rich in antioxidants.
While caffeine is used to treat cellulite and and dark circles, further studies are needed to prove this. It has been believed to help with these skin conditions due to its ability to dilate blood vessels and increase blood flow.
Some studies are looking into caffeine's ability to protect against UV rays.
Learn more about CaffeinePeg-10 Dimethicone is silicone with conditioner and emulsifier properties. It mostly acts as an emollient in skincare and and humectant in haircare.
According to the manufacturer, acidic formulations decrease the stability of this ingredient. It works best in neutral or near neutral formulations.
Potassium hydroxide is commonly known as caustic potash. It is used to fix the pH of a product or as a cleaning agent in soap. In cleansers, it is used for the saponification of oils.
Sapnification is the process of creating fatty acid metal salts from triglycerides and a strong base. During this process, Potassium Hydroxide is used up and is not present in the final product.
Using high concentrations of Potassium Hydroxide have shown to irritate the skin.
Learn more about Potassium HydroxideCitric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.
If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.
Read more about some other popular AHA's here:
Learn more about Citric AcidDisodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTASodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.
Its main functions are to maintain the pH of a product and neutralize metal ions.
The acidity of our skin is maintained by our glands and skin biome; normal pH level of skin is slightly acidic (~4.75-5.5).
Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.
Learn more about Sodium CitratePhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Ingredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Clinique Smart Clinical Repair Wrinkle Correcting Serum 53 ingredients
Shiseido Vital Perfection LiftDefine Radiance Serum 55 ingredients
Reviews
Here's what our community thinks
Clinique Smart Clinical Repair Wrinkle Correcting Serum 53 ingredients
I still try tretinion every now and again. I've never made it past 3 days a week before the flakes set in. So I use other serums like this one from Clinique. I really love this because I don't have to be as concserned with getting it in my hairline, in the small folds on the each side of my nostrils. I can put it on day (I always use sunscreen) and night and it does knock the edges off any Show more
