Beauté Pacifique Crème Symphonique Night-Time
A night moisturizer with 65 ingredients, including vitamin C, retinoid, and niacinamide.
This anti-aging night moisturizer is formulated around Niacinamide and Bakuchiol to soften the look of wrinkles and refine skin texture.
Worth noting
Contains a retinoid, which is best introduced gradually.
We independently verify ingredients, backed by peer-reviewed research. Suggest an update.
What's inside
Ingredients List
Water
Skin ConditioningGlycerin
HumectantSqualane
EmollientGlyceryl Stearate
EmollientArgania Spinosa Kernel Oil
EmollientButyrospermum Parkii Butter Extract
Skin ConditioningPolysorbate 60
EmulsifyingNiacinamide
SmoothingCetearyl Alcohol
EmollientTridecyl Stearate
EmollientDiethylhexyl Succinate
EmollientPEG-100 Stearate
SurfactantTridecyl Trimellitate
EmollientDimethyl Isosorbide
SolventBehenyl Alcohol
EmollientBakuchiol
AntimicrobialRetinyl Palmitate
Skin ConditioningRetinyl Acetate
Skin ConditioningRetinyl Linoleate
Skin ConditioningHydroxypinacolone Retinoate
Skin ConditioningRetinol
Skin ConditioningRetinal
Skin ConditioningBis(Cyano Butylacetate) Anthracenediylidene
Skin ConditioningBeta-Sitosterol
Emulsion StabilisingMarrubium Vulgare Extract
Skin ConditioningAnigozanthos Flavidus Extract
Skin ConditioningCrocus Sativus Flower Extract
MaskingPapain
Skin ConditioningSodium Ursolate
Skin ConditioningSerenoa Serrulata Fruit Extract
Skin ConditioningSodium Oleanolate
Skin ConditioningSesamum Indicum Seed Oil
EmollientDipentaerythrityl Hexacaprylate/Hexacaprate
EmulsifyingArachis Hypogaea Oil
Skin ConditioningCaprylic/Capric Triglyceride
MaskingCaprylyl Glycol
Emollient1,2-Hexanediol
Skin ConditioningHordeum Vulgare Cera
EmollientTocopheryl Acetate
AntioxidantTocopherol
AntioxidantCarnosic Acid
AntioxidantAscorbic Acid
AntioxidantStearic Acid
CleansingCeteth-20 Phosphate
CleansingPEG-20 Stearate
EmulsifyingDicetyl Phosphate
EmulsifyingPolyvinyl Alcohol
Xanthan Gum
EmulsifyingPhenoxyethanol
PreservativeEthylhexylglycerin
Skin ConditioningSodium Benzoate
MaskingPotassium Sorbate
PreservativeMethylpropanediol
SolventPhenylpropanol
MaskingCarbomer
Emulsion StabilisingPolyurethane Crosspolymer-1
Butylene Glycol
HumectantTetrasodium Iminodisuccinate
Phospholipids
Skin ConditioningAlgin
MaskingSodium Lactate
BufferingCitric Acid
BufferingSodium Phosphate
BufferingDisodium Phosphate
BufferingParfum
MaskingWater, Glycerin, Squalane, Glyceryl Stearate, Argania Spinosa Kernel Oil, Butyrospermum Parkii Butter Extract, Polysorbate 60, Niacinamide, Cetearyl Alcohol, Tridecyl Stearate, Diethylhexyl Succinate, PEG-100 Stearate, Tridecyl Trimellitate, Dimethyl Isosorbide, Behenyl Alcohol, Bakuchiol, Retinyl Palmitate, Retinyl Acetate, Retinyl Linoleate, Hydroxypinacolone Retinoate, Retinol, Retinal, Bis(Cyano Butylacetate) Anthracenediylidene, Beta-Sitosterol, Marrubium Vulgare Extract, Anigozanthos Flavidus Extract, Crocus Sativus Flower Extract, Papain, Sodium Ursolate, Serenoa Serrulata Fruit Extract, Sodium Oleanolate, Sesamum Indicum Seed Oil, Dipentaerythrityl Hexacaprylate/Hexacaprate, Arachis Hypogaea Oil, Caprylic/Capric Triglyceride, Caprylyl Glycol, 1,2-Hexanediol, Hordeum Vulgare Cera, Tocopheryl Acetate, Tocopherol, Carnosic Acid, Ascorbic Acid, Stearic Acid, Ceteth-20 Phosphate, PEG-20 Stearate, Dicetyl Phosphate, Polyvinyl Alcohol, Xanthan Gum, Phenoxyethanol, Ethylhexylglycerin, Sodium Benzoate, Potassium Sorbate, Methylpropanediol, Phenylpropanol, Carbomer, Polyurethane Crosspolymer-1, Butylene Glycol, Tetrasodium Iminodisuccinate, Phospholipids, Algin, Sodium Lactate, Citric Acid, Sodium Phosphate, Disodium Phosphate, Parfum
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinSqualane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Learn more about SqualaneGlyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearateYou may know this ingredient as argan oil. It has emollient and skin conditioning properties that help soften skin and reinforce the lipid barrier.
The fatty acid profile of argan oil is roughly 45-55% oleic acid, 28-36% linoleic acid, 10-15% palmitic acid, and 5-7% stearic acid. It also contains vitamin E, sterols, squalene, and polyphenols like ferulic acid.
Two clinical studies in postmenopausal women found that applying argan oil for 60 days significantly improved skin elasticity and moisturization (reduced transepidermal water loss and increased epidermal water content).
Since it is high in oleic and linoleic acid, this ingredient may not be fungal acne safe. Both of these fall in the C11-C24 range that Malassezia yeast can metabolize.
Learn more about Argania Spinosa Kernel OilButyrospermum Parkii Butter Extract is from the fruit of the Shea Tree. It is an effective skin hydrator and emollient.
Shea butter is rich in antioxidants. Antioxidants help fight free-radicals, or molecules that may harm the body. It is also full of fatty acids including stearic acid and linoleic acid. These acids help replenish the skin and keep skin moisturized.
Polysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.
Polysorbate 60 is sorbitol-based and created from the ethoxylation of sorbitan. Ethoxylation is a chemical reaction used to add ethylene oxide. Sorbitan is a the dehydrated version of sorbitol, a sugar found in fruits.
In this case, the 60 comes from reacting 60 units of ethylene oxide with sorbitan.
Polysorbates are commonly used in medicine and foods.
Learn more about Polysorbate 60Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideCetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Learn more about Cetearyl AlcoholTridecyl Stearate isn't fungal acne safe.
Diethylhexyl Succinate comes from succinic acid and 2-ethylhexyl alcohol.
It is a synthetic emollient.
Peg-100 Stearate is an emollient and emulsifier. As an emollient, it helps keep skin soft by trapping moisture in. On the other hand, emulsifiers help prevent oil and water from separating in a product.
PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.
Tridecyl Trimellitate is a synthetic ingredient with emollient and skin conditioning properties. It also acts as a texture enhancer and helps products spread easily without feeling greasy.
As an emollient, it forms a light layer on the skin that keeps moisture in and improves water resistance. This is why you'll often find this ingredient in eye creams and other rich treatments.
This ingredient is seen as the elegant alternative to mineral oil.
Learn more about Tridecyl TrimellitateDimethyl Isosorbide (often shortened to DMI) is a sugar-derived solvent made from sorbitol. It's used to dissolve tricky ingredients and help them mix smoothly into a formula.
Many actives sit as gritty crystals when undissolved, so DMI swoops in to full dissolve them. This helps improve texture, stability, and how evenly an active is distributed.
It does have a penetration-enhancing reputation that is a bit more nuanced than marketing suggests; a cell study on human skin found that 10% DMI didn't significantly boost the permeation of Hydroquinone, Salicylic Acid, or Octadecenedioic Acid compared to controls (though it did improve their solubility in the formula itself).
Typical usage concentrations usually range from 1-10% depending on the formula's needs; this ingredient is also well tolerated at these levels.
Learn more about Dimethyl IsosorbideBehenyl Alcohol is a type of fatty alcohol (these are different from the drying, solvent alcohols).
Fatty Alcohols have hydrating properties and are most often used as an emollient or to thicken a product. They are usually derived from natural fats and oils; behenyl alcohol is derived from the fats of vegetable oils.
Emollients help keep your skin soft and hydrated by creating a film that traps moisture in.
In 2000, Behenyl Alcohol was approved by the US as medicine to reduce the duration of cold sores.
Learn more about Behenyl AlcoholBakuchiol is a plant-derived antioxidant from the seeds of the Psoralea corylifolia plant. It has antimicrobial, emollient, skin conditioning, and antioxidant properties.
You'll likely see it called a "retinol replacement" but the two are technically not related. This is because bakuchiol is able to flip many of the same switches in your skin cells to tell them to:
1) produce more collagen (type I, III, and IV)
2) activate the same genes retinoids do
Unlike retinoids, this ingredient will not increase photosensitivity and is safe to use during pregnancy (but please still check in with your doctor!).
The flagship clinical trial from Dhaliwal et al. 2019 found 0.5% bakuchiol (twice daily) and 0.5% retinol (once daily) reduced wrinkles and hyperpigmentation equally, but bakuchiol had significantly less irritation.
Systematic reviews also back this up:
Bakuchiol is comparable to retinol for photoaging but with better tolerability. It also has mild antibacterial properties against Cutibacterium acnes and antifungal activity in vitro against Candida and dermatophytes.
The reason bakuchiol works well is due to its structure; it is a meroterpene phenol, or a hybrid molecule. The phenol half acts as an antioxidant while the terpene half is fat-loving. This helps the molecule slip through the skin barrier.
This ingredient is usually used between 0.5-2%. Only one case of contact dermatitis has ever been reported for this ingredient.
Learn more about BakuchiolRetinyl Palmitate is a form of retinoid. Retinoids are the superstar class of anti-aging ingredients that include Tretinoin and Retinol.
This particular ingredient has had a bumpy year with its rise and fall in popularity.
First, Retinyl Palmitate is created from Palmitic Acid and Retinol. It is a Retinol ester and considered one of the weaker forms of retinoid.
This is because all retinoids have to be converted to Tretinoin, AKA Retinoic Acid.
Retinyl Palmitate is pretty far down the line and has to go through multiple conversions before its effects are seen. Once it's on your skin, enzymes called esterases convert it into Retinol, then into Retinal, and finally into Retinoic Acid; that's three steps with a little lost at each one.
The benefits of Retinyl Palmitate are debated due to this long and ineffective conversion line.
So why use it at all?
The answer is stability. Retinol and Retinoic Acid break down fast when they hit light, heat, and air, and Retinoic Acid can be pretty irritating on top of that.
Retinyl Palmitate is much more stable and gentler, making it easier to formulate with and easier on sensitive skin (even if it's weaker gram for gram).
Studies show Retinyl Palmitate to help:
Newer research from 2023-2025 also found that Retinyl Palmitate works especially well when paired with Retinol. The two seem to cover each other's weak spots; retinol brings the potency while Retinyl Palmitate brings the stability and gentleness. Together, they repair UV damage better than either one does alone.
This ingredient used to be found in sunscreens to boost the efficacy of sunscreen filters.
The downfall of Retinyl Palmitate was due to released reports about the ingredient being correlated to sun damage and skin tumors.
Most of this traces back to a 2012 US National Toxicology Program (NTP) study where hairless mice coated in Retinyl Palmitate cream and exposed to UV light developed skin tumors faster.
Here's the nuance, though.
When the Cosmetic Ingredient Review (CIR) Expert Panel went back through that study, they found methodological flaws and decided the results couldn't be interpreted as proof of extra risk.
The EU's Scientific Committee on Consumer Safety (SCCS) said the mouse findings might point to a concern but they're hard to apply to humans since hairless mouse skin and human skin behave differently.
While there is a study showing this ingredient to cause DNA damage when exposed to UVA, there is no concrete proof of it being linked to skin cancer. It is completely safe to use when used correctly.
Both the CIR and the SCCS consider it safe at the concentrations used in cosmetics; the SCCS specifically cleared retinoids up to 0.05% in body lotions and 0.3% in face creams, hand creams, and rinse-off products.
As of 2025, the EU has written those limits into law, plus a label warning about your total Vitamin A intake from all sources.
All retinoids increase your skin's sensitivity to the sun in the first few months of usage. Be especially careful with reapplying sunscreen when using any form of retinoid.
One more note: if you're pregnant, high doses of Vitamin A can be a concern, so a lot of people skip topical retinoids (including Retinyl Palmitate) during pregnancy just to be safe. Check with your doctor if you're unsure.
Fun fact: This ingredient is often added to low-fat milk to increase the levels of Vitamin A.
Learn more about Retinyl PalmitateRetinyl Acetate is part of the retinoid family. It is made from retinol and acetic acid.
Though retinyl acetate is more stable than retinol, it is also less effective and less irritating. This is due to the conversion line all retinoids have to go through.
All retinoids must be converted to retinoic acid. The further away from this end result, the less effective the ingredient is.
Fun fact: Retinyl acetate is commonly used as a Vitamin C additive for foods.
Learn more about Retinyl AcetateRetinyl Linoleate is a form of retinoid and isn't fungal acne safe. It can be good for oily skin. It can help to reduce the visibility of dark spots, heal scars, and brighten skin.
Hydroxypinacolone Retinoate (aka Granactive Retinoid or HPR) is a retinoid that is part of the same vitamin A family as retinol.
It is an ester of retinoic acid that binds directly to your skin's retinoic acid receptors so it doesn't need your skin to convert it through several steps before it can do anything.
In practice, this means it does the classic retinoid jobs in a formula:
The best part is that it can do all this with noticeably less redness, flaking, and stinging than traditional retinoids.
That gentle reputation is backed by lab work as well; a 2018 study on skin models found that HPR triggered higher retinoid-gene activity than retinol, retinal, or retinyl propionate at the same concentrations while being less irritating to cells.
It also boosted procollagen production to levels similar to retinoic acid itself.
A 2023 study showed HPR works synergistically with retinyl propionate to switch on collagen-building pathways and a 2025 clinical serum study in women with mild photoaging saw improvements in wrinkles and elasticity (though that formula also contained retinol, peptides, and Silybin).
One naming quirk worth mentioning:
You'll likely see this ingredient sold under the trade name "Granactive Retinoid", which is actually only 10% HPR blended with 90% Dimethyl Isosorbide solvent. This means a 5% Granactive Retinoid really only means about 0.5% HPR.
Finished products typically land somewhere between 0.05-1% and it's happiest formulated at a mildly acidic to neutral pH (~5.5-6.5).
Another perk is that this is one of the more light- and temperature-stable retinoids which is a nice bonus for shelf life.
Learn more about Hydroxypinacolone RetinoateRetinol is one of the most studied anti-aging ingredients in skincare (and for good reason!).
It's a form of vitamin A that your skin converts into Retinoic Acid, the active molecule that actually does the work in your cells.
That conversion happens in two steps: your skin first turns Retinol into Retinaldehyde (also called Retinal), then turns Retinaldehyde into Retinoic Acid.
Retinol is converted to biologically active retinoic acid via retinaldehyde by dehydrogenases in a two-step oxidation process.
Each step is a little "upgrade" toward the active form which is part of why Retinol is gentler than prescription Retinoic Acid; your skin does the work gradually. This also explains where Retinol sits in the retinoid family.
Here is the retinoid family ranked roughly by strength: Retinyl Esters (like Retinyl Palmitate) < Retinol < Retinaldehyde < Retinoic Acid.
Retinoid activity increases in that order, while tolerance runs in reverse; retinyl esters are the gentlest and retinoic acid the most irritating.
The more conversion steps an ingredient needs, the gentler (and slower) it tends to be, so Retinol lands in a nice middle spot. It's more effective than the esters, gentler than prescription options.
Once it becomes Retinoic Acid, it binds to receptors inside your cells' nuclei (called RARs and RXRs). These receptor pairs bind to specific DNA motifs called retinoic acid response elements and act like switches that turn certain genes on or off.
In practice, this means a few things happen in a formula. It:
That last two are worth a closer look.
A study that tested Retinol directly (not just prescription Retinoic Acid) found that four weeks of retinol thickened the epidermis and switched on the genes for Collagen I and Collagen III, with more procollagen I and III showing up in the skin. And after twelve weeks, facial wrinkles were visibly reduced.
Retinoids more broadly stimulate the skin's synthesis of hyaluronan and other glycosaminoglycans, part of what gives skin a plumper, more hydrated look over time.
So even the gentler OTC form is doing real structural work (not just sitting on the surface).
It's also worth knowing Retinol isn't only a wrinkle ingredient; it can help with uneven tone, dark spots, rough texture, and the look of pores as well because it speeds up turnover and influences pigment.
The research backs this up as well.
A pooled analysis of six clinical studies found that 0.1% stabilized retinol improved all signs of photoaging versus vehicle as early as week 4 and through 12 weeks, with only a few mild cases of irritation.
Another study comparing concentrations found that 0.3% and 1% Retinol were similarly effective at remodeling photodamaged skin, but 0.3% caused fewer adverse reactions when used daily (a useful reminder that more isn't always better).
Retinol is about tenfold less potent than Retinoic Acid. This is why it works as a gentler, non-prescription option that builds results over time.
Typical concentrations range from 0.1-1%, with 0.1% to 0.3% being a well-supported sweet spot for visible benefits with good tolerability.
One quirk worth mentioning: Retinol is famously unstable.
It's highly sensitive to light and oxygen, and UV exposure breaks it down into a range of degradation products.
Real-world testing bears this out, with retinoid content in some products dropping anywhere from 0% to 80% after six months at room temperature, and even more at higher temperatures.
This is why good formulations lean on opaque, air-tight packaging (think tubes and pumps, not clear jars) and often "encapsulate" the Retinol to shield it.
Signs of oxidation include your product turning yellow or smelling "off". Keeping it somewhere cool and dark, and using it up within a few months of opening helps it stay effective.
The most common side effects are mild and temporary: usually some dryness, redness, or light peeling as your skin adjusts. These tend to settle with consistent and lower-frequency use.
Like all retinoids, Retinol works best with nightly use, a good moisturizer, and daytime sunscreen.
The "ramp up" method works well: start with Retinol once a week to give your skin time to adjust, which keeps irritation low. Slowly add more nights until you reach your goal frequency once your skin feels comfortable.
Retinoids also make your skin more sensitive to the sun in the first few weeks, so wear sunscreen every morning and protect your skin from direct sun while you build up tolerance.
One safety note: topical Retinoids aren't recommended during pregnancy or breastfeeding. Systemic absorption from creams is low but because high oral vitamin A is a known teratogen and topical safety data are limited, most clinicians recommend stopping retinoids when pregnant or trying to conceive.
Learn more about RetinolRetinal (aka retinaldehyde) is a form of retinoid that formulators use mainly as an antiaging and skin-renewing active.
What makes it special is its position in the retinoid family; skin converts it to retinoic acid (the prescription gold standard) in just one step.
Because retinal only requires 1 conversion step to become retinoic acid, it's the strongest over-the-counter retinoid. It also works at lower concentrations than retinol, since retinal is about 10x more bioavailable.
Studies back up its efficacy in skin:
A foundational trial showed that applying 0.05-0.5% retinal for 1-3 months produced a dose-dependent and significant increase in epidermal thickness + cell turnover markers.
And a head-to-head comparison of 0.05% retinal against a 0.05% retinoid acid found both formulations were effective for the basis of wrinkle/skin roughness features, but retinoic acid caused more local irritation.
More recent controlled trials confirm it improves wrinkles, dermal density, and firmness over 12-24 weeks, with significant improvements in skin texture and firmness (particularly with the higher 0.1% concentration).
Retinal also has one trick the other retinoids do not: it directly fights against acne bacteria since a clinical study showed retinaldehyde-treated areas displayed a significant decrease in counts of viable P. acnes.
This makes it a great pick for people who want to treat aging and breakouts.
Typical cosmetic use sits in the 0.05-0.1% range with 0.05% being the gentle starting point and 0.1% giving stronger results.
Like all retinoids, retinal works best with nightly use, a good moisturizer, and daytime sunscreen. It can cause some irritation so ease into it slowly rather than going all in.
The "ramp up" method works well: start with Retinal once a week to give your skin time to adjust, which keeps irritation low.
Slowly add more nights until you reach your goal frequency once your skin feels comfortable.
Retinoids also make your skin more sensitive to the sun in the first few weeks, so wear sunscreen every morning and protect your skin from direct sun while you build up tolerance.
Learn more about RetinalWe don't have a description for Bis(Cyano Butylacetate) Anthracenediylidene yet.
Beta-Sitosterol is a plant-derived fatty acid with a structure similar to cholesterol (which naturally occurs in skin). It helps hydrate the skin and stabilize formulations.
This ingredient can be naturally found in fruits, veggies, nuts, and seeds.
We don't have a description for Marrubium Vulgare Extract yet.
We don't have a description for Anigozanthos Flavidus Extract yet.
We don't have a description for Crocus Sativus Flower Extract yet.
Papain is a proteolytic enzyme extracted from unripe papaya fruit. It is a gentle exfoliator that helps remove the dead skin cells from your outermost layer of skin.
Basically, papain works by dissolving the "glue" holding dead skin cells to your skin's surface. This also promotes cell turnover and smooths texture.
Unlike other exfoliants, papain can work without causing significant irritation.
Beyond exfoliation, its proteolytic action also helps soothe irritated skin and supports the healing of minor wounds.
A 2024 in vivo/in vitro study confirmed its potential to suppress skin inflammation and improve transepidermal water loss (TEWL) in atopic dermatitis models.
Just one thing worth noting: there are reports of allergic responses in individuals with a papaya or latex sensitivity. Be sure to patch test if you're in this camp.
Learn more about PapainWe don't have a description for Sodium Ursolate yet.
Serenoa Serrulata Fruit Extract can be good for oily skin.
We don't have a description for Sodium Oleanolate yet.
Sesamum Indicum Seed Oil is the cold-pressed oil from sesame seeds.
It is an emollient and skin conditioning agent made up of roughly 82-85% unsaturated fatty acids, mostly linoleic (~41%) and oleic acid (~39%).
This pairing gives it barrier-supporting and moisturizing properties. Linoleic acid, an essential omega-6 fatty acid, can be incorporated into complex skin lipids. Topical application has shown barrier repair, anti-inflammatory, and wound-healing effects in cell and animal studies.
Beyond fatty acids, sesame oil brings something more distinctive to the table:
It contains natural antioxidants sesamol, sesamolin, and gamma-tocopherol. These also give the oil notably high oxidative stability.
One of the oil's key lignans, sesamin, has also demonstrated anti-inflammatory activity in preclinical models.
A 2023 clinical study found that a single application of sesame seed oil to the forearms of 35 healthy women improved stratum corneum hydration (though it didn't outperform raspberry seed oil).
The comedogenic rating of 1-3 depends on the type of sesame oil; unrefined carries a rating of 3 while refined sesame oil drops to a 1.
This ingredient may not be safe for fungal acne as it contains fatty acids that can feed Malassezia.
Learn more about Sesamum Indicum Seed OilWe don't have a description for Dipentaerythrityl Hexacaprylate/Hexacaprate yet.
Arachis Hypogaea Oil is the INCI name for peanut oil.
It's an emollient that contains oleic acid (~57%), linoleic acid (~26%), and small amounts of palmitic, stearic, arachidic, vitamin E, and other types of acids.
In skincare, it mostly softens, smooths, and slows water loss.
For those with a peanut allergy: Cosmetic-grade peanut oil is refined to strip out the proteins that trigger peanut allergies. But always be sure to patch test if you're unsure or have a severe allergy.
Clinical studies have repeatedly found that highly refined peanut oil doesn't cause reactions in the vast majority of peanut-allergic people.
Just know: unrefined or cold pressed version can still contain the allergenic protein.
We recommend reaching out to the brand about their source of peanut oil if you have questions.
Learn more about Arachis Hypogaea OilCaprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl Glycol1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Hordeum Vulgare Cera isn't fungal acne safe.
Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Learn more about Tocopheryl AcetateTocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolCarnosic Acid is an antioxidant.
Ascorbic Acid is is pure Vitamin C and is the biologically active form used directly by skin.
Not only is vitamin C great for your overall health and immune system, but it also has plenty of benefits for your skin. It is best supported by academic literature for:
Topical vitamin C has been shown to help neutralize oxidative stress from UV and pollution, helping to improve photoaging and hyperpigmentation when used consistently.
One clinical study found that using 5% topical vitamin C for six months improved signs of photodamaged skin, both on the surface and in the deeper structural layers of the skin.
While vitamin C doesn’t replace sunscreen, studies show it can boost photoprotection when combined with Vitamin E and ferulic acid. These two ingredients help improve stability and protective effects.
The big downside of this ingredient is formulation difficulty. Vitamin C is prone to oxidation and doesn't penetrate the skin unless formulated correctly. Research found that vitamin C absorbs into the skin best at a low pH (< 3.5) with about 20% being the upper limit for effective absorption.
Skin levels can saturate after repeated application; this means your skin won’t keep absorbing more once it’s full of vitamin C. This is why more isn’t always better with vitamin C and why very high concentrations don’t necessarily give extra benefits.
Ascorbic acid generally works well with many skincare ingredients but can be irritating when combined with other active ingredients. Strong oxidizing acne treatments like benzoyl peroxide can reduce the effectiveness of vitamin C if they are used at the same time; they are often recommended for use at different times of day.
Read more about other types of Vitamin C:
Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.
Learn more about Ascorbic AcidStearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.
In cosmetics, it is a multitasker:
Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.
Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.
Learn more about Stearic AcidWe don't have a description for Ceteth-20 Phosphate yet.
Peg-20 Stearate is produced from stearic acid. It is an emulsifier and humectant.
The 20 stands for the average number of ethylene oxide monomers in the polyethylene chain. The 'p' in 'Peg' stands for this chain.
This ingredient may not be Malassezia folliculitis, or fungal-acne safe.
Learn more about PEG-20 StearateWe don't have a description for Dicetyl Phosphate yet.
We don't have a description for Polyvinyl Alcohol yet.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumPhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoatePotassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Learn more about Potassium SorbateMethylpropanediol is a synthetic solvent and humectant.
As a solvent, it helps dissolve other ingredients, helping to evenly distribute ingredients throughout the product. This ingredient has also been shown to have antimicrobial properties which makes it a preservative booster.
Methylpropanediol is able to add a bit of moisture to the skin. It also helps other ingredients be better absorbed into the skin, such as salicylic acid.
Learn more about MethylpropanediolPhenylpropanol is a fragrance.
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Learn more about CarbomerWe don't have a description for Polyurethane Crosspolymer-1 yet.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolWe don't have a description for Tetrasodium Iminodisuccinate yet.
Phospholipids are a family of skin-identical lipids that makeup the structural backbone of every cell membrane in your body.
In cosmetics, they function as skin conditioning agents with emulsifier and surfactant properties. They're typically sourced from soybean or sunflower lecithin (or sometimes egg yolk or marine sources).
Because they mirror the lipids naturally found in the deeper layers of your skin, topical phospholipids help reinforce the lipid matrix, reduce transepidermal water loss, and leave skin feeling conditioned.
They're also used to form liposomes, or tiny self-assembling vesible used to stabilize actives like vitamin c or retinol. This helps these ingredients integrate into the upper layers of skin more easily.
Phospholipids are compatible with everything and the CIR Expert Panel has concluded them to be safe at current use levels.
Some types of phospholipids include:
Learn more about PhospholipidsAlgin is brown algae. Algae is an informal term for a group of aquatic organisms that can photosynthesize. It is estimated there are at least 30,000 types of Algae.
Algae contains antioxidants. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.
Sodium Lactate is the sodium salt of lactic acid, an AHA. It is a humectant and sometimes used to adjust the pH of a product.
This ingredient is part of our skin's NMF, or natural moisturizing factor. Our NMF is essential for the hydration of our top skin layers and plasticity of skin. NMF also influences our skin's natural acid mantle and pH, which protects our skin from harmful bacteria.
High percentages of Sodium Lactate can have an exfoliating effect.
Fun fact: Sodium Lactate is produced from fermented sugar.
Learn more about Sodium LactateCitric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidSodium Phosphate is is behind-the-scenes formulation helper. Its main job is buffering, or locking in the product's pH.
This helps ensure the formula stays at its intended acidity through manufacturing, shipping, and sitting on your shelf. Many active ingredients like vitamin C or retinoids are pH sensitive so maintaining their happy pH range matters.
It is synthetic and reported use concentrations are very low (up to 0.086% in face powders).
Learn more about Sodium PhosphateDisodium Phosphate is a water-soluble powder used as a pH adjuster and mild chelating agent. It basically holds a specific pH and binds stray metal ions so your product stays stable.
This ingredient is usually used at very low levels and concentrations range from 0.000054% - 2.9%. The CIR Expert Panel states this ingredient to be non-irritating at current use levels.
Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
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