ZO Skin Health Retinol Skin Brightener 0.25% Versus Medik8 Crystal Retinal - 3
Updated on June 18, 2025
Overview
What they are
These products are both cruelty-free and reef safe serums. They have a total of 10 ingredients in common
Cool Features
They both contain exfoliants, retinoid, Vitamin C and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any parabens or sulfates
What's Inside
They both contain common allergens, fragrances and oils
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
ZO Skin Health Retinol Skin Brightener 0.25% 49 ingredients
Medik8 Crystal Retinal 43 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
ZO Skin Health Retinol Skin Brightener 0.25% 49 ingredients
Medik8 Crystal Retinal 43 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningDimethicone
Emollient
Cetearyl Isononanoate
EmollientGlycerin
Humectant
Prunus Amygdalus Dulcis Oil
Skin Conditioning
Cetearyl Alcohol
Emollient
Steareth-20
CleansingPentylene Glycol
Skin ConditioningAscorbyl Glucoside
Antioxidant
Cetyl Alcohol
Emollient
Acrylamide/Ammonium Acrylate Copolymer
Prunus Armeniaca Kernel Oil
Masking
Pelargonium Graveolens Flower Oil
Masking
Lavandula Angustifolia Oil
Masking
Propylheptyl Caprylate
EmollientBakuchiol
Antimicrobial
Acetyl Glucosamine
Skin ConditioningCetearyl Glucoside
EmulsifyingLecithin
Emollient
Polyisobutene
Alcohol
Antimicrobial
Glutathione
Carbomer
Emulsion StabilisingCaprylyl Glycol
EmollientBisabolol
Masking
1,2-Hexanediol
Skin Conditioning
Silica
Abrasive
Polysorbate 20
Emulsifying
Retinol
Skin Conditioning
Polysorbate 80
Emulsifying
Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
Antioxidant
Disodium EDTA
Sorbitan Isostearate
Emulsifying
Gluconolactone
Skin Conditioning
Tocopheryl Acetate
Antioxidant
Sodium Sulfite
Preservative
Sodium Metabisulfite
Antioxidant
Ascorbyl Palmitate
Antioxidant
BHT
Antioxidant
Soy Isoflavones
Skin ConditioningSodium Hydroxide
BufferingPotassium Sorbate
Preservative
Sodium Benzoate
Masking
Linalool
Perfuming
Citronellol
Perfuming
Geraniol
Perfuming
Limonene
Perfuming
Citral
Perfuming
Coumarin
Perfuming
Water, Dimethicone, Cetearyl Isononanoate, Glycerin, Prunus Amygdalus Dulcis Oil, Cetearyl Alcohol, Steareth-20, Pentylene Glycol, Ascorbyl Glucoside, Cetyl Alcohol, Acrylamide/Ammonium Acrylate Copolymer, Prunus Armeniaca Kernel Oil, Pelargonium Graveolens Flower Oil, Lavandula Angustifolia Oil, Propylheptyl Caprylate, Bakuchiol, Acetyl Glucosamine, Cetearyl Glucoside, Lecithin, Polyisobutene, Alcohol, Glutathione, Carbomer, Caprylyl Glycol, Bisabolol, 1,2-Hexanediol, Silica, Polysorbate 20, Retinol, Polysorbate 80, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Disodium EDTA, Sorbitan Isostearate, Gluconolactone, Tocopheryl Acetate, Sodium Sulfite, Sodium Metabisulfite, Ascorbyl Palmitate, BHT, Soy Isoflavones, Sodium Hydroxide, Potassium Sorbate, Sodium Benzoate, Linalool, Citronellol, Geraniol, Limonene, Citral, Coumarin
Water
Skin ConditioningCaprylic/Capric Triglyceride
Masking
Glycerin
Humectant
Isododecane
EmollientCetearyl Olivate
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingCetearyl Alcohol
Emollient
PPG-12/Smdi Copolymer
EmollientSorbitan Olivate
Emulsifying
Tocopheryl Acetate
Antioxidant
Cyclodextrin
AbsorbentSqualane
Emollient
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingHydroxyacetophenone
Antioxidant
3-O-Ethyl Ascorbic Acid
Skin Conditioning
Hydroxypropyl Methylcellulose
Emulsion StabilisingSodium Hyaluronate
Humectant
Phenoxyethanol
Preservative
Tetrahexyldecyl Ascorbate
Antioxidant
Daucus Carota Sativa Seed Oil
Emollient
Retinal
Skin Conditioning
Rubus Chamaemorus Seed Oil
Skin Conditioning
Alumina
Abrasive
Isostearic Acid
Cleansing
Lecithin
Emollient
Polyglyceryl-3 Polyricinoleate
Emulsifying
Lonicera Japonica Flower Extract
Skin ConditioningLonicera Caprifolium Flower Extract
Perfuming
Polyhydroxystearic Acid
Emulsifying
Stearic Acid
Cleansing
Sodium Polyaspartate
HumectantPentylene Glycol
Skin ConditioningCitric Acid
Buffering
Polysorbate 60
Emulsifying
Disodium EDTA
Ethylhexylglycerin
Skin ConditioningBHT
Antioxidant
Sorbitan Isostearate
Emulsifying
Vanilla Planifolia Fruit Extract
Skin Conditioning
Dipteryx Odorata Bean Extract
Masking
Coumarin
Perfuming
CI 14700
Cosmetic ColorantCI 77891
Cosmetic ColorantWater, Caprylic/Capric Triglyceride, Glycerin, Isododecane, Cetearyl Olivate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, PPG-12/Smdi Copolymer, Sorbitan Olivate, Tocopheryl Acetate, Cyclodextrin, Squalane, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydroxyacetophenone, 3-O-Ethyl Ascorbic Acid, Hydroxypropyl Methylcellulose, Sodium Hyaluronate, Phenoxyethanol, Tetrahexyldecyl Ascorbate, Daucus Carota Sativa Seed Oil, Retinal, Rubus Chamaemorus Seed Oil, Alumina, Isostearic Acid, Lecithin, Polyglyceryl-3 Polyricinoleate, Lonicera Japonica Flower Extract, Lonicera Caprifolium Flower Extract, Polyhydroxystearic Acid, Stearic Acid, Sodium Polyaspartate, Pentylene Glycol, Citric Acid, Polysorbate 60, Disodium EDTA, Ethylhexylglycerin, BHT, Sorbitan Isostearate, Vanilla Planifolia Fruit Extract, Dipteryx Odorata Bean Extract, Coumarin, CI 14700, CI 77891
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
BHT is a synthetic antioxidant and preservative.
As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.
As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.
The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.
However, it was recently restricted for use in the UK as of April 2024.
Learn more about BHTCetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.
Cetearyl alcohol is an emollient. Emollients help soothe and hydrate the skin by trapping moisture.
Studies show Cetearyl alcohol is non-toxic and non-irritating. The FDA allows products labeled "alcohol-free" to have fatty alcohols.
This ingredient is usually derived from plant oils such as palm, vegetable, or coconut oils. There is debate on whether this ingredient will cause acne.
Due to the fatty acid base, this ingredient may not be Malassezia folliculitis safe.
Learn more about Cetearyl AlcoholCoumarins are a group of substances found naturally in plants. There are over 1300 types of coumarins identified. It has a natural vanilla scent.
Coumarin is an identified EU known allergy, meaning it may cause an allergic reaction when applied to the skin.
In many countries, coumarin is banned as a food additive. However, it can be found in soaps, tobacco products, and some alcohol drinks.
Plants use coumarins as a chemical defense. Some plants that have coumarins include lavender, tonka beans, and yellow clovers.
Learn more about CoumarinDisodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTAGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinLecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of mixture of phospholipids.
This ingredient has emollient and emulsifying properties.
As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.
As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.
This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.
Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.
We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.
Learn more about LecithinPentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolSorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.
As an emulsifier, Sorbitan Isostearate prevents oils and water from separating.
Due to its isostearic acid base, it may not be safe for Malassezia or fungal acne.
Learn more about Sorbitan IsostearateTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterIngredient Ratings
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ZO Skin Health Retinol Skin Brightener 0.25% 49 ingredients
Medik8 Crystal Retinal 43 ingredients
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