Skinfix Barrier+ Triple Lipid-Peptide Cream Versus Peter Thomas Roth Peptide 21 Wrinkle Resist Serum
This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Ceramide NP to strengthen the skin barrier and hydrate skin.
This anti-aging serum is formulated around Tripeptide-10 Citrulline and Acetyl Octapeptide-3 to soften the look of wrinkles.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningCaprylic/Capric Triglyceride
MaskingGlycerin
HumectantButyrospermum Parkii Butter
Skin ConditioningOlus Oil
EmollientCetyl Lactate
EmollientPropanediol
SolventC12-16 Alcohols
EmollientCaprylyl Caprylate/Caprate
EmollientJojoba Oil/Macadamia Seed Oil Esters
Skin ConditioningGlyceryl Stearate Citrate
EmollientPalmitic Acid
EmollientHydrogenated Lecithin
EmulsifyingOryza Sativa Bran Extract
Skin ConditioningDilinoleic Acid/Propanediol Copolymer
EmollientSqualene
EmollientOphiopogon Japonicus Root Extract
Skin ConditioningXanthan Gum
EmulsifyingPhytosteryl Sunflowerseedate
Skin ConditioningGlycine Soja Extract
Skin ConditioningPentylene Glycol
Skin ConditioningCeramide NP
Skin ConditioningCeramide AP
Skin ConditioningCeramide EOP
Skin ConditioningHydrolyzed Rice Protein
Skin ConditioningChondrus Crispus Extract
Skin ConditioningHydrogenated Vegetable Glycerides
EmollientHelianthus Annuus Extract
EmollientSodium Hyaluronate
HumectantCitric Acid
BufferingPhytosteryl Macadamiate
Skin ConditioningTocopherol
AntioxidantRosmarinus Officinalis Leaf Extract
AntimicrobialAloe Barbadensis Leaf Juice
Skin ConditioningTrisodium Ethylenediamine Disuccinate
Phytosterols
Skin ConditioningSodium Lauroyl Lactylate
EmulsifyingGluconolactone
Skin ConditioningPhenethyl Alcohol
MaskingPhytosphingosine
Skin ConditioningCholesterol
EmollientCarbomer
Emulsion StabilisingPotassium Sorbate
PreservativeEthylhexylglycerin
Skin ConditioningSodium Benzoate
MaskingPhenoxyethanol
PreservativeWater, Caprylic/Capric Triglyceride, Glycerin, Butyrospermum Parkii Butter, Olus Oil, Cetyl Lactate, Propanediol, C12-16 Alcohols, Caprylyl Caprylate/Caprate, Jojoba Oil/Macadamia Seed Oil Esters, Glyceryl Stearate Citrate, Palmitic Acid, Hydrogenated Lecithin, Oryza Sativa Bran Extract, Dilinoleic Acid/Propanediol Copolymer, Squalene, Ophiopogon Japonicus Root Extract, Xanthan Gum, Phytosteryl Sunflowerseedate, Glycine Soja Extract, Pentylene Glycol, Ceramide NP, Ceramide AP, Ceramide EOP, Hydrolyzed Rice Protein, Chondrus Crispus Extract, Hydrogenated Vegetable Glycerides, Helianthus Annuus Extract, Sodium Hyaluronate, Citric Acid, Phytosteryl Macadamiate, Tocopherol, Rosmarinus Officinalis Leaf Extract, Aloe Barbadensis Leaf Juice, Trisodium Ethylenediamine Disuccinate, Phytosterols, Sodium Lauroyl Lactylate, Gluconolactone, Phenethyl Alcohol, Phytosphingosine, Cholesterol, Carbomer, Potassium Sorbate, Ethylhexylglycerin, Sodium Benzoate, Phenoxyethanol
Water
Skin ConditioningGlycerin
HumectantRosa Centifolia Flower Water
Skin ConditioningIsopropyl Myristate
EmollientSqualane
EmollientMannitol
HumectantButylene Glycol
HumectantNatto Gum
Tripeptide-10 Citrulline
Skin ConditioningAcetyl Octapeptide-3
HumectantPalmitoyl Hexapeptide-12
Skin ConditioningAcetyl Tetrapeptide-11
Skin ConditioningAcetyl Hexapeptide-8
HumectantAcetyl Hexapeptide-1
Skin ConditioningPalmitoyl Oligopeptide
CleansingAcetyl Tetrapeptide-9
Skin ConditioningAcetyl Tetrapeptide-2
Skin ConditioningTripeptide-1
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningHexapeptide-11
Skin ConditioningDipeptide Diaminobutyroyl Benzylamide Diacetate
Skin ConditioningPalmitoyl Tripeptide-5
Skin ConditioningTrifluoroacetyl Tripeptide-2
Skin ConditioningPalmitoyl Tripeptide-1
Skin ConditioningSodium Polyglutamate
HumectantSodium Hyaluronate
HumectantTocopheryl Acetate
AntioxidantRetinyl Palmitate
Skin ConditioningAscorbic Acid
AntioxidantHydrolyzed Soy Protein
HumectantHydrolyzed Wheat Protein
Skin ConditioningLecithin
EmollientPseudoalteromonas Ferment Extract
HumectantAcrylates Copolymer
Magnesium Chloride
Polysorbate 20
EmulsifyingDimethyl Isosorbide
SolventAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingLeuconostoc/Radish Root Ferment Filtrate
AntimicrobialPEG-8 Dimethicone
EmulsifyingDisodium Phosphate
BufferingCarbomer
Emulsion StabilisingDextran
Sodium Lactate
BufferingTetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate
Skin ConditioningXanthan Gum
EmulsifyingTriethanolamine
BufferingSodium Phosphate
BufferingOctyldodecanol
EmollientSilica
AbrasiveSodium Propoxyhydroxypropyl Thiosulfate Silica
Sodium Hydroxide
BufferingCaprylyl Glycol
EmollientPotassium Sorbate
PreservativeSodium Benzoate
MaskingPhenoxyethanol
PreservativeWater, Glycerin, Rosa Centifolia Flower Water, Isopropyl Myristate, Squalane, Mannitol, Butylene Glycol, Natto Gum, Tripeptide-10 Citrulline, Acetyl Octapeptide-3, Palmitoyl Hexapeptide-12, Acetyl Tetrapeptide-11, Acetyl Hexapeptide-8, Acetyl Hexapeptide-1, Palmitoyl Oligopeptide, Acetyl Tetrapeptide-9, Acetyl Tetrapeptide-2, Tripeptide-1, Palmitoyl Tetrapeptide-7, Hexapeptide-11, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Tripeptide-5, Trifluoroacetyl Tripeptide-2, Palmitoyl Tripeptide-1, Sodium Polyglutamate, Sodium Hyaluronate, Tocopheryl Acetate, Retinyl Palmitate, Ascorbic Acid, Hydrolyzed Soy Protein, Hydrolyzed Wheat Protein, Lecithin, Pseudoalteromonas Ferment Extract, Acrylates Copolymer, Magnesium Chloride, Polysorbate 20, Dimethyl Isosorbide, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Leuconostoc/Radish Root Ferment Filtrate, PEG-8 Dimethicone, Disodium Phosphate, Carbomer, Dextran, Sodium Lactate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Xanthan Gum, Triethanolamine, Sodium Phosphate, Octyldodecanol, Silica, Sodium Propoxyhydroxypropyl Thiosulfate Silica, Sodium Hydroxide, Caprylyl Glycol, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Learn more about CarbomerGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolPotassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Learn more about Potassium SorbateSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan Gum