Simple Skincare Regeneration Age Resisting Night Cream Versus Advanced Clinicals Encapsulated Retinol Rapid Wrinkle Rewind Cream
This barrier-repair night moisturizer is formulated around Squalane and Panthenol to strengthen the skin barrier and hydrate skin.
This anti-aging night moisturizer is formulated around Retinol and Ferulic Acid to soften the look of wrinkles and refine skin texture.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningC12-15 Alkyl Benzoate
AntimicrobialBehenyl Behenate
EmollientGlycerin
HumectantSqualane
EmollientButylene Glycol
HumectantCetyl Palmitate
EmollientPolyhydroxystearic Acid
EmulsifyingPolyglyceryl-10 Stearate
Skin ConditioningPanthenol
Skin ConditioningDimethicone
EmollientPhenoxyethanol
PreservativeCarbomer
Emulsion StabilisingEuphorbia Cerifera Cera
AstringentSodium Stearoyl Lactylate
EmulsifyingTocopheryl Acetate
AntioxidantSodium Hydroxide
BufferingEthylhexylglycerin
Skin ConditioningPentylene Glycol
Skin ConditioningSerine
MaskingSodium Lactate
BufferingLactic Acid
BufferingUrea
BufferingFomes Officinalis Extract
Skin ProtectingSorbitol
HumectantPantolactone
HumectantPEG-40 Hydrogenated Castor Oil
EmulsifyingBisabolol
AntioxidantBorago Officinalis Seed Oil
EmollientSodium Chloride
MaskingPropylene Glycol
HumectantAllantoin
Skin ConditioningCamellia Sinensis Leaf Extract
AntimicrobialWater, C12-15 Alkyl Benzoate, Behenyl Behenate, Glycerin, Squalane, Butylene Glycol, Cetyl Palmitate, Polyhydroxystearic Acid, Polyglyceryl-10 Stearate, Panthenol, Dimethicone, Phenoxyethanol, Carbomer, Euphorbia Cerifera Cera, Sodium Stearoyl Lactylate, Tocopheryl Acetate, Sodium Hydroxide, Ethylhexylglycerin, Pentylene Glycol, Serine, Sodium Lactate, Lactic Acid, Urea, Fomes Officinalis Extract, Sorbitol, Pantolactone, PEG-40 Hydrogenated Castor Oil, Bisabolol, Borago Officinalis Seed Oil, Sodium Chloride, Propylene Glycol, Allantoin, Camellia Sinensis Leaf Extract
Water
Skin ConditioningCaprylic/Capric Triglyceride
MaskingDimethicone
EmollientGlyceryl Stearate
EmollientAmmonium Acryloyldimethyltaurate/Vp Copolymer
Cetearyl Phosphate
Skin ConditioningCetyl Alcohol
EmollientBehenyl Alcohol
EmollientGlycerin
HumectantRetinol
Skin ConditioningFerulic Acid
AntimicrobialPalmitoyl Tripeptide-37
Skin ConditioningPyrus Malus Fruit Extract
Skin ConditioningButyrospermum Parkii Butter
Skin ConditioningSclerocarya Birrea Seed Oil
HumectantRosa Canina Fruit Oil
EmollientOryza Sativa Bran Extract
Skin ConditioningRosmarinus Officinalis Leaf Extract
AntimicrobialHelianthus Annuus Extract
EmollientDimethicone Crosspolymer
Emulsion StabilisingCurcuma Longa Root Extract
AntioxidantCopernicia Cerifera Cera
EmollientPropanediol
SolventSodium Cocoamphoacetate
CleansingRosa Damascena Flower Water
MaskingPunica Granatum Fruit Extract
AntioxidantCamellia Sinensis Leaf Water
MaskingLavandula Angustifolia Oil
MaskingTocopheryl Acetate
AntioxidantSynthetic Beeswax
Emulsion StabilisingBHT
AntioxidantXanthan Gum
EmulsifyingBHA
AntioxidantSilica Dimethyl Silylate
EmollientPhenoxyethanol
PreservativeTocopherol
AntioxidantTetrasodium Glutamate Diacetate
Caprylyl Glycol
EmollientEthylhexylglycerin
Skin ConditioningHexylene Glycol
EmulsifyingSodium Hydroxide
BufferingLinalool
PerfumingWater, Caprylic/Capric Triglyceride, Dimethicone, Glyceryl Stearate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Cetearyl Phosphate, Cetyl Alcohol, Behenyl Alcohol, Glycerin, Retinol, Ferulic Acid, Palmitoyl Tripeptide-37, Pyrus Malus Fruit Extract, Butyrospermum Parkii Butter, Sclerocarya Birrea Seed Oil, Rosa Canina Fruit Oil, Oryza Sativa Bran Extract, Rosmarinus Officinalis Leaf Extract, Helianthus Annuus Extract, Dimethicone Crosspolymer, Curcuma Longa Root Extract, Copernicia Cerifera Cera, Propanediol, Sodium Cocoamphoacetate, Rosa Damascena Flower Water, Punica Granatum Fruit Extract, Camellia Sinensis Leaf Water, Lavandula Angustifolia Oil, Tocopheryl Acetate, Synthetic Beeswax, BHT, Xanthan Gum, BHA, Silica Dimethyl Silylate, Phenoxyethanol, Tocopherol, Tetrasodium Glutamate Diacetate, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Sodium Hydroxide, Linalool
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideTocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Learn more about Tocopheryl AcetateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water