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Paula's Choice Clear Oil-Free Moisturizer Versus Neutrogena Clear & Defend Oil-Free Moisturiser

General Moisturizer
General Moisturizer
American Brand United States
American Brand United States

Updated on July 17, 2024

Overview

What they are

These products are both general moisturizers. They have a total of 6 ingredients in common

Suited For

They're both likely to be good for fighting acne, dry skin, brightening skin, sensitive skin, oily skin, reducing pores and scar healing

Free From

They both do not contain any oils or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Notable Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Clear Oil-Free Moisturizer
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Ethyl Macadamiate Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Ethyl Macadamiate isn't fungal acne safe.

Disliked Full details ->
Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Cetearyl Alcohol Emollient, Emulsifying, Emulsion Stabilising
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon
Fatty AlcoholFatty Alcohol Icon 3 Concerns

Cetearyl alcohol is a mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is mainly used as an emulsifier. Emulsifiers help prevent the separation of oils and products. Due to its composition, it can also be used to thicken a product or help create foam.

2 Com. / 1 Irr.
Very Disliked Full details ->
Propanediol Solvent

Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.

Triethylhexanoin Masking, Skin Conditioning

Triethylhexanoin is created from glycerin and 2-ethylhexanoic acid. It is a solvent and emollient.

Sodium Acrylates Copolymer

We don't have a description for Sodium Acrylates Copolymer.

Very Disliked Full details ->
Glyceryl Stearate Emollient, Emulsifying
1 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Glyceryl Stearate is a mix of glycerin and stearic acid.

1 Com. / 0 Irr.
Disliked Full details ->
Peg-100 Stearate
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Peg-100 Stearate is an emollient and emulsifier. PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.

0 Com. / 0 Irr.
Very Disliked Full details ->
Glycyrrhiza Glabra Root Skin Conditioning

Glycyrrhiza Glabra Root is the roots of the Licorice, Glycyrrhiza glabra L., Leguminosae.

Hydrolyzed Pumpkin Seedcake Skin Protecting
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Hydrolyzed Pumpkin Seedcake isn't fungal acne safe.

Unknown Full details ->
Vaccinium Angustifolium Fruit Extract Skin Protecting, Soothing

We don't have a description for Vaccinium Angustifolium Fruit Extract.

Euterpe Oleracea Fruit Extract

This extract comes from the Cabbage Palm, AKA the Açaí berry! It has skin soothing, antioxidant, and anti-aging properties.

Prunus Serotina Fruit Extract Masking, Moisturising, Skin Conditioning

We don't have a description for Prunus Serotina Fruit Extract.

Unknown Full details ->
Niacinamide Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconGood for Minimizing Pores IconGood for Dark Spots IconHelps fight Acne IconHelps brighten skin Icon
NiacinamideNiacinamide Icon 6 Benefits

Niacinamide has emerged as an all-star ingredient due to its many benefits.

Tripeptide-29 Skin Conditioning
Peptide Icon
PeptidePeptide Icon

Tripeptide-29 is a peptide.

Ceramide NP Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon
CeramideCeramide Icon 4 Benefits

Ceramide NP is a type of ceramide.

Ceramide AP Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon
CeramideCeramide Icon 4 Benefits

Ceramide AP is a type of Ceramide.

Ceramide EOP Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon
CeramideCeramide Icon 4 Benefits

Ceramide EOP is a type of Ceramide.

Sodium Hyaluronate Humectant, Skin Conditioning
0 / 0 Hyaluronic Acid Icon
Hyaluronic AcidHyaluronic Acid Icon

Sodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.

0 Com. / 0 Irr.
Phytosphingosine Skin Conditioning

Phytosphingosine is a phospholipid naturally found in our skin. It helps moisturize, soothe, and protect skin.

Cholesterol Emollient, Emulsifying, Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness Icon
2 Benefits

Cholesterol is a class of organic molecules called lipids. It helps hydrate your skin and is essential to having a healthy skin barrier.

0 Com. / 0 Irr.
Panthenol Skin Conditioning
0 / 0 Helps reduce irritation Icon
Helps reduce irritationHelps reduce irritation Icon

Panthenol is a common ingredient that helps hydrate and soothe the skin. It can be found naturally in our skin and hair.

0 Com. / 0 Irr.
Sodium PCA Humectant, Skin Conditioning
0 / 0

Sodium PCA is the sodium salt of pyroglutamic acid and is naturally occurring on human skin.

0 Com. / 0 Irr.
Adenosine Skin Conditioning
Helps with Anti-Aging IconGood for Scar Healing Icon
2 Benefits

Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.

Lecithin Emollient, Emulsifying, Skin Conditioning

Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.

Disliked Full details ->
Arginine Masking, Skin Conditioning
Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Arginine is an amino acid that is important for human development. Your body uses is it to produce hair keratin and skin collagen.

Sodium Lauroyl Lactylate Emulsifying

Sodium Lauroyl Lactylate is the lauric acid sodium salt of lactyl lactate.

Sodium Gluconate Skin Conditioning

This is the synthetic salt of gluconic acid, a form of PHA and mild exfoliant.

Unknown Full details ->
Citric Acid Buffering, Masking
AHA IconGood for Skin Texture IconGood for Minimizing Pores IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation IconMay worsen Rosacea Icon
AHAAHA Icon 4 Benefits 2 Concerns

Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).

Disliked Full details ->
Isohexadecane Emollient, Skin Conditioning, Solvent

Isohexadecane is added to enhance texture, emulsify, and to help cleanse. It is an isoparrafin. It is a component of petrolatum.

Xanthan Gum Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

Disliked Full details ->
Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Ethylhexylglycerin Skin Conditioning

Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.

Clear & Defend Oil-Free Moisturiser
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Propylene Glycol Humectant, Skin Conditioning, Solvent
0 / 0 May worsen Eczema Icon
May worsen EczemaMay worsen Eczema Icon

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

0 Com. / 0 Irr.
Disliked Full details ->
Cetyl Alcohol Emollient, Emulsifying, Emulsion Stabilising
2 / 2 Fatty Alcohol Icon
Fatty AlcoholFatty Alcohol Icon

Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.

2 Com. / 2 Irr.
Very Disliked Full details ->
C12-15 Alkyl Benzoate Antimicrobial, Emollient, Skin Conditioning

C12-15 Alkyl Benzoate is made up of Benzoic Acid and long chain alcohols. It has a low molecular weight.

Disliked Full details ->
Stearyl Alcohol Emollient, Emulsifying, Emulsion Stabilising
2 / 2 Fatty Alcohol Icon
Fatty AlcoholFatty Alcohol Icon

Stearyl Alcohol is a type of fatty alcohol from stearic acid. It is a white, waxy compound used to emulsify ingredients.

2 Com. / 2 Irr.
Very Disliked Full details ->
Glyceryl Stearate Emollient, Emulsifying
1 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Glyceryl Stearate is a mix of glycerin and stearic acid.

1 Com. / 0 Irr.
Disliked Full details ->
Peg-100 Stearate
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Peg-100 Stearate is an emollient and emulsifier. PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.

0 Com. / 0 Irr.
Very Disliked Full details ->
C12-15 Alkyl Lactate Emollient, Skin Conditioning

We don't have a description for C12-15 Alkyl Lactate.

Unknown Full details ->
Aloe Barbadensis Leaf Extract Emollient, Humectant, Skin Conditioning

Aloe Barbadensis Leaf Extract is an extract of the leaves of the aloe, Aloe barbadensis, Liliaceae.

Chamomilla Recutita Extract Skin Conditioning
0 / 0 Helps reduce irritation Icon
Helps reduce irritationHelps reduce irritation Icon

Chamomilla Recutita Extract comes from the Chamomile flower.

0 Com. / 0 Irr.
Cetyl Lactate Emollient, Skin Conditioning

We don't have a description for Cetyl Lactate.

Unknown Full details ->
Cocamidopropyl Pg-Dimonium Chloride Phosphate

We don't have a description for Cocamidopropyl Pg-Dimonium Chloride Phosphate.

Unknown Full details ->
Salicylic Acid Masking, Preservative, Skin Conditioning
BHA IconPreservative IconGood for Oily Skin IconGood for Minimizing Pores IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconCan worsen Dry Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon
BHABHA Icon PreservativePreservative Icon 5 Benefits 4 Concerns

Salicylic Acid (also known as beta hydroxy acid or BHA) is one of the most well-known ingredients for treating skin that struggles with blackheads and acne. It helps to exfoliate both the skin's surface and pores, and also acts as an anti-inflammatory agent.

Menthyl Lactate Masking, Refreshing

We don't have a description for Menthyl Lactate.

Unknown Full details ->
Dimethicone Emollient, Skin Conditioning, Skin Protecting
1 / 0 Silicon Icon
SiliconSilicon Icon

Dimethicone is a silicone used for making products smooth and silky. It also has the added benefit of sealing in hydration. The amount of dimethicone found in beauty products is considered safe and non-comedogenic, meaning it won't clog pores.

1 Com. / 0 Irr.
Very Disliked Full details ->
Cyclohexasiloxane Emollient, Skin Conditioning, Solvent
Silicon Icon
SiliconSilicon Icon

Cyclohexasiloxane is a type of silicone more commonly known as D6. It is an emollient and solvent.

Disliked Full details ->
Cyclopentasiloxane Emollient, Skin Conditioning, Solvent
Silicon Icon
SiliconSilicon Icon

Cyclopentasiloxane is a silicone used to improve texture and trap moisture. An easier name for this is D5.

Disliked Full details ->
Sodium Isostearoyl Lactylate Emulsifying

We don't have a description for Sodium Isostearoyl Lactylate.

Unknown Full details ->
Propylene Glycol Isostearate Skin Conditioning
3-4 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

This ingredient is created by reacting propylene glycol with isostearic acid.

3-4 Com. / 0 Irr.
Unknown Full details ->
Palmitic Acid Emollient, Emulsifying
2 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon
2 Concerns

Palmitic Acid is a fatty acid found in our skin. In cosmetics, it is usually derived from palm oil. It is a cleanser, emollient, and emulsifier.

2 Com. / 0 Irr.
Very Disliked Full details ->
Stearic Acid Cleansing, Emulsifying, Emulsion Stabilising
2-3 / 0 May worsen Oily Skin IconNot safe for Fungal Acne Icon
2 Concerns

Stearic Acid is a fatty acid. It is an emollient, emulsifier, and texture enhancer.

2-3 Com. / 0 Irr.
Very Disliked Full details ->
Carbomer Emulsion Stabilising, Gel Forming
1 / 0

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

1 Com. / 0 Irr.
Disliked Full details ->
Acrylates/C10-30 Alkyl Acrylate Crosspolymer Emulsion Stabilising

Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken and improve the texture of products.

Disliked Full details ->
Sodium Chloride Masking
Can worsen Dry Skin IconBad for Acne Prone Skin IconMay worsen Rosacea Icon
3 Concerns

Chances are, you eat sodium chloride every day. Sodium Chloride is also known as table salt.

Very Disliked Full details ->
Disodium EDTA

Disodium EDTA plays a role in making products more stable by aiding other preservatives.

Disliked Full details ->
Sodium Hydroxide Buffering

Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.

Benzalkonium Chloride Antimicrobial, Preservative
Preservative IconMay cause irritation IconMay worsen Eczema Icon
PreservativePreservative Icon 2 Concerns

Benzalkonium Chloride is a preservative. It can cause irritation and worsen eczema.

Very Disliked Full details ->
Methylparaben Preservative
0 / 0 Preservative IconParaben IconNon-Reef-Safe IconMay worsen Eczema Icon
PreservativePreservative Icon ParabenParaben Icon 2 Concerns

Methylparaben is a preservative and is a paraben. It is used to prevent the growth of fungus, mold, and other harmful bacteria. Parabens are chemicals used as preservatives in both cosmetics and food.

0 Com. / 0 Irr.
Very Disliked Full details ->
Propylparaben Preservative
0 / 0 Preservative IconParaben IconCan worsen Dry Skin IconNon-Reef-Safe Icon
PreservativePreservative Icon ParabenParaben Icon 2 Concerns

Propylparaben is a preservative and is a paraben with antifungal and antimicrobial properties.

0 Com. / 0 Irr.
Very Disliked Full details ->
Ethylparaben Preservative
Preservative IconParaben IconNon-Reef-Safe Icon
PreservativePreservative Icon ParabenParaben Icon Non-Reef-SafeNon-Reef-Safe Icon

Ethylparaben is a preservative, is a paraben, and is not reef safe.

Very Disliked Full details ->
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Parfum Masking, Perfuming
Fragrance IconMay worsen Eczema IconMay worsen Rosacea Icon
FragranceFragrance Icon 2 Concerns

Parfum is a catch-all term for an ingredient or more that is used to give a scent to products.

Very Disliked Full details ->
Benzyl Alcohol Perfuming, Preservative, Solvent
Alcohol IconFragrance IconPreservative IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconEU Allergen IconMay worsen Eczema IconMay worsen Rosacea Icon
AlcoholAlcohol Icon FragranceFragrance Icon PreservativePreservative Icon 6 Concerns

Benzyl Alcohol is most commonly used as a preservative. It also has a subtle, sweet smell. Small amounts of Benzyl Alcohol is not irritating and safe to use in skincare products. Most Benzyl Alcohol is derived from fruits such as apricots.

Very Disliked Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emollient, Emulsifying
Disliked

Glyceryl Stearate is a mix of glycerin and stearic acid.

Glyceryl Stearate is used to stabilize the mixing of water and oil ingredients. By preventing these ingredients from separating, it can help elongate shelf life. It can also help thicken the product's texture.

As an emollient, it helps soften skin and supports barrier-replenishing ingredients.

In cosmetics, Glyceryl Stearate is often made from vegetable oils or synthetically produced. The human body also creates Glyceryl Stearate naturally.

Learn more about Glyceryl Stearate
Very Disliked

Peg-100 Stearate is an emollient and emulsifier. PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.

Peg-100 Stearate helps keep skin soft by trapping moisture in. It helps prevent oil and water from separating in a product. By binding oil and water, it helps remove dirt and oil to be rinsed away.

Emulsion Stabilising, Gel Forming
Disliked

Carbomer is a polymer of acrylic acid. Its main role is to create gel consistency within products.

Carbomer is commonly found in many types of cosmetics products. It is found to be safe in concentrations up to 15%. However, a high amount of carbomer can cause pilling or balling up of products. Most products contain 1% of less of carbomer.

Preservative
Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Ingredient Ratings

Here's what our community thinks of the ingredients in these products.

Clear Oil-Free Moisturizer
18
4
10
3
liked
mixed
disliked
not rated
Clear & Defend Oil-Free Moisturiser
5
1
22
6
liked
mixed
disliked
not rated

When to use

109 Routines
42% use in am
58% use in pm
95% use every day
When to use See routines that use it ->
18 Routines
50% use in am
50% use in pm
94% use every day

Reviews

Here's what our community thinks

Paula's Choice Clear Oil-Free Moisturizer 35 ingredients

2.5 /5
from 2 ratings
Doesn't Work (1) Oily (1) Sticky (1)

Neutrogena Clear & Defend Oil-Free Moisturiser 34 ingredients

3.0 /5
from 1 rating
Expensive (1)
Hubayobi's avatar

Hubayobi

5 months ago · Combination Skin
Review

Simple moisturizer. There’s better ones out there