Versus

Necessaire The Neck Serum Versus DRMTLGY Advanced Neck Cream

Serum
General Moisturizer
American Brand United States
American Brand United States

Updated on February 18, 2025

Overview

What they are

These products are both reef safe . They have a total of 6 ingredients in common

Cool Features

They both contain peptides and Vitamin E

Suited For

They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, scar healing and dark spots

Free From

They both do not contain any harsh alcohols, parabens or sulfates

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

Necessaire The Neck Serum 33 ingredients

DRMTLGY Advanced Neck Cream 49 ingredients

What's inside

What's inside

At a glance

Click on any of the items below to learn more

Necessaire The Neck Serum 33 ingredients

DRMTLGY Advanced Neck Cream 49 ingredients

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
The Neck Serum
Advanced Neck Cream

Water

Skin Conditioning

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Isopropyl Palmitate

Emollient
3-4 / 1 May worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

C12-15 Alkyl Benzoate

Antimicrobial

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Dimethicone

Emollient
1 / 0 Silicon Icon

Isododecane

Emollient

Cetyl Alcohol

Emollient
2 / 2 Fatty Alcohol Icon

Cetearyl Alcohol

Emollient
2 / 1 Fatty Alcohol IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Butyrospermum Parkii Butter

Skin Conditioning
Helps hydrate Dry Skin IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Pyrus Malus Fruit Extract

Skin Conditioning
Helps hydrate Dry Skin Icon

PEG-100 Stearate

0 / 0 Not safe for Fungal Acne Icon

Glycol Distearate

Emollient
Not safe for Fungal Acne Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Triticum Vulgare Germ Oil

Emollient
Oil IconMay worsen Oily Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Prunus Amygdalus Dulcis Oil

Skin Conditioning
3 / 0 Oil IconHelps hydrate Dry Skin IconBad for Acne Prone Skin IconNot safe for Fungal Acne Icon

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide AP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Ceramide EOP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Phytosphingosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

Sodium Lauroyl Lactylate

Emulsifying

Xanthan Gum

Emulsifying

Palmitoyl Tripeptide-5

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Phenoxyethanol

Preservative
Preservative Icon

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant Icon

Pentylene Glycol

Skin Conditioning

Prunus Amygdalus Dulcis Seed Extract

Skin Conditioning

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Emulsion Stabilising

Dimethicone/Vinyl Dimethicone Crosspolymer

Skin Conditioning
Silicon Icon

Sodium Polystyrene Sulfonate

Emulsion Stabilising

Sorghum Bicolor Stalk Juice

Skin Conditioning

Ethylhexylglycerin

Skin Conditioning

Secale Cereale Seed Extract

Abrasive
Exfoliant Icon

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Sorbitan Laurate

Emulsifying
1-2 / 1-2 Not safe for Fungal Acne Icon

Trifluoroacetyl Tripeptide-2

Skin Conditioning
Peptide Icon

Palmitoyl Tripeptide-1

Skin Conditioning
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Palmitoyl Tetrapeptide-7

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Polysorbate 20

Emulsifying
0 / 0 Not safe for Fungal Acne Icon

Sodium Hydroxide

Buffering

3-Aminopropane Sulfonic Acid

Calcium Hydroxymethionine

Skin Conditioning

Disodium EDTA

Hydroxyethylcellulose

Emulsion Stabilising

Nelumbo Nucifera Leaf Extract

Skin Conditioning

Acetyl Dipeptide-1 Cetyl Ester

Skin Conditioning
Peptide IconHelps reduce irritation IconHelps with Anti-Aging IconGood for Dark Spots Icon

Carbomer

Emulsion Stabilising
1 / 0

Dextran

Helps hydrate Dry Skin Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Humectant, Skin Conditioning, Skin Protecting

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Skin Conditioning

Palmitoyl Tetrapeptide-7 is a lab-made peptide with anti-inflammatory and skin-repairing benefits. It's made up of four amino acids (glycine, glutamine, proline, and arginine) and palmitic acid (which helps it penetrate skin more effectively).

This ingredient helps reduce inflammation by limiting the production of interleukin-6 (IL-6), a chemical that triggers inflammatory responses, particularly after UV exposure.

Less inflammation = slower collagen breakdown and a longer-lasting, youthful appearance.

Palmitoyl Tetrapeptide-7 also stimulates collagen production and supports a healthier skin barrier.

Over time, this can improve skin firmness, hydration, and reduce the appearance of fine lines. It’s commonly paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.

This ingredient has been shown to be effective and safe in cosmetic use and you'll typically find it in small amounts (less than 0.01%).

Due to its palmitic acid base, it may not be safe for Malassezia folliculitis.

Read more about other common types of peptides here:

Learn more about Palmitoyl Tetrapeptide-7
Skin Conditioning

Palmitoyl Tripeptide-1 is also known as pal-GHK. It is made up of 3 amino acids and palmitic acid, a fatty acid that helps it absorb into skin more easily.

This peptide is as a signal peptide, meaning it tells the skin to produce more collagen. Collagen is the key protein that helps form the skin's structure and keep it plump, firm, and hydrated.

By boosting collagen production, this ingredient supports a stronger skin barrier and helps reduce the appearance of wrinkles.

You'll most likely see this ingredient paired with Palmitoyl Tetrapeptide-7 in the well-known Matrixyl 3000 complex. While results from in-house testing should be viewed cautiously, this peptide duo is among the most studied and widely used in modern skincare.

Due to its palmitic acid base, this ingredient may not be safe for Malassezia folliculitis.

Read more about other common types of peptides here:

Learn more about Palmitoyl Tripeptide-1
Skin Conditioning

This synthetic peptide is created from lysine, valine, and palmitic acid.

According to the manufacturer, in-vitro studies show tissue growth and collagen synthesis. Another in-vivo study found 60 volunteers saw a significant reduction in wrinkles after 84 days.

Due to its palmitic acid base, this peptide may not be fungal-acne safe.

Learn more about Palmitoyl Tripeptide-5
Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Emulsifying, Emulsion Stabilising, Gel Forming

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

Learn more about Xanthan Gum

When to use

Necessaire The Neck Serum 33 ingredients

DRMTLGY Advanced Neck Cream 49 ingredients

12 Routines
42% use in am
67% use in pm
92% use every day
6 Routines
33% use in am
67% use in pm
100% use every day

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Necessaire The Neck Serum 33 ingredients

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Overall rating
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1
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Strong Scent 100%

DRMTLGY Advanced Neck Cream 49 ingredients

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