Medik8 Crystal Retinal 10 Versus Obagi Retinol 1.0
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningCaprylic/Capric Triglyceride
MaskingGlycerin
HumectantIsododecane
EmollientCetearyl Olivate
Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingCetearyl Alcohol
EmollientPPG-12/Smdi Copolymer
EmollientSorbitan Olivate
EmulsifyingTocopheryl Acetate
AntioxidantTitanium Dioxide
Cosmetic ColorantEclipta Prostrata Extract
Skin ConditioningCyclodextrin
AbsorbentSqualane
EmollientHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingPhenoxyethanol
PreservativeMelia Azadirachta Leaf Extract
Skin ConditioningHydroxypropyl Methylcellulose
Emulsion StabilisingSodium Hyaluronate
HumectantTetrahexyldecyl Ascorbate
AntioxidantRubus Chamaemorus Seed Oil
Skin ConditioningAlumina
AbrasiveIsostearic Acid
CleansingLecithin
EmollientPolyglyceryl-3 Polyricinoleate
EmulsifyingPolyhydroxystearic Acid
EmulsifyingStearic Acid
CleansingPentylene Glycol
Skin ConditioningRetinal
Skin ConditioningMoringa Oleifera Seed Oil
EmollientSodium Polyaspartate
HumectantClimbazole
AntimicrobialDisodium EDTA
Lonicera Japonica Flower Extract
Skin ConditioningLonicera Caprifolium Flower Extract
PerfumingDaucus Carota Sativa Seed Oil
EmollientEthylhexylglycerin
Skin Conditioning3-O-Ethyl Ascorbic Acid
Skin ConditioningDipteryx Odorata Bean Extract
MaskingHydroxyacetophenone
AntioxidantPolysorbate 60
EmulsifyingSorbitan Isostearate
EmulsifyingVanilla Planifolia Fruit Extract
Skin ConditioningDecylene Glycol
Skin Conditioning1,2-Hexanediol
Skin ConditioningBHT
AntioxidantCoumarin
PerfumingWater, Caprylic/Capric Triglyceride, Glycerin, Isododecane, Cetearyl Olivate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, PPG-12/Smdi Copolymer, Sorbitan Olivate, Tocopheryl Acetate, Titanium Dioxide, Eclipta Prostrata Extract, Cyclodextrin, Squalane, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Phenoxyethanol, Melia Azadirachta Leaf Extract, Hydroxypropyl Methylcellulose, Sodium Hyaluronate, Tetrahexyldecyl Ascorbate, Rubus Chamaemorus Seed Oil, Alumina, Isostearic Acid, Lecithin, Polyglyceryl-3 Polyricinoleate, Polyhydroxystearic Acid, Stearic Acid, Pentylene Glycol, Retinal, Moringa Oleifera Seed Oil, Sodium Polyaspartate, Climbazole, Disodium EDTA, Lonicera Japonica Flower Extract, Lonicera Caprifolium Flower Extract, Daucus Carota Sativa Seed Oil, Ethylhexylglycerin, 3-O-Ethyl Ascorbic Acid, Dipteryx Odorata Bean Extract, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Vanilla Planifolia Fruit Extract, Decylene Glycol, 1,2-Hexanediol, BHT, Coumarin
Water
Skin ConditioningCaprylic/Capric Triglyceride
MaskingGlyceryl Stearate
EmollientCyclopentasiloxane
EmollientButylene Glycol
HumectantStearic Acid
CleansingButyrospermum Parkii Butter
Skin ConditioningPolysorbate 60
EmulsifyingStearyl Alcohol
EmollientGlycerin
HumectantAllyl Methacrylates Crosspolymer
Emulsion StabilisingRetinol
Skin ConditioningPolysorbate 20
EmulsifyingDimethicone
EmollientSimmondsia Chinensis Seed Oil
EmollientChamomilla Recutita Flower Extract
MaskingHypericum Perforatum Flower Extract
Skin ConditioningMalva Sylvestris Flower Extract
Skin ConditioningSalvia Officinalis Leaf Extract
CleansingSambucus Nigra Flower Extract
RefreshingCyclohexasiloxane
EmollientSorbitol
HumectantTocopheryl Acetate
AntioxidantAscorbic Acid
AntioxidantUbiquinone
AntioxidantSodium Hyaluronate
HumectantPropylene Glycol
HumectantBHT
AntioxidantBisabolol
AntioxidantDimethicone/Vinyl Dimethicone Crosspolymer
Skin ConditioningDipotassium Glycyrrhizate
HumectantDisodium EDTA
Triethanolamine
BufferingCarbomer
Emulsion StabilisingGlyceryl Acrylate/Acrylic Acid Copolymer
HumectantCaprylyl Glycol
EmollientEthylhexylglycerin
Skin ConditioningHexylene Glycol
EmulsifyingPhenoxyethanol
PreservativeWater, Caprylic/Capric Triglyceride, Glyceryl Stearate, Cyclopentasiloxane, Butylene Glycol, Stearic Acid, Butyrospermum Parkii Butter, Polysorbate 60, Stearyl Alcohol, Glycerin, Allyl Methacrylates Crosspolymer, Retinol, Polysorbate 20, Dimethicone, Simmondsia Chinensis Seed Oil, Chamomilla Recutita Flower Extract, Hypericum Perforatum Flower Extract, Malva Sylvestris Flower Extract, Salvia Officinalis Leaf Extract, Sambucus Nigra Flower Extract, Cyclohexasiloxane, Sorbitol, Tocopheryl Acetate, Ascorbic Acid, Ubiquinone, Sodium Hyaluronate, Propylene Glycol, BHT, Bisabolol, Dimethicone/Vinyl Dimethicone Crosspolymer, Dipotassium Glycyrrhizate, Disodium EDTA, Triethanolamine, Carbomer, Glyceryl Acrylate/Acrylic Acid Copolymer, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Phenoxyethanol
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
BHT is a synthetic antioxidant and preservative.
As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.
As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.
The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.
However, it was recently restricted for use in the UK as of April 2024.
Learn more about BHTCaprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideDisodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Polysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.
Polysorbate 60 is sorbitol-based and created from the ethoxylation of sorbitan. Ethoxylation is a chemical reaction used to add ethylene oxide. Sorbitan is a the dehydrated version of sorbitol, a sugar found in fruits.
In this case, the 60 comes from reacting 60 units of ethylene oxide with sorbitan.
Polysorbates are commonly used in medicine and foods.
Learn more about Polysorbate 60Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateStearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.
In cosmetics, it is a multitasker:
Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.
Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.
Learn more about Stearic AcidTocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.
Tocopheryl Acetate is commonly found in both skincare and dietary supplements.
Learn more about Tocopheryl AcetateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water