Overview
What they are
These products are both vegan and reef safe serums. They have a total of 5 ingredients in common
Cool Features
They both contain retinoid and Vitamin E
Suited For
They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any common allergens, oils, parabens or silicones
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Is Clinical Pro-Heal Serum Advance 17 ingredients
Shani Darden Retinol Reform 43 ingredients
At a glance
Click on any of the items below to learn more
Is Clinical Pro-Heal Serum Advance 17 ingredients
Shani Darden Retinol Reform 43 ingredients
Notable Ingredients
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This product contains 1 ingredient that may have this attribute:
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Concerns
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Ingredients Side-by-side
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Antioxidant 6 Benefits
Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.
Laureth-4 is created by reacting ethylene oxide with Lauryl Alcohol. It is a surfactant and emulsifier.
5 Concerns
Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.
Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.
Triethanolamine is an emulsifier and pH adjuster. It is created using ethylene oxide and ammonia. This gives Triethanolamine a nitrogen core and a similar scent to ammonia.
Antioxidant 4 Benefits May cause irritation
Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Bioflavonoids are secondary metabolites found in plants. They contain antioxidants.
8 Benefits 3 Concerns
Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
2 Benefits
Arbutin is derived from the bearberry plant. It helps even out skin tone and reduce hyperpigmentation.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
Caprylic/Capric Triglyceride is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
Pyrus Malus Fruit Extract is extract from Apples. Apples are rich in Vitamin C, sugars, and antioxidants.
6 Benefits 3 Concerns
Lactic Acid is an AHA that is derived from fermenting lactose, a carbohydrate from milk. It removes the top layer of old and dead skin cells and helps increase cell turnover.
This is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.
Lactobacillus Ferment is created by fermenting the Lactobacillus bacteria. It helps keep our skin's natural barrier and microbiome healthy.
Isohexadecane is added to enhance texture, emulsify, and to help cleanse. It is an isoparrafin. It is a component of petrolatum.
8 Benefits 3 Concerns
Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
Copernicia Cerifera Wax comes from a palm tree native to Brazil. This wax is added to help give a thicker texture. It also helps create a film when applied.
5 Benefits
Camellia Sinensis Leaf Extract is derived from the leaves of the tea plant. Black tea, green tea, and oolong tea are all harvested from this plant.
Aloe Barbadensis Leaf Juice comes from leaves of the aloe plant. Aloe Barbadensis Leaf Juice is best known for helping to soothe sunburns. It is also anti-inflammatory, moisturizing, antiseptic, and can help heal wounds.
Antioxidant Helps brighten skin
Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.
6 Benefits
Niacinamide has emerged as an all-star ingredient due to its many benefits.
Hydrogenated Lecithin is created from the hydrogenation of lecithin. Hydrogenation is a chemical reaction between molecule hydrogen and another element.
3 Concerns
Linoleic Acid is Vitamin F and a fatty acid. It is an emollient and helps thicken texture. Linoleic acid helps with hydrating skin and nourishing the skin's barrier. The top layer of skin, or epidermis, contains high amounts of linoleic acid naturally.
Glycine Soja Sterols is derived from the soybean plant. Sterols are an organic compound and technically an alcohol.
Phospholipids are naturally found in our skin as they are the main component of cell membranes. Phospholipids have humectant, emollient, antioxidant properties.
Propanediol helps absorb ingredients into your skin, boosting their benefits. It can act as an emollient, making your skin softer. Propanediol can help products last longer by boosting the properties of preservatives within the formulation.
Sorbitan Isostearate is an emulsifer and cleaning agent. It is created from isostearic acid and sorbitol.
Polysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.
Oryza Sativa Bran Extract comes from the outer layer of a rice kernel. It is a byproduct of milling rice, or the operation to produce a whole grain rice product.
Rosmarinus Officinalis Leaf Extract comes from rosemary. Rosemary is native to the Mediterranean.
Antioxidant 4 Benefits May cause irritation
Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Guar gum is made from the guar bean, a plant native to India. It is considered a form of polysaccharide and naturally contains sugar.
Maltodextrin is a polysaccharide. It is derived from starch such as rice, corn, wheat, or potato starch.
Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
Lecithin is a term for a group of substances found in plants, animals, and humans. They are made up of mixture of fatty acids. These fatty acids usually are a mixture of phosphoric acid's choline ester connected to stearic, oleic, and palmitic acids. Most lecithins are created from plant ingredients scuh as sunflower.
This ingredient is created from dehydrating xylitol in acidic conditions. Xylitol is a famous sugar and humectant.
Tetrasodium Glutamate Diacetate is a chelating agent. Chelating agents help prevent metal ions from binding to other ingredients. This helps prevent unwanted effects and reactions from a product. These metal ions may come from water and are found in miniscule amounts.
This BHA stands for butylated hydroxyanisole. If you are looking for the beta-hydroxy acid, aka as Salicylic Acid, click here.
Sodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
Caprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
Hexylene Glycol is a surfactant. Glycols are a class of alcohols. Hexylene Glycol is a surfactant and emulsifier.
Water, Caprylic/Capric Triglyceride, Glycerin, Pyrus Malus Fruit Extract, Lactic Acid, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Lactobacillus Ferment, Isohexadecane, Retinol, Copernicia Cerifera Wax, Glucosamine Hcl, Plankton Extract, Camellia Sinensis Leaf Extract, Aloe Barbadensis Leaf Juice, Tocopheryl Acetate, Niacinamide, Hydrogenated Lecithin, Linoleic Acid, Glycine Soja Sterols, Phospholipids, Propanediol, Sodium Cocoamphoacetate, Sorbitan Isostearate, Polysorbate 60, Oryza Sativa Bran Extract, Rosmarinus Officinalis Leaf Extract, Helianthus Annuus Extract, Tocopherol, Cyamopsis Tetragonoloba Gum, Maltodextrin, Xanthan Gum, Lecithin, Hydrolyzed Algin, Xylitylglucoside, Anhydroxylitol, Xylitol, Tetrasodium Glutamate Diacetate, BHA, Sodium Hydroxide, Phenoxyethanol, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterTocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.
Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.
Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.
You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.
There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.
Learn more about TocopherolGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinRetinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.
Why is retinol famous?
It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.
Retinol is proven to:
This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.
Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).
Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
We recommend speaking with a medical professional about using this ingredient during pregnancy.
Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.
Read about Tretinoin
Learn more about RetinolPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Ingredient Ratings
Here's what our community thinks of the ingredients in these two products.
When to use
Is Clinical Pro-Heal Serum Advance 17 ingredients
Shani Darden Retinol Reform 43 ingredients
Reviews
Here's what our community thinks
Is Clinical Pro-Heal Serum Advance 17 ingredients
Shani Darden Retinol Reform 43 ingredients
screamadelica
the ingredients are fantastic. if you’re willing to splurge on a quality retinol serum, this one would be a great choice.
however, the smell is...
the ingredients are fantastic. if you’re willing to splurge on a quality retinol serum, this one would be a great choice.
however, the smell is horrible. if you can get past the smell, though, this would probably be a great option for sensitive skin as it doesn’t have any added fragrance.
