Is Clinical Pro-Heal Serum Advance Ingredients Explained

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Published on January 19, 2022 Submitted by dhochuli

Overview

What it is

Serum with 17 ingredients that contains retinoid, Vitamin C and Vitamin E

Cool Features

It is vegan and reef safe

Suited For

It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

It doesn't contain any common allergens, oils, parabens or silicones

Fun facts

Is Clinical is from United States. This product is used in 23 routines created by our community.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

You should know

Here's our breakdown of the notable ingredients, benefits, and concerns we determined from the ingredients in this product. Click any item to learn more.

Notable Ingredients

Retinoid
Vitamin C
Vitamin E

Benefits

Hydrating (2)
Good For Oily Skin
Redness Reducing
Skin Texture (2)
Reduces Large Pores
Anti-Aging (3)
Dark Spots (3)
Scar Healing (4)
Acne Fighting
Brightening (4)

Concerns

Drying (2)
May Worsen Oily Skin (2)
Irritating (3)
Rosacea
Eczema (3)

Ingredient Info

Click any item below to learn more and view relevant ingredients.
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free

Ingredients Overview

Here's our quick-to-read summary of the ingredients in this product. Keep scrolling if you'd like to learn more about what each ingredient does!
Ingredient
Features
1
Skin Conditioning, Solvent
2
Antioxidant, Buffering, Masking, Skin Conditioning
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon
3
Emulsifying, Masking
5 / 4
May worsen Oily Skin Icon
4
Antimicrobial, Astringent, Masking, Solvent
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon
5
Skin Conditioning, Solvent
6
Humectant, Skin Conditioning, Solvent
0 / 0
May worsen Eczema Icon
7
Buffering, Emulsifying, Masking
2 / 0
8
Antioxidant, Masking, Skin Conditioning
0-3 / 0-3
Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconMay cause irritation IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin Icon
9
Humectant, Skin Conditioning, Skin Protecting, Solvent
0 / 0
Helps hydrate Dry Skin IconHelps brighten skin Icon
10
Skin Conditioning, Soothing
11
Skin Conditioning
Retinoid IconCan worsen Dry Skin IconGood for Oily Skin IconMay cause irritation IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconMay worsen Eczema IconHelps brighten skin Icon
12
Perfuming, Skin Conditioning
Fragrance Icon
13
Antimicrobial, Astringent
Sulfate Icon
14
Skin Protecting
15
Antioxidant, Bleaching, Skin Conditioning
Antioxidant IconGood for Dark Spots IconGood for Scar Healing Icon
16
Emulsifying
0 / 0
Not safe for Fungal Acne Icon
17
Preservative
Preservative Icon

Ingredients Explained

This product contains 17 ingredients. Click on any ingredient to learn more about it
1
What it does: Skin Conditioning, Solvent
Community Rating: Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
2
What it does: Antioxidant, Buffering, Masking, Skin Conditioning
Community Rating: Loved

Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.

Not only is vitamin C great for your overall health and immune system, it also has plenty of benefits on your skin.

Vitamin C is best used for brightening skin. It improves dark spots, acne scars, and hyperpigmentation. This is because it blocks the process of skin darkening when exposed to UV.

Remember: Vitamin C should not replace sunscreen!

Your skin uses vitamin C to build collagen. Collagen is one key component in having a strong skin barrier and plump skin. Vitamin C also plays a role in regulating collagen, thus making it effective in improving wrinkles and fine lines.

Ascorbic acid shows potent antioxidant activity. As an antioxidant, it helps fight free-radicals. Free-radicals are molecules that may damage your skin cells. These antioxidants also protect skin against UV damage.

The best formulations include Vitamin E and/or ferulic acid. These two ingredients help stabilize and provide a boost in the benefits of ascorbic acid. This is because ascorbic acid becomes unstable when exposed to UV and air. In fact, you can tell your ascorbic acid has oxidized when it turns an orange-yellow color.

Ascorbic acid is generally compatible with other ingredients. However, using ascorbic acid with other active ingredients might cause irritation. Two ingredients: copper ions and benzoyl peroxide, will inactivate ascorbic acid completely.

Read more about other types of Vitamin C:

Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.

Learn more about Ascorbic Acid
3
What it does: Emulsifying, Masking

Laureth-4 is created by reacting ethylene oxide with Lauryl Alcohol. It is a surfactant and emulsifier.

Surfactants reduce the surface tension of ingredients so they can mix better. Emulsifiers prevent ingredients such as oil and water from separating.

4
What it does: Antimicrobial, Astringent, Masking, Solvent
Community Rating: Very Disliked

Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol and other additives. It has a low molecular weight and will evaporate quickly. This helps other ingredients become better absorbed and dry once applied.

Alcohol Denat. is volatile and may cause irritation. It helps draw out natural oils in skin and dry out your skin.

One study from 2005 found adding emollients to propanol-based sanitizer decreased irritation.

Alcohol is antibacterial by nature. This can help preserve products and increase their shelf life.

Other types of astringent alcohols include:

Learn more about Alcohol Denat.
5
What it does: Skin Conditioning, Solvent
Community Rating: Mixed

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.

This property also makes Pentylene Glycol a great texture enhancer. It can help thicken or emulsify a product. Emulsifiers help stabilize a product. It does this by preventing certain ingredients from separating.

Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.

Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.

Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.

Learn more about Pentylene Glycol
6
What it does: Humectant, Skin Conditioning, Solvent
Community Rating: Disliked

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.

This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.

Those with sensitive skin or conditions may deliver a rash when using this ingredient.

Learn more about Propylene Glycol
7
What it does: Buffering, Emulsifying, Masking
Community Rating: Very Disliked

Triethanolamine is an emulsifier and pH adjuster. It is created using ethylene oxide and ammonia. This gives Triethanolamine a nitrogen core and a similar scent to ammonia.

As an emulsifier, it prevents ingredients from separating and enhances texture by adding volume to a product.

PH adjusters are common in cosmetic products. The pH of a product can affect the effectiveness of other ingredients. A product with a high pH may also irritate the skin.

Learn more about Triethanolamine
8
What it does: Antioxidant, Masking, Skin Conditioning
Community Rating: Liked

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol
9
What it does: Humectant, Skin Conditioning, Skin Protecting, Solvent
Community Rating: Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
10
What it does: Skin Conditioning, Soothing
Community Rating: Liked

Bioflavonoids are secondary metabolites found in plants. They contain antioxidants.

Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

Foods containing high amounts of bioflavonoids include celery, peppers, berries, grapes, citrus fruits, cocoa, and more.

Learn more about Bioflavonoids
11
What it does: Skin Conditioning
Community Rating: Loved

Retinol is a form of Vitamin A and proven to help with anti-aging.

It promotes collagen production, increases new cell turnoever, and protects your skin as an antioxidant.

Retinol boosts collagen production and increases cell turnover. This makes retinol effective in removing wrinkles, fading dark spots, and reducing the appearance of pores.

Retinol is less effective when exposed to sun. Be sure to look for appropriate packaging to keep your retinol potent.

Using retinol and retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

We recommend speaking with a medical professional about using this ingredient during pregnancy.

Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.

Read about Tretinoin

Learn more about Retinol
12
What it does: Perfuming, Skin Conditioning

Olea Europaea Leaf Extract is a fragrance.

13
What it does: Antimicrobial, Astringent
Community Rating: Very Disliked

Zinc Sulfate is a type of sulfate.

14
What it does: Skin Protecting

We don't have a description for Polyporus Umbellatus Extract.

15
What it does: Antioxidant, Bleaching, Skin Conditioning
Community Rating: Loved

Arbutin is derived from the bearberry plant. It helps even out skin tone and reduce hyperpigmentation.

Arbutin blocks tyrosinase, an enzyme that starts the process of skin darkening. When applied to the skin, Arbutin works at a slow pace. This can make it less irritating than similar ingredients.

Arbutin has similar benefits to Kojic Acid

Learn more about Arbutin
16
What it does: Emulsifying
Community Rating: Very Disliked

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.

Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.

The lauric acid used to create Polysorbate 20 is often derived from coconuts.

Polysorbate 20 may not be fungal acne safe.

Learn more about Polysorbate 20
17
What it does: Preservative
Community Rating: Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Embed Ingredients

Here's what our community thinks of the 17 ingredients in this product ✨

41% are loved or liked
6% have mixed ratings
35% are disliked or very disliked
18% have no rating yet

When to use

Here's some more info on how this product is used by our community.

When to use

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