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Overview

What they are

These products are both vegan and reef safe serums. They have a total of 7 ingredients in common

Suited For

They're both likely to be good for dry skin, brightening skin, oily skin, scar healing and dark spots

Free From

They both do not contain any oils, parabens or silicones

What's Inside

They both contain harsh alcohols

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Is Clinical Pro-Heal Serum Advance
Is Clinical Active Serum
Is Clinical Active Serum
Serum
American Brand United States

Ingredient Info

Click any item below to learn more and see relevant ingredients

At a glance

Click on any of the items below to learn more

Notable Ingredients

Benefits

Concerns

Benefits

Concerns

Ingredients Side-by-side

found in both products
Pro-Heal Serum Advance
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Ascorbic Acid Antioxidant, Buffering, Masking
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon
Vitamin CVitamin C Icon AntioxidantAntioxidant Icon 6 Benefits

Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.

Laureth-4 Emulsifying, Masking
5 / 4 May worsen Oily Skin Icon
May worsen Oily SkinMay worsen Oily Skin Icon

Laureth-4 is created by reacting ethylene oxide with Lauryl Alcohol. It is a surfactant and emulsifier.

5 Com. / 4 Irr.
Unknown Full details ->
Alcohol Denat. Antimicrobial, Astringent, Masking
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon
AlcoholAlcohol Icon 5 Concerns

Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.

Very Disliked Full details ->
Pentylene Glycol Skin Conditioning, Solvent

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

Propylene Glycol Humectant, Skin Conditioning, Solvent
0 / 0 May worsen Eczema Icon
May worsen EczemaMay worsen Eczema Icon

Propylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.

0 Com. / 0 Irr.
Disliked Full details ->
Triethanolamine Buffering, Emulsifying, Masking
2 / 0

Triethanolamine is an emulsifier and pH adjuster. It is created using ethylene oxide and ammonia. This gives Triethanolamine a nitrogen core and a similar scent to ammonia.

2 Com. / 0 Irr.
Very Disliked Full details ->
Tocopherol Antioxidant, Masking, Skin Conditioning
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing IconHelps brighten skin IconMay cause irritation Icon
Vitamin EVitamin E Icon AntioxidantAntioxidant Icon 4 Benefits May cause irritationMay cause irritation Icon

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

0-3 Com. / 0-3 Irr.
Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Bioflavonoids Skin Conditioning, Soothing

Bioflavonoids are secondary metabolites found in plants. They contain antioxidants.

Retinol Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconCan worsen Dry Skin IconMay cause irritation IconMay worsen Eczema Icon
RetinoidRetinoid Icon 8 Benefits 3 Concerns

Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.

Olea Europaea Leaf Extract Perfuming, Skin Conditioning
Fragrance Icon
FragranceFragrance Icon

Olea Europaea Leaf Extract is a fragrance.

Zinc Sulfate Antimicrobial, Astringent
Sulfate Icon
SulfateSulfate Icon

Zinc Sulfate is a type of sulfate.

Disliked Full details ->
Polyporus Umbellatus Extract Skin Protecting

We don't have a description for Polyporus Umbellatus Extract.

Unknown Full details ->
Arbutin Antioxidant, Bleaching, Skin Conditioning
Antioxidant IconGood for Dark Spots IconGood for Scar Healing Icon
AntioxidantAntioxidant Icon 2 Benefits

Arbutin is derived from the bearberry plant. It helps even out skin tone and reduce hyperpigmentation.

Polysorbate 20 Emulsifying
0 / 0 Not safe for Fungal Acne Icon
Not safe for Fungal AcneNot safe for Fungal Acne Icon

Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.

0 Com. / 0 Irr.
Very Disliked Full details ->
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->
Active Serum
Water Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

Glycerin Humectant, Skin Conditioning, Skin Protecting
0 / 0 Helps hydrate Dry Skin IconHelps brighten skin Icon
2 Benefits

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

0 Com. / 0 Irr.
Butylene Glycol Humectant, Masking, Skin Conditioning
1 / 0

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

1 Com. / 0 Irr.
Alcohol Denat. Antimicrobial, Astringent, Masking
Alcohol IconCan worsen Dry Skin IconMay worsen Oily Skin IconMay cause irritation IconMay worsen Eczema IconMay worsen Rosacea Icon
AlcoholAlcohol Icon 5 Concerns

Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.

Very Disliked Full details ->
Saccharum Officinarum Extract Moisturising, Skin Conditioning

This ingredient is also called sugarcane extract. It is a moisturizing humectant and has skin soothing properties.

Vaccinium Myrtillus Fruit/Leaf Extract Astringent, Refreshing, Skin Conditioning

We don't have a description for Vaccinium Myrtillus Fruit/Leaf Extract.

Unknown Full details ->
Triethanolamine Buffering, Emulsifying, Masking
2 / 0

Triethanolamine is an emulsifier and pH adjuster. It is created using ethylene oxide and ammonia. This gives Triethanolamine a nitrogen core and a similar scent to ammonia.

2 Com. / 0 Irr.
Very Disliked Full details ->
Salix Alba Bark Extract Astringent, Skin Conditioning, Soothing
Good for Oily Skin Icon
Good for Oily SkinGood for Oily Skin Icon

Salix Alba Bark Extract comes from the white willow tree, which is native to Europe and Central Asia.

Glyceryl Polyacrylate

We don't have a description for Glyceryl Polyacrylate.

Disliked Full details ->
Arbutin Antioxidant, Bleaching, Skin Conditioning
Antioxidant IconGood for Dark Spots IconGood for Scar Healing Icon
AntioxidantAntioxidant Icon 2 Benefits

Arbutin is derived from the bearberry plant. It helps even out skin tone and reduce hyperpigmentation.

Polyporus Umbellatus Extract Skin Protecting

We don't have a description for Polyporus Umbellatus Extract.

Unknown Full details ->
Menthol Masking, Refreshing
May cause irritation IconEU Allergen IconMay worsen Rosacea Icon
3 Concerns

Menthol is a compound found in mint plants, such as peppermint. In its pure form, it is a clear crystalline substance.

Very Disliked Full details ->
Phenoxyethanol Preservative
Preservative Icon
PreservativePreservative Icon

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

Very Disliked Full details ->

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Skin Conditioning, Solvent
Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!

Learn more about Water
Antimicrobial, Astringent, Masking
Very Disliked

Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.

This ingredient gets a bad rep because it is irritating and drying - mostly due to its astringent property. Astringents draw out natural oils in tissue, constricting pores and leaving your skin dried out.

However, alcohol denat. is not all that bad.

Due to its low molecular weight, alcohol denat. tends to evaporate quickly. One study on pig skin found half of applied alcohol evaporated in 10 seconds and less than 3% stayed on skin.

This also helps other ingredients become better absorbed upon application.

Studies are conflicted about whether this ingredient causes skin dehydration. One study from 2005 found adding emollients to propanol-based sanitizer decreased skin dryness and irritation. Another study found irritation only occurs if your skin is already damaged.

Small amounts of alcohol are generally tolerated by oily skin or people who live in humid environments.

The rule of thumb is if this alcohol is near the end of an ingredients list, it will probably not affect your skin much.

Also...

This ingredient has antimicrobial and solvent properties.

The antimicrobial property helps preserve products and increase their shelf life. As a solvent, it helps dissolve other ingredients.

Other types of astringent alcohols include:

Learn more about Alcohol Denat.
Buffering, Emulsifying, Masking
Very Disliked

Triethanolamine is an emulsifier and pH adjuster. It is created using ethylene oxide and ammonia. This gives Triethanolamine a nitrogen core and a similar scent to ammonia.

As an emulsifier, it prevents ingredients from separating and enhances texture by adding volume to a product.

PH adjusters are common in cosmetic products. The pH of a product can affect the effectiveness of other ingredients. A product with a high pH may also irritate the skin.

Learn more about Triethanolamine
Humectant, Skin Conditioning, Skin Protecting
Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin

We don't have a description for Polyporus Umbellatus Extract.

Antioxidant, Bleaching, Skin Conditioning
Loved

Arbutin is derived from the bearberry plant. It helps even out skin tone and reduce hyperpigmentation.

This ingredient has the ability to block tyrosinase, an enzyme that starts the process of skin darkening. When applied to the skin, arbutin works at a slow pace. This can make it less irritating than similar ingredients.

Kojic Acid is a similar ingredient.

Learn more about Arbutin
Preservative
Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Ingredient Ratings

Here's what our community thinks of the ingredients in these two products.

Pro-Heal Serum Advance
7
2
6
2
liked
mixed
disliked
not rated
Active Serum
5
1
5
2
liked
mixed
disliked
not rated

When to use

30 Routines
73% use in am
27% use in pm
93% use every day
When to use See routines that use it ->
35 Routines
17% use in am
83% use in pm
83% use every day
When to use See routines that use it ->