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Product Comparison

Here's our complete breakdown comparing the ingredients, attributes, and more of SkinBetter Science Alto Advanced Defense and Repair Serum versus Is Clinical Pro-Heal Serum Advance .

Published on July 21, 2022

Overview

What they are

These products are both reef safe serums. They have a total of 5 ingredients in common

Cool Features

They both contain Vitamin C and Vitamin E

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any common allergens, oils, parabens or silicones

What's Inside

They both contain fragrances

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that need an update? Let us know.

Serum American Brand United States
Serum American Brand United States

Serum

Serums are highly concentrated with ingredients to provide skin with benefits. They should be used after cleansing and before moisturizing.

Serum

Serums are highly concentrated with ingredients to provide skin with benefits. They should be used after cleansing and before moisturizing.

Price

Shop

Buy Alto Advanced Defense and Repair Serum

Shop

Buy Pro-Heal Serum Advance

Starts at $71.34

Ingredient Info

Click any item below to learn more and view relevant ingredients.
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free
alcohol-free
silicon-free
fragrance-free
sulfate-free
paraben-free
oil-free
fungal-acne safe
reef-safe
eu-allergen-free
vegan
cruelty-free

At a glance

Click on any of the items below to learn more

Notable Ingredients

Vitamin C
Vitamin E (2)
Niacinamide
Ceramides (3)
Peptides

Benefits

Hydrating (7)
Good For Oily Skin
Redness Reducing (7)
Reduces Irritation (5)
Skin Texture
Reduces Large Pores (2)
Anti-Aging (7)
Dark Spots (3)
Scar Healing
Acne Fighting (2)
Brightening (4)

Concerns

May Worsen Oily Skin (2)
Acne Trigger (2)
Irritating

Notable Ingredients

Retinoid
Vitamin C
Vitamin E

Benefits

Hydrating (2)
Good For Oily Skin
Redness Reducing
Skin Texture (2)
Reduces Large Pores
Anti-Aging (3)
Dark Spots (3)
Scar Healing (4)
Acne Fighting
Brightening (4)

Concerns

Drying (2)
May Worsen Oily Skin (2)
Irritating (3)
Rosacea
Eczema (3)
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Ingredients Compared

Ingredients that are highlighted in purple are present in both products.

WaterButylene GlycolPropanediolEthylhexyl OlivateCetearyl AlcoholChlorogenic AcidsNiacinamideLauryl LactateDimethyl IsosorbidePyrroloquinoline Quinone Allyl EsterHydrolyzed Sodium HyaluronateGlycyrrhiza Glabra Root ExtractAscorbyl TetraisopalmitateErgothioneineBenzylidene DimethoxydimethylindanoneArabidopsis Thaliana ExtractCarnosineCamellia Sinensis Leaf ExtractVitis Vinifera Seed ExtractTheobroma Cacao Seed Extract Curcuma Longa Root ExtractOlea Europaea Fruit ExtractEuterpe Oleracea Fruit ExtractTrifluoroacetyl Tripeptide-2Buddleja Officinalis Flower ExtractCoffea Arabica Leaf Cell ExtractCrocus Sativus Leaf Cell Culture ExtractSuperoxide DismutaseUbiquinonePlankton ExtractMicrococcus LysateArginineZingiber Officinale Root ExtractCeramide NPCeramide APCeramide EOPLinoleic AcidLinolenic AcidSea Whip ExtractBisabololTocopherolTocopheryl AcetateCholesterolPhytosphingosineJojoba EstersSodium PCAPentylene GlycolMethyl Gluceth-20GlycerinHelianthus Annuus Seed WaxAcacia Decurrens Flower WaxLecithinSodium Lauroyl LactylateDicetyl PhosphatePropanediol Dicaprylate/CapratePolyglycerin-3Ceteth-20 PhosphateDiisostearyl MalateXanthan GumSteareth-2Acacia Senegal GumPentaerythrityl Tetra-Di-T-Butyl HydroxyhydrocinnamateCarbomerAcrylates/C10-30 Alkyl Acrylate CrosspolymerDextranRicinoleth-40Sodium HydroxideCitric AcidSodium PhytateEthylhexylglycerinPhenoxyethanol

Ingredients Side-by-side

Ingredients that are highlighted in purple are present in both products.

Learn more about what what Com. / Irr. ratings are

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Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1
What it does: Skin Conditioning, Solvent
Community Rating: Loved

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. Talk about multi-purpose! If you see this, drink a glass of water. Stay hydrated!

Learn more about Water

SkinBetter Science Alto Advanced Defense and Repair Serum contains this as ingredient number 1.

Is Clinical Pro-Heal Serum Advance contains this as ingredient number 1.

2
What it does: Antioxidant, Masking, Skin Conditioning
Community Rating: Liked

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol

SkinBetter Science Alto Advanced Defense and Repair Serum contains this as ingredient number 41.

Is Clinical Pro-Heal Serum Advance contains this as ingredient number 8.

3
What it does: Skin Conditioning, Solvent
Community Rating: Mixed

Pentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.

The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.

This property also makes Pentylene Glycol a great texture enhancer. It can help thicken or emulsify a product. Emulsifiers help stabilize a product. It does this by preventing certain ingredients from separating.

Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.

Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.

Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.

Learn more about Pentylene Glycol

SkinBetter Science Alto Advanced Defense and Repair Serum contains this as ingredient number 47.

Is Clinical Pro-Heal Serum Advance contains this as ingredient number 5.

4
What it does: Humectant, Skin Conditioning, Skin Protecting, Solvent
Community Rating: Loved

Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.

A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin

SkinBetter Science Alto Advanced Defense and Repair Serum contains this as ingredient number 49.

Is Clinical Pro-Heal Serum Advance contains this as ingredient number 9.

5
What it does: Preservative
Community Rating: Very Disliked

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent germ and microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

SkinBetter Science Alto Advanced Defense and Repair Serum contains this as ingredient number 71.

Is Clinical Pro-Heal Serum Advance contains this as ingredient number 17.

Here's what our community thinks of the ingredients in these two products.

45% are loved or liked
14% have mixed ratings
15% are disliked or very disliked
25% have no rating yet
41% are loved or liked
6% have mixed ratings
35% are disliked or very disliked
18% have no rating yet

Usage

Here's some more info on how this product is used by our community.

When to use

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Alternatives

Our Dupe Finder has found 4 potential alternatives that have similar ingredients to SkinBetter Science Alto Advanced Defense and Repair Serum.

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Our Dupe Finder has found 50 potential alternatives that have similar ingredients to Is Clinical Pro-Heal Serum Advance.

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