Dr.Leo 377 VC Whitening & Spot Fading Cream Versus Dr.Leo 5% Panthenol Anti-Acne Soothing Water Gel
Updated on April 02, 2025
Overview
What they are
These products are both cruelty-free and reef safe general moisturizers. They have a total of 12 ingredients in common
Cool Features
They both contain ceramides
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin and scar healing
Free From
They both do not contain any harsh alcohols, common allergens, parabens or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Dr.Leo 377 VC Whitening & Spot Fading Cream 50 ingredients
Dr.Leo 5% Panthenol Anti-Acne Soothing Water Gel 33 ingredients
What's inside
What's inside
At a glance
Click on any of the items below to learn more
Dr.Leo 377 VC Whitening & Spot Fading Cream 50 ingredients
Dr.Leo 5% Panthenol Anti-Acne Soothing Water Gel 33 ingredients
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningCyclopentasiloxane
Emollient
Niacinamide
Smoothing
Butylene Glycol
Humectant
Isododecane
EmollientVinyl Dimethicone/Methicone Silsesquioxane Crosspolymer
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Silica
Abrasive
Panthenol
Skin Conditioning
3-O-Ethyl Ascorbic Acid
Skin Conditioning
Neopentyl Glycol Diheptanoate
EmollientMethyl Gluceth-20
Humectant
PEG-40 Hydrogenated Castor Oil
Emulsifying
Pentylene Glycol
Skin Conditioning1,2-Hexanediol
Skin Conditioning
C12-15 Alkyl Benzoate
AntimicrobialHydroxyacetophenone
Antioxidant
Corallina Officinalis Extract
Skin Conditioning
PPG-26-Buteth-26
Skin ConditioningMaltodextrin
Absorbent
Allantoin
Skin Conditioning
Tocopheryl Acetate
Antioxidant
1-Methylhydantoin-2-Imide
Skin ConditioningPaeonia Albiflora Root Extract
Skin ConditioningCaprylhydroxamic Acid
Sodium Metabisulfite
Antioxidant
Centella Asiatica Leaf Extract
Skin Conditioning
Camellia Sinensis Leaf Extract
Antimicrobial
Propylene Glycol
Humectant
Phenyl Trimethicone
Skin Conditioning
C13-14 Isoparaffin
Emollient
Parfum
Masking
Disodium EDTA
Polyacrylate-13
Polyisobutene
Laureth-7
EmulsifyingCarbomer
Emulsion StabilisingSodium Polyacrylate
Absorbent
Glyceryl Stearate
Emollient
PEG-100 Stearate
PEG-8
HumectantCaprylyl Glycol
Emollient
Butyrospermum Parkii Butter
Skin Conditioning
Benzyl Glycol
SolventHydrolyzed Glycosaminoglycans
HumectantSodium Hyaluronate
Humectant
Sodium Acetylated Hyaluronate
Humectant
Ceramide AP
Skin Conditioning
Ceramide EOP
Skin Conditioning
Ceramide NP
Skin Conditioning
Water, Cyclopentasiloxane, Niacinamide, Butylene Glycol, Isododecane, Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Silica, Panthenol, 3-O-Ethyl Ascorbic Acid, Neopentyl Glycol Diheptanoate, Methyl Gluceth-20, PEG-40 Hydrogenated Castor Oil, Pentylene Glycol, 1,2-Hexanediol, C12-15 Alkyl Benzoate, Hydroxyacetophenone, Corallina Officinalis Extract, PPG-26-Buteth-26, Maltodextrin, Allantoin, Tocopheryl Acetate, 1-Methylhydantoin-2-Imide, Paeonia Albiflora Root Extract, Caprylhydroxamic Acid, Sodium Metabisulfite, Centella Asiatica Leaf Extract, Camellia Sinensis Leaf Extract, Propylene Glycol, Phenyl Trimethicone, C13-14 Isoparaffin, Parfum, Disodium EDTA, Polyacrylate-13, Polyisobutene, Laureth-7, Carbomer, Sodium Polyacrylate, Glyceryl Stearate, PEG-100 Stearate, PEG-8, Caprylyl Glycol, Butyrospermum Parkii Butter, Benzyl Glycol, Hydrolyzed Glycosaminoglycans, Sodium Hyaluronate, Sodium Acetylated Hyaluronate, Ceramide AP, Ceramide EOP, Ceramide NP
Water
Skin ConditioningPanthenol
Skin Conditioning
Propylene Glycol
Humectant
Methyl Gluceth-10
EmulsifyingPPG-30
Skin ConditioningPEG/PPG-17/6 Copolymer
SolventEctoin
Skin Conditioning
Madecassoside
Antioxidant
Centella Asiatica Extract
Cleansing
Asiaticoside
Antioxidant
Lactobacillus/Soymilk Ferment Filtrate
Skin ConditioningChlorella Vulgaris Extract
Skin Conditioning
1,2-Hexanediol
Skin Conditioning
Hydroxyacetophenone
Antioxidant
Carbomer
Emulsion StabilisingArginine
Masking
Butylene Glycol
Humectant
Portulaca Oleracea Extract
Skin Conditioning
Ceramide NP
Skin Conditioning
Ceramide AP
Skin Conditioning
Ceramide As
Skin Conditioning
Ceramide Ns
Skin Conditioning
Ceramide EOP
Skin Conditioning
Erythritol
Humectant
Glycerin
Humectant
Disodium EDTA
Pentylene Glycol
Skin ConditioningLaminaria Digitata Extract
Skin Protecting
Hydrogenated Lecithin
Emulsifying
Cetyl-Pg Hydroxyethyl Palmitamide
Skin ConditioningCholesterol
Emollient
CI 19140
Cosmetic ColorantCI 42090
Cosmetic ColorantWater, Panthenol, Propylene Glycol, Methyl Gluceth-10, PPG-30, PEG/PPG-17/6 Copolymer, Ectoin, Madecassoside, Centella Asiatica Extract, Asiaticoside, Lactobacillus/Soymilk Ferment Filtrate, Chlorella Vulgaris Extract, 1,2-Hexanediol, Hydroxyacetophenone, Carbomer, Arginine, Butylene Glycol, Portulaca Oleracea Extract, Ceramide NP, Ceramide AP, Ceramide As, Ceramide Ns, Ceramide EOP, Erythritol, Glycerin, Disodium EDTA, Pentylene Glycol, Laminaria Digitata Extract, Hydrogenated Lecithin, Cetyl-Pg Hydroxyethyl Palmitamide, Cholesterol, CI 19140, CI 42090
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.Â
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservativesÂ
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCarbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.
A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.
Ceramide AP is a type of Ceramide.
Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. Having a strong skin barrier leads to more firm and hydrated skin.
They are known for their ability to hold water and thus are a great ingredient for dry skin. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.
If you would like to eat ceramides, sweet potatoes contain a small amount.
Read more about other common types of ceramides here:
Ceramide NP
Ceramide EOP
Ceramide EOP is a type of Ceramide.
EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base.
Ceramides are intercellular lipids naturally found in our skin. They bind dead skin cells together to create a barrier. The ceramides in our skin have the ability to hold water to keep our skin hydrated.
Ceramides are an important building block for our skin barrier. A strong skin barrier helps with:
If you would like to eat ceramides, sweet potatoes contain a small amount.
Read more about other common types of ceramides here:
Learn more about Ceramide EOPCeramide NP is a type of ceramide.
Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.
Ceramides are an important building block for our skin barrier. A stronger barrier helps the skin look more firm and hydrated. By bolstering the skin ceramides act as a barrier against irritating ingredients. This can help with inflammation as well.
If you would like to eat ceramides, sweet potatoes contain a small amount.
Read more about other common types of ceramides here:
Ceramide AP
Ceramide EOP
Disodium EDTA plays a role in making products more stable by aiding other preservatives.
It is a chelating agent, meaning it neutralizes metal ions that may be found in a product.
Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.
Learn more about Disodium EDTAHydroxyacetophenone is antioxidant with skin conditioning and soothing properties. It also boosts the efficiency of preservatives.
This ingredient is not irritating or sensitizing.
Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolPentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolPropylene Glycol is an odorless, colorless liquid. As a humectant, it helps skin retain moisture. It also aids in delivering active ingredients.
Another role of this ingredient is preventing a product from melting or freezing. Propylene glycol also adds antimicrobrial properties to a product, elongating product lifespan.
This ingredient is considered an organic alcohol and commonly added into both cosmetics and foods.
Those with sensitive skin or conditions may develop a rash when using this ingredient.
Learn more about Propylene GlycolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterIngredient Ratings
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When to use
Dr.Leo 377 VC Whitening & Spot Fading Cream 50 ingredients
Dr.Leo 5% Panthenol Anti-Acne Soothing Water Gel 33 ingredients
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