Dr. Dennis Gross Skincare Alpha Beta pH Balance Replenishing Cream Versus Skinfix Barrier+ Skin Barrier Restoring Gel Cream
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningButylene Glycol
HumectantC13-16 Isoalkane
SolventCetearyl Alcohol
EmollientCaprylic/Capric Triglyceride
MaskingSodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingHeptyl Undecylenate
EmollientGlyceryl Behenate
EmollientStearyl Dimethicone
EmollientSaccharide Isomerate
HumectantMagnesium PCA
HumectantManganese PCA
HumectantPhytic Acid
Sodium PCA
HumectantLinoleic Acid
CleansingPhospholipids
Skin ConditioningCopper PCA
HumectantInonotus Obliquus Extract
Skin ConditioningLactic Acid
BufferingSodium Hyaluronate
HumectantNiacinamide
SmoothingAloe Barbadensis Leaf Juice
Skin ConditioningBisabolol
AntioxidantCentella Asiatica Extract
CleansingPhytosterols
Skin ConditioningAdenosine
Skin ConditioningSalicylic Acid
MaskingAloe Barbadensis Leaf Extract
EmollientCaulerpa Lentillifera Extract
Citrus Sinensis Fruit Extract
AntioxidantCocos Nucifera Fruit Extract
EmollientCitrullus Lanatus Fruit Extract
Skin ConditioningHydrolyzed Soy Protein
HumectantZinc PCA
HumectantGlycolic Acid
BufferingGlycerin
HumectantPentylene Glycol
Skin ConditioningEthylhexylglycerin
Skin ConditioningDimethicone
EmollientDimethicone Crosspolymer-3
Skin ConditioningPolyglyceryl-10 Laurate
Skin ConditioningHydrogenated Lecithin
EmulsifyingIsohexadecane
EmollientPotassium Cetyl Phosphate
EmulsifyingIsododecane
EmollientPotassium Chloride
Sodium Chloride
MaskingCalcium Chloride
AstringentTocopherol
AntioxidantCeteareth-20
CleansingSorbitan Oleate
EmulsifyingPolysorbate 80
EmulsifyingSodium Hydroxide
BufferingSodium Bicarbonate
AbrasiveSodium Citrate
BufferingCitric Acid
BufferingPhenoxyethanol
PreservativeBenzyl Alcohol
PerfumingSodium Benzoate
MaskingPotassium Sorbate
PreservativeWater, Butylene Glycol, C13-16 Isoalkane, Cetearyl Alcohol, Caprylic/Capric Triglyceride, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Heptyl Undecylenate, Glyceryl Behenate, Stearyl Dimethicone, Saccharide Isomerate, Magnesium PCA, Manganese PCA, Phytic Acid, Sodium PCA, Linoleic Acid, Phospholipids, Copper PCA, Inonotus Obliquus Extract, Lactic Acid, Sodium Hyaluronate, Niacinamide, Aloe Barbadensis Leaf Juice, Bisabolol, Centella Asiatica Extract, Phytosterols, Adenosine, Salicylic Acid, Aloe Barbadensis Leaf Extract, Caulerpa Lentillifera Extract, Citrus Sinensis Fruit Extract, Cocos Nucifera Fruit Extract, Citrullus Lanatus Fruit Extract, Hydrolyzed Soy Protein, Zinc PCA, Glycolic Acid, Glycerin, Pentylene Glycol, Ethylhexylglycerin, Dimethicone, Dimethicone Crosspolymer-3, Polyglyceryl-10 Laurate, Hydrogenated Lecithin, Isohexadecane, Potassium Cetyl Phosphate, Isododecane, Potassium Chloride, Sodium Chloride, Calcium Chloride, Tocopherol, Ceteareth-20, Sorbitan Oleate, Polysorbate 80, Sodium Hydroxide, Sodium Bicarbonate, Sodium Citrate, Citric Acid, Phenoxyethanol, Benzyl Alcohol, Sodium Benzoate, Potassium Sorbate
Water
Skin ConditioningSqualane
EmollientPropanediol
SolventJojoba Oil/Macadamia Seed Oil Esters
Skin ConditioningTriheptanoin
Skin ConditioningNiacinamide
SmoothingSaccharide Isomerate
HumectantAmmonium Acryloyldimethyltaurate/Vp Copolymer
Squalene
EmollientZinc PCA
HumectantHydrolyzed Hyaluronic Acid
HumectantGlycerin
HumectantCamellia Sinensis Seed Extract
HumectantAllantoin
Skin ConditioningPhytosteryl Macadamiate
Skin ConditioningPhytosterols
Skin ConditioningAcetyl Glutamine
Skin ConditioningLecithin
EmollientCaprylyl Glycol
EmollientAmylopectin
Sodium Hyaluronate
HumectantFolic Acid
Skin ConditioningOligopeptide-3
Skin ConditioningBacillus/Soybean Ferment Extract
Skin ConditioningOligopeptide-1
Skin ConditioningOligopeptide-2
Skin ConditioningHexapeptide-11
Skin ConditioningTocopherol
AntioxidantLithothamnion Calcareum Extract
Skin ConditioningLactic Acid
BufferingGlucose
HumectantAcetyl Heptapeptide-4
HumectantC14-22 Alcohols
Emulsion StabilisingC12-20 Alkyl Glucoside
EmulsifyingEthylhexylglycerin
Skin ConditioningTrisodium Ethylenediamine Disuccinate
Potassium Sorbate
PreservativeCitric Acid
BufferingSodium Citrate
BufferingPentylene Glycol
Skin ConditioningSodium Benzoate
MaskingXanthan Gum
EmulsifyingPhenoxyethanol
PreservativeWater, Squalane, Propanediol, Jojoba Oil/Macadamia Seed Oil Esters, Triheptanoin, Niacinamide, Saccharide Isomerate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Squalene, Zinc PCA, Hydrolyzed Hyaluronic Acid, Glycerin, Camellia Sinensis Seed Extract, Allantoin, Phytosteryl Macadamiate, Phytosterols, Acetyl Glutamine, Lecithin, Caprylyl Glycol, Amylopectin, Sodium Hyaluronate, Folic Acid, Oligopeptide-3, Bacillus/Soybean Ferment Extract, Oligopeptide-1, Oligopeptide-2, Hexapeptide-11, Tocopherol, Lithothamnion Calcareum Extract, Lactic Acid, Glucose, Acetyl Heptapeptide-4, C14-22 Alcohols, C12-20 Alkyl Glucoside, Ethylhexylglycerin, Trisodium Ethylenediamine Disuccinate, Potassium Sorbate, Citric Acid, Sodium Citrate, Pentylene Glycol, Sodium Benzoate, Xanthan Gum, Phenoxyethanol
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinLactic Acid is another well-loved alpha hydroxy acid (AHA). It is gentler than glycolic acid but still highly effective.
Its main role is to exfoliate the surface of the skin by loosening the “glue” that holds dead skin cells together. Shedding those old cells leads to smoother, softer, and more even-toned skin.
Because lactic acid molecules are larger than glycolic acid, they don’t penetrate as deeply. This means they’re less likely to sting or irritate, making it a great choice for beginners or those with sensitive skin.
Like glycolic acid, it can:
Lactic acid also acts as a humectant (like hyaluronic acid). It can draw water into the skin to improve hydration and also plays a role in the skin's natural moisturizing factor (NMF) in the form of sodium lactate.
Studies show it can boost ceramide production to strengthen the skin barrier and even help balance the skin’s microbiome.
To get results, choose products with a pH between 3-4.
Lower strengths (5-12%) focus on surface exfoliation; higher strengths (12% and up) can reach deeper in the dermis (deeper, supportive layer) to improve skin texture and firmness over time.
Though it was originally derived from milk, most modern lactic acid used in skincare is vegan. It is made through non-dairy fermentation to create a bio-identical and stable form suitable for all formulations.
When lactic acid shows up near the end of an ingredient list, it usually means the brand added just a tiny amount to adjust the product’s pH.
Legend has it that Cleopatra used to bathe in sour milk to help reduce wrinkles.
Lactic acid is truly a gentle multitasker: it exfoliates, hydrates, strengthens, and brightens. It's a great ingredient for giving your skin a smooth, glowing, and healthy look without the harshness of stronger acids.
Read more about some other popular AHA's here:
Learn more about Lactic AcidNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamidePentylene glycol is typically used within a product to thicken it. It also adds a smooth, soft, and moisturizing feel to the product. It is naturally found in plants such as sugar beets.
The hydrophilic trait of Pentylene Glycol makes it a humectant. As a humectant, Pentylene Glycol helps draw moisture from the air to your skin. This can help keep your skin hydrated.
This property also makes Pentylene Glycol a great texture enhancer. It can also help thicken or stabilize a product.
Pentylene Glycol also acts as a mild preservative and helps to keep a product microbe-free.
Some people may experience mild eye and skin irritation from Pentylene Glycol. We always recommend speaking with a professional about using this ingredient in your routine.
Pentylene Glycol has a low molecular weight and is part of the 1,2-glycol family.
Learn more about Pentylene GlycolPhenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.
It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.
Phytosterols are plant-derived sterols (you can think of them as the plant world's version of cholesterol). In cosmetics, this ingredient is usually sourced from soybean, rice bran, shea, sunflower, and other seed oils.
The main actors in this group are β-sitosterol, campesterol, and stigmasterol (the CIR covers 27 phytosterols).
They work by fitting perfectly into your stratum corneum's lipid matrix since they're structurally similar to cholesterol. Here, they reinforce your skin's barrier.
One small in vivo human study showed topical soybean phytosterols sped up barrier recovery within three days on tape-stripped skin.
Broader research credits them with:
Formulation use typically sit under 5%.
Testing in soy-allergic subjects found no sensitization signals, but be sure to patch test if you are unsure or have existing allergies.
Learn more about PhytosterolsPotassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Learn more about Potassium SorbateSaccharide Isomerate comes from sugars found in corn. It is a skin hydrator.
The structure of this ingredient can be altered to be more similar to the carbohydrates found in our skin. This ability to mimic our skin gives it hydrating properties.
Specifically, saccharide Isomerate is a humectant. Humectants draw moisture from the air to our skin.
Research shows Saccharide Isomerate to be an effective moisturizer.
Learn more about Saccharide IsomerateSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateSodium Citrate is the sodium salts of citric acid. In skincare, it is used to alter pH levels and acts as a preservative.
Its main functions are to maintain the pH of a product and neutralize metal ions.
The acidity of our skin is maintained by our glands and skin biome; normal pH level of skin is slightly acidic (~4.75-5.5).
Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.
Learn more about Sodium CitrateSodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateTocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterZinc PCA (or "zinc salt") differs slightly from zinc itself. PCA stands for pyrrolidone carboxylic acid. However, Zinc PCA comes from zinc.
It can help reduce redness, regulate sebum, and promote the general healing process of the skin.
Zinc PCA tends to be especially useful for those with oily, acne-prone skin. It's certainly an ingredient worth trying out!
Learn more about Zinc PCA