Physician's Formula Killer Curves Mascara Black

Physician's Formula Killer Curves Mascara

Color: Black
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Overview

What it is

Mascara with 67 ingredients that contains BHA, exfoliants, peptides and Vitamin E

Cool Features

It is cruelty-free and reef safe

Suited For

It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

It doesn't contain any common allergens, fragrances, parabens, silicones or sulfates

Fun facts

Physician's Formula is from United States.

We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.

What's inside

Ingredients List

31
26
10
Active Ingredients

Salicylic Acid

Masking
BHA IconPreservative IconHelps fight Acne IconHelps brighten skin IconGood for Oily Skin IconGood for Minimizing Pores IconGood for Skin Texture IconCan worsen Dry Skin IconMay worsen Eczema IconMay worsen Rosacea Icon
Inactive Ingredients

Water

Skin Conditioning

Synthetic Beeswax

Emulsion Stabilising
Not safe for Fungal Acne Icon

Synthetic Wax

Abrasive
Exfoliant IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon

Pisum Sativum Peptide

Skin Conditioning
Peptide IconHelps with Anti-Aging IconHelps hydrate Dry Skin Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin IconGood for Barrier Repair Icon

Glyceryl Stearate

Emollient
1 / 0 Not safe for Fungal Acne Icon

Oryza Sativa Bran Wax

Skin Conditioning
Helps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Palmitic Acid

Emollient
2 / 0 Helps hydrate Dry Skin IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon

Ptfe

Stearic Acid

Cleansing
2-3 / 0 Helps hydrate Dry Skin IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon

Tromethamine

Buffering

Copernicia Cerifera Wax

1 / 0 Not safe for Fungal Acne Icon

Vp/Eicosene Copolymer

Polybutene

Pvp

Emulsion Stabilising
0 / 0

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce irritation IconHelps reduce Skin Redness IconGood for Scar Healing IconGood for Barrier Repair Icon

Phenoxyethanol

Preservative
Preservative Icon

Hydroxyethylcellulose

Emulsion Stabilising

Cetearyl Nonanoate

Emollient

Triticum Vulgare Bran Extract

Skin Conditioning

Caprylyl Glycol

Emollient
Fatty Alcohol Icon

Oleic Acid

Emollient
Bad for Acne Prone Skin IconMay worsen Oily Skin IconNot safe for Fungal Acne Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconGood for Barrier Repair Icon

Hexylene Glycol

Emulsifying
0-2 / 0-1

Ethylhexylglycerin

Skin Conditioning

Tocopheryl Acetate

Antioxidant
0 / 0 Vitamin E IconAntioxidant IconHelps brighten skin Icon

Ethylhexyl Isononanoate

Emollient

Pullulan

Leuconostoc/Radish Root Ferment Filtrate

Antimicrobial
Not safe for Fungal Acne Icon

Tetrasodium EDTA

Linoleic Acid

Cleansing
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Scar Healing IconGood for Dark Spots IconGood for Barrier Repair IconNot safe for Fungal Acne Icon

Sodium PCA

Humectant
0 / 0 Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Barrier Repair Icon

PPG-26-Buteth-26

Skin Conditioning

Sodium Lactate

Buffering
Helps hydrate Dry Skin Icon

PEG-40 Hydrogenated Castor Oil

Emulsifying
Oil IconNot safe for Fungal Acne Icon

Arginine

Masking
Helps hydrate Dry Skin IconGood for Scar Healing Icon

Sodium Acetate

Buffering

Troxerutin

Skin Conditioning
Helps reduce Skin Redness Icon

Aspartic Acid

Masking
Helps hydrate Dry Skin Icon

Acacia Seyal Gum Extract

Humectant

PCA

Humectant
Helps hydrate Dry Skin Icon

Isopropyl Alcohol

Solvent
0 / 0 Alcohol IconCan worsen Dry Skin IconMay worsen Eczema IconMay cause irritation IconMay worsen Rosacea Icon

Cellulose

Absorbent
Good for Oily Skin Icon

Sorbitol

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Barrier Repair Icon

Glycine

Buffering
Helps hydrate Dry Skin Icon

Alanine

Masking
Helps hydrate Dry Skin Icon

Camellia Oleifera Seed Oil

Skin Conditioning
Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Citric Acid

Buffering
AHA IconHelps brighten skin IconMay worsen Rosacea Icon

Potassium Sorbate

Preservative
Preservative Icon

Serine

Masking
Helps hydrate Dry Skin Icon

Acacia Senegal Gum

Masking

Trehalose

Humectant
Helps with Anti-Aging IconHelps hydrate Dry Skin IconGood for Barrier Repair Icon

Valine

Masking

Proline

Skin Conditioning
Helps hydrate Dry Skin Icon

Threonine

Helps hydrate Dry Skin Icon

Isoleucine

Skin Conditioning

Apigenin

Antioxidant
Antioxidant Icon

Sodium Benzoate

Masking
Preservative Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps with Anti-Aging IconHelps hydrate Dry Skin IconHelps brighten skin IconHelps reduce Skin Redness IconGood for Dark Spots IconGood for Barrier Repair Icon

Oleanolic Acid

Skin Conditioning

Histidine

Humectant
Helps with Anti-Aging IconHelps hydrate Dry Skin Icon

Benzoic Acid

Masking
Preservative IconMay worsen Eczema Icon

Myristoyl Pentapeptide-17

Skin Conditioning
Peptide IconNot safe for Fungal Acne Icon

Phenylalanine

Masking
Helps hydrate Dry Skin Icon

Biotinoyl Tripeptide-1

Peptide Icon

CI 77499

Cosmetic Colorant

Key Ingredients

Benefits

Concerns

Ingredients Explained

Skin Conditioning, Solvent

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Learn more about Water
Emulsion Stabilising

Synthetic beeswax is created to be identical in structure to beeswax. It possesses the same occlusive and emulsion properties.

A blend of fatty acid esters, fatty acids, and alcohols are used to create synthetic beeswax. Whether or not this ingredient is vegan depends on the source. Sometimes, lanolin is used for its creation.

This ingredient may not be Malassezia folliculitis, or fungal-acne safe.

Learn more about Synthetic Beeswax
Abrasive, Emulsion Stabilising, Masking

Synthetic Wax is created from fossil fuels such as natural gas. It is used to enhance texture, adjust pH, and as an occlusive.

It may also be used as an abrasive ingredient to exfoliate the skin.

Synthetic Wax may not be fungal acne safe.

Learn more about Synthetic Wax
Skin Conditioning

This plant-based protein comes from peas.

According to the manufacturer, this peptide is created from the process of hydrolysis, or the process of breaking down chemical compounds with water. They claim this ingredient has antioxidant, anti-aging, and hydrating benefits for both skin and hair.

Humectant, Masking, Skin Conditioning

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Learn more about Butylene Glycol
Emollient, Emulsifying

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Learn more about Glyceryl Stearate
Skin Conditioning

Oryza Sativa Bran Wax is wax from the outer layer of a rice kernel. It has moisturizing properties due to its polysaccharides and omega-3 fatty acids content.

This ingredient is a byproduct of milling rice, or the operation to produce a whole grain rice product.

Emollient, Emulsifying

Palmitic Acid is a fatty acid naturally found in our skin and in many plant and animal sources. In cosmetics, it is usually derived from palm oil. It serves many purposes in skincare, acting as a cleanser, emollient, and emulsifier.

Interestingly, topically applied Palmitic Acid can be elongated into longer chain fatty acids and ceramides. A 2019 study found low levels of Palmitic Acid lead to slower development of cells, suggesting it plays a role in keeping your skin's renewal process on track.

The CIR (Cosmetic Ingredient Review) panel determined it safe as used in cosmetics at concentrations up to 13%. It is non-irritating and non-sensitizing in clinical studies.

The culprit behind fungal acne, the Malassezia yeast, feeds on fatty acids with carbon chain lengths between C11-C24. Palmitic Acid, at C16, falls right into that sweet spot.

In vitro studies have shown that Palmitic Acid is one of the fatty acids that induce rapid Malassezia growth in lab settings.

It's worth noting that what feeds yeast in a lab doesn't necessarily feed it on your face since formulation and your skin's chemistry play a bigger role.

Learn more about Palmitic Acid

PTFE is a form of PFAS, or "Per- and polyfluoroalkyl substances". This ingredient has been used in commercial applications since the 1940's.

In cosmetics, PTFE is most commonly used as bulking agents, to improve consistency, or to improve texture.

PFAS compounds are currently under scrutiny due to possible health risks. This is mostly due to one type of PFAS: PFOA.

PFOA is no longer used in cosmetics and is highly restricted in many countries.

Today, PFAS are used widely in the medical field. They often play an important role in medical equipment such as catheters and medical implants.

In 2018, the Expert Panel for Cosmetic Ingredient Safety found PTFE to be safe for use in cosmetics and personal care productions.

This ingredient is commonly found in mascara (up to 13%) and hair bleach (up to 2.4%). Studies show this ingredient does not cause skin or eye irritation.

The EU allows PTFE to be used in cosmetics without restrictions.

All federal agencies do state further research about PFAS in cosmetics is needed.

Whether you choose to use this ingredient is a personal choice. We recommend adding this ingredient to your liked or disliked list so you can be notified anytime a product contains this ingredient.

Learn more about Ptfe
Cleansing, Emulsifying, Emulsion Stabilising

Stearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.

In cosmetics, it is a multitasker:

Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.

Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.

Learn more about Stearic Acid
Buffering, Masking

Tromethamine helps balance the pH and improve the texture of a product. It is synthetically created.

As an emulsifier, Tromethamine prevents oil and water ingredients from separating. This helps stabilize the product and elongate a product's shelf life. Tromethamine also makes a product thicker.

Tromethamine helps balance the pH level of a product. Normal pH level of skin is slightly acidic (~4.75-5.5). The acidity of our skin is maintained by our glands and skin biome. Being slightly acidic allows our skin to create an "acid mantle". This acid mantle is a thin barrier that protects our skin from bacteria and contaminants.

Oral Tromethanmine is an anti-inflammatory drug but plays the role of masking, adding fragrance, and/or balancing pH in skincare.

1,3-Propanediol, 2-amino-2-(hydroxymethyl)-

Learn more about Tromethamine

Copernicia Cerifera Wax comes from a palm tree native to Brazil; another name for this ingredient is Carnauba Wax.

This ingredient is used to thicken texture and also leaves behind a film when applied.

Fun fact: This wax has the highest melting point of all natural waxes and low solubility.

Learn more about Copernicia Cerifera Wax

We don't have a description for Vp/Eicosene Copolymer yet.

Polybutene is used to help control the viscosity of a product. This just means it helps adjusts the texture.

It is a polymer and does not get absorbed into the skin due to its large size.

Studies found this ingredient did not irritate skin in concentrations below 15%.

Learn more about Polybutene
Pvp
Emulsion Stabilising

Pvp is a water-soluble synthetic polymer and common hairstyling ingredient. It is a film-forming ingredient and used to "hold" specific shapes of hair.

In cosmetics, PVP helps products like sunscreens and color cosmetics last longer and wear more evenly.

It is less effective in high-humidity. It tends to draw moisture, but this moisture dismantles the structure and "hold".

PVP is generally well tolerated on skin and toxicity studies are negative for dermal irritation.

Learn more about Pvp
Skin Conditioning

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Learn more about Panthenol
Preservative

Phenoxyethanol is a preservative that has germicide, antimicrobial, and aromatic properties. Studies show that phenoxyethanol can prevent microbial growth. By itself, it has a scent that is similar to that of a rose.

It's often used in formulations along with Caprylyl Glycol to preserve the shelf life of products.

Emulsion Stabilising, Stabilising

Hydroxyethylcellulose is used to improve the texture of products. It is created from a chemical reaction involving ethylene oxide and alkali-cellulose. Cellulose is a sugar found in plant cell walls and help give plants structure.

This ingredient helps stabilize products by preventing ingredients from separating. It can also help thicken the texture of a product.

This ingredient can also be found in pill medicines to help our bodies digest other ingredients.

Learn more about Hydroxyethylcellulose
Emollient

We don't have a description for Cetearyl Nonanoate yet.

Skin Conditioning, Skin Protecting

This ingredient is also known as wheat bran. It has skin conditioning and protecting properties.

Emollient, Humectant, Skin Conditioning

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid or alcohol, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Learn more about Caprylyl Glycol
Emollient, Emulsifying

Oleic Acid is an Omega-9 fatty acid that can be found naturally in your skin's sebum and in many plant oils such as avocado and olive oil.

It is an emollient that helps soften skin and prevent moisture loss.

Research shows:

A 1998 study did find that applying oleic acid at higher concentrations may cause irritation and disrupt the skin barrier. Modern formulations typically use low levels that is well-tolerated.

The culprit behind fungal acne, the Malassezia yeast, feeds on fatty acids with carbon chain lengths between C11-C24. Oleic Acid, at C18, falls right into that sweet spot.

In vitro studies have shown that Oleic Acid is one of the fatty acids that induce rapid Malassezia growth in lab settings.

Learn more about Oleic Acid
Humectant, Skin Conditioning, Skin Protecting

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Learn more about Glycerin
Emulsifying, Skin Conditioning, Solvent

Hexylene Glycol is a multitasker ingredient that works as a solvent, humectant, emulsifier, viscosity reducer, and preservative booster.

It is able to dissolve both water and oil-soluble ingredients to stabilize tricky actives and make products spread more easily.

As a humectant, it pulls water into the skin. But it's a pretty minor moisturizing ingredient compared to other humectants, like glycerin.

Interestingly, it can act as a mild penetration enhancer. One in vitro study on human skin found a 12% concentration upped the absorption of mometasone furoate (a medicinal ingredient used to treat inflammatory skin conditions) up to 7%.

This ingredient is typically used at levels of 0.1-10% depending on the role it's playing.

A patch test study on eczema patients didn't find a significant increase in irritation versus the control group, but the potential for irritation rises at higher concentrations.

Learn more about Hexylene Glycol
Skin Conditioning

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Learn more about Ethylhexylglycerin
Antioxidant, Skin Conditioning

Tocopheryl Acetate is AKA Vitamin E. It is an antioxidant and protects your skin from free radicals. Free radicals damage the skin by breaking down collagen.

One study found using Tocopheryl Acetate with Vitamin C decreased the number of sunburned cells.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

Learn more about Tocopheryl Acetate

We don't have a description for Ethylhexyl Isononanoate yet.

Pullulan is a low viscosity polysaccharide (a long chain carbohydrate) with binding and film forming properties when dissolved in water. It is used to create a "silicone-like" or silky feel in cosmetics without adding viscosity.

According to a manufacturer, this ingredient's ability to easily dissolves makes it a great carrier for active ingredients.

Due to it being edible and tasteless, you'll likely find this ingredient in breath freshener strips. This ingredient is produced from the starch of the fungus, Aureobasidium pullulans.

Pullulan is stable over a broad-range of pH.

Learn more about Pullulan

Leuconostoc/Radish Root Ferment Filtrate is a natural preservative. It comes from fermenting radish roots with a bacteria called leuconostoc. The trade name for this ingredient is Leucidal.

Leuconostoc comes from lactic acid.

This ingredient has antimicrobial properties and helps prevent the growth of bacteria in a product.

Leuconostoc is used to make the traditional Korean side-dish, kimchi. It is also used to make sourdough bread (both incredibly yummy foods).

Learn more about Leuconostoc/Radish Root Ferment Filtrate

Tetrasodium EDTA is the salt formed from neutralizing ethylenediamine tetraacetic acid with sodium hydroxide. It is a chelating agent and used to prevent metal ions from binding to other ingredients. This helps keep the product and ingredients stable.

Tetrasodium EDTA comes as a white solid and is soluble in water.

Cleansing, Emollient, Skin Conditioning

Linoleic Acid is also known as Vitamin F. It is a fatty acid with emollient and skin conditioning properties. Our top layer of skin, or epidermis, contains high amounts of linoleic acid naturally.

Your body uses linoleic acid to build ceramides and prostaglandins. Ceramides keep your skin's barrier hydrated and strong while prosaglandins help control inflammation and healing. Needless to say, linoleic acid is crucial for having a strong skin barrier.

One study found applying linoleic acid rich sunflower oil to be more effective at repairing the skin barrier than oleic rich olive oil.

Linoleic acid is an essential fatty acid, meaning our bodies cannot create it on its own. We need to get linoleic acid through foods such as nuts and vegetable oils.

Acne-prone skin tends to have linoleic acid and high levels of oleic acid.

Linoleic acid can also help treat acne by softening sebum to prevent clogged pores. Another study found using 2.5% linoleic acid gel for 4 weeks showed a 25% reduction in small comedones.

This ingredient can also help lighten hyperpigmentation or sun spots by disrupting the melanin production process. It also helps your skin shed melanin pigment from your skin caused by UV exposure.

Due to its role in the production of the fatty acid prostaglandin, linoleic acid can also help reduce inflammation and support wound healing.

Linoleic acid is not always fungal-acne safe; it may trigger flare-ups in sensitive individuals.

Learn more about Linoleic Acid
Humectant, Skin Conditioning

Sodium PCA is the sodium salt of pyroglutamic acid. It is naturally occurring in our skin's natural moisturizing factors where it works to maintain hydration.

The PCA stands for pyrrolidone carboxylic acid, a natural amino acid derivative.

This ingredient has skin conditioning, anti-inflammatory, and humectant properties. Humectants help hydrate your skin by drawing moisture from the air. This helps keep your skin moisturized.

Learn more about Sodium PCA
Skin Conditioning

We don't have a description for PPG-26-Buteth-26 yet.

Buffering, Humectant

Sodium Lactate is the sodium salt of lactic acid, an AHA. It is a humectant and sometimes used to adjust the pH of a product.

This ingredient is part of our skin's NMF, or natural moisturizing factor. Our NMF is essential for the hydration of our top skin layers and plasticity of skin. NMF also influences our skin's natural acid mantle and pH, which protects our skin from harmful bacteria.

High percentages of Sodium Lactate can have an exfoliating effect.

Fun fact: Sodium Lactate is produced from fermented sugar.

Learn more about Sodium Lactate

Peg-40 Hydrogenated Castor Oil is derived from castor oil and polyethylene glycol (PEG). It is used as a emollient and emulsifier.

As an emulsifier, it helps prevent ingredients from separating. It also helps make the other ingredients more soluble; it is often used to solubilize fragrances. This increases spreadability and elongates shelf life in a product.

Emollients help soothe and soften the skin. They do this by creating a protective film on your skin. This barrier helps trap moisture and keeps your skin hydrated. Emollients may be effective at treating dry or itchy skin.

This ingredient may or may not be vegan, depending on the source.

Peg-40 Hydrogenated Castor Oil may not be fungal-acne safe. We recommend speaking with a professional if you have any questions or concerns.

Learn more about PEG-40 Hydrogenated Castor Oil
Masking, Skin Conditioning

Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.

It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.

A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.

Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.

One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.

Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.

Learn more about Arginine
Buffering, Masking

We don't have a description for Sodium Acetate yet.

Skin Conditioning

Troxerutin can help to reduce redness.

Masking, Skin Conditioning

Aspartic Acid is an amino acid that our bodies produce naturally. It is an antioxidant.

Our body uses Aspartic Acid to help build collagen and elastin. It also plays a role in hydrating skin.

We don't have a description for Acacia Seyal Gum Extract yet.

PCA
Humectant, Moisturising

PCA is derived from amino acids and is naturally found in our skin's barrier.

As a humectant, PCA helps draw and hold moisture to the skin. Studies show it is effective at helping the skin stay hydrated long-term.

Isopropyl Alcohol is more commonly known as rubbing alcohol. It is most commonly used as a solvent, meaning it helps other ingredients dissolve.

This ingredient is an astringent alcohol. Astringent alcohols may also irritate skin as they high amounts may strip away your skin's natural oils.

Other types of astringent alcohols include:

According to the National Rosacea Society based in the US, you should be mindful of products with these alcohols in the top half of ingredients.

Any type of sanitizing product will have high amounts of alcohol to help kill bacteria and viruses.

Learn more about Isopropyl Alcohol
Absorbent

Cellulose is the main component of plant cell walls. It is used as an emulsifier, absorbent, and texture enhancer.

This ingredient has many functions:

Fun fact: Cellulose is the most abundant form of organic polymer on Earth.

Learn more about Cellulose
Humectant, Masking, Skin Conditioning

Sorbitol is a sugar alcohol. It is a hydrating and moisturizing agent created from the reduction process of glucose.

Most sorbitol is usually made from potato starch. It is also found in fruits such as apples and pears.

As a humectant, Sorbitol helps draw water to the skin. This helps keep the skin hydrated. Sorbitol also helps create a thicker texture in products. You might find sorbitol in your toothpaste and other gels.

It is a non-irritating ingredient that is great for those with dry skin.

Sorbitol is a prebiotic. It helps promote the growth of healthy bacteria on your skin. The bacteria on your skin form a microbiome. This microbiome helps protect your skin from infection and harmful bacteria.

Learn more about Sorbitol
Buffering, Skin Conditioning

Glycine is the smallest amino acid and a key building block of collagen. It's part if your skin's Natural Moisturizing Factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

A study from 2022 found that an amino acid complex featuring taurine, arginine, and glycine significantly reduced skin irritation, improved redness, and accelerated the skin repair process.

Masking, Skin Conditioning

Alanine is an amino acid and is already found in the human body. Our skin uses alanine to build collagen, elastin, and keratin.

Skin Conditioning

Camellia Oleifera Seed Oil comes from a green tea plant native to China. It is closely related to Camellia sinensis. Both plants have very similar properties. This plant also has similar properties to olive oil.

This ingredient is rich in oleic acid. This makes it an effective moisturizer. By creating a thin film on the skin, Camellia Oleifera Seed Oil traps moisture within. This helps keep your skin smooth and hydrated.

The antioxidant and soothing properties of this ingredient come from Vitamin E and polyphenols.

The seed oil comes from the dried kernels of the plant.

Learn more about Camellia Oleifera Seed Oil
Buffering, Masking

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Read more about some other popular AHA's here:

Learn more about Citric Acid
Preservative

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Learn more about Potassium Sorbate
Masking, Skin Conditioning

Serine is a non-essential amino acid (your body makes it on its own!). It is a major player in your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.

Serine is one of your NMF's most abundant components that works as a skin-identical humectant. Its hydroxyl group grabs onto water molecules to boost hydration without any heaviness or occlusion.

Research on a hydrogel with serine confirmed this serine got delivered to your stratum corneum and demonstrated enhanced skin moisturization.

Interestingly serine also helps your skin produce filaggrin, a protein that keeps your skin barrier strong and used to create collagen.

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Acacia Senegal Gum has skin soothing, thickening, and formulation stabilizing properties. It comes from the Acacia tree that is native to sub-Saharan Africa.

Humectant, Moisturising

Trehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.

As a humectant, trehalose helps draw moisture from the air to your skin. This helps keep your skin hydrated.

Due to its antioxidant properties, trehalose may help with signs of aging. Antioxidants help fight free-radical molecules, unstable molecules that may damage your skin.

In medicine, trehalose and hyaluronic acid are used to help treat dry eyes.

Some animals, plants, and bacteria create trehalose as a source of energy to survive freeze or lack of water.

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Masking, Skin Conditioning

Valine is an essential amino acid. It is used by our bodies for tissue repair and muscle growth.

An essential amino acid is one in which our bodies cannot naturally produce so we must get them through diet. Foods such as eggs, dairy, red meat, and fish contain valine.

This ingredient can either be derived from an animal product or be synthetically created.

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Skin Conditioning

Proline is a non-essential amino acid, meaning your body can make it on its own. In skincare, it is a skin conditioning ingredient that keeps skin soft and hydrated.

It makes up about 23% of the collagen molecule (collagen is the protein responsible for keeping your skin firm) and is involved in your skin's natural hyaluronic acid production. When applied topically, proline can penetrate the skin fairly well due to its small molecular size.

Reviews of this ingredient have found it to be neither a dermal irritant nor a sensitizer.

Fun fact: Proline can be found in protein-rich foods like meat, fish, eggs, and dairy.

Learn more about Proline

Threonine is an amino-acid. It helps hydrate the skin and has antioxidant benefits.

Our skin uses threonine for creating collagen and elastin. Humans are not able to create threonine and must get it through eating foods such as fish, lentils, poultry, sesame seeds, and more.

Skin Conditioning

Isoleucine is an amino acid that helps reinforce our skin barrier. This amino acid plays a role in creating protein for the body.

Fun fact: Isoleucine is found in meat, fish, dairy, legumes, and nuts.

Antioxidant

Apigenin is an antioxidant.

Masking, Preservative

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

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Antioxidant, Masking, Skin Conditioning

Tocopherol (also known as Vitamin E) is a common antioxidant used to help protect the skin from free-radicals and strengthen the skin barrier. It's also fat soluble - this means our skin is great at absorbing it.

Vitamin E also helps keep your natural skin lipids healthy. Your lipid skin barrier naturally consists of lipids, ceramides, and fatty acids. Vitamin E offers extra protection for your skin’s lipid barrier, keeping your skin healthy and nourished.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Learn more about Tocopherol
Skin Conditioning

Oleanolic acid is a type of triterpene.

Triterpenes are chemical compounds found in various plants such as pomegranates, apples, basil, and rosemary. They have been shown to have anti-inflammatory and antioxidant properties.

Humectant, Skin Conditioning

Histidine is a semi-essential amino acid used by our bodies to create protein. It has humectant and skin conditioning properties.

Our bodies use histidine to create filaggrin - filaggrin is a structural protein that the skin uses in maintaining skin barrier.

One study found histidine and carnosine to be a dynamic duo for your skin:

Oral histidine has also been found to help with filaggrin-deficit skin disorders such as atopic dermatitis.

Why is it considered a semi-essential amino acid? This is because adults are able to create it but children must get it from their diet.

Learn more about Histidine
Masking, Preservative

Benzoic Acid is used to preserve and adjust the pH of products.

The antimicrobial property of Benzoic Acid helps elongate a product's shelf life. Its main role is to reduce fungi growth and is not found to be effective at fighting bacteria. Therefore Benzoic Acid is always added along with other preservatives.

In its pure form, Benzoic Acid looks like a white crystalline solid. It has slight solubility in water.

The name of Benzoic Acid comes from gum benzoin, which used to be the sole source of deriving this ingredient. Benzoic Acid is the most simple aromatic carboxylic acid.

Benzoic Acid is naturally occuring in strawberries, mustard, cinnamon, and cloves. It has a slight scent but is not considered to be a fragrance.

Learn more about Benzoic Acid
Skin Conditioning

Myristoyl Pentapeptide-17 isn't fungal acne safe and is a peptide.

Masking, Skin Conditioning

Phenylalanine is an amino acid. It is a skin soothing and hydrating ingredient. Amino acids play a crucial role in wound healing and skin hydration.

This ingredient is also used to help even out skin tone due to its ability to disrupt the melanin production process.

Two structures of phenylalanine exist: L-phenylalanine and D-phenylalanine. L-phenylalanine is essential, this means our bodies cannot produce it naturally and we must get it from foods. Our bodies convert D-phenylalanine to neurotransmitters, and D-phenylalanine is found in our bodies naturally.

Some foods that contain L-phenylalanine include eggs, soybeans, beef, milk.

Learn more about Phenylalanine

Biotinoyl Tripeptide-1 is a lab-made molecule that combines two parts: biotin (vitamin B7) and Tripeptide-1. Together, they form a peptide that’s often used in hair and eyelash products.

In-vitro studies show this ingredient helps hair bulb cells grow faster and product more structual proteins. This helps keep hair securely anchored in the follicle.

A small human study using a mascara with 2% Biotinoyl Tripeptide-1 reported lashes that were about 17% longer and 19% thicker after one month.

One study from 2025 compared topical spray vs. a combined tropical/oral treatment. The combination group saw greater increases in total hair count.

While these early results are encouraging, most of the data comes from in-vitro experiments (in test tubes) or small, short-term trials.

Biotinoyl Tripeptide-1 looks promising for supporting hair strength and growth but there’s not yet strong clinical evidence to confirm how well it works.

Learn more about Biotinoyl Tripeptide-1
Cosmetic Colorant

Ci 77499 is also hydrated iron III oxide. It is created from mixing red and black iron oxides. This helps give shades of darkness to a product.

Iron III oxides are classified as inorganic chemicals for coloring.

Masking, Preservative, Skin Conditioning

Salicylic Acid (also known as beta hydroxy acid or BHA) is a well-known ingredient for treating skin that struggles with acne and clogged pores. It exfoliates both the skin's surface and deep within the pores to help clear out buildup, control oil, and reduce inflammation.

Unlike AHAs (alpha hydroxy acids), salicylic acid is oil-soluble. This allows it to penetrate into pores which makes it especially effective for treating blackheads and preventing future breakouts.

Salicylic acid is also known for its soothing properties. It has a similar structure to aspirin and can calm inflamed or irritated skin, making it a good option for acne-prone skin that is also sensitive.

Concentrations of 0.5-2% are recognized by the U.S. FDA as an over-the-counter topical acne product.

It can cause irritation and/or dryness if one's skin already has a compromised moisture barrier, so it's best to focus on repairing that before introducing this ingredient into your routine.

While salicylic acid does not increase sun sensitivity, it’s still important to wear sunscreen daily to protect your skin.

If you are looking for the ingredient called BHA or Butylated Hydroxyanisole, click here.

Learn more about Salicylic Acid

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Physician's Formula is a American brand

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· Updated July 21, 2025 Added by anemone