MediCube Retinol-some 1.9% NMN Boosting Serum
A cruelty-free serum that contains hyaluronic acid, peptides, retinoid and vitamin c.
Overview
What it is
Serum with 29 ingredients that contains hyaluronic acid, peptides, retinoid and Vitamin C
Cool Features
It is cruelty-free and reef safe
Suited For
It has ingredients that are good for fighting acne, anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
It doesn't contain any harsh alcohols, common allergens, parabens, silicones or sulfates
Fun facts
MediCube is from South Korea.
We independently verify ingredients and our claims are backed by peer-reviewed research. Does this product need an update? Let us know.
What's inside (and what isn't)
Ingredients List
Dive into the full list of ingredients.
Caprylic/Capric Triglyceride
MaskingMacadamia Ternifolia Seed Oil
EmollientButylene Glycol
HumectantHydrogen
AntioxidantCholesterol
EmollientPolyglyceryl-10 Laurate
Skin ConditioningPhytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate
Skin ConditioningMethyl Di-T-Butyl Hydroxyhydrocinnamate
AntioxidantPotassium Cetyl Phosphate
EmulsifyingTris(Tetramethylhydroxypiperidinol) Citrate
UV AbsorberGlyceryl Citrate/Lactate/Linoleate/Oleate
EmulsifyingAluminum Starch Octenylsuccinate
AbsorbentGlycerin
HumectantRetinal
Skin ConditioningSqualane
EmollientWater
Skin ConditioningPolyquaternium-6
Sodium Hyaluronate Crosspolymer
HumectantNepeta Cataria Extract
TonicCaprylyl Glucoside
CleansingCamellia Japonica Flower Extract
EmollientPolyglyceryl-10 Oleate
Skin ConditioningPropanediol
SolventAcetyl Hexapeptide-8
HumectantAcetyl Tetrapeptide-9
Skin ConditioningAdenosine
Skin ConditioningCarnosine
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningAscorbic Acid
AntioxidantCaprylic/Capric Triglyceride, Macadamia Ternifolia Seed Oil, Butylene Glycol, Hydrogen, Cholesterol, Polyglyceryl-10 Laurate, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Methyl Di-T-Butyl Hydroxyhydrocinnamate, Potassium Cetyl Phosphate, Tris(Tetramethylhydroxypiperidinol) Citrate, Glyceryl Citrate/Lactate/Linoleate/Oleate, Aluminum Starch Octenylsuccinate, Glycerin, Retinal, Squalane, Water, Polyquaternium-6, Sodium Hyaluronate Crosspolymer, Nepeta Cataria Extract, Caprylyl Glucoside, Camellia Japonica Flower Extract, Polyglyceryl-10 Oleate, Propanediol, Acetyl Hexapeptide-8, Acetyl Tetrapeptide-9, Adenosine, Carnosine, Palmitoyl Tetrapeptide-7, Ascorbic Acid
Key Ingredients
Benefits
Concerns
Ingredients Explained
This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.
It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.
Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.
Learn more about Caprylic/Capric TriglycerideMacadamia Ternifolia Seed Oil is the fixed oil obtained from Macadamia nut.
Macadamia seed oil is rich in fatty acids, including oleic acid (45-75%), palmitoleic acid (7-33%), and palmitic acid (6-12%). They also contain various B vitamins, iron, and magnesium.
Palmitoleic acid has been shown to help soothe inflammation and promote wound healing. It is also naturally found in the fat of our skin.
Macadamia seed oil may not be malassezia folliculitis, or fungal-acne, safe.
Learn more about Macadamia Ternifolia Seed OilButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolHydrogen is an antioxidant.
Cholesterol is a class of organic molecules called lipids. It helps hydrate your skin and is essential to having a healthy skin barrier.
Our skin naturally contains cholesterol in the outermost layer. Besides cholesterol, it also contains ceramides and fatty acids. Cholesterol makes up about 1/4 of your skin's outer layer and barrier. Your skin barrier is responsible for keeping allergens and microbes out. Having a healthy skin barrier is also responsible for keeping your skin firm and plump.
Our bodies use cholestrol to create vitamin D, steroid hormones, and more.
Learn more about CholesterolPolyglyceryl-10 Laurate is an ester of lauric acid and Polyglycerin-10.
Polyglyceryl-10 Laurate is a cleansing agent and emulsifier. It helps gather dirt, oil, and other pollutants to be rinsed away. As an emulsifier, it helps prevent ingredients from separating, such as oil and water.
Polyglyceryl-10 Laurate may not be fungal acne safe.
Learn more about Polyglyceryl-10 LaurateWe don't have a description for Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate yet.
Methyl Di-T-Butyl Hydroxyhydrocinnamate is an antioxidant and is a fragrance.
Potassium Cetyl Phosphate is the potassium salt of a mixture. This mixture consists of the esters from phosphoricacid and cetyl alcohol.
Potassium Cetyl Phosphate is an emulsifier and cleansing agent. Emulsifiers help stabilize a product. It does this by preventing certain ingredients from separating.
As a cleansing agent, Potassium Cetyl Phosphate helps gather oils, dirts, and pollutants from your skin. This makes it easier to rinse them away with water.
Learn more about Potassium Cetyl PhosphateWe don't have a description for Tris(Tetramethylhydroxypiperidinol) Citrate yet.
Glyceryl Citrate/Lactate/Linoleate/Oleate isn't fungal acne safe.
Aluminum Starch Octenylsuccinate is a synthetic powder used as an absorbent, thickener, and anti-caking agent.
As an absorbent, it is great at mattifying skin by soaking up the oil. This is why you'll find it in a range of products from makeup to moisturizers.
This ingredient is considered a modified starch. Starch can also be found naturally in plants.
One study from 1991 found that 5% of this ingredient enhanced titanium dioxide SPF by as much as 40%. The study found 1% titanium dioxide had a 5.6 SPF and adding 5% of aluminum starch octenylsuccinate boosted it to an SPF of 8.1
Although “aluminum” in an ingredient name can raise red flags for some consumers, the form and usage context matter significantly. For typical topical applications, there is no substantial evidence of health risks - such as cancer, neurotoxicity, or systemic “aluminum overload.”
Learn more about Aluminum Starch OctenylsuccinateGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinRetinal is a form of retinoid. Retinoids are the gold-standard class of anti-aging ingredients.
Retinal has many benefits as other retinoids: improve skin texture, reduce large pores, reduce the effects of aging, reduce the visibility of dark spots, heal scars, and fight acne.
Studies show retinal may work at a faster rate than retinol due to its structure.
All retinoids have to be converted into retinoic acid before starting to work. Some retinoids take several steps of conversion before binding. Retinal is only one step away, making it more potent.
Like other retinoids, retinal may be irritating. It is best to ease into using this ingredient frequently.
Using the 'ramp up' method, start by using retinol once a week. This gives your skin time to adjust and decrease irritation. Once you feel ready, you can slowly increase the frequency of retinol use.
Using retinoids will increase sun-sensitivity in the first few weeks of use. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.
Learn more about RetinalSqualane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.
Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.
Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.
Research shows that squalane is non-irritating (even at 100% concentration).
In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.
The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.
Is squalane vegan?
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Is squalane an oil?
Squalane is often called an oil, but it’s technically not; it’s a hydrocarbon, meaning it’s only made of carbon and hydrogen, unlike true oils which are triglycerides made of fatty acids and glycerol.
The term “oil-free” isn’t regulated, so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
While some people avoid oils thinking they cause breakouts, the right kind of oil (or oil-like ingredient like squalane) can actually help balance and hydrate your skin. It’s worth testing out simple oils or squalane to see what works best for your skin.
Learn more about SqualaneWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterWe don't have a description for Polyquaternium-6 yet.
Sodium Hyaluronate Crosspolymer is a type of hyaluronic acid. In fact, it is modified version of hyaluronic acid.
The structure of Sodium Hyaluronate Crosspolymer allows it to stay in the skin's top layer for a longer period of time. This allows for even more hydration and humectant action than hyaluronic acid.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium Hyaluronate CrosspolymerCatnip has antioxidant and antimicrobial properties.
Fun fact: This plant is called "cataria" or "catnip" because 2/3 of all cats are attracted to this plant.
We don't have a description for Caprylyl Glucoside yet.
Camellia Japonica Flower Extract comes from the Japanese Camellia plant. This plant is native to East Asia and known as "Tsubaki" in Japanese.
Tsubaki flowers possess antioxidant and soothing properties. This flower has shown to be effective at fighting pollution damage by protecting your skin's fibroblasts. Your skin's fibroblasts help create collagen and collagen is responsible for youthful, plump skin.
This flower also contains many antioxidant enzymes. Antioxidants help fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. They may originate from sunlight, air pollution, or cigarette smoke. These free-radical molecules are unstable and are often looking for missing electrons. This instability causes free-radicals to damage our cells. Antioxidants help stabilize free-radicals by donating extra electrons.
Thus, Camellia Japonica Flower Extract may help reduce the signs of aging.
Learn more about Camellia Japonica Flower ExtractPolyglyceryl-10 Oleate isn't fungal acne safe.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolAcetyl Hexapeptide-8 is a peptide. A common name for this peptide is Argireline.
Argireline has a similar function to botox; it prevents muscle movement and contractions slightly. By preventing muscles from moving, argireline also prohibits the formation of fine lines and wrinkles. However, research is lacking in proving this ingredient to be as effective as botox.
On the other hand, argireline tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Read more about other common types of peptides here:
Learn more about Acetyl Hexapeptide-8Acetyl Tetrapeptide-9 is a signal peptide. Signal peptides tell your skin to create collagen or start tissue repair.
This peptide plays a role in key skin components such as collagen, lumican, and glycosaminoglycans (GAGs). Lumican is used in collagen organization and regulation, while GAGs are a component that holds water in our skin.
The manufacturer claims this ingredient is effective at firming the skin and enhancing skin hydration.
Learn more about Acetyl Tetrapeptide-9Adenosine is in every living organism. It is one of four components in nucleic acids that helps store our DNA.
Adenosine has many benefits when used. These benefits include hydrating the skin, smoothing skin, and reducing wrinkles. Once applied, adenosine increases collagen production. It also helps with improving firmness and tissue repair.
Studies have found adenosine may also help with wound healing.
In skincare products, Adenosine is usually derived from yeast.
Learn more about AdenosineCarnosine is a dipeptide made from two amino acids.
This ingredient helps:
Glycation is the process of sugars binding to and damaging proteins. Too much sugar in our skin can lead to damaged collagen, contributing to factors of aging.
Carnosine is water-soluble and is not able to travel deeper layers of skin. This leads to some doubt about whether it can boost collagen in skin, since collagen is located in the deeper layers of skin.
Fun fact: Carnosine can be naturally found in our muscles and brain.
Learn more about CarnosinePalmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.
This ingredient consists of four amino acids and palmitic acid. These amino acids are arginine, proline, glutamine, and glycine.
This ingredient has many benefits. These benefits include boosting collagen production, fighting inflammation, and reversing UV damage.
By preventing our bodies from producing interleukins, Palmitoyl Tetrapeptide-7 helps fight inflammation. An interleukin is a chemical that signals to the body to produce an inflammatory response. Interleukin production is accelerated by UV radiation.
Palmitoyl Tetrapeptide-7 tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tetrapeptide-7Ascorbic Acid is is pure Vitamin C. This form makes up the largest amount of vitamin C found naturally in our skin.
Not only is vitamin C great for your overall health and immune system, it also has plenty of benefits on your skin.
Vitamin C is best used for brightening skin. It improves dark spots, acne scars, and hyperpigmentation. This is because it blocks the process of skin darkening when exposed to UV.
Remember: Vitamin C should not replace sunscreen!
Your skin uses vitamin C to build collagen. Collagen is one key component in having a strong skin barrier and plump skin. Vitamin C also plays a role in regulating collagen, thus making it effective in improving wrinkles and fine lines.
Ascorbic acid shows potent antioxidant activity. As an antioxidant, it helps fight free-radicals. Free-radicals are molecules that may damage your skin cells. These antioxidants also protect skin against UV damage.
The best formulations include Vitamin E and/or ferulic acid. These two ingredients help stabilize and provide a boost in the benefits of ascorbic acid. This is because ascorbic acid becomes unstable when exposed to UV and air. In fact, you can tell your ascorbic acid has oxidized when it turns an orange-yellow color.
Ascorbic acid is generally compatible with other ingredients. However, using ascorbic acid with other active ingredients might cause irritation. Two ingredients: copper ions and benzoyl peroxide, will inactivate ascorbic acid completely.
Read more about other types of Vitamin C:
Foods rich with vitamin C include oranges, strawberries, broccoli, bell peppers, and more. When consuming Vitamin C, your skin receives a portion of the nutrients.
Learn more about Ascorbic AcidReviews
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Where it's from
MediCube is a Korean brand
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Published May 13, 2025 • Added by tygerrrecchia