Versus

MediCube Retinol-Some 1.9% NMN Boosting Serum Versus The Ordinary Retinol 0.5% in Squalane

Serum
Serum
Korean Brand
Canadian Brand

Updated on May 19, 2025

Overview

What they are

These products are both cruelty-free and reef safe serums. They have a total of 3 ingredients in common

Cool Features

They both contain retinoid

Suited For

They're both likely to be good for fighting acne, anti aging, dry skin, brightening skin, oily skin, reducing pores, scar healing, dark spots and better texture

Free From

They both do not contain any harsh alcohols, common allergens, fragrances, parabens, silicones or sulfates

What's Inside

They both contain oils

We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.

Ingredient Info

Click any item below to learn more and see relevant ingredients

What's inside (and what isn't)

What's inside (and what isn't)

At a glance

Click on any of the items below to learn more

Key Ingredients

Benefits

Concerns

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

found in both products
Retinol-Some 1.9% NMN Boosting Serum

Water

Skin Conditioning

Glycereth-26

Humectant
0 / 0 Helps hydrate Dry Skin Icon

Niacinamide

Smoothing
Niacinamide IconGood for Oily Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin Icon

Glycerin

Humectant
0 / 0 Helps hydrate Dry Skin IconGood for Scar Healing IconHelps brighten skin Icon

Caprylic/Capric Triglyceride

Masking
Helps hydrate Dry Skin Icon

Macadamia Ternifolia Seed Oil

Emollient
Oil IconNot safe for Fungal Acne Icon

Butylene Glycol

Humectant
1 / 0 Helps hydrate Dry Skin Icon

Hydrogenated Lecithin

Emulsifying
Helps hydrate Dry Skin Icon

Retinol

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Brassica Campestris Sterols

Emollient
Not safe for Fungal Acne Icon

1,2-Hexanediol

Skin Conditioning
Helps hydrate Dry Skin Icon

Cholesterol

Emollient
0 / 0 Helps hydrate Dry Skin Icon

Polyglyceryl-10 Laurate

Skin Conditioning
Not safe for Fungal Acne Icon

Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate

Skin Conditioning

Aluminum/Magnesium Hydroxide Stearate

Emulsion Stabilising

Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate

Antioxidant
Antioxidant Icon

Potassium Cetyl Phosphate

Emulsifying

Tris(Tetramethylhydroxypiperidinol)Citrate

Stabilising

Glyceryl Citrate/Lactate/Linoleate/Oleate

Emulsifying
Not safe for Fungal Acne Icon

Elaeis Guineensis Oil

Emollient
Oil IconHelps hydrate Dry Skin IconNot safe for Fungal Acne Icon

Cetyl Ethylhexanoate

Emollient

Hydroxyacetophenone

Antioxidant
Antioxidant IconHelps reduce irritation Icon

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Polyacrylate Crosspolymer-6

Emulsion Stabilising

Aluminum Starch Octenylsuccinate

Absorbent
Good for Oily Skin Icon

Retinal

Skin Conditioning
Retinoid IconGood for Oily Skin IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps fight Acne IconHelps brighten skin IconMay worsen Rosacea Icon

Squalane

Emollient
1 / 0 Helps hydrate Dry Skin Icon

Polyquaternium-51

Skin Conditioning
Helps hydrate Dry Skin Icon

Tocopherol

Antioxidant
0-3 / 0-3 Vitamin E IconAntioxidant IconHelps hydrate Dry Skin IconHelps with Anti-Aging IconGood for Scar Healing Icon

Panthenol

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Allantoin

Skin Conditioning
0 / 0 Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Adenosine

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Scar Healing Icon

Disodium EDTA

Bifida Ferment Lysate

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce irritation Icon

Lactobacillus Ferment Lysate

Skin Conditioning
Not safe for Fungal Acne Icon

Lactococcus Ferment Lysate

Skin Conditioning

Dipropylene Glycol

Masking

Centella Asiatica Leaf Extract

Skin Conditioning
Helps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging Icon

Asiaticoside

Antioxidant
Antioxidant IconHelps reduce Skin Redness IconHelps reduce irritation IconGood for Scar Healing Icon

Asiatic Acid

Skin Conditioning

Madecassic Acid

Skin Conditioning
Helps reduce irritation IconHelps with Anti-Aging Icon

Beta-Glucan

Skin Conditioning
Helps hydrate Dry Skin IconHelps reduce Skin Redness IconHelps reduce irritation IconHelps with Anti-Aging IconGood for Scar Healing Icon

Ceramide NP

Skin Conditioning
Ceramide IconHelps hydrate Dry Skin IconHelps reduce irritation IconHelps with Anti-Aging Icon

Propanediol

Solvent
Helps hydrate Dry Skin Icon

Eriobotrya Japonica Leaf Extract

Skin Conditioning

Mentha Viridis Extract

Masking

Sodium Hyaluronate Crosspolymer

Humectant
Hyaluronic Acid IconHelps hydrate Dry Skin IconGood for Scar Healing Icon

Pentylene Glycol

Skin Conditioning

Ethylhexylglycerin

Skin Conditioning

Nicotinamide Mononucleotide

Antioxidant
Antioxidant Icon

Akebia Quinata Extract

Skin Conditioning

Caprylyl/Capryl Glucoside

Cleansing

Camellia Japonica Flower Extract

Emollient

Polyglyceryl-10 Oleate

Skin Conditioning
Not safe for Fungal Acne Icon

Acetyl Hexapeptide-8

Humectant
Peptide IconHelps hydrate Dry Skin IconHelps with Anti-Aging Icon

Acetyl Tetrapeptide-5

Humectant
Peptide Icon

Carnosine

Skin Conditioning
Helps with Anti-Aging IconGood for Scar Healing Icon

Palmitoyl Tetrapeptide-7

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Palmitoyl Tripeptide-5

Skin Conditioning
Peptide IconHelps with Anti-Aging IconNot safe for Fungal Acne Icon

Yeast Beta-Glucan

Skin Conditioning

Ferulic Acid

Antimicrobial
Antioxidant IconHelps with Anti-Aging IconGood for Dark Spots Icon

3-O-Ethyl Ascorbic Acid

Skin Conditioning
Vitamin C IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores Icon

Ascorbic Acid

Antioxidant
Vitamin C IconAntioxidant IconHelps reduce Skin Redness IconGood for Skin Texture IconGood for Minimizing Pores IconHelps with Anti-Aging IconGood for Dark Spots IconGood for Scar Healing IconHelps brighten skin Icon

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Masking, Skin Conditioning

This ingredient is an emollient, solvent, and texture enhancer. It is considered a skin-softener by helping the skin prevent moisture loss.

It helps thicken a product's formula and makes it easier to spread by dissolving clumping compounds.

Caprylic Triglyceride is made by combining glycerin with coconut oil, forming a clear liquid.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this.

Learn more about Caprylic/Capric Triglyceride
Skin Conditioning

Retinol is a gold-standard ingredient for anti-aging. It is a form of Vitamin A and belongs to the class of retinoids that also includes tretinoin.

Why is retinol famous?

It has the most scientific studies backing up its skin benefits out of all the non-prescription ingredients.

Retinol is proven to:

This is why retinol is effective at removing wrinkles, fading dark spots, treating acne, and reducing the appearance of pores.

Studies show retinol is less effective when exposed to UV. Be sure to look for appropriate packaging to keep your retinol potent (similar to Vitamin C).

Using retinol or any retinoids will increase sun-sensitivity in the first few months. Though studies show retinoids increase your skin's natural SPF with continuous use, it is best to always wear sunscreen and sun-protection.

We recommend speaking with a medical professional about using this ingredient during pregnancy.

Retinol may cause irritation in some people, so be sure to patch test. Experts recommend 'ramping up' retinol use: start using this ingredient once a week and work up to using it daily.

Read about Tretinoin

Learn more about Retinol
Emollient, Skin Conditioning

Squalane is an emollient that helps the skin hold onto moisture. It's an oily liquid that occurs naturally in certain types of fish and plant oils.

Because squalane boosts hydration in the skin, it also comes with plenty of benefits: it is an antioxidant and can help fight free radicals and skin damage. Squalane is also found to have a detoxifying effect when applied.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan?

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Is squalane an oil?

Squalane is often called an oil, but it’s technically not; it’s a hydrocarbon, meaning it’s only made of carbon and hydrogen, unlike true oils which are triglycerides made of fatty acids and glycerol.

The term “oil-free” isn’t regulated, so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

While some people avoid oils thinking they cause breakouts, the right kind of oil (or oil-like ingredient like squalane) can actually help balance and hydrate your skin. It’s worth testing out simple oils or squalane to see what works best for your skin.

Learn more about Squalane

When to use

4 Routines
0% use in am
100% use in pm
75% use every day
821 Routines
6% use in am
94% use in pm
68% use every day
When to use See routines that use it ->

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