Skinfix Barrier+ Triple Lipid + Collagen + Niacinamide Activating Serum Versus Naturium Multi-Peptide Advanced Serum
This barrier-repair serum is formulated around Niacinamide and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles.
This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Ferulic Acid to soften the look of wrinkles.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningCaprylyl Caprylate/Caprate
EmollientPropanediol
SolventJojoba Oil/Macadamia Seed Oil Esters
Skin ConditioningNiacinamide
SmoothingGlycerin
HumectantAmmonium Acryloyldimethyltaurate/Vp Copolymer
Squalene
EmollientMacadamia Integrifolia Seed Oil
Skin ConditioningAmylopectin
Lecithin
EmollientPhytosteryl Macadamiate
Skin ConditioningCollagen Amino Acids
MoisturisingLithothamnion Calcareum Extract
Skin ConditioningSodium Hyaluronate
HumectantOligopeptide-3
Skin ConditioningOligopeptide-2
Skin ConditioningOligopeptide-1
Skin ConditioningHexapeptide-11
Skin ConditioningFolic Acid
Skin ConditioningBacillus/Soybean Ferment Extract
Skin ConditioningLactic Acid
BufferingPhospholipids
Skin ConditioningCeramide NP
Skin ConditioningPhytosterols
Skin ConditioningPhytosphingosine
Skin ConditioningCeramide AP
Skin ConditioningCholesterol
EmollientMyrica Cerifera Fruit Extract
HumectantAkebia Quinata Stem Extract
Skin ConditioningPrunus Lannesiana Flower Extract
Skin ConditioningSaccharomyces Lysate
Skin ConditioningLactobacillus Ferment Lysate
Skin ConditioningTripeptide-1
Skin ConditioningCeramide EOP
Skin ConditioningPolyglutamic Acid
Skin ConditioningTocopheryl Acetate
AntioxidantTocopherol
AntioxidantButylene Glycol
HumectantCaprylyl Glycol
EmollientSodium Lauroyl Lactylate
EmulsifyingEthylhexylglycerin
Skin ConditioningHexylene Glycol
EmulsifyingPentylene Glycol
Skin ConditioningAcetyl Glutamine
Skin ConditioningTrisodium Ethylenediamine Disuccinate
Leuconostoc/Radish Root Ferment Filtrate
AntimicrobialSodium Benzoate
MaskingHydroxyacetophenone
AntioxidantXanthan Gum
EmulsifyingPotassium Sorbate
PreservativeCarbomer
Emulsion Stabilising1,2-Hexanediol
Skin ConditioningDextran
Phenoxyethanol
PreservativeWater, Caprylyl Caprylate/Caprate, Propanediol, Jojoba Oil/Macadamia Seed Oil Esters, Niacinamide, Glycerin, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Squalene, Macadamia Integrifolia Seed Oil, Amylopectin, Lecithin, Phytosteryl Macadamiate, Collagen Amino Acids, Lithothamnion Calcareum Extract, Sodium Hyaluronate, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11, Folic Acid, Bacillus/Soybean Ferment Extract, Lactic Acid, Phospholipids, Ceramide NP, Phytosterols, Phytosphingosine, Ceramide AP, Cholesterol, Myrica Cerifera Fruit Extract, Akebia Quinata Stem Extract, Prunus Lannesiana Flower Extract, Saccharomyces Lysate, Lactobacillus Ferment Lysate, Tripeptide-1, Ceramide EOP, Polyglutamic Acid, Tocopheryl Acetate, Tocopherol, Butylene Glycol, Caprylyl Glycol, Sodium Lauroyl Lactylate, Ethylhexylglycerin, Hexylene Glycol, Pentylene Glycol, Acetyl Glutamine, Trisodium Ethylenediamine Disuccinate, Leuconostoc/Radish Root Ferment Filtrate, Sodium Benzoate, Hydroxyacetophenone, Xanthan Gum, Potassium Sorbate, Carbomer, 1,2-Hexanediol, Dextran, Phenoxyethanol
Water
Skin ConditioningPropanediol
SolventCaprylic/Capric Triglyceride
MaskingIsopentyldiol
HumectantEthylhexyl Polyhydroxystearate
EmollientSqualane
EmollientTetradecane
PerfumingGlyceryl Stearate Citrate
EmollientButyrospermum Parkii Butter
Skin ConditioningPolyglyceryl-3 Stearate
EmulsifyingHelianthus Annuus Extract
EmollientOryza Sativa Bran Extract
Skin ConditioningMannitol
HumectantPhosphatidylcholine
EmulsifyingFerulic Acid
AntimicrobialArginine
MaskingAcetyl Hexapeptide-8
HumectantCopper Palmitoyl Heptapeptide-14
Skin ConditioningPalmitoyl Sh-Heptapeptide-12 Sp
Skin ConditioningHydrolyzed Collagen
EmollientRosmarinus Officinalis Leaf Extract
AntimicrobialLactic Acid/Glycolic Acid Copolymer
Skin ConditioningGlycerin
HumectantTocopherol
AntioxidantPullulan
Lysolecithin
EmulsifyingSclerotium Gum
Emulsion StabilisingHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingDimethicone
EmollientSodium Phytate
ChelatingDiglycerin
HumectantHydrogenated Lecithin
EmulsifyingSilica
AbrasiveCetyl Alcohol
EmollientHydroxyacetophenone
AntioxidantPolysorbate 60
EmulsifyingSorbitan Isostearate
EmulsifyingSodium Hydroxide
BufferingSodium Benzoate
MaskingPotassium Sorbate
PreservativePolyvinyl Alcohol
Decyl Glucoside
CleansingXanthan Gum
EmulsifyingTocopheryl Acetate
AntioxidantSodium Chloride
MaskingCitric Acid
BufferingPhenoxyethanol
PreservativeWater, Propanediol, Caprylic/Capric Triglyceride, Isopentyldiol, Ethylhexyl Polyhydroxystearate, Squalane, Tetradecane, Glyceryl Stearate Citrate, Butyrospermum Parkii Butter, Polyglyceryl-3 Stearate, Helianthus Annuus Extract, Oryza Sativa Bran Extract, Mannitol, Phosphatidylcholine, Ferulic Acid, Arginine, Acetyl Hexapeptide-8, Copper Palmitoyl Heptapeptide-14, Palmitoyl Sh-Heptapeptide-12 Sp, Hydrolyzed Collagen, Rosmarinus Officinalis Leaf Extract, Lactic Acid/Glycolic Acid Copolymer, Glycerin, Tocopherol, Pullulan, Lysolecithin, Sclerotium Gum, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Dimethicone, Sodium Phytate, Diglycerin, Hydrogenated Lecithin, Silica, Cetyl Alcohol, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Sodium Hydroxide, Sodium Benzoate, Potassium Sorbate, Polyvinyl Alcohol, Decyl Glucoside, Xanthan Gum, Tocopheryl Acetate, Sodium Chloride, Citric Acid, Phenoxyethanol
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinHydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster.
As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress.
Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol.
This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency.
You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase.
Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well.
An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient.
So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced.
Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable.
Learn more about HydroxyacetophenonePhenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Learn more about PhenoxyethanolPotassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Learn more about Potassium SorbatePropanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolSodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.
Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.
Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.
It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.
Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.
We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.
Learn more about Sodium BenzoateTocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolTocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Learn more about Tocopheryl AcetateWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan Gum