This anti-aging ampoule is formulated around Copper Tripeptide-1 to soften the look of wrinkles and strengthen the skin barrier.
This anti-aging serum is formulated around Niacinamide and Adenosine to soften the look of wrinkles and strengthen the skin barrier.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningDicaprylyl Ether
EmollientButylene Glycol
HumectantCoco-Caprylate/Caprate
EmollientGlycerin
HumectantPentaerythrityl Tetraisostearate
EmollientDicaprylyl Carbonate
Emollient1,2-Hexanediol
Skin ConditioningCaprylic/Capric Triglyceride
MaskingDiisostearoyl Polyglyceryl-3 Dimer Dilinoleate
EmollientHydrolyzed Rice Protein
Skin ConditioningGlycine Soja Protein
EmulsifyingAcetyl Sh-Hexapeptide-5 Amide Acetate
Skin ConditioningCentella Asiatica Leaf Extract
Skin ConditioningLinoleic Acid
CleansingLinolenic Acid
CleansingSwertia Chirata Extract
HumectantGlycine
BufferingSerine
MaskingGlutamic Acid
HumectantLeucine
Skin ConditioningAlanine
MaskingLysine
Skin ConditioningArginine
MaskingTyrosine
MaskingHexapeptide-9
Skin ConditioningAcetyl Tetrapeptide-5
HumectantAcetyl Tetrapeptide-2
Skin ConditioningPalmitoyl Pentapeptide-4
Skin ConditioningTripeptide-1
Skin ConditioningHexapeptide-11
Skin ConditioningAcetyl Hexapeptide-8
HumectantCopper Tripeptide-1
Skin ConditioningAlanine/Histidine/Lysine Polypeptide Copper Hcl
Skin ConditioningArgania Spinosa Kernel Oil
EmollientTripeptide-32
Skin ConditioningPalmitoyl Tetrapeptide-7
Skin ConditioningScutellaria Baicalensis Root Extract
AstringentPolygonum Multiflorum Root Extract
Skin ConditioningSophora Flavescens Root Extract
AntioxidantCimicifuga Racemosa Root Extract
AntimicrobialPhenylalanine
MaskingValine
MaskingProline
Skin ConditioningThreonine
Aspartic Acid
MaskingIsoleucine
Skin ConditioningHistidine
HumectantMethionine
Skin ConditioningCysteine
AntioxidantDextrin Palmitate
EmulsifyingSuperoxide Dismutase
AntioxidantGlycyrrhiza Glabra Root Extract
BleachingAngelica Gigas Root Extract
Skin ConditioningAdenosine
Skin ConditioningMorus Alba Bark Extract
Skin ConditioningPhellinus Linteus Extract
Skin ConditioningDioscorea Opposita Root Extract
Skin ConditioningPaeonia Albiflora Root Extract
Skin ConditioningSesamum Indicum Seed Extract
Skin ConditioningSodium Dextran Sulfate
Gel FormingPolyglyceryl-4 Oleate
EmulsifyingDisteardimonium Hectorite
StabilisingPolyglyceryl-6 Oleate
EmulsifyingPolyhydroxystearic Acid
EmulsifyingPropylene Carbonate
SolventCellulose Gum
Emulsion StabilisingPolyglyceryl-10 Laurate
Skin ConditioningEthylhexylglycerin
Skin ConditioningTocopherol
AntioxidantSodium Phytate
Caprylyl Glycol
EmollientPentylene Glycol
Skin ConditioningSodium Benzoate
MaskingMaltodextrin
AbsorbentSodium Chloride
MaskingWater, Dicaprylyl Ether, Butylene Glycol, Coco-Caprylate/Caprate, Glycerin, Pentaerythrityl Tetraisostearate, Dicaprylyl Carbonate, 1,2-Hexanediol, Caprylic/Capric Triglyceride, Diisostearoyl Polyglyceryl-3 Dimer Dilinoleate, Hydrolyzed Rice Protein, Glycine Soja Protein, Acetyl Sh-Hexapeptide-5 Amide Acetate, Centella Asiatica Leaf Extract, Linoleic Acid, Linolenic Acid, Swertia Chirata Extract, Glycine, Serine, Glutamic Acid, Leucine, Alanine, Lysine, Arginine, Tyrosine, Hexapeptide-9, Acetyl Tetrapeptide-5, Acetyl Tetrapeptide-2, Palmitoyl Pentapeptide-4, Tripeptide-1, Hexapeptide-11, Acetyl Hexapeptide-8, Copper Tripeptide-1, Alanine/Histidine/Lysine Polypeptide Copper Hcl, Argania Spinosa Kernel Oil, Tripeptide-32, Palmitoyl Tetrapeptide-7, Scutellaria Baicalensis Root Extract, Polygonum Multiflorum Root Extract, Sophora Flavescens Root Extract, Cimicifuga Racemosa Root Extract, Phenylalanine, Valine, Proline, Threonine, Aspartic Acid, Isoleucine, Histidine, Methionine, Cysteine, Dextrin Palmitate, Superoxide Dismutase, Glycyrrhiza Glabra Root Extract, Angelica Gigas Root Extract, Adenosine, Morus Alba Bark Extract, Phellinus Linteus Extract, Dioscorea Opposita Root Extract, Paeonia Albiflora Root Extract, Sesamum Indicum Seed Extract, Sodium Dextran Sulfate, Polyglyceryl-4 Oleate, Disteardimonium Hectorite, Polyglyceryl-6 Oleate, Polyhydroxystearic Acid, Propylene Carbonate, Cellulose Gum, Polyglyceryl-10 Laurate, Ethylhexylglycerin, Tocopherol, Sodium Phytate, Caprylyl Glycol, Pentylene Glycol, Sodium Benzoate, Maltodextrin, Sodium Chloride
Water
Skin ConditioningPropanediol
SolventGlycerin
HumectantMethylpropanediol
SolventIsononyl Isononanoate
EmollientNiacinamide
Smoothing1,2-Hexanediol
Skin ConditioningPolyglycerin-3
HumectantCaprylic/Capric Triglyceride
MaskingTriethylhexanoin
MaskingButylene Glycol
HumectantTriolein
Skin ConditioningAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingTromethamine
BufferingHydrogenated Poly(C6-20 Olefin)
AbrasiveCarbomer
Emulsion StabilisingEthylhexylglycerin
Skin ConditioningPentylene Glycol
Skin ConditioningTocopherol
AntioxidantAdenosine
Skin ConditioningHdi/Trimethylol Hexyllactone Crosspolymer
Ascorbyl Tetraisopalmitate
AntioxidantSodium Metaphosphate
BufferingParfum
MaskingBeta-Glucan
Skin ConditioningPrunus Armeniaca Kernel Oil
MaskingXanthan Gum
EmulsifyingLinalool
PerfumingAchillea Millefolium Extract
CleansingCamellia Japonica Seed Extract
Skin ConditioningGeraniol
PerfumingFerulic Acid
AntimicrobialCaprylyl Glycol
EmollientPaeonia Albiflora Root Extract
Skin ConditioningCI 15985
Cosmetic ColorantCI 17200
Cosmetic ColorantSoluble Collagen
HumectantVegetable Oil
Skin ConditioningAcetyl Heptapeptide-4
HumectantPaeonia Albiflora Flower Extract
TonicAcetyl Hexapeptide-8
HumectantSodium Hydroxide
BufferingAcetyl Tetrapeptide-2
Skin ConditioningAcetyl Octapeptide-3
HumectantWater, Propanediol, Glycerin, Methylpropanediol, Isononyl Isononanoate, Niacinamide, 1,2-Hexanediol, Polyglycerin-3, Caprylic/Capric Triglyceride, Triethylhexanoin, Butylene Glycol, Triolein, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Hydrogenated Poly(C6-20 Olefin), Carbomer, Ethylhexylglycerin, Pentylene Glycol, Tocopherol, Adenosine, Hdi/Trimethylol Hexyllactone Crosspolymer, Ascorbyl Tetraisopalmitate, Sodium Metaphosphate, Parfum, Beta-Glucan, Prunus Armeniaca Kernel Oil, Xanthan Gum, Linalool, Achillea Millefolium Extract, Camellia Japonica Seed Extract, Geraniol, Ferulic Acid, Caprylyl Glycol, Paeonia Albiflora Root Extract, CI 15985, CI 17200, Soluble Collagen, Vegetable Oil, Acetyl Heptapeptide-4, Paeonia Albiflora Flower Extract, Acetyl Hexapeptide-8, Sodium Hydroxide, Acetyl Tetrapeptide-2, Acetyl Octapeptide-3
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Learn more about Acetyl Hexapeptide-8This peptide is more commonly known as Thymulen 4 BG.
It is derived from a youth hormone called thymopoietin. Thymopoietin helps regulate the immune system and decreases naturally with age.
According to the manufacturer, this peptide boosts the skin's immune defenses and regenerates the outer layers of skin.
Learn more about Acetyl Tetrapeptide-2Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCaprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinThis ingredient comes from the root of Paeonia albiflora, aka as Radix Paeoniae Alba or the Chinese peony. It has skin conditioning properties and is rich in antioxidant compounds.
Recent research shows Paeonia Albiflora root extract helps slow down glycation. Glycation is a process where sugars damage skin proteins and contribute to dullness/uneven skin tone.
In human studies, a lotion with 1% Paeonia Albiflora Root Extract led to lower melanin levels and fewer visible dark spots after two weeks of use. In vitro and ex vivo studies support its role in regulating the process of pigment production and reducing inflammation in skin cells.
Additionally, this ingredient has been shown to promote keratinocyte migration and proliferation in wound healing models.
Paeonia Albiflora root extract is water-soluble and has a low irritation profile for most skin types. Like other botanical extracts, patch testing is recommended for people who have known plant allergies or reactive skin.
Learn more about Paeonia Albiflora Root ExtractPentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolTocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water