This anti-aging serum is formulated around Copper Tripeptide-1 and Acetyl Hexapeptide-8 to soften the look of wrinkles.
This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Ferulic Acid to soften the look of wrinkles.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningDipropylene Glycol
HumectantGlycerin
Humectant1,2-Hexanediol
Skin ConditioningBetaine
HumectantCopper Tripeptide-1
Skin ConditioningAcetyl Hexapeptide-8
HumectantPalmitoyl Tripeptide-1
Skin ConditioningTetrapeptide-21
Skin ConditioningTetrapeptide-30
Skin ConditioningHeptasodium Hexacarboxymethyl Dipeptide-12
Skin ConditioningAcetyl Tetrapeptide-5
HumectantPalmitoyl Tripeptide-38
Skin ConditioningPalmitoyl Pentapeptide-4
Skin ConditioningDipeptide-2
Skin ConditioningTripeptide-1
Skin ConditioningHexapeptide-9
Skin ConditioningNonapeptide-1
Skin ConditioningCollagen Extract
Skin ConditioningSerine
MaskingMethionine
Skin ConditioningCysteine
AntioxidantArginine
MaskingAcmella Oleracea Extract
Skin ProtectingAlpha-Glucan Oligosaccharide
CleansingSodium PCA
HumectantUlmus Davidiana Root Extract
Skin ConditioningCichorium Intybus Root Extract
MaskingHelianthus Tuberosus Root Extract
Skin ConditioningTremella Fuciformis Extract
HumectantFomes Officinalis Extract
Skin ProtectingLentinus Edodes Extract
Skin ConditioningPyrus Malus Fruit Extract
Skin ConditioningLens Esculenta Fruit Extract
Skin ConditioningCitrullus Lanatus Fruit Extract
Skin ConditioningSodium Acetylated Hyaluronate
HumectantHydrolyzed Hyaluronic Acid
HumectantHyaluronic Acid
HumectantSodium Hyaluronate
HumectantSodium Hyaluronate Crosspolymer
HumectantPotassium Hyaluronate
Skin ConditioningSqualane
EmollientFicus Carica Fruit Extract
HumectantCynanchum Atratum Extract
Skin ConditioningHydroxypropyltrimonium Hyaluronate
Ocimum Sanctum Leaf Extract
Skin ConditioningMelia Azadirachta Leaf Extract
Skin ConditioningCurcuma Longa Root Extract
AntioxidantCorallina Officinalis Extract
Skin ConditioningSolanum Melongena Fruit Extract
Skin ConditioningCoccinia Indica Fruit Extract
Skin ConditioningGellan Gum
Butylene Glycol
HumectantAdenosine
Skin ConditioningAloe Barbadensis Flower Extract
EmollientMelia Azadirachta Flower Extract
Skin ConditioningPolyglyceryl-10 Eicosanedioate/Tetradecanedioate
Skin ConditioningPolyquaternium-51
Skin ConditioningSodium Polyacryloyldimethyl Taurate
Emulsion StabilisingHydroxypropyl Cyclodextrin
MaskingEthylhexylglycerin
Skin ConditioningHydroxyethylcellulose
Emulsion StabilisingCaprylyl Glycol
EmollientWater, Dipropylene Glycol, Glycerin, 1,2-Hexanediol, Betaine, Copper Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Tetrapeptide-21, Tetrapeptide-30, Heptasodium Hexacarboxymethyl Dipeptide-12, Acetyl Tetrapeptide-5, Palmitoyl Tripeptide-38, Palmitoyl Pentapeptide-4, Dipeptide-2, Tripeptide-1, Hexapeptide-9, Nonapeptide-1, Collagen Extract, Serine, Methionine, Cysteine, Arginine, Acmella Oleracea Extract, Alpha-Glucan Oligosaccharide, Sodium PCA, Ulmus Davidiana Root Extract, Cichorium Intybus Root Extract, Helianthus Tuberosus Root Extract, Tremella Fuciformis Extract, Fomes Officinalis Extract, Lentinus Edodes Extract, Pyrus Malus Fruit Extract, Lens Esculenta Fruit Extract, Citrullus Lanatus Fruit Extract, Sodium Acetylated Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Potassium Hyaluronate, Squalane, Ficus Carica Fruit Extract, Cynanchum Atratum Extract, Hydroxypropyltrimonium Hyaluronate, Ocimum Sanctum Leaf Extract, Melia Azadirachta Leaf Extract, Curcuma Longa Root Extract, Corallina Officinalis Extract, Solanum Melongena Fruit Extract, Coccinia Indica Fruit Extract, Gellan Gum, Butylene Glycol, Adenosine, Aloe Barbadensis Flower Extract, Melia Azadirachta Flower Extract, Polyglyceryl-10 Eicosanedioate/Tetradecanedioate, Polyquaternium-51, Sodium Polyacryloyldimethyl Taurate, Hydroxypropyl Cyclodextrin, Ethylhexylglycerin, Hydroxyethylcellulose, Caprylyl Glycol
Water
Skin ConditioningPropanediol
SolventCaprylic/Capric Triglyceride
MaskingIsopentyldiol
HumectantEthylhexyl Polyhydroxystearate
EmollientSqualane
EmollientTetradecane
PerfumingGlyceryl Stearate Citrate
EmollientButyrospermum Parkii Butter
Skin ConditioningPolyglyceryl-3 Stearate
EmulsifyingHelianthus Annuus Extract
EmollientOryza Sativa Bran Extract
Skin ConditioningMannitol
HumectantPhosphatidylcholine
EmulsifyingFerulic Acid
AntimicrobialArginine
MaskingAcetyl Hexapeptide-8
HumectantCopper Palmitoyl Heptapeptide-14
Skin ConditioningPalmitoyl Sh-Heptapeptide-12 Sp
Skin ConditioningHydrolyzed Collagen
EmollientRosmarinus Officinalis Leaf Extract
AntimicrobialLactic Acid/Glycolic Acid Copolymer
Skin ConditioningGlycerin
HumectantTocopherol
AntioxidantPullulan
Lysolecithin
EmulsifyingSclerotium Gum
Emulsion StabilisingHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingDimethicone
EmollientSodium Phytate
ChelatingDiglycerin
HumectantHydrogenated Lecithin
EmulsifyingSilica
AbrasiveCetyl Alcohol
EmollientHydroxyacetophenone
AntioxidantPolysorbate 60
EmulsifyingSorbitan Isostearate
EmulsifyingSodium Hydroxide
BufferingSodium Benzoate
MaskingPotassium Sorbate
PreservativePolyvinyl Alcohol
Decyl Glucoside
CleansingXanthan Gum
EmulsifyingTocopheryl Acetate
AntioxidantSodium Chloride
MaskingCitric Acid
BufferingPhenoxyethanol
PreservativeWater, Propanediol, Caprylic/Capric Triglyceride, Isopentyldiol, Ethylhexyl Polyhydroxystearate, Squalane, Tetradecane, Glyceryl Stearate Citrate, Butyrospermum Parkii Butter, Polyglyceryl-3 Stearate, Helianthus Annuus Extract, Oryza Sativa Bran Extract, Mannitol, Phosphatidylcholine, Ferulic Acid, Arginine, Acetyl Hexapeptide-8, Copper Palmitoyl Heptapeptide-14, Palmitoyl Sh-Heptapeptide-12 Sp, Hydrolyzed Collagen, Rosmarinus Officinalis Leaf Extract, Lactic Acid/Glycolic Acid Copolymer, Glycerin, Tocopherol, Pullulan, Lysolecithin, Sclerotium Gum, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Dimethicone, Sodium Phytate, Diglycerin, Hydrogenated Lecithin, Silica, Cetyl Alcohol, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Sodium Hydroxide, Sodium Benzoate, Potassium Sorbate, Polyvinyl Alcohol, Decyl Glucoside, Xanthan Gum, Tocopheryl Acetate, Sodium Chloride, Citric Acid, Phenoxyethanol
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".
It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.
The comparison to Botox does have limits because the molecule is water-loving and relatively large.
Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.
So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.
A 12 week human study of a multi-ingredient regimen containing this ingredient saw:
While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).
Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.
Learn more about Acetyl Hexapeptide-8Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources.
It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy.
Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces.
A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks.
Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis.
One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies.
Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne.
Learn more about ArginineGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinSqualane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Learn more about SqualaneWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water