This anti-aging ampoule is formulated around Copper Tripeptide-1 and Adenosine to soften the look of wrinkles and strengthen the skin barrier.
This barrier-repair moisturizer is formulated around Niacinamide and Adenosine to strengthen the skin barrier and hydrate skin.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningStearic Acid
CleansingNeopentyl Glycol Diheptanoate
EmollientCetearyl Olivate
Sorbitan Olivate
EmulsifyingHydrogenated Poly(C6-14 Olefin)
EmollientGlycerin
HumectantCyclomethicone
EmollientButylene Glycol
HumectantCopper Tripeptide-1
Skin ConditioningGlyceryl Stearate
EmollientPEG-100 Stearate
SurfactantPolyacrylate-13
Polyisobutene
Polysorbate 20
EmulsifyingCetearyl Alcohol
EmollientCetearyl Glucoside
EmulsifyingDimethicone
EmollientTrehalose
HumectantTheobroma Cacao Extract
Skin ConditioningCaprylyl Glycol
EmollientEthylhexylglycerin
Skin ConditioningTropolone
Skin ConditioningAmmonium Acryloyldimethyltaurate/Vp Copolymer
Triethanolamine
BufferingCoptis Japonica Extract
AntimicrobialAdenosine
Skin ConditioningPropylene Glycol
HumectantHydrolyzed Extensin
Skin ConditioningRubus Idaeus Fruit Extract
AstringentBeta-Glucan
Skin ConditioningBiosaccharide Gum-1
HumectantIris Florentina Root Extract
MaskingHydrolyzed Wheat Protein
Skin ConditioningPrunus Amygdalus Dulcis Seed Extract
Skin ConditioningLavandula Angustifolia Oil
MaskingDisodium EDTA
ChelatingWater, Stearic Acid, Neopentyl Glycol Diheptanoate, Cetearyl Olivate, Sorbitan Olivate, Hydrogenated Poly(C6-14 Olefin), Glycerin, Cyclomethicone, Butylene Glycol, Copper Tripeptide-1, Glyceryl Stearate, PEG-100 Stearate, Polyacrylate-13, Polyisobutene, Polysorbate 20, Cetearyl Alcohol, Cetearyl Glucoside, Dimethicone, Trehalose, Theobroma Cacao Extract, Caprylyl Glycol, Ethylhexylglycerin, Tropolone, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Triethanolamine, Coptis Japonica Extract, Adenosine, Propylene Glycol, Hydrolyzed Extensin, Rubus Idaeus Fruit Extract, Beta-Glucan, Biosaccharide Gum-1, Iris Florentina Root Extract, Hydrolyzed Wheat Protein, Prunus Amygdalus Dulcis Seed Extract, Lavandula Angustifolia Oil, Disodium EDTA
Water
Skin ConditioningGlycerin
HumectantButylene Glycol
HumectantNiacinamide
SmoothingDipentaerythrityl Hexa C5-9 Acid Esters
Skin ConditioningSodium Hyaluronate
HumectantXanthan Gum
EmulsifyingCyclopentasiloxane
EmollientCyclohexasiloxane
EmollientPolyacrylate-13
Polyisobutene
Polysorbate 20
EmulsifyingHydrogenated Lecithin
EmulsifyingC14-28 Alkyl Acid
Stearyl Alcohol
EmollientBehenyl Alcohol
EmollientDimethicone/Vinyl Dimethicone Crosspolymer
Skin ConditioningDimethicone
EmollientAdenosine
Skin ConditioningGlyceryl Stearate Se
EmulsifyingCetearyl Alcohol
EmollientPolyglyceryl-3 Methylglucose Distearate
EmulsifyingCetyl PEG/PPG-10/1 Dimethicone
EmulsifyingStearic Acid
CleansingTocopheryl Acetate
AntioxidantSodium Polyacrylate
AbsorbentOlea Europaea Fruit Oil
MaskingHelianthus Annuus Seed Oil
EmollientCentella Asiatica Extract
CleansingHippophae Rhamnoides Oil
EmollientArgania Spinosa Kernel Oil
EmollientButyrospermum Parkii Butter
Skin ConditioningCeramide NP
Skin ConditioningTrehalose
HumectantCalendula Officinalis Flower Extract
MaskingCaprylhydroxamic Acid
Chelating1,2-Hexanediol
Skin ConditioningRaphanus Sativus Leaf Extract
HumectantOryza Sativa Bran Extract
Skin ConditioningCucurbitaceae Extract
Skin ConditioningOrchid Extract
Skin ConditioningHoney Extract
HumectantPanax Ginseng Root Extract
EmollientCarthamus Tinctorius Seed Oil
MaskingPhytosphingosine
Skin ConditioningCeteareth-20
CleansingGlyceryl Citrate/Lactate/Linoleate/Oleate
EmulsifyingParfum
MaskingWater, Glycerin, Butylene Glycol, Niacinamide, Dipentaerythrityl Hexa C5-9 Acid Esters, Sodium Hyaluronate, Xanthan Gum, Cyclopentasiloxane, Cyclohexasiloxane, Polyacrylate-13, Polyisobutene, Polysorbate 20, Hydrogenated Lecithin, C14-28 Alkyl Acid, Stearyl Alcohol, Behenyl Alcohol, Dimethicone/Vinyl Dimethicone Crosspolymer, Dimethicone, Adenosine, Glyceryl Stearate Se, Cetearyl Alcohol, Polyglyceryl-3 Methylglucose Distearate, Cetyl PEG/PPG-10/1 Dimethicone, Stearic Acid, Tocopheryl Acetate, Sodium Polyacrylate, Olea Europaea Fruit Oil, Helianthus Annuus Seed Oil, Centella Asiatica Extract, Hippophae Rhamnoides Oil, Argania Spinosa Kernel Oil, Butyrospermum Parkii Butter, Ceramide NP, Trehalose, Calendula Officinalis Flower Extract, Caprylhydroxamic Acid, 1,2-Hexanediol, Raphanus Sativus Leaf Extract, Oryza Sativa Bran Extract, Cucurbitaceae Extract, Orchid Extract, Honey Extract, Panax Ginseng Root Extract, Carthamus Tinctorius Seed Oil, Phytosphingosine, Ceteareth-20, Glyceryl Citrate/Lactate/Linoleate/Oleate, Parfum
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Learn more about AdenosineButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Learn more about Cetearyl AlcoholDimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.
What it does:
Dimethicone comes in different viscosities:
Depending on the viscosity, dimethicone has different properties.
Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.
This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.
Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.
Learn more about DimethiconeGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPolyacrylate-13 is a type of acrylate polymer. Acrylate polymers are commonly used as adhesives in cosmetics.
Polyacrylate-13 creates a film to protect the skin. It is also used to thicken and stabilize a product. It works by making water a gel-like consistency. This gel consistency helps suspend particles.
Polyacrylate-13 is a copolymer of acrylic acid, acrylamide, sodium acrylate, sodium acryloyldimethyltaurate monomers
Learn more about Polyacrylate-13Polyisobutene is a synthetic polymer made from isobutene.
It is a film-forming agent and helps bind ingredients together.
Polyisobutene is not absorbed by the skin.
Learn more about PolyisobutenePolysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.
It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.
The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.
Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).
True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.
Because it is derived from lauric acid, it may not be fungal acne safe.
Learn more about Polysorbate 20Stearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.
In cosmetics, it is a multitasker:
Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.
Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.
Learn more about Stearic AcidTrehalose is a disaccharide made of two glucose molecules (glucose is sugar!). Trehalose is used to help moisturize skin. It also has antioxidant properties.
As a humectant, trehalose helps draw moisture from the air to your skin. This helps keep your skin hydrated.
Due to its antioxidant properties, trehalose may help with signs of aging. Antioxidants help fight free-radical molecules, unstable molecules that may damage your skin.
In medicine, trehalose and hyaluronic acid are used to help treat dry eyes.
Some animals, plants, and bacteria create trehalose as a source of energy to survive freeze or lack of water.
Learn more about TrehaloseWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water