Medik8 Liquid Peptides Versus Numbuzin 9+ NAD Bio Lifting-Sil Essence
Updated on January 16, 2025
Overview
What they are
These products are both cruelty-free and reef safe . They have a total of 18 ingredients in common
Cool Features
They both contain hyaluronic acid and peptides
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any harsh alcohols, common allergens, parabens or sulfates
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Medik8 Liquid Peptides 33 ingredients
Numbuzin 9+ NAD Bio Lifting-Sil Essence 120 ingredients
What's inside (and what isn't)
What's inside (and what isn't)
At a glance
Click on any of the items below to learn more
Medik8 Liquid Peptides 33 ingredients
Numbuzin 9+ NAD Bio Lifting-Sil Essence 120 ingredients
Key Ingredients
Benefits
Concerns
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
Humectant
Butylene Glycol
Humectant
Inulin
Skin ConditioningSodium Hyaluronate
Humectant
Panthenol
Skin Conditioning
Alpha-Glucan Oligosaccharide
CleansingCarnosine
Skin Conditioning
Carbomer
Emulsion StabilisingPolysorbate 20
Emulsifying
Caprylyl Glycol
EmollientPhenoxyethanol
Preservative
Hydroxypropyl Cyclodextrin
MaskingDunaliella Salina Extract
Skin ConditioningEthylhexylglycerin
Skin ConditioningCitric Acid
Buffering
Palmitoyl Tripeptide-5
Skin Conditioning
Sodium Benzoate
Masking
Acetyl Hexapeptide-8
Humectant
Tetrapeptide-21
Skin Conditioning
Pentapeptide-18
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Pantolactone
Humectant
Palmitoyl Tripeptide-38
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Glyceryl Caprylate
EmollientLactic Acid/Glycolic Acid Copolymer
Skin ConditioningPolyvinyl Alcohol
Phenylpropanol
Masking
Copper Palmitoyl Heptapeptide-14
Skin Conditioning
Heptapeptide-15 Palmitate
Skin Conditioning
Potassium Sorbate
Preservative
Xanthan Gum
EmulsifyingWater, Glycerin, Butylene Glycol, Inulin, Sodium Hyaluronate, Panthenol, Alpha-Glucan Oligosaccharide, Carnosine, Carbomer, Polysorbate 20, Caprylyl Glycol, Phenoxyethanol, Hydroxypropyl Cyclodextrin, Dunaliella Salina Extract, Ethylhexylglycerin, Citric Acid, Palmitoyl Tripeptide-5, Sodium Benzoate, Acetyl Hexapeptide-8, Tetrapeptide-21, Pentapeptide-18, Palmitoyl Tripeptide-1, Pantolactone, Palmitoyl Tripeptide-38, Palmitoyl Tetrapeptide-7, Glyceryl Caprylate, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Phenylpropanol, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Potassium Sorbate, Xanthan Gum
Water
Skin ConditioningGlycerin
Humectant
Hydrogenated Poly(C6-14 Olefin)
EmollientPolyglycerin-3
Humectant
Butylene Glycol
Humectant
Pentaerythrityl Tetraethylhexanoate
Emollient
Propanediol
Solvent
Dimethicone
Emollient
1,2-Hexanediol
Skin Conditioning
Niacinamide
Smoothing
Methylpropanediol
SolventCetearyl Alcohol
Emollient
Glyceryl Stearate
Emollient
Hydrogenated Vegetable Oil
Emollient
Polyglyceryl-3 Methylglucose Distearate
Emulsifying
Butyrospermum Parkii Butter
Skin Conditioning
Dimethicone Crosspolymer
Emulsion StabilisingAmmonium Acryloyldimethyltaurate/Vp Copolymer
Sodium Polyacrylate
Absorbent
Hydrogenated Lecithin
Emulsifying
Carbomer
Emulsion StabilisingXanthan Gum
EmulsifyingPentylene Glycol
Skin ConditioningTromethamine
BufferingEthylhexylglycerin
Skin ConditioningAdenosine
Skin Conditioning
Palmitic Acid
Emollient
Stearic Acid
Cleansing
Sodium Phytate
Cholesterol
Emollient
Sodium Hyaluronate
Humectant
Adenosine Triphosphate
Skin ConditioningHydroxypropyl Cyclodextrin
MaskingNicotinamide Adenine Dinucleotide
Skin ConditioningBeta-Glucan
Skin Conditioning
Tocopherol
Antioxidant
Palmitoyl Tripeptide-5
Skin Conditioning
Copper Gluconate
Skin Conditioning
Saccharomyces/Copper Ferment
Skin ConditioningSaccharomyces/Iron Ferment
Skin ConditioningSaccharomyces/Magnesium Ferment
Saccharomyces/Silicon Ferment
Skin ConditioningSaccharomyces/Zinc Ferment
Skin ConditioningCapryloyl Dipeptide-17
Emollient
Thioctic Acid
Antioxidant
Leuconostoc/Radish Root Ferment Filtrate
Antimicrobial
Glutathione
Tremella Fuciformis Extract
Humectant
Haematococcus Pluvialis Oil
Antioxidant
Potassium Hydroxide
BufferingResveratrol
Antioxidant
Hesperidin Methyl Chalcone
Antioxidant
Sorbitan Laurate
Emulsifying
Steareth-20
CleansingAstaxanthin
Skin Conditioning
Sodium Lactate
BufferingHydroxyethylcellulose
Emulsion StabilisingAcetyl Dipeptide-1 Cetyl Ester
Skin Conditioning
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning
Heptasodium Hexacarboxymethyl Dipeptide-12
Skin Conditioning
Panthenol
Skin Conditioning
Polysorbate 20
Emulsifying
Sodium Citrate
BufferingChlorhexidine Digluconate
Antimicrobial
Dextran
Hexapeptide-2
Bleaching
Magnesium Chloride
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate
Skin ConditioningAcetyl Tetrapeptide-5
Humectant
Dipeptide-2
Skin Conditioning
Potassium Sorbate
Preservative
Acetyl Hexapeptide-8
Humectant
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine
Skin Conditioning
Citric Acid
Buffering
Biotin
AntiseborrhoeicPalmitoyl Tetrapeptide-7
Skin Conditioning
Biotinoyl Tripeptide-1
Acetyl Tetrapeptide-3
Skin Protecting
Trifolium Pratense Flower Extract
Astringent
Tocopheryl Acetate
Antioxidant
Palmitoyl Tripeptide-8
Skin Conditioning
Dipeptide-4
Skin Conditioning
Hexapeptide-11
Skin Conditioning
Pentapeptide-18
Skin Conditioning
Tripeptide-3
Skin Conditioning
Sh-Decapeptide-7
Antioxidant
Sh-Octapeptide-4
Antioxidant
Palmitoyl Tripeptide-1
Skin Conditioning
Ascorbic Acid Polypeptide
Antioxidant
Hexapeptide-9
Skin Conditioning
Oligopeptide-3
Skin Conditioning
Palmitoyl Hexapeptide-12
Skin Conditioning
Tripeptide-1
Skin Conditioning
Palmitoyl Pentapeptide-4
Skin Conditioning
Ubiquinone
Antioxidant
Copper Tripeptide-1
Skin Conditioning
Caffeoyl Tripeptide-1
Antioxidant
Caffeoyl Sh-Octapeptide-4
Antioxidant
Galloyl Pentapeptide-33
Antioxidant
Kojyl Carboxy Dipeptide-23
Antioxidant
Nicotinoyl Tripeptide-1
Antioxidant
Octapeptide-7
Skin Protecting
Oligopeptide-1
Skin Conditioning
Sh-Decapeptide-9
Skin Conditioning
Sh-Oligopeptide-9
Humectant
Sh-Pentapeptide-19
Skin Conditioning
Asparagine
MaskingGlutamine
Skin ConditioningTryptophan
MaskingOligopeptide-2
Skin Conditioning
Sh-Oligopeptide-1
Skin Conditioning
Sh-Oligopeptide-2
Skin Conditioning
Sh-Polypeptide-1
Skin Conditioning
Sh-Polypeptide-22
Skin Conditioning
Sh-Polypeptide-3
Skin Conditioning
Acetyl Octapeptide-3
Humectant
Acetyl Tetrapeptide-2
Skin Conditioning
Acetyl Tetrapeptide-9
Skin Conditioning
Carnosine
Skin Conditioning
Nonapeptide-1
Skin Conditioning
Water, Glycerin, Hydrogenated Poly(C6-14 Olefin), Polyglycerin-3, Butylene Glycol, Pentaerythrityl Tetraethylhexanoate, Propanediol, Dimethicone, 1,2-Hexanediol, Niacinamide, Methylpropanediol, Cetearyl Alcohol, Glyceryl Stearate, Hydrogenated Vegetable Oil, Polyglyceryl-3 Methylglucose Distearate, Butyrospermum Parkii Butter, Dimethicone Crosspolymer, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Sodium Polyacrylate, Hydrogenated Lecithin, Carbomer, Xanthan Gum, Pentylene Glycol, Tromethamine, Ethylhexylglycerin, Adenosine, Palmitic Acid, Stearic Acid, Sodium Phytate, Cholesterol, Sodium Hyaluronate, Adenosine Triphosphate, Hydroxypropyl Cyclodextrin, Nicotinamide Adenine Dinucleotide, Beta-Glucan, Tocopherol, Palmitoyl Tripeptide-5, Copper Gluconate, Saccharomyces/Copper Ferment, Saccharomyces/Iron Ferment, Saccharomyces/Magnesium Ferment, Saccharomyces/Silicon Ferment, Saccharomyces/Zinc Ferment, Capryloyl Dipeptide-17, Thioctic Acid, Leuconostoc/Radish Root Ferment Filtrate, Glutathione, Tremella Fuciformis Extract, Haematococcus Pluvialis Oil, Potassium Hydroxide, Resveratrol, Hesperidin Methyl Chalcone, Sorbitan Laurate, Steareth-20, Astaxanthin, Sodium Lactate, Hydroxyethylcellulose, Acetyl Dipeptide-1 Cetyl Ester, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Heptasodium Hexacarboxymethyl Dipeptide-12, Panthenol, Polysorbate 20, Sodium Citrate, Chlorhexidine Digluconate, Dextran, Hexapeptide-2, Magnesium Chloride, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Acetyl Tetrapeptide-5, Dipeptide-2, Potassium Sorbate, Acetyl Hexapeptide-8, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Citric Acid, Biotin, Palmitoyl Tetrapeptide-7, Biotinoyl Tripeptide-1, Acetyl Tetrapeptide-3, Trifolium Pratense Flower Extract, Tocopheryl Acetate, Palmitoyl Tripeptide-8, Dipeptide-4, Hexapeptide-11, Pentapeptide-18, Tripeptide-3, Sh-Decapeptide-7, Sh-Octapeptide-4, Palmitoyl Tripeptide-1, Ascorbic Acid Polypeptide, Hexapeptide-9, Oligopeptide-3, Palmitoyl Hexapeptide-12, Tripeptide-1, Palmitoyl Pentapeptide-4, Ubiquinone, Copper Tripeptide-1, Caffeoyl Tripeptide-1, Caffeoyl Sh-Octapeptide-4, Galloyl Pentapeptide-33, Kojyl Carboxy Dipeptide-23, Nicotinoyl Tripeptide-1, Octapeptide-7, Oligopeptide-1, Sh-Decapeptide-9, Sh-Oligopeptide-9, Sh-Pentapeptide-19, Asparagine, Glutamine, Tryptophan, Oligopeptide-2, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-22, Sh-Polypeptide-3, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Acetyl Tetrapeptide-9, Carnosine, Nonapeptide-1
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterGlycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolSodium Hyaluronate is hyaluronic acid's salt form. It is commonly derived from the sodium salt of hyaluronic acid.
Like hyaluronic acid, it is great at holding water and acts as a humectant. This makes it a great skin hydrating ingredient.
Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.
These are some other common types of Hyaluronic Acid:
Learn more about Sodium HyaluronatePanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolCarnosine is a dipeptide made from two amino acids.
This ingredient helps:
Glycation is the process of sugars binding to and damaging proteins. Too much sugar in our skin can lead to damaged collagen, contributing to factors of aging.
Carnosine is water-soluble and is not able to travel deeper layers of skin. This leads to some doubt about whether it can boost collagen in skin, since collagen is located in the deeper layers of skin.
Fun fact: Carnosine can be naturally found in our muscles and brain.
Learn more about CarnosineCarbomer is a polymer of acrylic acid. Its main role is to create a gel consistency.
A high amount of carbomer can cause pilling or balling up of products. Don't worry, most products contain 1% or less of carbomer.
Polysorbate 20 is made by combining ethoxylation of sorbitan, ethylene oxide, and lauric acid. It is a mild cleansing agent, surfactant, and emulsifier.
As a surfactant, it helps collect dirt and oils for washing. Emulsifiers prevent oils and water from separating.
Polysorbate 20 also adds scent to a product. Since it is made using sorbitol, it has a sweet scent. Sorbitol can also be found in fruits such as apples and peaches.
The lauric acid used to create Polysorbate 20 is often derived from coconuts.
Polysorbate 20 may not be fungal acne safe.
Learn more about Polysorbate 20We don't have a description for Hydroxypropyl Cyclodextrin yet.
Ethylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Citric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.
If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.
Read more about some other popular AHA's here:
Learn more about Citric AcidThis synthetic peptide is created from lysine, valine, and palmitic acid.
According to the manufacturer, in-vitro studies show tissue growth and collagen synthesis. Another in-vivo study found 60 volunteers saw a significant reduction in wrinkles after 84 days.
Due to its palmitic acid base, this peptide may not be fungal-acne safe.
Learn more about Palmitoyl Tripeptide-5Acetyl Hexapeptide-8, commonly known as Argireline, is a popular peptide in skincare. It’s often referred to as a “Botox-like” ingredient because it helps reduce muscle movement.
By relaxing these micro-movements, Argireline may help minimize the appearance of fine lines and wrinkles. That said, it’s not as powerful as Botox, and research on its long-term effectiveness is still limited.
Beyond smoothing, Argireline may also support collagen production. Collagen is the protein that helps keep your skin firm, bouncy, and well-hydrated by strengthening the skin barrier.
So while Argireline isn’t a miracle fix, it can be a helpful addition to a routine focused on both prevention and skin health.
Read more about other common types of peptides here:
Learn more about Acetyl Hexapeptide-8This peptide is more commonly known as Leuphasyl. It has similar properties to argireline, the "botox peptide".
According to a manufacturer, Pentapeptide-18 mimics botulinum to freeze muscles and reduce the appearance of wrinkles. Their study found this 5% of this ingredient reduced wrinkles by 11%.
Combining this ingredient with Argireline showed improved results.
Learn more about Pentapeptide-18Palmitoyl Tripeptide-1 is a 3-amino acid peptide. Peptides are building blocks for protein.
This ingredient is a signal peptide, meaning it tells our skin to create collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Palmitoyl Tripeptide-1 can help reduce wrinkles and make the skin look more youthful.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tripeptide-1Palmitoyl Tetrapeptide-7 is a peptide. Peptides are building blocks for protein.
This ingredient consists of four amino acids and palmitic acid. These amino acids are arginine, proline, glutamine, and glycine.
This ingredient has many benefits. These benefits include boosting collagen production, fighting inflammation, and reversing UV damage.
By preventing our bodies from producing interleukins, Palmitoyl Tetrapeptide-7 helps fight inflammation. An interleukin is a chemical that signals to the body to produce an inflammatory response. Interleukin production is accelerated by UV radiation.
Palmitoyl Tetrapeptide-7 tells our body to create more collagen. Collagen is a protein that makes connective tissue. Boosting collagen production leads to a healthier skin barrier. Having a healthy skin barrier means having firm and hydrated skin.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tetrapeptide-7Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Learn more about Potassium SorbateXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumIngredient Ratings
Here's what our community thinks of the ingredients in these products.
When to use
Medik8 Liquid Peptides 33 ingredients
Numbuzin 9+ NAD Bio Lifting-Sil Essence 120 ingredients
Reviews
Here's what our community thinks
Medik8 Liquid Peptides 33 ingredients
I love this product. It has become a staple in my routine. It's such a shame they increased the price, but I rotate between this one and the ordinary multipeptide with copper. It's the perfect consistency and it does not get sticky, but it needs to be applied scarcely (around 4 drops). My skin loves this serum and it makes the skin hydrated without creating any excess oil. It does not trigger any Show more
It’s water based and firms my skin. My skin loves it. I also like Bare Minerals Herb Serum as it has niacinamide and my skin loves that too. Medik8 Crystal Retinal 3 and 6 also. Elemis pro rad cream wash and dynamic resurf and kefir mist
