La Roche-Posay Hydraphase HA Rich Hyaluronic Acid Face Cream Versus Dermalogica Skin Smoothing Cream
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
HumectantIsopropyl Palmitate
EmollientButyrospermum Parkii Butter
Skin ConditioningLauroyl Lysine
Skin ConditioningCetyl Alcohol
EmollientUrea
BufferingPEG-100 Stearate
SurfactantGlyceryl Stearate
EmollientCera Alba
EmollientPentylene Glycol
Skin ConditioningStearic Acid
CleansingCarbomer
Emulsion StabilisingGlyceryl Acrylate/Acrylic Acid Copolymer
HumectantSodium Hyaluronate
HumectantSodium Hydroxide
BufferingMyristic Acid
CleansingPalmitic Acid
EmollientHydrolyzed Hyaluronic Acid
HumectantCaprylyl Glycol
EmollientCitric Acid
BufferingTrisodium Ethylenediamine Disuccinate
Xanthan Gum
EmulsifyingPolysorbate 60
EmulsifyingPentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate
AntioxidantChlorphenesin
AntimicrobialParfum
MaskingWater, Glycerin, Isopropyl Palmitate, Butyrospermum Parkii Butter, Lauroyl Lysine, Cetyl Alcohol, Urea, PEG-100 Stearate, Glyceryl Stearate, Cera Alba, Pentylene Glycol, Stearic Acid, Carbomer, Glyceryl Acrylate/Acrylic Acid Copolymer, Sodium Hyaluronate, Sodium Hydroxide, Myristic Acid, Palmitic Acid, Hydrolyzed Hyaluronic Acid, Caprylyl Glycol, Citric Acid, Trisodium Ethylenediamine Disuccinate, Xanthan Gum, Polysorbate 60, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Chlorphenesin, Parfum
Water
Skin ConditioningCaprylic/Capric Triglyceride
MaskingEthylhexyl Hydroxystearate
EmollientStearic Acid
CleansingButylene Glycol
HumectantGlycerin
HumectantAloe Barbadensis Extract
Skin ConditioningDimethicone
EmollientPEG-8
HumectantCetearyl Alcohol
EmollientSodium Hyaluronate
HumectantVitis Vinifera Seed Extract
AntimicrobialSaccharide Isomerate
HumectantCucumis Sativus Fruit Extract
EmollientArnica Montana Flower Extract
MaskingHedera Helix Extract
AntimicrobialMalva Sylvestris Flower Extract
Skin ConditioningParietaria Officinalis Extract
EmollientSambucus Nigra Flower Extract
RefreshingAscorbyl Palmitate
AntioxidantTrehalose
HumectantAlgin
MaskingHydrolyzed Sodium Hyaluronate
Skin ConditioningSerine
MaskingLinoleic Acid
CleansingPhospholipids
Skin ConditioningPhytosterols
Skin ConditioningCananga Odorata Flower Oil
MaskingUrea
BufferingHydrogenated Lecithin
EmulsifyingPullulan
Caprylhydroxamic Acid
Citrus Aurantium Amara Flower Extract
RefreshingTocopheryl Acetate
AntioxidantTetrasodium Glutamate Diacetate
Hexanediol
SolventPentylene Glycol
Skin ConditioningGlyceryl Polyacrylate
Sodium Citrate
BufferingDisodium Phosphate
BufferingPalmitoyl Hydroxypropyltrimonium Amylopectin/Glycerin Crosspolymer
Skin ConditioningCaprylyl Glycol
EmollientPotassium Phosphate
BufferingCitric Acid
BufferingTocopherol
AntioxidantMethylpropanediol
SolventPolysorbate 60
EmulsifyingPanthenol
Skin ConditioningPolyquaternium-10
Cetyl Alcohol
EmollientPEG-100 Stearate
SurfactantGlyceryl Stearate
EmollientAminomethyl Propanol
BufferingCarbomer
Emulsion StabilisingEthylhexylglycerin
Skin ConditioningSodium Hydroxide
BufferingHydroxystearic Acid
CleansingBHT
AntioxidantBenzyl Benzoate
AntimicrobialBenzyl Salicylate
PerfumingLinalool
PerfumingSodium Benzoate
MaskingPhenoxyethanol
PreservativeWater, Caprylic/Capric Triglyceride, Ethylhexyl Hydroxystearate, Stearic Acid, Butylene Glycol, Glycerin, Aloe Barbadensis Extract, Dimethicone, PEG-8, Cetearyl Alcohol, Sodium Hyaluronate, Vitis Vinifera Seed Extract, Saccharide Isomerate, Cucumis Sativus Fruit Extract, Arnica Montana Flower Extract, Hedera Helix Extract, Malva Sylvestris Flower Extract, Parietaria Officinalis Extract, Sambucus Nigra Flower Extract, Ascorbyl Palmitate, Trehalose, Algin, Hydrolyzed Sodium Hyaluronate, Serine, Linoleic Acid, Phospholipids, Phytosterols, Cananga Odorata Flower Oil, Urea, Hydrogenated Lecithin, Pullulan, Caprylhydroxamic Acid, Citrus Aurantium Amara Flower Extract, Tocopheryl Acetate, Tetrasodium Glutamate Diacetate, Hexanediol, Pentylene Glycol, Glyceryl Polyacrylate, Sodium Citrate, Disodium Phosphate, Palmitoyl Hydroxypropyltrimonium Amylopectin/Glycerin Crosspolymer, Caprylyl Glycol, Potassium Phosphate, Citric Acid, Tocopherol, Methylpropanediol, Polysorbate 60, Panthenol, Polyquaternium-10, Cetyl Alcohol, PEG-100 Stearate, Glyceryl Stearate, Aminomethyl Propanol, Carbomer, Ethylhexylglycerin, Sodium Hydroxide, Hydroxystearic Acid, BHT, Benzyl Benzoate, Benzyl Salicylate, Linalool, Sodium Benzoate, Phenoxyethanol
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolCarbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Learn more about CarbomerCetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product.
Its main roles are:
Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol.
The FDA allows products labeled "alcohol-free" to have fatty alcohols.
This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.
Learn more about Cetyl AlcoholCitric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.
Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.
However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.
Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.
In skincare formulas, citric acid can:
While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.
Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.
Read more about some other popular AHA's here:
Learn more about Citric AcidGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinGlyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.
Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.
This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.
A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.
Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.
Fun fact: The human body also creates Glyceryl Stearate naturally.
Learn more about Glyceryl StearatePeg-100 Stearate is an emollient and emulsifier. As an emollient, it helps keep skin soft by trapping moisture in. On the other hand, emulsifiers help prevent oil and water from separating in a product.
PEGS are a hydrophilic polyether compound . There are 100 ethylene oxide monomers in Peg-100 Stearate. Peg-100 Stearate is polyethylene glycol ester of stearic acid.
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolPolysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.
Polysorbate 60 is sorbitol-based and created from the ethoxylation of sorbitan. Ethoxylation is a chemical reaction used to add ethylene oxide. Sorbitan is a the dehydrated version of sorbitol, a sugar found in fruits.
In this case, the 60 comes from reacting 60 units of ethylene oxide with sorbitan.
Polysorbates are commonly used in medicine and foods.
Learn more about Polysorbate 60Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateSodium Hydroxide is also known as lye or caustic soda. It is used to adjust the pH of products; many ingredients require a specific pH to be effective.
In small amounts, sodium hydroxide is considered safe to use. However, large amounts may cause chemical burns due to its high alkaline.
Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.
"Alkaline" refers to a high pH level. A low pH level would be considered acidic.
Learn more about Sodium HydroxideStearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.
In cosmetics, it is a multitasker:
Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.
Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.
Learn more about Stearic AcidUrea is also called carbamide and is the diamide of carbonic acid. In cosmetics, urea is used to hydrate the skin. It also provides exfoliation in higher concentrations.
As a humectant, urea helps draw moisture from the air and from deep within the skin. This helps hydrate your skin. Studies show urea is an effective moisturizer for dry skin conditions. 40% urea is typical in medications for treating eczema and other skin conditions.
Urea has the strongest exfoliation effect in concentrations higher than 10%. It is a keratolytic agent, meaning it breaks down the keratin protein in the top layer of skin. This helps remove dead skin cells and flaking skin.
In medicine, urea has been shown to help increase the potency of other ingredients, such as fungal treatments.
Humans and animals use urea to metabolize nitrogen-containing compounds. Urea is highly soluble in water. Once dissolved, it is neither acidic nor alkaline.
Urea is actually one of the more well-studied and well-supported ingredients out there if you have eczema.
Clinical trials have shown that urea creams in the 5 - 10% range can:
Higher concentrations (20 -30%) can also help with thickened, scaly patches but is also more likely to sting on active flares.
Skip urea if you have rosacea. The AAD (American Academy of Dermatology) lists it alongside alcohol, menthol, and fragrance as a potential irritant for rosacea-prone skin. Urea's keratolytic and penetration-enhancing properties can trigger stinging, burning, and redness.
As always, your skin is unique, so definitely check in with your dermatologist.
Learn more about UreaWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water