SKIN1004 Madagascar Centella Probio-Cica Intensive Ampoule Versus Paula's Choice Omega+ Complex Serum
This barrier-repair ampoule is formulated around Niacinamide and Centella Asiatica Extract to strengthen the skin barrier and calm redness.
This barrier-repair serum is formulated around Linoleic Acid and Linolenic Acid to strengthen the skin barrier and hydrate skin.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningButylene Glycol
HumectantGlycerin
HumectantPropanediol
SolventCaprylic/Capric Triglyceride
MaskingNiacinamide
Smoothing1,2-Hexanediol
Skin ConditioningDipropylene Glycol
HumectantCentella Asiatica Extract
CleansingPolyglyceryl-3 Distearate
EmulsifyingAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingC14-22 Alcohols
Emulsion StabilisingArginine
MaskingHydrogenated Lecithin
EmulsifyingHydroxystearic Acid
CleansingBetaine
HumectantPanthenol
Skin ConditioningAllantoin
Skin ConditioningEthylhexylglycerin
Skin ConditioningHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingAdenosine
Skin ConditioningGlyceryl Stearate Citrate
EmollientSodium Polyacrylate
AbsorbentC12-20 Alkyl Glucoside
EmulsifyingCetearyl Alcohol
EmollientXanthan Gum
EmulsifyingMacadamia Ternifolia Seed Oil
EmollientSodium Hyaluronate
HumectantSodium Phytate
Stearic Acid
CleansingCeramide NP
Skin ConditioningSorbitan Isostearate
EmulsifyingGlyceryl Acrylate/Acrylic Acid Copolymer
HumectantLactobacillus Ferment
Skin ConditioningPolyglyceryl-10 Myristate
Skin ConditioningMadecassic Acid
Skin ConditioningAsiaticoside
AntioxidantPhytosphingosine
Skin ConditioningAsiatic Acid
Skin ConditioningSucrose Distearate
EmollientPolyglutamic Acid
Skin ConditioningLauric Acid
CleansingPhytosterols
Skin ConditioningWater, Butylene Glycol, Glycerin, Propanediol, Caprylic/Capric Triglyceride, Niacinamide, 1,2-Hexanediol, Dipropylene Glycol, Centella Asiatica Extract, Polyglyceryl-3 Distearate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, C14-22 Alcohols, Arginine, Hydrogenated Lecithin, Hydroxystearic Acid, Betaine, Panthenol, Allantoin, Ethylhexylglycerin, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Adenosine, Glyceryl Stearate Citrate, Sodium Polyacrylate, C12-20 Alkyl Glucoside, Cetearyl Alcohol, Xanthan Gum, Macadamia Ternifolia Seed Oil, Sodium Hyaluronate, Sodium Phytate, Stearic Acid, Ceramide NP, Sorbitan Isostearate, Glyceryl Acrylate/Acrylic Acid Copolymer, Lactobacillus Ferment, Polyglyceryl-10 Myristate, Madecassic Acid, Asiaticoside, Phytosphingosine, Asiatic Acid, Sucrose Distearate, Polyglutamic Acid, Lauric Acid, Phytosterols
Water
Skin ConditioningGlycerin
HumectantDiheptyl Succinate
EmollientCandelilla/Jojoba/Rice Bran Polyglyceryl-3 Esters
EmulsifyingLinum Usitatissimum Seed Oil
PerfumingLinoleic Acid
CleansingLinolenic Acid
CleansingPassiflora Edulis Seed Oil
EmollientCeramide EOP
Skin ConditioningCeramide Eos
Skin ConditioningCeramide NP
Skin ConditioningCeramide Ns
Skin ConditioningCaprooyl Sphingosine
Skin ConditioningOlea Europaea Oil Unsaponifiables
Skin ConditioningCaprooyl Phytosphingosine
Skin ConditioningSodium Hyaluronate
HumectantCholesterol
EmollientCeramide AP
Skin ConditioningButyrospermum Parkii Butter Unsaponifiables
Skin ConditioningTocopherol
AntioxidantHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingPrunus Domestica Seed Oil
Skin ConditioningLauryl Laurate
Skin ConditioningGlyceryl Behenate
EmollientHydrogenated Lecithin
EmulsifyingSodium Phytate
Trehalose
HumectantIsohexadecane
EmollientSodium Stearoyl Lactylate
EmulsifyingCapryloyl Glycerin/Sebacic Acid Copolymer
Skin ConditioningXanthan Gum
EmulsifyingCetyl Alcohol
EmollientTetrahexyldecyl Ascorbate
AntioxidantAgar
MaskingGlyceryl Stearate
EmollientCeteareth-25
CleansingCetearyl Alcohol
EmollientBehenic Acid
CleansingGlyceryl Rosinate
PerfumingCitric Acid
BufferingBenzyl Alcohol
PerfumingEthylhexylglycerin
Skin ConditioningWater, Glycerin, Diheptyl Succinate, Candelilla/Jojoba/Rice Bran Polyglyceryl-3 Esters, Linum Usitatissimum Seed Oil, Linoleic Acid, Linolenic Acid, Passiflora Edulis Seed Oil, Ceramide EOP, Ceramide Eos, Ceramide NP, Ceramide Ns, Caprooyl Sphingosine, Olea Europaea Oil Unsaponifiables, Caprooyl Phytosphingosine, Sodium Hyaluronate, Cholesterol, Ceramide AP, Butyrospermum Parkii Butter Unsaponifiables, Tocopherol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Prunus Domestica Seed Oil, Lauryl Laurate, Glyceryl Behenate, Hydrogenated Lecithin, Sodium Phytate, Trehalose, Isohexadecane, Sodium Stearoyl Lactylate, Capryloyl Glycerin/Sebacic Acid Copolymer, Xanthan Gum, Cetyl Alcohol, Tetrahexyldecyl Ascorbate, Agar, Glyceryl Stearate, Ceteareth-25, Cetearyl Alcohol, Behenic Acid, Glyceryl Rosinate, Citric Acid, Benzyl Alcohol, Ethylhexylglycerin
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.
Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.
This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.
Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.
Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.
Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.
Learn more about Ceramide NPCetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.
Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.
It plays several roles in a formula:
Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.
Multiple assessments have found it to be non-irritating and non-sensitizing to most people.
However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.
Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.
Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.
Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.
This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.
A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.
Learn more about Cetearyl AlcoholEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinHydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Learn more about Hydrogenated LecithinThis is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.
It is also an emulsifer, meaning it prevents ingredients such as oil and water from separating. It also helps evenly disperse other ingredients.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Learn more about Sodium HyaluronateSodium Phytate is the synthetic salt form of phytic acid. Phytic acid is an antioxidant and can be found in plant seeds.
Sodium Phytate is a chelating agent. Chelating agents help prevent metals from binding to water. This helps stabilize the ingredients and the product.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan Gum