Medik8 Liquid Peptides Versus Numbuzin No.9 NAD+ PDRN Glow Boosting Toner
Updated on July 16, 2025
Overview
What they are
These products are both cruelty-free and reef safe . They have a total of 11 ingredients in common
Cool Features
They both contain AHA and peptides
Suited For
They're both likely to be good for anti aging, dry skin, brightening skin, sensitive skin, oily skin, reducing pores, scar healing, dark spots and better texture
Free From
They both do not contain any common allergens, parabens, silicones or sulfates
What's Inside
They both contain fragrances
We independently verify ingredients, and our claims are backed by peer-reviewed research. Spot a product that needs an update? Let us know.
Ingredient Info
Medik8 Liquid Peptides 33 ingredients
Numbuzin No.9 NAD+ PDRN Glow Boosting Toner 125 ingredients
What's inside
What's inside
At a glance
Click on any of the items below to learn more
Medik8 Liquid Peptides 33 ingredients
Numbuzin No.9 NAD+ PDRN Glow Boosting Toner 125 ingredients
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
Humectant
Butylene Glycol
Humectant
Inulin
Skin ConditioningSodium Hyaluronate
Humectant
Panthenol
Skin Conditioning
Alpha-Glucan Oligosaccharide
CleansingCarnosine
Skin Conditioning
Carbomer
Emulsion StabilisingPolysorbate 20
Emulsifying
Caprylyl Glycol
Emollient
Phenoxyethanol
Preservative
Hydroxypropyl Cyclodextrin
MaskingDunaliella Salina Extract
Skin ConditioningEthylhexylglycerin
Skin ConditioningCitric Acid
Buffering
Palmitoyl Tripeptide-5
Skin Conditioning
Sodium Benzoate
Masking
Acetyl Hexapeptide-8
Humectant
Tetrapeptide-21
Skin Conditioning
Pentapeptide-18
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Pantolactone
Humectant
Palmitoyl Tripeptide-38
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Glyceryl Caprylate
EmollientLactic Acid/Glycolic Acid Copolymer
Skin ConditioningPolyvinyl Alcohol
Phenylpropanol
Masking
Copper Palmitoyl Heptapeptide-14
Skin Conditioning
Heptapeptide-15 Palmitate
Skin Conditioning
Potassium Sorbate
Preservative
Xanthan Gum
EmulsifyingWater, Glycerin, Butylene Glycol, Inulin, Sodium Hyaluronate, Panthenol, Alpha-Glucan Oligosaccharide, Carnosine, Carbomer, Polysorbate 20, Caprylyl Glycol, Phenoxyethanol, Hydroxypropyl Cyclodextrin, Dunaliella Salina Extract, Ethylhexylglycerin, Citric Acid, Palmitoyl Tripeptide-5, Sodium Benzoate, Acetyl Hexapeptide-8, Tetrapeptide-21, Pentapeptide-18, Palmitoyl Tripeptide-1, Pantolactone, Palmitoyl Tripeptide-38, Palmitoyl Tetrapeptide-7, Glyceryl Caprylate, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Phenylpropanol, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Potassium Sorbate, Xanthan Gum
Water
Skin ConditioningMethylpropanediol
SolventNiacinamide
Smoothing
PEG/PPG-17/6 Copolymer
SolventPropanediol
Solvent
1,2-Hexanediol
Skin Conditioning
Tripropylene Glycol
Antioxidant
Glyceryl Glucoside
Humectant
Xylitylglucoside
Humectant
PEG-40 Hydrogenated Castor Oil
Emulsifying
Anhydroxylitol
Humectant
Glycerin
Humectant
Polyglyceryl-10 Laurate
Skin Conditioning
Candida Bombicola/Glucose/Methyl Rapeseedate Ferment
AntimicrobialC20-40 Pareth-10
EmulsifyingTocopheryl Acetate
Antioxidant
Xylitol
Humectant
Cetearyl Alcohol
Emollient
Sodium Dna
Skin Conditioning
Hydrogenated Lecithin
Emulsifying
Glucose
Humectant
Polyacrylate Crosspolymer-6
Emulsion StabilisingEthylhexylglycerin
Skin ConditioningAdenosine
Skin Conditioning
Ceramide NP
Skin Conditioning
Sodium Phytate
Helianthus Annuus Seed Oil
Emollient
Melia Azadirachta Leaf Extract
Skin ConditioningMelia Azadirachta Flower Extract
Skin ConditioningCitric Acid
Buffering
Hydroxyethylcellulose
Emulsion StabilisingSodium Citrate
BufferingPhytosterols
Skin Conditioning
Coccinia Indica Fruit Extract
Skin ConditioningAloe Barbadensis Flower Extract
EmollientSolanum Melongena Fruit Extract
Skin ConditioningT-Butyl Alcohol
Perfuming
Ocimum Sanctum Leaf Extract
Skin Conditioning
Curcuma Longa Root Extract
Masking
Corallina Officinalis Extract
Skin Conditioning
Cyanocobalamin
Skin ConditioningCaprylic/Capric Triglyceride
Masking
Hydrolyzed Collagen
Emollient
Butylene Glycol
Humectant
Adenosine Triphosphate
Skin ConditioningNicotinamide Adenine Dinucleotide
Skin ConditioningResveratrol
Antioxidant
Pullulan
Sodium Palmitoyl Sarcosinate
CleansingPalmitic Acid
Emollient
C12-14 Alketh-12
EmulsifyingPisum Sativum Peptide
Skin Conditioning
Stearic Acid
Cleansing
Polyglyceryl-6 Laurate
Emulsifying
Caprylyl Glycol
Emollient
Dipeptide Diaminobutyroyl Benzylamide Diacetate
Skin Conditioning
Dextran
Hydrolyzed Elastin
EmollientSoluble Collagen
Humectant
Acetyl Tetrapeptide-3
Skin Protecting
Trifolium Pratense Flower Extract
Astringent
Disodium EDTA
Myristic Acid
Cleansing
Acetyl Hexapeptide-8
Humectant
Mannose
HumectantSh-Octapeptide-4
Antioxidant
Sh-Decapeptide-7
Antioxidant
Palmitoyl Pentapeptide-4
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Copper Tripeptide-1
Skin Conditioning
Hexapeptide-9
Skin Conditioning
Nonapeptide-1
Skin Conditioning
Tripeptide-1
Skin Conditioning
Arachidic Acid
Cleansing
Collagen
Moisturising
Elastin
Skin ConditioningGlutathione
Palmitoyl Tetrapeptide-7
Skin Conditioning
Arginine/Lysine Polypeptide
Skin Conditioning
Oligopeptide-29
Antioxidant
Oligopeptide-32
Antiseborrhoeic
Acetyl Tetrapeptide-5
Humectant
Acetyl Tetrapeptide-9
Skin Conditioning
Acetyl Tetrapeptide-2
Skin Conditioning
Acetyl Octapeptide-3
Humectant
Acetyl Hexapeptide-1
Skin Conditioning
Alanine/Histidine/Lysine Polypeptide Copper Hcl
Skin Conditioning
Acetyl Dipeptide-1 Cetyl Ester
Skin Conditioning
Acetyl Sh-Pentapeptide-1
Skin Conditioning
Biotinoyl Tripeptide-1
Dipeptide-4
Skin Conditioning
Hexapeptide-11
Skin Conditioning
Hexapeptide-12
Skin Conditioning
Lauric Acid
Cleansing
Myristoyl Pentapeptide-17
Skin Conditioning
Myristoyl Hexapeptide-16
Skin Conditioning
Myristoyl Pentapeptide-4
Skin Conditioning
Nicotinoyl Tripeptide-1
Antioxidant
Nonapeptide-7
Skin Conditioning
Nicotinoyl Tripeptide-35
Antioxidant
Nicotinoyl Dipeptide-26
Skin Conditioning
Nicotinoyl Dipeptide-23
Skin Conditioning
Octapeptide-2
Skin Conditioning
Palmitoyl Tripeptide-5
Skin Conditioning
Palmitoyl Hexapeptide-12
Skin Conditioning
Pentapeptide-13
Skin Conditioning
Palmitoyl Tetrapeptide-10
Skin Conditioning
Palmitoyl Tripeptide-38
Skin Conditioning
Palmitoyl Tripeptide-29
Skin Conditioning
Palmitoyl Tripeptide-8
Skin Conditioning
Sr-(Oligopeptide-91 Clostridium Botulinum Polypeptide-1)
Skin Conditioning
Tetrapeptide-44
Skin Conditioning
Tetrapeptide-30
Skin Conditioning
Tripeptide-10 Citrulline
Skin Conditioning
Tripeptide-32
Skin Conditioning
Tripeptide-29
Skin Conditioning
Sh-Polypeptide-22
Skin Conditioning
Sh-Oligopeptide-1
Skin Conditioning
Sh-Polypeptide-1
Skin Conditioning
Sh-Polypeptide-9
Skin Conditioning
Sh-Oligopeptide-2
Skin Conditioning
Sh-Polypeptide-11
Sh-Polypeptide-3
Skin Conditioning
Sh-Polypeptide-16
Skin Protecting
Sh-Polypeptide-62
Antioxidant
Water, Methylpropanediol, Niacinamide, PEG/PPG-17/6 Copolymer, Propanediol, 1,2-Hexanediol, Tripropylene Glycol, Glyceryl Glucoside, Xylitylglucoside, PEG-40 Hydrogenated Castor Oil, Anhydroxylitol, Glycerin, Polyglyceryl-10 Laurate, Candida Bombicola/Glucose/Methyl Rapeseedate Ferment, C20-40 Pareth-10, Tocopheryl Acetate, Xylitol, Cetearyl Alcohol, Sodium Dna, Hydrogenated Lecithin, Glucose, Polyacrylate Crosspolymer-6, Ethylhexylglycerin, Adenosine, Ceramide NP, Sodium Phytate, Helianthus Annuus Seed Oil, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Citric Acid, Hydroxyethylcellulose, Sodium Citrate, Phytosterols, Coccinia Indica Fruit Extract, Aloe Barbadensis Flower Extract, Solanum Melongena Fruit Extract, T-Butyl Alcohol, Ocimum Sanctum Leaf Extract, Curcuma Longa Root Extract, Corallina Officinalis Extract, Cyanocobalamin, Caprylic/Capric Triglyceride, Hydrolyzed Collagen, Butylene Glycol, Adenosine Triphosphate, Nicotinamide Adenine Dinucleotide, Resveratrol, Pullulan, Sodium Palmitoyl Sarcosinate, Palmitic Acid, C12-14 Alketh-12, Pisum Sativum Peptide, Stearic Acid, Polyglyceryl-6 Laurate, Caprylyl Glycol, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Dextran, Hydrolyzed Elastin, Soluble Collagen, Acetyl Tetrapeptide-3, Trifolium Pratense Flower Extract, Disodium EDTA, Myristic Acid, Acetyl Hexapeptide-8, Mannose, Sh-Octapeptide-4, Sh-Decapeptide-7, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Copper Tripeptide-1, Hexapeptide-9, Nonapeptide-1, Tripeptide-1, Arachidic Acid, Collagen, Elastin, Glutathione, Palmitoyl Tetrapeptide-7, Arginine/Lysine Polypeptide, Oligopeptide-29, Oligopeptide-32, Acetyl Tetrapeptide-5, Acetyl Tetrapeptide-9, Acetyl Tetrapeptide-2, Acetyl Octapeptide-3, Acetyl Hexapeptide-1, Alanine/Histidine/Lysine Polypeptide Copper Hcl, Acetyl Dipeptide-1 Cetyl Ester, Acetyl Sh-Pentapeptide-1, Biotinoyl Tripeptide-1, Dipeptide-4, Hexapeptide-11, Hexapeptide-12, Lauric Acid, Myristoyl Pentapeptide-17, Myristoyl Hexapeptide-16, Myristoyl Pentapeptide-4, Nicotinoyl Tripeptide-1, Nonapeptide-7, Nicotinoyl Tripeptide-35, Nicotinoyl Dipeptide-26, Nicotinoyl Dipeptide-23, Octapeptide-2, Palmitoyl Tripeptide-5, Palmitoyl Hexapeptide-12, Pentapeptide-13, Palmitoyl Tetrapeptide-10, Palmitoyl Tripeptide-38, Palmitoyl Tripeptide-29, Palmitoyl Tripeptide-8, Sr-(Oligopeptide-91 Clostridium Botulinum Polypeptide-1), Tetrapeptide-44, Tetrapeptide-30, Tripeptide-10 Citrulline, Tripeptide-32, Tripeptide-29, Sh-Polypeptide-22, Sh-Oligopeptide-1, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Oligopeptide-2, Sh-Polypeptide-11, Sh-Polypeptide-3, Sh-Polypeptide-16, Sh-Polypeptide-62
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Acetyl Hexapeptide-8, commonly known as Argireline, is a popular peptide in skincare. It’s often referred to as a “Botox-like” ingredient because it helps reduce muscle movement.
By relaxing these micro-movements, Argireline may help minimize the appearance of fine lines and wrinkles. That said, it’s not as powerful as Botox, and research on its long-term effectiveness is still limited.
Beyond smoothing, Argireline may also support collagen production. Collagen is the protein that helps keep your skin firm, bouncy, and well-hydrated by strengthening the skin barrier.
So while Argireline isn’t a miracle fix, it can be a helpful addition to a routine focused on both prevention and skin health.
Read more about other common types of peptides here:
Learn more about Acetyl Hexapeptide-8Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolCaprylyl Glycol is a humectant and emollient, meaning it attracts and preserves moisture.
It is a common ingredient in many products, especially those designed to hydrate skin. The primary benefits are retaining moisture, skin softening, and promoting a healthy skin barrier.
Though Caprylyl Glycol is an alcohol derived from fatty acids, it is not the kind that can dry out skin.
This ingredient is also used as a preservative to extend the life of products. It has slight antimicrobial properties.
Learn more about Caprylyl GlycolCitric Acid is an AHA derived from citrus fruits (think oranges, lemons, and limes!).
As an AHA, Citric Acid removes the top layer of skin cells from the newer layer of skin underneath. This helps skin to remove dark spots and even out skin tone.
If you spot Citric Acid near the end of an ingredient list, it's likely there as a pH adjuster rather than an active ingredient.
Read more about some other popular AHA's here:
Learn more about Citric AcidEthylhexylglycerin (we can't pronounce this either) is commonly used as a preservative and skin softener. It is derived from glyceryl.
You might see Ethylhexylglycerin often paired with other preservatives such as phenoxyethanol. Ethylhexylglycerin has been found to increase the effectiveness of these other preservatives.
Glycerin is already naturally found in your skin. It helps moisturize and protect your skin.
A study from 2016 found glycerin to be more effective as a humectant than AHAs and hyaluronic acid.
As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.
Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.
Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.
In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.
This ingredient is organic, colorless, odorless, and non-toxic.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPalmitoyl Tetrapeptide-7 is a lab-made peptide with anti-inflammatory and skin-repairing benefits. It's made up of four amino acids (glycine, glutamine, proline, and arginine) and palmitic acid (which helps it penetrate skin more effectively).
This ingredient helps reduce inflammation by limiting the production of interleukin-6 (IL-6), a chemical that triggers inflammatory responses, particularly after UV exposure.
Less inflammation = slower collagen breakdown and a longer-lasting, youthful appearance.
Palmitoyl Tetrapeptide-7 also stimulates collagen production and supports a healthier skin barrier.
Over time, this can improve skin firmness, hydration, and reduce the appearance of fine lines. It’s commonly paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.
This ingredient has been shown to be effective and safe in cosmetic use and you'll typically find it in small amounts (less than 0.01%).
Due to its palmitic acid base, it may not be safe for Malassezia folliculitis.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tetrapeptide-7Palmitoyl Tripeptide-1 is also known as pal-GHK. It is made up of 3 amino acids and palmitic acid, a fatty acid that helps it absorb into skin more easily.
This peptide is as a signal peptide, meaning it tells the skin to produce more collagen. Collagen is the key protein that helps form the skin's structure and keep it plump, firm, and hydrated.
By boosting collagen production, this ingredient supports a stronger skin barrier and helps reduce the appearance of wrinkles.
You'll most likely see this ingredient paired with Palmitoyl Tetrapeptide-7 in the well-known Matrixyl 3000 complex. While results from in-house testing should be viewed cautiously, this peptide duo is among the most studied and widely used in modern skincare.
Due to its palmitic acid base, this ingredient may not be safe for Malassezia folliculitis.
Read more about other common types of peptides here:
Learn more about Palmitoyl Tripeptide-1This synthetic, signal peptide has unique skin conditioning properties in that is a matrikine-mimetic compound.
First of all, Palmitoyl Tripeptide-38 is a signal peptide; signal peptides tell the body to create more collagen.
What is a matrikine-mimetic compound?
This peptide has the ability to mimic matrikines in skin. Our skin created matrikines by breaking down matrix proteins into peptides.
Matrikines play a role in:
Though further research is needed, this ingredient seems pretty promising. In one study, women over the age of 40 with visible photoaging used a vitamin C serum with this ingredient for 56 days (15% ascorbid acid, 5 ppm palmitoyl tripeptide‐38). The results found improvement in skin roughness and skin tone.
This peptide is also part of the famous Matrixyl synthe’6, a blend of ingredients that also includes glycerin, water, and hydroxypropyl cyclodextrin.
Learn more about Palmitoyl Tripeptide-38This synthetic peptide is created from lysine, valine, and palmitic acid.
According to the manufacturer, in-vitro studies show tissue growth and collagen synthesis. Another in-vivo study found 60 volunteers saw a significant reduction in wrinkles after 84 days.
Due to its palmitic acid base, this peptide may not be fungal-acne safe.
Learn more about Palmitoyl Tripeptide-5Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Stay hydrated!
Learn more about WaterIngredient Ratings
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When to use
Medik8 Liquid Peptides 33 ingredients
Numbuzin No.9 NAD+ PDRN Glow Boosting Toner 125 ingredients
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