This anti-aging ampoule is formulated around Niacinamide and Adenosine to soften the look of wrinkles and refine skin texture.
This anti-aging serum is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and refine skin texture.
What's inside
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Skin ConditioningGlycerin
Humectant
Butylene Glycol
Humectant
Niacinamide
Smoothing
Sodium Lactate
Buffering
1,2-Hexanediol
Skin Conditioning
Gellan Gum
PEG-60 Hydrogenated Castor Oil
Emulsifying
Ethylhexylglycerin
Skin ConditioningAdenosine
Skin Conditioning
Disodium EDTA
ChelatingActinidia Chinensis Fruit Extract
EmollientEucalyptus Globulus Leaf Extract
Perfuming
Centella Asiatica Extract
Cleansing
Golden Extract
Polygonum Cuspidatum Root Extract
Antioxidant
Propanediol
Solvent
Glycyrrhiza Glabra Root Extract
Bleaching
Camellia Sinensis Leaf Extract
Antimicrobial
Sodium Hyaluronate Crosspolymer
Humectant
Rosmarinus Officinalis Leaf Extract
AntimicrobialFructan
Skin ConditioningChamomilla Recutita Extract
Skin Conditioning
Sodium Hyaluronate
Humectant
Hydrolyzed Glycosaminoglycans
HumectantGlycine
Buffering
Caprylyl Glycol
Emollient
Polysorbate 80
Emulsifying
Serine
Masking
Glutamic Acid
Humectant
Hydrolyzed Elastin
EmollientEctoin
Skin Conditioning
Hydrogenated Polyisobutene
EmollientBenzyl Glycol
SolventAspartic Acid
Masking
Leucine
Skin ConditioningOryza Sativa Extract
Absorbent
Astaxanthin
Skin Conditioning
Hydrolyzed Hyaluronic Acid
Humectant
Alanine
Masking
Lysine
Skin ConditioningArginine
Masking
Tyrosine
MaskingPhenylalanine
Masking
Valine
MaskingThreonine
Proline
Skin Conditioning
Isoleucine
Skin ConditioningHistidine
Humectant
Methionine
Skin ConditioningCysteine
Antioxidant
Palmitoyl Tetrapeptide-7
Skin Conditioning
Hydrolyzed Sodium Hyaluronate
Skin Conditioning
Hydrolyzed Collagen
Emollient
Acetyl Octapeptide-3
Humectant
Tripeptide-1
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Pentapeptide-4
Skin Conditioning
Copper Tripeptide-1
Skin Conditioning
Acetyl Hexapeptide-8
Humectant
Sodium Benzoate
Masking
Sodium Acetylated Hyaluronate
Humectant
Hexapeptide-9
Skin Conditioning
Hydroxypropyltrimonium Hyaluronate
Hyaluronic Acid
Humectant
Dimethylsilanol Hyaluronate
Humectant
Nonapeptide-1
Skin Conditioning
Pentylene Glycol
Skin Conditioning
Hair Extract
Potassium Hyaluronate
Skin ConditioningTocopherol
Antioxidant
Alcohol
Antimicrobial
Parfum
Masking
Water, Glycerin, Butylene Glycol, Niacinamide, Sodium Lactate, 1,2-Hexanediol, Gellan Gum, PEG-60 Hydrogenated Castor Oil, Ethylhexylglycerin, Adenosine, Disodium EDTA, Actinidia Chinensis Fruit Extract, Eucalyptus Globulus Leaf Extract, Centella Asiatica Extract, Golden Extract, Polygonum Cuspidatum Root Extract, Propanediol, Glycyrrhiza Glabra Root Extract, Camellia Sinensis Leaf Extract, Sodium Hyaluronate Crosspolymer, Rosmarinus Officinalis Leaf Extract, Fructan, Chamomilla Recutita Extract, Sodium Hyaluronate, Hydrolyzed Glycosaminoglycans, Glycine, Caprylyl Glycol, Polysorbate 80, Serine, Glutamic Acid, Hydrolyzed Elastin, Ectoin, Hydrogenated Polyisobutene, Benzyl Glycol, Aspartic Acid, Leucine, Oryza Sativa Extract, Astaxanthin, Hydrolyzed Hyaluronic Acid, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Valine, Threonine, Proline, Isoleucine, Histidine, Methionine, Cysteine, Palmitoyl Tetrapeptide-7, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Collagen, Acetyl Octapeptide-3, Tripeptide-1, Palmitoyl Tripeptide-1, Palmitoyl Pentapeptide-4, Copper Tripeptide-1, Acetyl Hexapeptide-8, Sodium Benzoate, Sodium Acetylated Hyaluronate, Hexapeptide-9, Hydroxypropyltrimonium Hyaluronate, Hyaluronic Acid, Dimethylsilanol Hyaluronate, Nonapeptide-1, Pentylene Glycol, Hair Extract, Potassium Hyaluronate, Tocopherol, Alcohol, Parfum
Water
Skin ConditioningGlycerin
Humectant
Butylene Glycol
Humectant
Pentylene Glycol
Skin Conditioning
Polyglyceryl-6 Stearate
Emollient
Caprylic/Capric Triglyceride
Masking
Panthenol
Skin Conditioning
Dicaprylyl Carbonate
EmollientDicaprylyl Ether
Emollient
Potassium Cetyl Phosphate
EmulsifyingPolyglyceryl-6 Behenate
Emulsion Stabilising
Tetrapeptide-21
Skin Conditioning
Palmitoyl Tripeptide-1
Skin Conditioning
Palmitoyl Tetrapeptide-7
Skin Conditioning
Palmitoyl Tripeptide-38
Skin Conditioning
Copper Palmitoyl Heptapeptide-14
Skin Conditioning
Heptapeptide-15 Palmitate
Skin Conditioning
Saccharide Isomerate
Humectant
Allantoin
Skin Conditioning
Cetearyl Alcohol
Emollient
Glyceryl Stearate Se
Emulsifying
Tapioca Starch
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingCarbomer
Emulsion StabilisingPolysorbate 20
Emulsifying
Hydroxypropyl Cyclodextrin
MaskingLactic Acid/Glycolic Acid Copolymer
Skin ConditioningPolyvinyl Alcohol
Citric Acid
Buffering
Sodium Citrate
BufferingSodium Hydroxide
BufferingPhenoxyethanol
Preservative
Ethylhexylglycerin
Skin ConditioningWater, Glycerin, Butylene Glycol, Pentylene Glycol, Polyglyceryl-6 Stearate, Caprylic/Capric Triglyceride, Panthenol, Dicaprylyl Carbonate, Dicaprylyl Ether, Potassium Cetyl Phosphate, Polyglyceryl-6 Behenate, Tetrapeptide-21, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Saccharide Isomerate, Allantoin, Cetearyl Alcohol, Glyceryl Stearate Se, Tapioca Starch, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Polysorbate 20, Hydroxypropyl Cyclodextrin, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Citric Acid, Sodium Citrate, Sodium Hydroxide, Phenoxyethanol, Ethylhexylglycerin
Reviews
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinPalmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging".
"Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age.
This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin.
Clinical testing showed statistically significant improvements in:
Studies also found the more of this ingredient used, the more your skin produces Collagen I, fibronectin, and hyaluronic acid.
You'll likely see this ingredient paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.
A 3% concentration applied twice daily for two months showed meaningful skin rejuvenation results in clinical panels.
Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.
That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.
Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.
In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.
Human clinical data is promising, but modest:
A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.
A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.
You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.
Fungal acne note:
Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolWater. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about Water
