MEDI-PEEL Retinol Collagen Lifting Cream
A moisturizer with 63 ingredients, including retinoid, niacinamide, and vitamin E.
This anti-aging moisturizer is formulated around Niacinamide and Retinyl Retinoate to soften the look of wrinkles and refine skin texture.
Worth noting
Contains a retinoid, which is best introduced gradually.
We independently verify ingredients, backed by peer-reviewed research. Suggest an update.
What's inside
Ingredients List
Water
Skin ConditioningGlycerin
HumectantEthylhexyl Palmitate
EmollientCetyl Ethylhexanoate
EmollientGlycereth-26
HumectantDipropylene Glycol
HumectantNiacinamide
SmoothingButylene Glycol
HumectantPalmitic Acid
EmollientC14-22 Alcohols
Emulsion StabilisingCaprylic/Capric Triglyceride
MaskingC12-20 Alkyl Glucoside
Emulsifying1,2-Hexanediol
Skin ConditioningPropanediol
SolventRetinyl Palmitate
Skin ConditioningRetinyl Retinoate
Skin ConditioningHydroxypinacolone Retinoate
Skin ConditioningMadecassoside
AntioxidantCamellia Japonica Flower Extract
EmollientSolanum Lycopersicum Fruit Extract
AntioxidantDiethylhexyl Syringylidenemalonate
Skin ProtectingBenzotriazolyl Dodecyl P-Cresol
UV AbsorberGlucose
HumectantPanthenol
Skin ConditioningDipotassium Glycyrrhizate
HumectantSh-Polypeptide-121
Skin ConditioningDiisopropyl Adipate
EmollientAnastatica Hierochuntica Extract
AstringentLecithin
EmollientPPG-13-Decyltetradeceth-24
EmulsifyingArachis Hypogaea Oil
Skin ConditioningSilybin
Skin ConditioningRetinal
Skin ConditioningRetinol
Skin ConditioningBHT
AntioxidantSoluble Collagen
HumectantPolyglyceryl-10 Behenate/Eicosadioate
EmulsifyingIsopropyl Lauroyl Sarcosinate
Skin ConditioningCyanocobalamin
Skin ConditioningCaramel
Cosmetic ColorantTocopherol
AntioxidantPentylene Glycol
Skin ConditioningBHA
AntioxidantDecyl Glucoside
CleansingPolysorbate 60
EmulsifyingPolysorbate 20
EmulsifyingSorbitan Stearate
EmulsifyingGlycereth-25 PCA Isostearate
EmulsifyingSorbitan Isostearate
EmulsifyingXanthan Gum
EmulsifyingAcrylates/C10-30 Alkyl Acrylate Crosspolymer
Emulsion StabilisingHydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Emulsion StabilisingGlyceryl Acrylate/Acrylic Acid Copolymer
HumectantAmmonium Acryloyldimethyltaurate/Vp Copolymer
Tromethamine
BufferingStearic Acid
CleansingPotassium Sorbate
PreservativePentaerythrityl Tetraethylhexanoate
EmollientDisodium EDTA
Hydroxyacetophenone
AntioxidantCaprylyl Glycol
EmollientEthylhexylglycerin
Skin ConditioningParfum
MaskingWater, Glycerin, Ethylhexyl Palmitate, Cetyl Ethylhexanoate, Glycereth-26, Dipropylene Glycol, Niacinamide, Butylene Glycol, Palmitic Acid, C14-22 Alcohols, Caprylic/Capric Triglyceride, C12-20 Alkyl Glucoside, 1,2-Hexanediol, Propanediol, Retinyl Palmitate, Retinyl Retinoate, Hydroxypinacolone Retinoate, Madecassoside, Camellia Japonica Flower Extract, Solanum Lycopersicum Fruit Extract, Diethylhexyl Syringylidenemalonate, Benzotriazolyl Dodecyl P-Cresol, Glucose, Panthenol, Dipotassium Glycyrrhizate, Sh-Polypeptide-121, Diisopropyl Adipate, Anastatica Hierochuntica Extract, Lecithin, PPG-13-Decyltetradeceth-24, Arachis Hypogaea Oil, Silybin, Retinal, Retinol, BHT, Soluble Collagen, Polyglyceryl-10 Behenate/Eicosadioate, Isopropyl Lauroyl Sarcosinate, Cyanocobalamin, Caramel, Tocopherol, Pentylene Glycol, BHA, Decyl Glucoside, Polysorbate 60, Polysorbate 20, Sorbitan Stearate, Glycereth-25 PCA Isostearate, Sorbitan Isostearate, Xanthan Gum, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glyceryl Acrylate/Acrylic Acid Copolymer, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Tromethamine, Stearic Acid, Potassium Sorbate, Pentaerythrityl Tetraethylhexanoate, Disodium EDTA, Hydroxyacetophenone, Caprylyl Glycol, Ethylhexylglycerin, Parfum
Key Ingredients
Benefits
Concerns
Ingredients Explained
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!
Learn more about WaterGlycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Learn more about GlycerinEthylhexyl Palmitate, also known as octyl palmitate, is created from 2-ethylhexyl alcohol and palmitic acid.
In cosmetics, it plays many roles:
One thing worth noting: a controlled study found this ingredient applied under occlusion to acne-prone subjects increased microcomedones. Just keep in mind this was under occlusive conditions and don't reflect how most products are used day-to-day.
For most people, this is a well-tolerated and lightweight ingredient.
This ingredient may not be fungal acne safe because it is an ester of palmitic acid, a C16 fatty acid that falls within the C11-24 range that Malassezia can metabolize.
Learn more about Ethylhexyl PalmitateCetyl Ethylhexanoate is an emollient ester. It comes from cetearyl alcohol and 2-ethylhexanoic acid.
Cetyl Ethylhexanoate is an emollient that adds a velvety feel to skin without being greasy or oily. Emollients help trap moisture into your skin, keeping your skin soft and hydrated.
Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.
It is a humectant and helps add texture to products. It can make your product thicker.
As a humectant, it helps draw moisture from the air to your skin. This helps your skin stay hydrated.
Learn more about Glycereth-26Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.
This ingredient helps:
Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.
As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.
Studies show Dipropylene Glycol is considered safe to use in skincare.
Learn more about Dipropylene GlycolNiacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Learn more about NiacinamideButylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Learn more about Butylene GlycolPalmitic Acid is a fatty acid naturally found in our skin and in many plant and animal sources.
In cosmetics, it is usually derived from palm oil. It serves many purposes in skincare, acting as a cleanser, emollient, and emulsifier.
Interestingly, topically applied Palmitic Acid can be elongated into longer chain fatty acids and ceramides. A 2019 study found low levels of Palmitic Acid lead to slower development of cells, suggesting it plays a role in keeping your skin's renewal process on track.
The CIR (Cosmetic Ingredient Review) panel determined it safe as used in cosmetics at concentrations up to 13%. It is non-irritating and non-sensitizing in clinical studies.
The culprit behind fungal acne, the Malassezia yeast, feeds on fatty acids with carbon chain lengths between C11-C24. Palmitic Acid, at C16, falls right into that sweet spot.
In vitro studies have shown that Palmitic Acid is one of the fatty acids that induce rapid Malassezia growth in lab settings.
It's worth noting that what feeds yeast in a lab doesn't necessarily feed it on your face since formulation and your skin's chemistry play a bigger role.
Learn more about Palmitic AcidThis ingredient is a blend of long-chain fatty alcohols (myristyl, cetyl, stearyl, arachidyl, and behenyl). It is an emulsion stabilizer with emollient properties.
Don't let the word "alcohol" scare you: fatty alcohols are nothing like the drying solvents. This ingredient actually helps soften and smooth the skin.
By the way, the FDA allows products to be labeled "alcohol-free" even when they contain fatty alcohols like this one.
In a formula, it prevents the water and oil phases from separating over time while also contributing to a pleasant, non-greasy slip.
Interestingly, this ingredient can organize into the structures that mimic the skin's own lipid architecture to help support barrier function and reduce transepidermal water loss (TEWL).
The CIR Expert Panel has thoroughly assess the individual fatty alcohols that make up this blend and found no significant toxicity or dermal irritation.
Fungal acne: Research has shown the Malassezia can grow in the presence of fatty alcohols with the chain length between C12-24, making this ingredient not fungal acne safe.
Learn more about C14-22 AlcoholsCaprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.
Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.
In practice, that translates to a long shelf life and a consistently elegant skin feel.
While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.
Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.
This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.
This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.
Learn more about Caprylic/Capric TriglycerideWe don't have a description for C12-20 Alkyl Glucoside yet.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
- Humectant, drawing moisture into the skin
- Emollient, helping to soften skin
- Solvent, dispersing and stabilizing formulas
- Preservative booster, enhancing the antimicrobial activity of other preservatives
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Learn more about PropanediolRetinyl Palmitate is a form of retinoid. Retinoids are the superstar class of anti-aging ingredients that include Tretinoin and Retinol.
This particular ingredient has had a bumpy year with its rise and fall in popularity.
First, Retinyl Palmitate is created from Palmitic Acid and Retinol. It is a Retinol ester and considered one of the weaker forms of retinoid.
This is because all retinoids have to be converted to Tretinoin, AKA Retinoic Acid.
Retinyl Palmitate is pretty far down the line and has to go through multiple conversions before its effects are seen. Once it's on your skin, enzymes called esterases convert it into Retinol, then into Retinal, and finally into Retinoic Acid; that's three steps with a little lost at each one.
The benefits of Retinyl Palmitate are debated due to this long and ineffective conversion line.
So why use it at all?
The answer is stability. Retinol and Retinoic Acid break down fast when they hit light, heat, and air, and Retinoic Acid can be pretty irritating on top of that.
Retinyl Palmitate is much more stable and gentler, making it easier to formulate with and easier on sensitive skin (even if it's weaker gram for gram).
Studies show Retinyl Palmitate to help:
Newer research from 2023-2025 also found that Retinyl Palmitate works especially well when paired with Retinol. The two seem to cover each other's weak spots; retinol brings the potency while Retinyl Palmitate brings the stability and gentleness. Together, they repair UV damage better than either one does alone.
This ingredient used to be found in sunscreens to boost the efficacy of sunscreen filters.
The downfall of Retinyl Palmitate was due to released reports about the ingredient being correlated to sun damage and skin tumors.
Most of this traces back to a 2012 US National Toxicology Program (NTP) study where hairless mice coated in Retinyl Palmitate cream and exposed to UV light developed skin tumors faster.
Here's the nuance, though.
When the Cosmetic Ingredient Review (CIR) Expert Panel went back through that study, they found methodological flaws and decided the results couldn't be interpreted as proof of extra risk.
The EU's Scientific Committee on Consumer Safety (SCCS) said the mouse findings might point to a concern but they're hard to apply to humans since hairless mouse skin and human skin behave differently.
While there is a study showing this ingredient to cause DNA damage when exposed to UVA, there is no concrete proof of it being linked to skin cancer. It is completely safe to use when used correctly.
Both the CIR and the SCCS consider it safe at the concentrations used in cosmetics; the SCCS specifically cleared retinoids up to 0.05% in body lotions and 0.3% in face creams, hand creams, and rinse-off products.
As of 2025, the EU has written those limits into law, plus a label warning about your total Vitamin A intake from all sources.
All retinoids increase your skin's sensitivity to the sun in the first few months of usage. Be especially careful with reapplying sunscreen when using any form of retinoid.
One more note: if you're pregnant, high doses of Vitamin A can be a concern, so a lot of people skip topical retinoids (including Retinyl Palmitate) during pregnancy just to be safe. Check with your doctor if you're unsure.
Fun fact: This ingredient is often added to low-fat milk to increase the levels of Vitamin A.
Learn more about Retinyl PalmitateRetinyl Retinoate is a new member of the retinoid family. It is created by combining retinoic acid (aka Tretinoin) and retinol.
Upcoming research shows this ingredient to be as effective but less irritating than retinol. Retinoids are the anti-aging gold standard of the skincare world.
All retinoids are inactive until they are converted into retinoic acid, a biologically active drug.
Retinoids undergo a conversion process until it reaches the last step, which is retinoic acid. Therefore, retinoic acid/Tretinoin is the most effective of all retinoids because it does not need to be converted.
Retinyl Retinoate is immediately broken down into retinoic acid and retinol, therefore becoming active right away.
Retinoids are best used to:
Further research is needed for this upcoming ingredient, but the results look promising so far.
Learn more about Retinyl RetinoateHydroxypinacolone Retinoate (aka Granactive Retinoid or HPR) is a retinoid that is part of the same vitamin A family as retinol.
It is an ester of retinoic acid that binds directly to your skin's retinoic acid receptors so it doesn't need your skin to convert it through several steps before it can do anything.
In practice, this means it does the classic retinoid jobs in a formula:
The best part is that it can do all this with noticeably less redness, flaking, and stinging than traditional retinoids.
That gentle reputation is backed by lab work as well; a 2018 study on skin models found that HPR triggered higher retinoid-gene activity than retinol, retinal, or retinyl propionate at the same concentrations while being less irritating to cells.
It also boosted procollagen production to levels similar to retinoic acid itself.
A 2023 study showed HPR works synergistically with retinyl propionate to switch on collagen-building pathways and a 2025 clinical serum study in women with mild photoaging saw improvements in wrinkles and elasticity (though that formula also contained retinol, peptides, and Silybin).
One naming quirk worth mentioning:
You'll likely see this ingredient sold under the trade name "Granactive Retinoid", which is actually only 10% HPR blended with 90% Dimethyl Isosorbide solvent. This means a 5% Granactive Retinoid really only means about 0.5% HPR.
Finished products typically land somewhere between 0.05-1% and it's happiest formulated at a mildly acidic to neutral pH (~5.5-6.5).
Another perk is that this is one of the more light- and temperature-stable retinoids which is a nice bonus for shelf life.
Learn more about Hydroxypinacolone RetinoateMadecassoside is one of four active compounds found in Centella asiatica and is one of the main reasons Centella is so effective at calming irritated skin and supporting the moisture barrier.
There's a solid body of peer-reviewed research backing Madecassoside for several skin benefits. Studies have found:
Madecassoside pairs well with other hydrating or antioxidant ingredients like Ascorbic Acid or Hyaluronic Acid.
Learn more about MadecassosideCamellia Japonica Flower Extract comes from the Japanese Camellia plant. This plant is native to East Asia and known as "Tsubaki" in Japanese.
Tsubaki flowers possess antioxidant and soothing properties. This flower has shown to be effective at fighting pollution damage by protecting your skin's fibroblasts. Your skin's fibroblasts help create collagen and collagen is responsible for youthful, plump skin.
This flower also contains many antioxidant enzymes. Antioxidants help fight free-radical molecules. Free-radical molecules are capable of damaging our cells and other genetic material. They may originate from sunlight, air pollution, or cigarette smoke. These free-radical molecules are unstable and are often looking for missing electrons. This instability causes free-radicals to damage our cells. Antioxidants help stabilize free-radicals by donating extra electrons.
Thus, Camellia Japonica Flower Extract may help reduce the signs of aging.
Learn more about Camellia Japonica Flower ExtractThis ingredient is also known as tomato fruit extract. It comes from ripe tomatoes and is rich in antioxidants.
According to a manufacturer, the antioxidants of this ingredients help sooth irritation and redness while protecting skin from free radical damage.
Diethylhexyl Syringylidenemalonate (DESM) is a photostabilizer, antioxidant, and SPF booster.
One of DESM's main roles is stabilizing UV filters, especially avobenzone. Avobenzone is notoriously unstable when exposed to sunlight. By enhancing the stability of these filters, DESM helps maintain the sunscreen's effectivess through wear. It also helps improve protection against long-wave UVA rays by increasing the wavelength of the formula.
Besides enhancing UVA protection, DESM can boost the SPF of high-SPF formulations by up to 5 units.
DESM also preserves the color integrity of cosmetic products and helps reduce the chance of yellowing of fading due to light exposure.
This ingredient is typically found in concentrations between 0.3% - 0.5%. There are currently no maximum usage limits by regulatory bodies.
Though this ingredient is a chemical UV filter, it can often be found in "100% mineral" sunscreens. This is due to regulatory loopholes.
Learn more about Diethylhexyl SyringylidenemalonateBenzotriazolyl Dodecyl P-Cresol, also known as Tinogard TL, is a broad-spectrum UV absorber.
It helps stabilize light-sensitive ingredients and protects other ingredients from breaking down due to light exposure (especially in transparent packaging).
This ingredient helps extend a product’s shelf life by preventing both photolytic (light-induced) and photo-oxidative degradation. It’s typically used at low concentrations, around 0.01% to 0.1%.
Despite being a chemical UV filter, this ingredient can be found in "100% mineral sunscreens". This is due to regulatory loopholes.
Learn more about Benzotriazolyl Dodecyl P-CresolGlucose is a simple sugar (a monosaccharide). In skincare, it is mostly a humectant and skin conditioning agent.
Mechanistically, it has multiple hydroxyl groups that hydrogen-bond to water. This pulls moisture into the upper layers of skin to keep the surface soft and hydrated.
It's worth knowing sugars are already a natural component of the skin's NMF (natural moisturizing factor) so it's a molecule that your stratum corneum is well-acquainted with.
Just so you know, glucose is hydrophilic (water-loving) and the stratum corneum is a strong barrier to hydrophilic compounds. This just means penetration is slow and most of the action is happening on the surface.
Gram-to-gram, glucose is not as efficient as a humectant as glycerin. This is why you'll likely see glycose paired with stronger humectants for a bigger hydration payoff.
In skincare, glucose is typically derived from corn or other starch sources.
Learn more about GlucosePanthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.
There are two forms of panthenol: D and L.
D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.
Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):
Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.
This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.
Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.
This ingredient is also referred to as pro-vitamin B5.
Learn more about PanthenolDipotassium Glycyrrhizate comes from licorice root.
Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.
One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.
Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.
Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.
Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.
Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.
Learn more about Dipotassium GlycyrrhizateSh-Polypeptide-121 is a peptide.
Diisopropyl Adipate comes from isopropyl alcohol and Adipic Acid.
It is a solvent and emollient. As a solvent, it is used to help other ingredients dissolve into the solution. It is also often used to soften hard ingredients.
Emollients help hydrate the skin by creating a thin barrier. This thin barrier prevents moisture from escaping.
Learn more about Diisopropyl AdipateAnastatica Hierochuntica Extract is from a plant called the Rose of Jericho. This plane is found in the deserts of the Middle East and North Africa.
Anastatica Hierochuntica Extract has antioxidant properties. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Learn more about LecithinWe don't have a description for PPG-13-Decyltetradeceth-24 yet.
Arachis Hypogaea Oil is the INCI name for peanut oil.
It's an emollient that contains oleic acid (~57%), linoleic acid (~26%), and small amounts of palmitic, stearic, arachidic, vitamin E, and other types of acids.
In skincare, it mostly softens, smooths, and slows water loss.
For those with a peanut allergy: Cosmetic-grade peanut oil is refined to strip out the proteins that trigger peanut allergies. But always be sure to patch test if you're unsure or have a severe allergy.
Clinical studies have repeatedly found that highly refined peanut oil doesn't cause reactions in the vast majority of peanut-allergic people.
Just know: unrefined or cold pressed version can still contain the allergenic protein.
We recommend reaching out to the brand about their source of peanut oil if you have questions.
Learn more about Arachis Hypogaea OilWe don't have a description for Silybin yet.
Retinal (aka retinaldehyde) is a form of retinoid that formulators use mainly as an antiaging and skin-renewing active.
What makes it special is its position in the retinoid family; skin converts it to retinoic acid (the prescription gold standard) in just one step.
Because retinal only requires 1 conversion step to become retinoic acid, it's the strongest over-the-counter retinoid. It also works at lower concentrations than retinol, since retinal is about 10x more bioavailable.
Studies back up its efficacy in skin:
A foundational trial showed that applying 0.05-0.5% retinal for 1-3 months produced a dose-dependent and significant increase in epidermal thickness + cell turnover markers.
And a head-to-head comparison of 0.05% retinal against a 0.05% retinoid acid found both formulations were effective for the basis of wrinkle/skin roughness features, but retinoic acid caused more local irritation.
More recent controlled trials confirm it improves wrinkles, dermal density, and firmness over 12-24 weeks, with significant improvements in skin texture and firmness (particularly with the higher 0.1% concentration).
Retinal also has one trick the other retinoids do not: it directly fights against acne bacteria since a clinical study showed retinaldehyde-treated areas displayed a significant decrease in counts of viable P. acnes.
This makes it a great pick for people who want to treat aging and breakouts.
Typical cosmetic use sits in the 0.05-0.1% range with 0.05% being the gentle starting point and 0.1% giving stronger results.
Like all retinoids, retinal works best with nightly use, a good moisturizer, and daytime sunscreen. It can cause some irritation so ease into it slowly rather than going all in.
The "ramp up" method works well: start with Retinal once a week to give your skin time to adjust, which keeps irritation low.
Slowly add more nights until you reach your goal frequency once your skin feels comfortable.
Retinoids also make your skin more sensitive to the sun in the first few weeks, so wear sunscreen every morning and protect your skin from direct sun while you build up tolerance.
Learn more about RetinalRetinol is one of the most studied anti-aging ingredients in skincare (and for good reason!).
It's a form of vitamin A that your skin converts into Retinoic Acid, the active molecule that actually does the work in your cells.
That conversion happens in two steps: your skin first turns Retinol into Retinaldehyde (also called Retinal), then turns Retinaldehyde into Retinoic Acid.
Retinol is converted to biologically active retinoic acid via retinaldehyde by dehydrogenases in a two-step oxidation process.
Each step is a little "upgrade" toward the active form which is part of why Retinol is gentler than prescription Retinoic Acid; your skin does the work gradually. This also explains where Retinol sits in the retinoid family.
Here is the retinoid family ranked roughly by strength: Retinyl Esters (like Retinyl Palmitate) < Retinol < Retinaldehyde < Retinoic Acid.
Retinoid activity increases in that order, while tolerance runs in reverse; retinyl esters are the gentlest and retinoic acid the most irritating.
The more conversion steps an ingredient needs, the gentler (and slower) it tends to be, so Retinol lands in a nice middle spot. It's more effective than the esters, gentler than prescription options.
Once it becomes Retinoic Acid, it binds to receptors inside your cells' nuclei (called RARs and RXRs). These receptor pairs bind to specific DNA motifs called retinoic acid response elements and act like switches that turn certain genes on or off.
In practice, this means a few things happen in a formula. It:
That last two are worth a closer look.
A study that tested Retinol directly (not just prescription Retinoic Acid) found that four weeks of retinol thickened the epidermis and switched on the genes for Collagen I and Collagen III, with more procollagen I and III showing up in the skin. And after twelve weeks, facial wrinkles were visibly reduced.
Retinoids more broadly stimulate the skin's synthesis of hyaluronan and other glycosaminoglycans, part of what gives skin a plumper, more hydrated look over time.
So even the gentler OTC form is doing real structural work (not just sitting on the surface).
It's also worth knowing Retinol isn't only a wrinkle ingredient; it can help with uneven tone, dark spots, rough texture, and the look of pores as well because it speeds up turnover and influences pigment.
The research backs this up as well.
A pooled analysis of six clinical studies found that 0.1% stabilized retinol improved all signs of photoaging versus vehicle as early as week 4 and through 12 weeks, with only a few mild cases of irritation.
Another study comparing concentrations found that 0.3% and 1% Retinol were similarly effective at remodeling photodamaged skin, but 0.3% caused fewer adverse reactions when used daily (a useful reminder that more isn't always better).
Retinol is about tenfold less potent than Retinoic Acid. This is why it works as a gentler, non-prescription option that builds results over time.
Typical concentrations range from 0.1-1%, with 0.1% to 0.3% being a well-supported sweet spot for visible benefits with good tolerability.
One quirk worth mentioning: Retinol is famously unstable.
It's highly sensitive to light and oxygen, and UV exposure breaks it down into a range of degradation products.
Real-world testing bears this out, with retinoid content in some products dropping anywhere from 0% to 80% after six months at room temperature, and even more at higher temperatures.
This is why good formulations lean on opaque, air-tight packaging (think tubes and pumps, not clear jars) and often "encapsulate" the Retinol to shield it.
Signs of oxidation include your product turning yellow or smelling "off". Keeping it somewhere cool and dark, and using it up within a few months of opening helps it stay effective.
The most common side effects are mild and temporary: usually some dryness, redness, or light peeling as your skin adjusts. These tend to settle with consistent and lower-frequency use.
Like all retinoids, Retinol works best with nightly use, a good moisturizer, and daytime sunscreen.
The "ramp up" method works well: start with Retinol once a week to give your skin time to adjust, which keeps irritation low. Slowly add more nights until you reach your goal frequency once your skin feels comfortable.
Retinoids also make your skin more sensitive to the sun in the first few weeks, so wear sunscreen every morning and protect your skin from direct sun while you build up tolerance.
One safety note: topical Retinoids aren't recommended during pregnancy or breastfeeding. Systemic absorption from creams is low but because high oral vitamin A is a known teratogen and topical safety data are limited, most clinicians recommend stopping retinoids when pregnant or trying to conceive.
Learn more about RetinolBHT is a synthetic antioxidant and preservative.
As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells.
As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.
The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.
However, it was recently restricted for use in the UK as of April 2024.
Learn more about BHTSoluble collagen is a large, water-loving protein typically extracted from cattle hides or marine sources like fish skin.
In cosmetics, it works purely as a humectant and film-former.
Despite the marketing that surrounds the word "collagen", its molecule is far too large to penetrate skin so it can't rebuild the collagen in your dermis.
Instead, it sits on the surface and binds water to help reduce transepidermal water loss and leave skin feeling soft, plump, and temporarily tightened.
Suppliers commonly recommend using it around 3-6% though industry data shows concentrations are often much lower (down to a fraction of a percent).
This ingredient has been found safe to use in cosmetics with no reported irritation, sensitization, or phototoxicity.
Learn more about Soluble CollagenWe don't have a description for Polyglyceryl-10 Behenate/Eicosadioate yet.
We don't have a description for Isopropyl Lauroyl Sarcosinate yet.
Cyanocobalamin is the manufactured version of vitamin B12. It has skin soothing, antioxidant, and barrier protecting properties. Topical cyanocobalamin is used to treat skin irritation and atopic dermatitis.
We don't have a description for Caramel yet.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Learn more about TocopherolPentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Learn more about Pentylene GlycolThe ingredient "BHA" stands for butylated hydroxyanisole. If you are looking for the beta-hydroxy acid, aka as Salicylic Acid, click here.
In cosmetics, butylated hydroxyanisole is used as a perservative. It also has antioxidant properties. The concentrations usually used in skincare are low and do not penetrate through skin.
It is only considered a carcinogen when ingested.
Butylated Hydroxyanisole is a synthetic and waxy petrochemical. It is used as a preservative in foods and cosmetics.
Learn more about BHADecyl Glucoside is a plant-derived surfactant and emulsion stabilizer. It is created by reacting glucose with the fatty acids from plants.
Like all surfactants, it works by lowering the surface tension between water and oil. This makes it so that dirt, sebum, and makeup can be lifted off your skin and rinsed away. It also produces a dense and creamy foam.
Because it has a neutral charge, it is compatible with a wide range of ingredients and stays stable across a broad pH range/water hardiness conditions.
Patch testing has shown it to have the lowest irritation potential among common cleansing surfactants (like SLS).
Typical use levels range from 5-20% in rinse-off cleansers.
One thing worth knowing: The American Contact Dermatitis Society named the parent family, alkyl glucosides, "Allergen of the Year" in 2017. The prevalence of allergy is pretty low but be sure to patch test if you've reacted to "gentle" or sulfate-free cleansers before.
This ingredient is fungal acne safe because the fatty alcohol portion of this ingredient is not within the C11-24 chain length that Malassezia can metabolize.
Learn more about Decyl GlucosidePolysorbate 60 is used to help stabilize products. It is a surfactant and emulsifier. These properties help keep ingredients together in a product. Surfactants help reduce surface tension between ingredients with different states, such as liquids and solids. Emulsifiers help prevent oils and waters from separating.
Polysorbate 60 is sorbitol-based and created from the ethoxylation of sorbitan. Ethoxylation is a chemical reaction used to add ethylene oxide. Sorbitan is a the dehydrated version of sorbitol, a sugar found in fruits.
In this case, the 60 comes from reacting 60 units of ethylene oxide with sorbitan.
Polysorbates are commonly used in medicine and foods.
Learn more about Polysorbate 60Polysorbate 20 is a gentle, water-soluble emulsifier and mild surfactant. It stops oil and water from separating to keep your formulas blended and stable.
It also acts as a mild penetration enhancer by helping active ingredients absorb slightly better.
The common safety discussion around this ingredient involves a manufacturing byproduct called 1,4-dioxane.
Trace amounts can form during production but the EU's Scientific Committee on Consumer Safety has concluded that levels at/below 10 ppm in finished products are safe (commercial products consistently fall within acceptable margins).
True allergic reactions are uncommon and the CIR Expert Panel has confirmed this ingredient to be safe as used in cosmetics.
Because it is derived from lauric acid, it may not be fungal acne safe.
Learn more about Polysorbate 20Sorbitan Stearate is an emulsifier made by reacting sorbitol with stearic acid.
It's mostly used to keep oil and water mixed so your formulas stay smooth and stable.
The Cosmetic Ingredient Review has found 4% of this ingredient in repeat-insult patch tests on humans to be non-sensitizing. There is a caveat that some reactions have shown up in patients with damaged or diseased skin.
Because it is an ester of a C18 fatty acid, it falls into the C11-24 range that the Malassezia yeast can metabolize. This means this ingredient may not be fungal acne safe.
Learn more about Sorbitan StearateGlycereth-25 PCA Isostearate isn't fungal acne safe.
Sorbitan Isostearate is an emulsifer. It is created from isostearic acid and sorbitol.
As an emulsifier, it keeps the water and oil ingredients from separating. This keeps formulas stable and smooth.
In a 24 hour occlusive patch test on 56 subjects, 10% sorbitan isostearate was completely non-irritating. Most formulas use less than 10%.
Because it's a fatty acid ester, it may not be fungal acne safe since the Malassezia yeast can utilize it as a nutrient source.
Learn more about Sorbitan IsostearateXanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.
On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.
Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.
Learn more about Xanthan GumAcrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products.
As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied.
It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin.
A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record.
Learn more about Acrylates/C10-30 Alkyl Acrylate CrosspolymerThis is a synthetic polymer. It helps improve the texture of products by adding thickness and gel-like feel.
It is also an emulsifer, meaning it prevents ingredients such as oil and water from separating. It also helps evenly disperse other ingredients.
Glyceryl Acrylate/Acrylic Acid Copolymer is made up of glycerin and polyacrylic acid. It helps hydrate your skin as a humectant.
This ingredient forms a hydrogel that delivers moisturizing, water-based ingredients to the skin. It is also used to thicken a product and to give it a smooth texture.
Acrylic acid itself is toxic, but the polymer form (this ingredient) is too large to penetrate skin, making it non-toxic.
Learn more about Glyceryl Acrylate/Acrylic Acid CopolymerAmmonium Acryloyldimethyltaurate/Vp Copolymer is a synthetically created polymer. It's used as a film-forming agent and used to thicken the consistency of products.
Think of it as a supportive ingredient that helps your gel-creams feel silky, "cloud cream-like", and spread evenly without being greasy.
The Cosmetic Ingredient Review (CIR) Expert Panel evaluated it (along with 22 other acryloyldimethyltaurate polymers) and concluded it's:
Due to its large molecular size, it sits on the surface of skin rather than penetrating it.
Learn more about Ammonium Acryloyldimethyltaurate/Vp CopolymerTromethamine (aka THAM) is a synthetic amino acid that shows up in skincare as a helper ingredient.
It functions as a pH adjuster to help neutralize acidic ingredients and set a formula's pH to the right spot.
This matters a lot because a lot of actives (like vitamin C) needs a specific pH to work well and feel comfortable on skin.
Concentration use ranges from 0.1-1.0% depending on the formula.
Learn more about TromethamineStearic Acid is a fatty acid that is already found in your skin. It's one of the free fatty acids that works alongside ceramides and cholesterols to maintain your barrier.
In cosmetics, it is a multitasker:
Safety-wise, the CIR Expert Panel has concluded it to be safe in cosmetics when formulated to be non-irritating and non-sensitizing.
Free stearic acid is a C18 fatty acid that the Malassezia yeast can substrate, so this ingredient may not be fungal acne safe.
Learn more about Stearic AcidPotassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Learn more about Potassium SorbatePentaerythrityl Tetraethylhexanoate is an emollient that helps make your skin smooth and hydrated. It specializes in creating a non-oily and "wet" feeling on skin.
This ingredient comes from isostearic acid, a saturated fatty acid. It is a synthetic ingredient.
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Learn more about Disodium EDTAHydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster.
As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress.
Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol.
This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency.
You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase.
Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well.
An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient.
So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced.
Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable.
Learn more about HydroxyacetophenoneCaprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Learn more about Caprylyl GlycolEthylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Learn more about EthylhexylglycerinParfum is a catch-all term for an ingredient or more that is used to give a scent to products.
Also called "fragrance", this ingredient can be a blend of hundreds of chemicals or plant oils. This means every product with "fragrance" or "parfum" in the ingredients list is a different mixture.
For instance, Habanolide is a proprietary trade name for a specific aroma chemical. When used as a fragrance ingredient in cosmetics, most aroma chemicals fall under the broad labeling category of “FRAGRANCE” or “PARFUM” according to EU and US regulations.
The term 'parfum' or 'fragrance' is not regulated in many countries. In many cases, it is up to the brand to define this term.
For instance, many brands choose to label themselves as "fragrance-free" because they are not using synthetic fragrances. However, their products may still contain ingredients such as essential oils that are considered a fragrance by INCI standards.
One example is Calendula flower extract. Calendula is an essential oil that still imparts a scent or 'fragrance'.
Depending on the blend, the ingredients in the mixture can cause allergies and sensitivities on the skin. Some ingredients that are known EU allergens include linalool and citronellol.
Parfum can also be used to mask or cover an unpleasant scent.
The bottom line is: not all fragrances/parfum/ingredients are created equally. If you are worried about fragrances, we recommend taking a closer look at an ingredient. And of course, we always recommend speaking with a professional.
Learn more about ParfumReviews
No written reviews yet. Be the first to review this product.
Recent searches
Search reviews by skin type, ingredient, or keyword.
Where it's from
MEDI-PEEL is a Korean brand
Often compared with
We're dedicated to providing you with the most up-to-date and science-backed ingredient info out there.
The data we've presented on this page has been verified by a member of the SkinSort Team.
Read more about us· Updated July 29, 2025 • Added by crysv2797