Darphin Intral Soothing & Fortifying Intensive Serum

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

As a humectant, it helps the skin stay hydrated by pulling moisture to your skin. The low molecular weight of glycerin allows it to pull moisture into the deeper layers of your skin.

Hydrated skin improves your skin barrier; Your skin barrier helps protect against irritants and bacteria.

Glycerin has also been found to have antimicrobial and antiviral properties. Due to these properties, glycerin is often used in wound and burn treatments.

In cosmetics, glycerin is usually derived from plants such as soybean or palm. However, it can also be sourced from animals, such as tallow or animal fat.

This ingredient is organic, colorless, odorless, and non-toxic.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

The content of sweet almond oil makes it a great emollient; it can help soften and hydrate your skin. Emollients create a barrier over your skin to trap moisture in. Sweet almond oil has antioxidant properties.

Those with an almond allergy should be careful of this ingredient and speak with a professional about using it in your skincare.

This ingredient may not be fungal-acne safe.

As a probiotic/prebiotic/postbiotic, Lactobacillus ferment can help regular our natural biome. In fact, one study found a lack of diversity in our natural skin biome can trigger acne.

Algae is rich in antioxidants. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution.

Algae can also help with soothing and hydrating skin.

Many different types of algae have different benefits.

Bisabolol is an antioxidant. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells. By fighting these free-radicals, Bisabolol may slow down signs of aging.

Studies have shown Bisabolol to have antimicrobial properties and may be a fungicide. These properties help preserve a product's shelf life.

All these properties makes bisabolol a great skin barrier helper ingredient.

Bisabolol also helps the absorption of other ingredients.

Note: Synthetic Bisabolol has been shown to be less effective.

One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.

Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.

Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.

Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.

Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.

Studies show products formulated with NMF ingredients help strengthen our skin's barrier. Having a healthy skin barrier reduces irritation and increases hydration. Our skin barrier is responsible for having plump and firm skin. It also helps protect our skin against infection, allergies, and inflammation.

Fun fact: Phytosphingosine is abundant in plants and fungi.

More ingredients that help boost collagen in skin:

This ingredient may not be Malassezia folliculitis, or fungal-acne safe.

Sterols can be found in plants, animals, and fungi.

It is also naturally found in fruits such as apples and pears.

Sodium Hyaluronate is naturally occurring in our bodies and is mostly found in eye fluid and joints.

These are some other common types of Hyaluronic Acid:

Antioxidant components in chamomile help fight free-radical molecules. These unstable molecules may damage your skin cells. By stabilizing them, antioxidants may help reduce the signs of aging.

Ancient Greeks, Romans, and Egyptians used Chamomile to treat skin redness and dryness. Chamomile has also been used to help with stomach issues.

As an emulsifier, Sclerotium Gum helps prevent ingredients from separating, such as water and oil.

Due to it being edible and tasteless, you'll likely find this ingredient in breath freshener strips. This ingredient is produced from the starch of the fungus, Aureobasidium pullulans.

Pullulan is stable over a broad-range of pH.

Ancient Chinese medicine has used peony root to treat dark spots, but studies are looking into this claim more.

Fun fact: Betaine is naturally created in the skin and body. The kind found within cosmetic products can be either plant-derived or synthetic.

Squalane comes from squalene, which occurs naturally within the sebum of our skin. It is one of the oils our skin produces to keep itself hydrated. Squalane is the hydrogenated version of squalene and has a longer shelf life.

Research shows that squalane is non-irritating (even at 100% concentration).

In general, it's a fantastic ingredient. It does a great job at hydrating the skin, and it's suitable for those with sensitive skin.

The source of squalane may impact malassezia / fungal acne. This is because olive oil derived squalane can contain impurities such as fatty acids and plant waxes. Sugarcane derived squalane is recommended for anyone with malassezia concerns.

Is squalane vegan?

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Is squalane an oil?

Squalane is often called an oil, but it’s technically not; it’s a hydrocarbon, meaning it’s only made of carbon and hydrogen, unlike true oils which are triglycerides made of fatty acids and glycerol.

The term “oil-free” isn’t regulated, so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

While some people avoid oils thinking they cause breakouts, the right kind of oil (or oil-like ingredient like squalane) can actually help balance and hydrate your skin. It’s worth testing out simple oils or squalane to see what works best for your skin.

Some studies are looking into caffeine's ability to protect against UV rays.

One study found applying linoleic acid rich sunflower oil to be more effective at repairing the skin barrier than oleic rich olive oil.

Linoleic acid is an essential fatty acid, meaning our bodies cannot create it on its own. We need to get linoleic acid through foods such as nuts and vegetable oils.

Acne-prone skin tends to have linoleic acid and high levels of oleic acid.

Linoleic acid can also help treat acne by softening sebum to prevent clogged pores. Another study found using 2.5% linoleic acid gel for 4 weeks showed a 25% reduction in small comedones.

This ingredient can also help lighten hyperpigmentation or sun spots by disrupting the melanin production process. It also helps your skin shed melanin pigment from your skin caused by UV exposure.

Due to its role in the production of the fatty acid prostaglandin, linoleic acid can also help reduce inflammation and support wound healing.

Linoleic acid is not always fungal-acne safe; it may trigger flare-ups in sensitive individuals.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

As an emollient, lecithen helps soften the skin and creates a barrier to keep moisture in.

As an emulsifier, it also helps prevent water and oil ingredients from separating. Lecithin can also help ingredients be better absorbed by the skin.

This is because the phospholipids in lecithin produce liposomes. Liposomes help other ingredients get through the skin barrier.

Depending on the source of this ingredient, lecithin may not be fungal acne safe. This is because some sources of lecithin come from soybean oil, which may feed the malassezia yeast that feeds fungal acne.

We recommend reaching out to the brand you are purchasing from to inquire about the source of their lecithin.

Some other names for this ingredient include soy lecithin and deoiled soy lecithin.

Disodium EDTA is a salt of edetic acid and is found to be safe in cosmetic ingredients.

Your skin has a natural pH and acid mantle. This acid mantle helps prevent harmful bacteria from breaking through. The acid mantle also helps keep your skin hydrated.

"Alkaline" refers to a high pH level. A low pH level would be considered acidic.

Silica is present naturally within the skin during collagen production and when reducing inflammation.

This ingredient is hydrophobic, meaning it is not soluble in water.

Tocopheryl Acetate is commonly found in both skincare and dietary supplements.

As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation.

The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU.

However, it was recently restricted for use in the UK as of April 2024.

Another benefit is a bit of UV protection. Vitamin E helps reduce the damage caused by UVB rays. (It should not replace your sunscreen). Combining it with Vitamin C can decrease sunburned cells and hyperpigmentation after UV exposure.

You might have noticed Vitamin E + C often paired together. This is because it is great at stabilizing Vitamin C. Using the two together helps increase the effectiveness of both ingredients.

There are often claims that Vitamin E can reduce/prevent scarring, but these claims haven't been confirmed by scientific research.

Chlorphenesin is soluble in both water and glycerin.

Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.